List of works - Marie-Ève Hamelin

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines

scientific article published on 17 December 2014

Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines

scientific article published on 27 August 2014

Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children

scientific article

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada

scientific article

Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children.

scientific article published on 2 May 2012

Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance

scientific article (publication date: 2012)

Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein

scientific article published on February 2005

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform.

scientific article published on 12 May 2008

Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model

scientific article published on 24 March 2015

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection

scientific article

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

scientific article published in March 2010

Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice

scientific article published on 21 December 2011

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

scientific article published on 11 November 2009

Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus

scientific article published on December 2007

Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus

scientific article

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

scientific article

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade.

scientific article published on 4 September 2013

Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections.

scientific article

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

scientific article published on 09 April 2019

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.

scientific article published on 11 May 2006

Human metapneumovirus viral load is an important risk factor for disease severity in young children

scientific article published on 12 March 2014

Human metapneumovirus.

scientific article

Human metapneumovirus: a new player among respiratory viruses

scientific article published on 15 March 2004

Human metapneumovirus: a ubiquitous and long-standing respiratory pathogen

scientific article

Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus

scientific article

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets

scientific article

Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia

scientific article

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

scientific article published on 7 April 2015

Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice

scientific article published on 16 March 2011

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model

scientific article

Molecular and antigenic evolution of human influenza A/H3N2 viruses in Quebec, Canada, 2009-2011.

scientific article published on 28 October 2011

Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010.

scientific article published in January 2012

Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia

scientific article

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

scientific article

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

scientific article published on July 2005

Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission.

scientific article

Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model.

scientific article

Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections

scientific article published on 4 November 2017

Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk

scientific article

Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets

scientific article

Seroconversion to seasonal influenza viruses after A(H1N1)pdm09 virus infection, Quebec, Canada

scientific article

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

scientific article

Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice

scientific article published on 11 April 2013

List of works by Marie-Ève Hamelin

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines

Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines

Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada

Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children.

Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance

Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform.

Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus

Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade.

Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections.

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.

Human metapneumovirus viral load is an important risk factor for disease severity in young children

Human metapneumovirus.

Human metapneumovirus: a new player among respiratory viruses

Human metapneumovirus: a ubiquitous and long-standing respiratory pathogen

Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets

Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model

Molecular and antigenic evolution of human influenza A/H3N2 viruses in Quebec, Canada, 2009-2011.

Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010.

Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission.

Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model.

Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections

Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk

Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets

Seroconversion to seasonal influenza viruses after A(H1N1)pdm09 virus infection, Quebec, Canada

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice