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List of works by Nicholas J. Leeper

"Attack of the Clones": Commonalities Between Cancer and Atherosclerosis

scientific article

18F-Fluorodeoxyglucose-Positron Emission Tomography Imaging Detects Response to Therapeutic Intervention and Plaque Vulnerability in a Murine Model of Advanced Atherosclerotic Disease

scientific article published on 22 October 2020

2020 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions): A Report of the ACC Competenc

scientific article published on 26 November 2020

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

scientific article published on 05 April 2017

A Missing LNC in Vascular Diseases

scientific article published on 01 August 2017

Alternative ankle-brachial index method identifies additional at-risk individuals

scientific article published on 22 May 2013

Androgen Deprivation Therapy and Future Alzheimer's Disease Risk

scientific article

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

scientific article

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

scientific article

Association Between Androgen Deprivation Therapy and Risk of Dementia

scientific article published on 13 October 2016

Association of Blood Pressure Measurements With Peripheral Artery Disease Events

scientific article published on 01 October 2018

Association of lower extremity performance with cardiovascular and all-cause mortality in patients with peripheral artery disease: a systematic review and meta-analysis.

scientific article

Baseline assessment and comparison of arterial anatomy, hyperemic flow, and skeletal muscle perfusion in peripheral artery disease: The Cardiovascular Cell Therapy Research Network "Patients with Intermittent Claudication Injected with ALDH Bright C

scientific article published on 2 October 2016

Bioimpedance and New-Onset Heart Failure: A Longitudinal Study of >500 000 Individuals From the General Population

scientific article published on 29 June 2018

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

scientific article published on 20 July 2016

CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels

scientific article published on 23 November 2015

Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability

scientific article published on 01 December 2021

Clinical and Genetic Determinants of Varicose Veins

scientific article published on 01 December 2018

Clinical and socioeconomic factors associated with unrecognized peripheral artery disease

scientific article published on 28 May 2014

Clinical dilemmas in treating left ventricular thrombus

scientific article published on 17 October 2006

Clinical problem-solving. Fool's Gold

scientific article published in November 2008

Clinical problem-solving. One surprise after another

scientific article

Clinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterol

scientific article published in January 2008

Clonal Smooth Muscle Cell Expansion, Autophagy, and Vascular Integrity in Aortic Aneurysm Disease

scientific article published on 01 June 2019

Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

scientific article published on 15 June 2020

Clustering cancers by shared transcriptional risk reveals novel targets for cancer therapy

publication published on 18 May 2022

Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies-Statement From ATVB Council.

scientific article published on 4 January 2018

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation

scientific article

Correction to: Real-World Predictors of Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients with Chronic Coronary Artery Disease and/or Peripheral Arterial Disease

scientific article published on 01 February 2020

Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis

scientific article published on 17 February 2014

Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis

Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus

scientific article

Effect of physical activity assessment on prognostication for peripheral artery disease and mortality

scientific article published on 31 January 2015

Endogenous regulation of cardiovascular function by apelin-APJ.

scientific article published on 18 September 2009

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).

scientific article published on 16 February 2017

Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease

scientific article published on 6 October 2012

Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

scientific article published on 16 November 2018

Gender does not influence outcomes after iliac angioplasty

scientific article published on 21 January 2002

Genetics of peripheral artery disease

scientific article published on June 2012

Genome-Wide Association Studies Candidate Gene to Dual Modifier of Nonalcoholic Steatohepatitis and Atherosclerosis

scientific article

High-Density Lipoprotein Nanoparticle Imaging in Atherosclerotic Vascular Disease

scientific article published on 27 February 2017

Improved reclassification of mortality risk by assessment of physical activity in patients referred for exercise testing

scientific article

Incentivizing physical activity through activity monitoring interventions in PAD - a pilot study

scientific article published on 05 November 2020

Incidence and Cost of Major Adverse Cardiovascular Events and Major Adverse Limb Events in Patients With Chronic Coronary Artery Disease or Peripheral Artery Disease

scientific article published on 16 March 2019

Influence of age on androgen deprivation therapy-associated Alzheimer's disease

scientific article published on 18 October 2016

Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development

scientific article

Interleukin-6 causes endothelial barrier dysfunction via the protein kinase C pathway.

