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List of works by Michal M Masternak

17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates

scientific article published on 04 November 2019

17α-estradiol modulates IGF1 and hepatic gene expression in a sex-specific manner

scientific article published on 28 August 2020

A Long-lived Mouse Lacking Both Growth Hormone and Growth Hormone Receptor: A New Animal Model for Aging Studies.

scientific article published on 29 September 2016

Adipocytokines and lipid levels in Ames dwarf and calorie-restricted mice

scientific article published on 01 April 2006

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice

scientific article published on 8 March 2007

Blood Serum From Head and Neck Squamous Cell Carcinoma Patients Induces Altered MicroRNA and Target Gene Expression Profile in Treated Cells.

scientific article published on 11 June 2018

Caloric restriction and growth hormone receptor knockout: effects on expression of genes involved in insulin action in the heart

scientific article

Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice

scientific article

Calorie restriction during gestation affects ovarian reserve in offspring in the mouse

scientific article published on 27 November 2020

Cathepsin B Regulates Hepatic Lipid Metabolism by Cleaving Liver Fatty Acid Binding Protein

scientific article published on 19 December 2017

Changes in adipose tissue cellular composition during obesity and aging as a cause of metabolic dysregulation

scientific article published on 8 December 2016

Changes of Ovarian microRNA Profile in Long-Living Ames Dwarf Mice during Aging

scientific article

Characteristic miRNA expression signature and random forest survival analysis identify potential cancer-driving miRNAs in a broad range of head and neck squamous cell carcinoma subtypes

scientific article published on 20 November 2017

Circulating blood leukocyte gene expression profiles: effects of the Ames dwarf mutation on pathways related to immunity and inflammation

scientific article

Circulating microRNA profile in humans and mice with congenital GH deficiency

scientific article published on 12 June 2021

Circulating microRNA signature of genotype-by-age interactions in the long-lived Ames dwarf mouse

scientific article

Circulating small non-coding RNA signature in head and neck squamous cell carcinoma

scientific article

Connecting serum IGF-1, body size, and age in the domestic dog ⬇️

scientific article published on September 24, 2010

Correction to: Oral Microbial Species and Virulence Factors Associated with Oral Squamous Cell Carcinoma

scientific article published on 20 November 2020

Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice

scientific article published on 18 January 2020

Decreased expression level of apoptosis-related genes and/or proteins in skeletal muscles, but not in hearts, of growth hormone receptor knockout mice

scientific article published on February 2011

Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice.

scientific article

Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation

scientific article

Deletion of growth hormone receptor gene but not visceral fat removal decreases expression of apoptosis-related genes in the kidney-potential mechanism of lifespan extension

scientific article published on 23 March 2011

Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity

scientific article

Divergent effects of caloric restriction on gene expression in normal and long-lived mice.

scientific article published in August 2004

Dwarf Mice and Aging

scientific article published in February 2018

EFFECT OF CALORIC RESTRICTION AND RAPAMYCIN ON OVARIAN AGING IN MICE

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice

scientific article

Effect of caloric restriction and rapamycin on ovarian aging in mice

scientific article published on 29 July 2019

Effect of every other day feeding diet on gene expression in normal and in long-lived Ames dwarf mice

scientific article published in June 2005

Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.

scientific article

Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle

scientific article published in January 2007

Effects of caloric restriction and growth hormone resistance on the expression level of peroxisome proliferator-activated receptors superfamily in liver of normal and long-lived growth hormone receptor/binding protein knockout mice

scientific article published on 01 November 2005

Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice

scientific article published in August 2005

Effects of dietary restriction on the expression of insulin-signaling-related genes in long-lived mutant mice

scientific article published on January 2007

Effects of every-other-day feeding on prolactin regulatory mechanism in transgenic human growth hormone mice

scientific article

Effects of growth hormone and thyroxine replacement therapy on insulin signaling in Ames dwarf mice

scientific article

Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice

scientific article published on 08 April 2009

Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinoma

scientific article

Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent

scientific article

Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions.

scientific article

Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age.

scientific article published on 8 May 2015

Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes

scientific article

Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence

scientific article

Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver

scientific article

Growth Hormone and Aging: New Findings

scientific article published in 2021

Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice.

scientific article

Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

scientific article

Growth hormone increases DNA damage in ovarian follicles and macrophage infiltration in the ovaries

scientific article published on 05 May 2021

Growth hormone, inflammation and aging

scientific article

Growth hormone-mediated reprogramming of macrophage transcriptome and effector functions

scientific article published on 18 December 2019

Human Papillomavirus and the use of nanoparticles for immunotherapy in HPV-related cancer: A review

scientific article published on 25 September 2019

In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene

scientific article

Insulin sensitivity as a key mediator of growth hormone actions on longevity

scientific article published on 20 March 2009

Insulin sensitivity in long-living Ames dwarf mice

scientific article published on 29 August 2014

Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of calorie restriction

scientific article

Interaction of growth hormone and calorie restriction

scientific article published on 01 November 2006

Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans?

scientific article published on 25 August 2009

Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice

scientific article published on 14 July 2011

Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles

scientific article published on 11 February 2014

Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice

scientific article published in June 2005

Long-lived growth hormone receptor knockout mice show a delay in age-related changes of body composition and bone characteristics.

scientific article

Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction

scientific article published on 21 October 2004

Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure

scientific article published on 17 March 2016

Longevity is impacted by growth hormone action during early postnatal period

scientific article

Metabolic effects of intra-abdominal fat in GHRKO mice

scientific article published on 28 November 2011

MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging

scientific article

MicroRNA regulation in colorectal cancer tissue and serum

scientific article published on 30 August 2019

MicroRNAs and the metabolic hallmarks of aging

scientific article published on 3 January 2017

Molecular targets for NF1-associated malignant peripheral nerve sheath tumor

scientific article published on 27 April 2020

Multivariate analysis as an advantageous approach for prediction of the adverse outcome in head and neck microvascular reconstructive surgery

scientific article published on 9 December 2016

Non-homologous end joining induced alterations in DNA methylation: A source of permanent epigenetic change.

scientific article published on 11 March 2017

Oral Microbial Species and Virulence Factors Associated with Oral Squamous Cell Carcinoma

scientific article published on 06 November 2020

Ovarian aging and the activation of the primordial follicle reserve in the long-lived Ames dwarf and the short-lived bGH transgenic mice.

scientific article published on 19 October 2016

Ovarian transcriptome associated with reproductive senescence in the long-living Ames dwarf mice.

scientific article

PPARs in Calorie Restricted and Genetically Long-Lived Mice

scientific article published on January 2007

Paraoxonase 1 serum activity in women: the effects of menopause, the C(-107)T polymorphism and food intake

scientific article published on 25 April 2019

Pioglitazone does not improve insulin signaling in mice with GH over-expression

scientific article published on 04 October 2013

Positive fresh frozen section margins as an adverse independent prognostic factor for local recurrence in oral cancer patients

scientific article published on 8 October 2017

Post‐transcriptional regulation of IGF1R by key microRNAs in long–lived mutant mice ⬇️

scientific article published on December 1, 2011

Prediabetes linked to excess glucagon in transgenic mice with pancreatic active AKT1.

scientific article published on 20 October 2015

Primordial follicle activation in the ovary of Ames dwarf mice

scientific article

Primordial follicle reserve, DNA damage and macrophage infiltration in the ovaries of the long-living Ames dwarf mice

scientific article published on 25 January 2020

Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5' tRNA-Val-CAC-2-1 Half

scientific article published on 26 September 2019

RasGrf1: genomic imprinting, VSELs, and aging

scientific article published in July 2011

Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice

scientific article

Renal pro-apoptotic proteins are reduced by growth hormone resistance but not by visceral fat removal.

scientific article published on 11 March 2011

Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice.

scientific article published on 18 May 2015

Self-Assembled STrap for Global Proteomics and Salivary Biomarker Discovery

scientific article published on 21 March 2019

Senolytic combination of Dasatinib and Quercetin alleviates intestinal senescence and inflammation and modulates the gut microbiome in aged mice

scientific article published on 06 January 2021

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

article by Jamie N Justice et al published February 2019 in EBioMedicine

Skeletal muscle RBM3 expression is associated with extended lifespan in Ames dwarf and calorie restricted mice

scientific article published on 29 December 2020

THE GUT MICROBIOME AND AGING

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

THE INFLUENCE OF LIFE-EXTENDING MUTATION AND DIETARY INTERVENTION ON GUT MICROBIOTA

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

THow diet interacts with longevity genes

scientific article published on January 2008

Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

scholarly article

The contribution of visceral fat to improved insulin signaling in Ames dwarf mice.

scientific article

The effect of calorie restriction on insulin signaling in skeletal muscle and adipose tissue of Ames dwarf mice

scientific article

The effect of calorie restriction on the presence of apoptotic ovarian cells in normal wild type mice and low-plasma-IGF-1 Laron dwarf mice

scientific article published on 24 September 2013

The effects of growth hormone (GH) treatment on GH and insulin/IGF-1 signaling in long-lived Ames dwarf mice

scientific article

The enigmatic role of growth hormone in age-related diseases, cognition, and longevity

scientific article published on 04 September 2019

The importance of stem cell engineering in head and neck oncology

scientific article

The interconnections between somatic and ovarian aging in murine models

scientific article published on 10 October 2020

The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs).

scientific article published on 5 January 2012

The role of Ames dwarfism and calorie restriction on gut microbiota

scientific article published on 30 October 2019

The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice

scientific article published on 24 January 2013

The role of transplanted visceral fat from the long-lived growth hormone receptor knockout mice on insulin signaling.

scientific article

Thyroxine modifies the effects of growth hormone in Ames dwarf mice

scientific article published on April 2015

Tissue and serum microRNA profile of oral squamous cell carcinoma patients.

scientific article published on 12 January 2018

Transcriptome profiling reveals divergent expression shifts in brown and white adipose tissue from long-lived GHRKO mice

scientific article

Unpredictable changes of selected miRNA in expression profile of HNSCC.

scientific article published on 12 October 2015

Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice.

scientific article published on 02 September 2012

hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer

scientific article published on 17 May 2017

hTERT gene knockdown enhances response to radio- and chemotherapy in head and neck cancer cell lines through a DNA damage pathway modification

scientific article published on 13 April 2018

hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression

scientific article published on 07 August 2018

miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes

scientific article published on 25 November 2021

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