List of works - Pan-chyr Yang

A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect.

scientific article published on 15 August 2017

A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma

scientific article (publication date: 21 June 2006)

A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis ⬇️

scientific article published on August 19, 2013

A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER)

scientific article

Aberrant p53 expression correlates with expression of vascular endothelial growth factor mRNA and interleukin-8 mRNA and neoangiogenesis in non-small-cell lung cancer

scientific article published on 01 February 2002

Advanced non-small cell lung cancer in patients aged 45 years or younger: outcomes and prognostic factors.

scientific article

Advanced non-small cell lung cancer in the elderly: the impact of age and comorbidities on treatment modalities and patient prognosis.

scientific article published on 22 September 2014

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Antimetabolite pemetrexed primes a favorable tumor microenvironment for immune checkpoint blockade therapy

scientific article published on 01 November 2020

Apoptosis-associated biomarkers in tuberculosis: promising for diagnosis and prognosis prediction.

scientific article

Applications of colour Doppler ultrasound in the diagnosis of chest diseases ⬇️

scientific article published on 01 September 1997

Association Between Parkinson Disease and Risk of Cancer in Taiwan.

scientific article

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

scientific article published on 26 December 2016

Asynchronous thoraco-abdominal motion contributes to decreased 6-minute walk test in patients with COPD.

scientific article

Biomarkers and transcriptome profiling of lung cancer ⬇️

scientific article published on May 1, 2012

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.

scientific article published on 25 March 2014

Changing bacteriology of adult community-acquired lung abscess in Taiwan: Klebsiella pneumoniae versus anaerobes

scientific article published on 25 February 2005

Characterization of large structural genetic mosaicism in human autosome

journal article published in 2015

Circulating miRNA signature for early diagnosis of lung cancer

scientific article

Clinical and microbiological characteristics of urine culture-confirmed genitourinary tuberculosis at medical centers in Taiwan from 1995 to 2007 ⬇️

scientific article published on October 15, 2010

Clinicopathologic characteristics and prognostic significance of EGFR and p53 mutations in surgically resected lung adenocarcinomas ≤2 cm in maximal dimension

scientific article published on 30 April 2014

Clinicopathology and genetic profile of synchronous multiple small adenocarcinomas: implication for surgical treatment of an uncommon lung malignancy.

scientific article published on 19 March 2014

Curcumin Induces EGFR Degradation in Lung Adenocarcinoma and Modulates p38 Activation in Intestine: The Versatile Adjuvant for Gefitinib Therapy ⬇️

scientific article published on August 17, 2011

Diagnosis of tuberculosis by an enzyme-linked immunospot assay for interferon-gamma.

scientific article published on April 2007

Does one size fit all? Building a framework for medical professionalism.

scientific article

Early Detection of Lewis Lung Carcinoma Tumor Control by Irradiation Using Diffusion-Weighted and Dynamic Contrast-Enhanced MRI ⬇️

scientific article published on May 2, 2013

Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition

scientific article published on 13 May 2015

Electrophysiologic changes with incremental exercise in obstructive sleep apnea ⬇️

scientific article published on May 22, 2013

Endobronchial ultrasound-guided transbronchial biopsy of peripheral pulmonary lesions: how many specimens are necessary?

scientific article published on 20 July 2012

Epidemiologic surveillance to detect false-positive Mycobacterium tuberculosis cultures.

scientific article published on 16 June 2012

Evolution of pulmonary pathology in severe acute respiratory syndrome.

scientific article published on February 2005

Extensively drug-resistant Mycobacterium tuberculosis during a trend of decreasing drug resistance from 2000 through 2006 at a Medical Center in Taiwan

scientific article

Factors influencing visibility and diagnostic yield of transbronchial biopsy using endobronchial ultrasound in peripheral pulmonary lesions

scientific article published on 01 August 2009

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

journal article published in 2016

Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimicrobial exposure

scientific article published on 05 April 2007

Gender-Dimorphic Impact of PXR Genotype and Haplotype on Hepatotoxicity During Antituberculosis Treatment

scientific article

Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia

scientific article published on 25 February 2012

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

scientific journal article

Hemothorax in a medical intensive care unit: incidence, comorbidity and prognostic factors.

scientific article published in August 2010

High PD-L1 expression is associated with stage IV disease and poorer overall survival in 186 cases of small cell lung cancers

scientific article

High co-expression of PD-L1 and HIF-1α correlates with tumour necrosis in pulmonary pleomorphic carcinoma

scientific article

Immunofluorescence assay for detection of the nucleocapsid antigen of the severe acute respiratory syndrome (SARS)-associated coronavirus in cells derived from throat wash samples of patients with SARS.

scientific article

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).

scientific article published on 8 January 2015

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

scientific article

Intrapleural minocycline pleurodesis for the treatment of primary spontaneous pneumothorax

scientific article published on July 2014

Invasive infections of Aggregatibacter (Actinobacillus) actinomycetemcomitans

scientific article published on December 2010

Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients.

scientific article published on January 2010

Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients

scientific article

Low serum level of high-density lipoprotein cholesterol is a poor prognostic factor for severe sepsis.

scientific article published in August 2005

Lower gastrointestinal tract tuberculosis: an important but neglected disease

scientific article published on 07 May 2009

MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma.

scientific article published on 2 November 2015

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

scientific article

Management of severe community-acquired septic meningitis in adults: from emergency department to intensive care unit

scientific article published on 01 February 2009

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

scientific article

MicroRNA in lung cancer

scientific article

MicroRNA signature predicts survival and relapse in lung cancer

scientific article published in January 2008

Multi-gene analyses from waste brushing specimens for patients with peripheral lung cancer receiving EBUS-assisted bronchoscopy

scientific article published on 14 October 2013

Mycobacterium tuberculosis inducing disseminated intravascular coagulation

scientific article published on 01 April 2005

Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses

scientific article published on 22 April 2021

Outcome Correlation of Smear-Positivity for Acid-Fast Bacilli at the Fifth Month of Treatment in Non-Multidrug–Resistant TB ⬇️

scientific article published on June 1, 2013

Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme

scientific article published on 04 March 2014

PD-L1 is highly expressed in lung lymphoepithelioma-like carcinoma: A potential rationale for immunotherapy.

scientific article

PKC activation is required by EGF-stimulated Na+-H+exchanger in human pleural mesothelial cells ⬇️

scientific article published on May 1, 1998

Pasteurization is effective against multidrug-resistant bacteria

scientific article published on 01 June 2006

Performance assessment of the Capilia TB assay and the BD ProbeTec ET system for rapid culture confirmation of Mycobacterium tuberculosis.

scientific article published on 18 September 2007

Phosphorylation of LCRMP-1 by GSK3β promotes filopoda formation, migration and invasion abilities in lung cancer cells

scientific article

Pleurodesis for primary spontaneous pneumothorax – Authors' reply ⬇️

scientific article published on July 20, 2013

Population-Based Cohort Study Reveals Distinct Associations Between Female Lung Cancer and Breast Cancer in Taiwan

scientific article published on 01 December 2018

Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection.

scientific article

Programmed cell death-ligand 1 expression in surgically resected stage I pulmonary adenocarcinoma and its correlation with driver mutations and clinical outcomes.

scientific article

Programmed cell death-ligand 1 expression is associated with a favourable immune microenvironment and better overall survival in stage I pulmonary squamous cell carcinoma

scientific article

Relapse of SARS upon tapering corticosteroid

scientific article

Rhabdomyolysis associated with probable SARS.

scientific article published in October 2003

Risk factors for Mycobacterium chelonae-abscessus pulmonary disease persistence and deterioration

scientific article published on 12 November 2011

Risk factors of hepatitis during anti-tuberculous treatment and implications of hepatitis virus load.

scientific article published on 28 April 2011

Severe lymphopenia is associated with elevated plasma interleukin-15 levels and increased mortality during severe sepsis.

scientific article published on June 2015

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

scientific article

Simple aspiration and drainage and intrapleural minocycline pleurodesis versus simple aspiration and drainage for the initial treatment of primary spontaneous pneumothorax: an open-label, parallel-group, prospective, randomised, controlled trial.

scientific article published on 12 March 2013

Specific EGFR mutations predict treatment outcome of stage IIIB/IV patients with chemotherapy-naive non-small-cell lung cancer receiving first-line gefitinib monotherapy

scientific article

Switchable delivery of small interfering RNA using a negatively charged pH-responsive polyethylenimine-based polyelectrolyte complex ⬇️

scientific article published on April 4, 2013

Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras

scientific article published on 04 January 2014

TROP2 is epigenetically inactivated and modulates IGF‐1R signalling in lung adenocarcinoma ⬇️

scientific article published on March 15, 2012

Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy

scientific article published on 05 October 2018

Temporal changes in cytokine/chemokine profiles and pulmonary involvement in severe acute respiratory syndrome

scientific article published on 01 November 2006

Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome

scientific article published in September 2004

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia

scientific article

The EMT regulator slug and lung carcinogenesis ⬇️

scientific article published on June 10, 2011

The Motor Protein KIF14 Inhibits Tumor Growth and Cancer Metastasis in Lung Adenocarcinoma ⬇️

scientific article published on April 23, 2013

The Prognostic Significance of pSTAT1 and CD163 Expressions in Surgically Resected Stage 1 Pulmonary Squamous Cell Carcinomas.

scientific article published on 5 May 2016

The evolution of drug-resistant microorganisms in patients with prolonged mechanical ventilation.

scientific article

The prognostic value of the simplified comorbidity score in the treatment of small cell lung carcinoma

scientific article published in February 2011

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

scientific article published on 12 July 2019

Tumor microenvironment-based screening repurposes drugs targeting cancer stem cells and cancer-associated fibroblasts

scientific article published on 21 September 2021

Turning Diversity Toward Precision

scientific article published on 01 January 2017

Viral load and clinical features in children infected with seasonal influenza B in 2006/2007.

scientific article published on 14 February 2012

α-Catulin Drives Metastasis by Activating ILK and Driving an αvβ3 Integrin Signaling Axis ⬇️

scientific article published on October 9, 2012

List of works by Pan-chyr Yang

A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect.

A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma

A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis ⬇️

A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER)

Aberrant p53 expression correlates with expression of vascular endothelial growth factor mRNA and interleukin-8 mRNA and neoangiogenesis in non-small-cell lung cancer

Advanced non-small cell lung cancer in patients aged 45 years or younger: outcomes and prognostic factors.

Advanced non-small cell lung cancer in the elderly: the impact of age and comorbidities on treatment modalities and patient prognosis.

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Antimetabolite pemetrexed primes a favorable tumor microenvironment for immune checkpoint blockade therapy

Apoptosis-associated biomarkers in tuberculosis: promising for diagnosis and prognosis prediction.

Applications of colour Doppler ultrasound in the diagnosis of chest diseases ⬇️

Association Between Parkinson Disease and Risk of Cancer in Taiwan.

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

Asynchronous thoraco-abdominal motion contributes to decreased 6-minute walk test in patients with COPD.

Biomarkers and transcriptome profiling of lung cancer ⬇️

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.

Changing bacteriology of adult community-acquired lung abscess in Taiwan: Klebsiella pneumoniae versus anaerobes

Characterization of large structural genetic mosaicism in human autosome

Circulating miRNA signature for early diagnosis of lung cancer

Clinical and microbiological characteristics of urine culture-confirmed genitourinary tuberculosis at medical centers in Taiwan from 1995 to 2007 ⬇️

Clinicopathologic characteristics and prognostic significance of EGFR and p53 mutations in surgically resected lung adenocarcinomas ≤2 cm in maximal dimension

Clinicopathology and genetic profile of synchronous multiple small adenocarcinomas: implication for surgical treatment of an uncommon lung malignancy.

Curcumin Induces EGFR Degradation in Lung Adenocarcinoma and Modulates p38 Activation in Intestine: The Versatile Adjuvant for Gefitinib Therapy ⬇️

Diagnosis of tuberculosis by an enzyme-linked immunospot assay for interferon-gamma.

Does one size fit all? Building a framework for medical professionalism.

