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List of works by Martyn P Mahaut-Smith

A Role for Platelet TRPC Channels in the Ca 2+ Response That Induces Procoagulant Activity ⬇️

scientific article published on June 25, 2013

A major interspecies difference in the ionic selectivity of megakaryocyte Ca2+-activated channels sensitive to the TMEM16F inhibitor CaCCinh-A01

scientific article published on 22 April 2019

A major role for P2X1 receptors in the early collagen-evoked intracellular Ca2+ responses of human platelets

scientific article published on 01 July 2005

A role for membrane potential in regulating GPCRs?

scientific article published on 11 July 2008

A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors

scientific article

Ca2+ influx through P2X1 receptors amplifies P2Y1 receptor-evoked Ca2+ signaling and ADP-evoked platelet aggregation.

scientific article

Ca2+ waves coordinate purinergic receptor-evoked integrin activation and polarization

scientific article published on 21 January 2020

Calcium Signalling through Ligand-Gated Ion Channels such as P2X1 Receptors in the Platelet and other Non-Excitable Cells.

scientific article published on January 2016

Connexin40 regulates platelet function

scientific article published on January 2013

Detachment of surface membrane invagination systems by cationic amphiphilic drugs

scientific article (publication date: 2016)

Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions.

scientific article published on 24 May 2017

Differential sensitivity of human platelet P2X1 and P2Y1 receptors to disruption of lipid rafts.

scientific article published on 9 March 2006

Direct voltage control of endogenous lysophosphatidic acid G-protein-coupled receptors in Xenopus oocytes.

scientific article published on 29 March 2010

Direct voltage control of signaling via P2Y1 and other Galphaq-coupled receptors

scientific article published on 4 November 2004

Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.

scientific article

Effects of enhanced P2X1 receptor Ca2+ influx on functional responses in human platelets

scientific article published in September 2002

Emerging roles for P2X1 receptors in platelet activation

scientific article published on May 2004

Evidence for shear-mediated Ca2+ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line.

scientific article

Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+ influx pathway of platelets and megakaryocytes

scientific article

Extracellular Ca2+ modulates ADP‐evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation ⬇️

scientific article published on February 20, 2011

FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists

scientific article

Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.

scientific article

Heat Shock Protein 90 Inhibitors Reduce Trafficking of ATP-gated P2X1 Receptors and Human Platelet Responsiveness ⬇️

scientific article published on July 31, 2012

Kv1.3 is the exclusive voltage-gated K+ channel of platelets and megakaryocytes: roles in membrane potential, Ca2+ signalling and platelet count

scientific article

Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis

scientific article

Measurement and manipulation of intracellular Ca2+ in single platelets and megakaryocytes

scientific article

Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte

scientific article published on 20 July 2006

Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6.

scientific article published on 18 June 2003

P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic window

scientific article published on January 2009

P2X1 Receptors Amplify FcγRIIa-Induced Ca2+ Increases and Functional Responses in Human Platelets.

scientific article published on 29 January 2018

P2X1 receptor mobility and trafficking; regulation by receptor insertion and activation

scientific article published on 2 April 2010

Patch-clamp recordings of electrophysiological events in the platelet and megakaryocyte

scientific article published on 01 January 2004

Platelet Ca2+ responses coupled to glycoprotein VI and Toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca2+ stores ⬇️

scientific article published on January 6, 2012

Potentiation of P2Y receptors by physiological elevations of extracellular K+ via a mechanism independent of Ca2+ influx.

scientific article published on 14 February 2005

Properties of the demarcation membrane system in living rat megakaryocytes.

scientific article

Purification of Native Bone Marrow Megakaryocytes for Studies of Gene Expression ⬇️

scientific article published on January 1, 2012

Regulation of Pannexin-1 channel activity.

scientific article published on June 2015

Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+ mobilization in the rat megakaryocyte

scientific article published on 28 November 2003

Temperature dependence of human ether-a-go-go-related gene K+ currents

scientific article published in February 2006

The P2X1 receptor and platelet function ⬇️

scientific article published on March 22, 2011

The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range

scientific article

Transcriptomic analysis of the ion channelome of human platelets and megakaryocytic cell lines.

scientific article published on 9 June 2016

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