scientific article

Intradialytic Hypotension and Newly Recognized Peripheral Artery Disease in Patients Receiving Hemodialysis

scientific article published on 03 December 2020

Knockout of the Murine Ortholog to the Human 9p21 Coronary Artery Disease Locus Leads to Smooth Muscle Cell Proliferation, Vascular Calcification, and Advanced Atherosclerosis

scientific article published on 13 April 2020

Leveraging Machine Learning and Artificial Intelligence to Improve Peripheral Artery Disease Detection, Treatment, and Outcomes

scientific article published on 10 June 2021

Loss of CDKN2B Promotes Fibrosis via Increased Fibroblast Differentiation Rather Than Proliferation.

scientific article

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation

scientific article

MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus

scientific article published on 10 January 2011

MicroRNA regulation of vascular smooth muscle function and phenotype: early career committee contribution

scientific article

MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion

scientific article

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions

scientific article

MicroRNA-26a is a novel regulator of vascular smooth muscle cell function

scientific article

Nanoparticle Therapy for Vascular Diseases

scientific article published on 01 April 2019

Network analysis of unstructured EHR data for clinical research

scientific article

Non-coding RNAs: key regulators of smooth muscle cell fate in vascular disease

scientific article

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

scientific article

Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes

scientific article

Predicting Future Cardiovascular Events in Patients With Peripheral Artery Disease Using Electronic Health Record Data

scientific article published on 01 March 2019

Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

scientific article published on 27 January 2020

Proefferocytic Therapy Promotes Transforming Growth Factor-β Signaling and Prevents Aneurysm Formation.

scientific article published in February 2018

Prognostic value of heart rate increase at onset of exercise testing

scientific article published on 22 January 2007

Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population

scientific article

Proton pump inhibitors and vascular function: A prospective cross-over pilot study

scientific article

Rationale and design for PACE: patients with intermittent claudication injected with ALDH bright cells

scientific article

Real-World Predictors of Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients with Chronic Coronary Artery Disease and/or Peripheral Arterial Disease

scientific article published on 08 November 2019

Reply

Reply to R.L. Bowen et al, M. Froehner et al, J.L. Leow et al, and C. Brady et al.

scientific article

Resolvin D1 promotes the targeting and clearance of necroptotic cells

scientific article published on 20 June 2019

Response by Itoga et al to Letter Regarding Article, "Association of Blood Pressure Measurements With Peripheral Arterial Disease Events"

scientific article published on 01 April 2019

Right coronary cameral fistula resulting from surgery of double chamber right ventricle

scientific article published in September 2006

Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden.

scientific article

Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis

scientific article published on 01 May 2019

Statin Intensity or Achieved LDL? Practice-based Evidence for the Evaluation of New Cholesterol Treatment Guidelines

scientific article

Statin Use in Patients With Extremely Low Low-Density Lipoprotein Levels Is Associated With Improved Survival

scientific article published on 30 July 2007

Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells

scientific article

The Intersection of Genome-Wide Association Studies and High-Throughput Small Interfering Ribonucleic Acid Screens Allows for the Identification of Novel Pathways Relevant to Atherosclerosis

scientific article published on 24 April 2017

The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications.

scientific article

The Role of Efferocytosis in Atherosclerosis

scientific article

The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model

scientific article

The effect of angiotensin-converting enzyme inhibitors and statins on the progression of aortic sclerosis and mortality.

scientific article

The effect of preoperative statin therapy on cardiovascular outcomes in patients undergoing infrainguinal vascular surgery

scientific article published on 01 October 2005

The genetic basis of peripheral arterial disease: current knowledge, challenges, and future directions

scientific article published on April 2015

The impact of low-dose anticoagulation therapy on peripheral artery disease: insights from the VOYAGER trial

scientific article published on 01 October 2020

The role of necroptosis in atherosclerotic disease

scientific article

The use of machine learning for the identification of peripheral artery disease and future mortality risk

scientific article published on 3 June 2016

Therapeutic Potential of Modulating MicroRNA in Peripheral Artery Disease

scientific article published in January 2015

Thrombotic Regulation From the Endothelial Cell Perspectives

scientific article published on 01 June 2018

Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.

scientific article published on 04 February 2014

Trends in Rates of Lower Extremity Amputation Among Patients With End-stage Renal Disease Who Receive Dialysis

scientific article published on 01 August 2018

Two decades of progress in vascular medicine.

scientific article

Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse

scientific article

Usefulness of the Addition of Beta-2-Microglobulin, Cystatin C and C-Reactive Protein to an Established Risk Factors Model to Improve Mortality Risk Prediction in Patients Undergoing Coronary Angiography ⬇️

scientific article published on March 15, 2013

Walking impairment questionnaire improves mortality risk prediction models in a high-risk cohort independent of peripheral arterial disease status.

scientific article

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