List of works - Diane Nugent

A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia ⬇️

scientific article published on April 18, 2011

Associations of quality of life, pain, and self-reported arthritis with age, employment, bleed rate, and utilization of hemophilia treatment center and health care provider services: results in adults with hemophilia in the HERO study

scientific article

Conditional knockout of integrin α2β1 in murine megakaryocytes leads to reduced mean platelet volume

scientific article

Consensus Paper-ICIS Expert Meeting Basel 2009 treatment milestones in immune thrombocytopenia

scientific article

Effects of hematopoietic stem cell transplantation on acyl-CoA oxidase deficiency: a sibling comparison study.

scientific article

Enhanced binding of poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 promoter via an extended cytosine-adenosine repeat

scientific article

FondaKIDS: a prospective pharmacokinetic and safety study of fondaparinux in children between 1 and 18 years of age.

scientific article

Genetic variants that affect platelet function ⬇️

scientific article published on September 1, 2012

Identification of patients with RAG mutations previously diagnosed with common variable immunodeficiency disorders

scientific article published on 17 December 2014

Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro

scientific article

Immune thrombocytopenic purpura of childhood

scientific article

Influence of platelet collagen receptor polymorphisms on risk for arterial thrombosis

scientific article

Late effects in hematopoietic cell transplant recipients with acquired severe aplastic anemia: a report from the late effects working committee of the center for international blood and marrow transplant research

scientific article

Mild B-cell lymphocytosis in patients with a CARD11 C49Y mutation

scientific article

Monozygotic Twin Pair Showing Discordant Phenotype for X-linked Thrombocytopenia and Wiskott–Aldrich Syndrome: a Role for Epigenetics? ⬇️

scientific article published on June 28, 2011

Pathogenesis of chronic immune thrombocytopenia: increased platelet destruction and/or decreased platelet production

scientific article

Pediatric stroke and methylenetetrahydrofolate reductase polymorphisms: an examination of C677T and A1298C mutations

scientific article

Platelet adhesion to decorin but not collagen I correlates with the integrin 2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system ⬇️

scientific article published on December 1, 2011

Platelet genomics: the role of platelet size and number in health and disease

scientific article published on 29 December 2016

Promising biomarkers for the prediction of catheter-related venous thromboembolism in hospitalized children: An exploratory study

scientific article published on 21 June 2019

Prophylaxis in rare coagulation disorders -- factor XIII deficiency

scientific article

Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia

scientific article

Rare factor deficiencies

scientific article published on September 2012

Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia

scientific article

Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency

scientific article

Single dose of anti-D immune globulin at 75 microg/kg is as effective as intravenous immune globulin at rapidly raising the platelet count in newly diagnosed immune thrombocytopenic purpura in children

scientific article

Spotlight on romiplostim in the treatment of children with chronic immune thrombocytopenia: design, development, and potential place in therapy

scientific article

Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia

scientific article

Successful treatment of post-transplant thrombocytopenia with romiplostim in a pediatric patient with X-linked chronic granulomatous disease

scientific article

Sustained engraftment post bone marrow transplant despite anti-platelet antibodies in Glanzmann thrombasthenia

scientific article

The effect of antiplatelet autoantibodies on megakaryocytopoiesis

scientific article

The genetics of normal platelet reactivity

scientific article

The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis.

scientific article

The low-frequency isoform of platelet glycoprotein VIb attenuates ligand-mediated signal transduction but not receptor expression or ligand binding.

scientific article published on 22 May 2009

Thrombopoietic agents for the treatment of persistent and chronic immune thrombocytopenia in children

scientific article

Tissue factor inflammatory response regulated by promoter genotype and p38 MAPK in neonatal vs. adult microvascular endothelial cells

scientific article published on 03 January 2014

Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2

scientific article

Unrelated Hematopoietic Cell Transplantation in a Patient with Combined Immunodeficiency with Granulomatous Disease and Autoimmunity Secondary to RAG Deficiency.

scientific article published on 18 August 2016

Viruses, anti-viral therapy, and viral vaccines in children with immune thrombocytopenia

scientific article

Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments

scientific article

List of works by Diane Nugent

A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia ⬇️

Associations of quality of life, pain, and self-reported arthritis with age, employment, bleed rate, and utilization of hemophilia treatment center and health care provider services: results in adults with hemophilia in the HERO study

Conditional knockout of integrin α2β1 in murine megakaryocytes leads to reduced mean platelet volume

Consensus Paper-ICIS Expert Meeting Basel 2009 treatment milestones in immune thrombocytopenia

Effects of hematopoietic stem cell transplantation on acyl-CoA oxidase deficiency: a sibling comparison study.

Enhanced binding of poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 promoter via an extended cytosine-adenosine repeat

FondaKIDS: a prospective pharmacokinetic and safety study of fondaparinux in children between 1 and 18 years of age.

Genetic variants that affect platelet function ⬇️

Identification of patients with RAG mutations previously diagnosed with common variable immunodeficiency disorders

Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro

Immune thrombocytopenic purpura of childhood

Influence of platelet collagen receptor polymorphisms on risk for arterial thrombosis

Late effects in hematopoietic cell transplant recipients with acquired severe aplastic anemia: a report from the late effects working committee of the center for international blood and marrow transplant research

Mild B-cell lymphocytosis in patients with a CARD11 C49Y mutation

Monozygotic Twin Pair Showing Discordant Phenotype for X-linked Thrombocytopenia and Wiskott–Aldrich Syndrome: a Role for Epigenetics? ⬇️

Pathogenesis of chronic immune thrombocytopenia: increased platelet destruction and/or decreased platelet production

Pediatric stroke and methylenetetrahydrofolate reductase polymorphisms: an examination of C677T and A1298C mutations

Platelet adhesion to decorin but not collagen I correlates with the integrin 2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system ⬇️

Platelet genomics: the role of platelet size and number in health and disease

Promising biomarkers for the prediction of catheter-related venous thromboembolism in hospitalized children: An exploratory study

Prophylaxis in rare coagulation disorders -- factor XIII deficiency

Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia

Rare factor deficiencies

Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia

Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency

Single dose of anti-D immune globulin at 75 microg/kg is as effective as intravenous immune globulin at rapidly raising the platelet count in newly diagnosed immune thrombocytopenic purpura in children

Spotlight on romiplostim in the treatment of children with chronic immune thrombocytopenia: design, development, and potential place in therapy

Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia

Successful treatment of post-transplant thrombocytopenia with romiplostim in a pediatric patient with X-linked chronic granulomatous disease

Sustained engraftment post bone marrow transplant despite anti-platelet antibodies in Glanzmann thrombasthenia

The effect of antiplatelet autoantibodies on megakaryocytopoiesis

The genetics of normal platelet reactivity

The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis.

The low-frequency isoform of platelet glycoprotein VIb attenuates ligand-mediated signal transduction but not receptor expression or ligand binding.

Thrombopoietic agents for the treatment of persistent and chronic immune thrombocytopenia in children

Tissue factor inflammatory response regulated by promoter genotype and p38 MAPK in neonatal vs. adult microvascular endothelial cells

Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2

Unrelated Hematopoietic Cell Transplantation in a Patient with Combined Immunodeficiency with Granulomatous Disease and Autoimmunity Secondary to RAG Deficiency.

Viruses, anti-viral therapy, and viral vaccines in children with immune thrombocytopenia

Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments