List of works by Tero Ahola

A luciferase-based screening method for inhibitors of alphavirus replication applied to nucleoside analogues

scientific article

Ability of minus strands and modified plus strands to act as templates in Semliki Forest virus RNA replication

scientific article published on 07 March 2016

Alphavirus polymerase and RNA replication

scientific article published on 16 January 2017

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

scientific article published on August 2016

Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells

scientific article

Betulin-derived compounds as inhibitors of alphavirus replication

scientific article published in November 2009

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

scientific article

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.

scientific article published on 18 August 2017

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue.

scientific article published on 15 November 2016

Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis

scientific article (publication date: August 2015)

Correction for Thaa et al., Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

scientific article published on 28 March 2016

Correction: Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

scientific article published on 16 April 2020

Correlative light and electron microscopy enables viral replication studies at the ultrastructural level

scientific article published on 24 April 2015

Design and Validation of Novel Chikungunya Virus Protease Inhibitors

scientific article published on 10 October 2016

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

scientific article published on 2 September 2015

Differential activities of cellular and viral macro domain proteins in binding of ADP-ribose metabolites

scientific article

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

scientific article

Early secretory pathway localization and lack of processing for hepatitis E virus replication protein pORF1.

scientific article published on 19 December 2012

Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants

scientific article

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

scientific article (publication date: 3 March 2009)

Functions of alphavirus nonstructural proteins in RNA replication

scientific article

Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales

scientific article published on 11 May 2016

Identification of Alphavirus Inhibitors by Using Virus-Based Assays and a Chikungunya Replicon Cell Line

scientific article published in 2011

Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis

scientific article published on March 2006

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

scientific article

Inhibitors of virus replication: recent developments and prospects

scientific article

Lentiviral vector-derived shRNAs confer enhanced suppression of Semliki forest virus replication in BHK-21 cells compared to shRNAs expressed from plasmids

scientific article

Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1.

scientific article

Molecular determinants of substrate specificity for Semliki Forest virus nonstructural protease

scientific article published on June 2006

New Phylogenetic Grouping of Positive-Sense RNA Viruses Is Concordant with Replication Complex Morphology

scientific article published on 30 July 2019

Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments

scientific article published on 19 December 2016

Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection

scientific article

Partially Uncleaved Alphavirus Replicase Forms Spherule Structures in the Presence and Absence of RNA Template

scientific article published on 12 July 2017

Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes

scientific article

Polyprotein Processing as a Determinant for in Vitro Activity of Semliki Forest Virus Replicase

scientific article published on 7 October 2017

Purification of highly active alphavirus replication complexes demonstrates altered fractionation of multiple cellular membranes.

scientific article published on 24 January 2018

RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins

scientific article published on 18 November 2015

Regulation of the sequential processing of Semliki Forest virus replicase polyprotein

scientific article published on 12 August 2003

Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication

scientific article

SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication

scientific article published on 17 November 2011

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

scientific article published on 14 June 2019

Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses

scientific article

Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains

scientific article

Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.

scientific article published on 27 March 2013

Template RNA length determines the size of replication complex spherules for Semliki Forest virus

scientific article published on 12 June 2013

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling

scientific article published on 17 August 2016

The C-terminal repeat domains of nsP3 from the Old World alphaviruses bind directly to G3BP

scientific article published on 12 March 2014

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

scientific article (publication date: July 2009)

The RNA Capping Enzyme Domain in Protein A is Essential for Flock House Virus Replication

scholarly article by Tania Quirin published in September 2018

Therapeutics and vaccines against chikungunya virus

scientific article published on April 2015

Treatment of hepatitis C infection: towards eradication of chronic virus

scientific article published in January 2012

Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein

scientific article

Paulina is supported by:

About Paulina

Help