Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Vadim A Makarov

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

6,11-Dioxobenzo[f]pyrido[1,2-a]indoles kill Mycobacterium tuberculosis by targeting iron-sulfur protein Rv0338c (IspQ) a putative redox sensor

scientific article published on 15 September 2020

A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.

scientific article published on 16 February 2018

A proof-of-concept study for the efficacy of dispirotripiperazine PDSTP in a rabbit model of herpes simplex epithelial keratitis

scientific article published in 2022

A rapid method for estimation of the efficacy of potential antimicrobials in humans and animals by agar diffusion assay

scientific article published on 23 November 2018

Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.

scientific article

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis

scientific article published on October 2010

Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance

scientific article

Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones

scientific article

Design and Synthesis of Pyrano[3,2-<i>b</i>]indolones Showing Antimycobacterial Activity

scientific article published on 22 December 2020

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

scientific article published on 31 May 2019

Development of Machine Learning Models and the Discovery of a New Antiviral Compound against Yellow Fever Virus

scientific article published on 23 August 2021

Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria

scholarly article by Raphael Sommer et al published 5 October 2018 in ACS Chemical Biology

Fluorescent benzothiazinone analogs efficiently and selectively label DprE1 in mycobacteria and actinobacteria

In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis

scientific article

Mechanism of action of 5-nitrothiophenes against Mycobacterium tuberculosis

scientific article published on 18 February 2014

Multiple approaches to repurposing drugs for neuroblastoma

scientific article published in November 2022

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

scientific article published on 18 August 2017

New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis

scientific article published on 17 May 2017

New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis

scientific article published on 23 January 2020

Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169)

scientific article published on 24 October 2018

Qsar Analysis of [(Biphenyloxy)Propyl]Isoxazoles: Agents Against Coxsackievirus B3 ⬇️

scientific article published on January 1, 2011

Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis

scientific article

Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis

scholarly article by Jérémie Piton et al published October 2018 in Antimicrobial Agents and Chemotherapy

Structure-based drug design and characterization of sulfonyl-piperazine benzothiazinone inhibitors of DprE1 fromMycobacterium tuberculosis

scholarly article published 10 April 2018

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

scientific article published on 18 May 2015

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

scientific article published on 18 June 2015

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

scientific article

Paulina is supported by:

About Paulina

Help