Early Detection of Lewis Lung Carcinoma Tumor Control by Irradiation Using Diffusion-Weighted and Dynamic Contrast-Enhanced MRI ⬇️

Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition

Electrophysiologic changes with incremental exercise in obstructive sleep apnea ⬇️

Endobronchial ultrasound-guided transbronchial biopsy of peripheral pulmonary lesions: how many specimens are necessary?

Epidemiologic surveillance to detect false-positive Mycobacterium tuberculosis cultures.

Evolution of pulmonary pathology in severe acute respiratory syndrome.

Extensively drug-resistant Mycobacterium tuberculosis during a trend of decreasing drug resistance from 2000 through 2006 at a Medical Center in Taiwan

Factors influencing visibility and diagnostic yield of transbronchial biopsy using endobronchial ultrasound in peripheral pulmonary lesions

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimicrobial exposure

Gender-Dimorphic Impact of PXR Genotype and Haplotype on Hepatotoxicity During Antituberculosis Treatment

Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Hemothorax in a medical intensive care unit: incidence, comorbidity and prognostic factors.

High PD-L1 expression is associated with stage IV disease and poorer overall survival in 186 cases of small cell lung cancers

High co-expression of PD-L1 and HIF-1α correlates with tumour necrosis in pulmonary pleomorphic carcinoma

Immunofluorescence assay for detection of the nucleocapsid antigen of the severe acute respiratory syndrome (SARS)-associated coronavirus in cells derived from throat wash samples of patients with SARS.

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

Intrapleural minocycline pleurodesis for the treatment of primary spontaneous pneumothorax

Invasive infections of Aggregatibacter (Actinobacillus) actinomycetemcomitans

Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients.

Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients

Low serum level of high-density lipoprotein cholesterol is a poor prognostic factor for severe sepsis.

Lower gastrointestinal tract tuberculosis: an important but neglected disease

MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma.

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

Management of severe community-acquired septic meningitis in adults: from emergency department to intensive care unit

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

MicroRNA in lung cancer

MicroRNA signature predicts survival and relapse in lung cancer

Multi-gene analyses from waste brushing specimens for patients with peripheral lung cancer receiving EBUS-assisted bronchoscopy

Mycobacterium tuberculosis inducing disseminated intravascular coagulation

Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses

Outcome Correlation of Smear-Positivity for Acid-Fast Bacilli at the Fifth Month of Treatment in Non-Multidrug–Resistant TB ⬇️

Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme

PD-L1 is highly expressed in lung lymphoepithelioma-like carcinoma: A potential rationale for immunotherapy.

PKC activation is required by EGF-stimulated Na+-H+exchanger in human pleural mesothelial cells ⬇️

Pasteurization is effective against multidrug-resistant bacteria

Performance assessment of the Capilia TB assay and the BD ProbeTec ET system for rapid culture confirmation of Mycobacterium tuberculosis.

Phosphorylation of LCRMP-1 by GSK3β promotes filopoda formation, migration and invasion abilities in lung cancer cells

Pleurodesis for primary spontaneous pneumothorax – Authors' reply ⬇️

Population-Based Cohort Study Reveals Distinct Associations Between Female Lung Cancer and Breast Cancer in Taiwan

Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection.

Programmed cell death-ligand 1 expression in surgically resected stage I pulmonary adenocarcinoma and its correlation with driver mutations and clinical outcomes.

Programmed cell death-ligand 1 expression is associated with a favourable immune microenvironment and better overall survival in stage I pulmonary squamous cell carcinoma

Relapse of SARS upon tapering corticosteroid

Rhabdomyolysis associated with probable SARS.

Risk factors for Mycobacterium chelonae-abscessus pulmonary disease persistence and deterioration

Risk factors of hepatitis during anti-tuberculous treatment and implications of hepatitis virus load.

Severe lymphopenia is associated with elevated plasma interleukin-15 levels and increased mortality during severe sepsis.

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Simple aspiration and drainage and intrapleural minocycline pleurodesis versus simple aspiration and drainage for the initial treatment of primary spontaneous pneumothorax: an open-label, parallel-group, prospective, randomised, controlled trial.