List of works by Jun Koseki

A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones

scientific article published on 25 September 2018

A Hydrogen Peroxide Activatable Gemcitabine Prodrug for the Selective Treatment of Pancreatic Ductal Adenocarcinoma

scientific article published on 04 July 2019

A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells

scientific article published on 11 February 2016

A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients

scientific article published on 20 November 2015

Association of iron metabolic enzyme hepcidin expression levels with the prognosis of patients with pancreatic cancer.

scientific article published on 26 March 2018

BRAF V600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells

scientific article

CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure

scientific article published on 16 October 2019

Cancer stem cells of the digestive system

scientific article

Cancer stem cells: The potential of carbon ion beam radiation and new radiosensitizers (Review).

scientific article published on September 2015

Carbon ion beam radioresistant rodent cells are sensitized to trifluorothymidine exposure.

scientific article published on 21 June 2018

Cell-free culture conditioned medium elicits pancreatic β cell lineage-specific epigenetic reprogramming in mice.

scientific article published on 21 June 2018

Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer

scientific article published on 29 July 2016

Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis.

scientific article published on 16 September 2014

Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells

scientific article published on 17 January 2018

Cyclin G2: A novel independent prognostic marker in pancreatic cancer

scientific article published on 2 September 2015

Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells

scientific article published on 14 February 2019

Distinct methylation levels of mature microRNAs in gastrointestinal cancers

scientific article published on 29 August 2019

Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2

Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming.

scientific article published on 15 July 2015

Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis

scientific article published on 10 January 2018

Fetal hepatocyte-derived culture medium elicits adipocyte differentiation to bile duct cell lineages in a mouse model.

scientific article

High expression of ADAMTS5 is a potent marker for lymphatic invasion and lymph node metastasis in colorectal cancer

scientific article published on 21 November 2016

Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer

scientific article published on 7 December 2017

Identification of chemoradiation-resistant osteosarcoma stem cells using an imaging system for proteasome activity

scientific article published on 24 September 2014

Low expression of the GOPC is a poor prognostic marker in colorectal cancer

scientific article published on 24 August 2017

Mathematical analysis predicts imbalanced IDH1/2 expression associates with 2-HG-inactivating β-oxygenation pathway in colorectal cancer

scientific article published on 12 January 2015

Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.

scientific article published on 07 December 2016

MicroRNA miR-374, a potential radiosensitizer for carbon ion beam radiotherapy

scientific article published on 22 September 2016

MicroRNA profiles involved in trifluridine resistance

scientific article published on 23 May 2017

MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells

scientific article published on 13 May 2015

Mitochondrial pyruvate carrier 1 expression controls cancer epithelial-mesenchymal transition and radioresistance

scientific article published on 01 April 2019

Mitochondrial pyruvate carrier modulates the epithelial-mesenchymal transition in cholangiocarcinoma

scientific article published on 20 December 2017

Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer

scientific article published on 21 December 2017

Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer

scientific article

Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells

scientific article published on 08 August 2018

Polyamine flux suppresses histone lysine demethylases and enhances expression in cancer stem cells

scientific article published on 13 November 2018

Prognostic Impact of Peritumoral IL-17-Positive Cells and IL-17 Axis in Patients with Intrahepatic Cholangiocarcinoma

scientific article published on 31 July 2015

Pyruvate kinase M2, but not M1, allele maintains immature metabolic states of murine embryonic stem cells

scientific article published on 09 March 2015

Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition.

scientific article

Susceptibility of pancreatic cancer stem cells to reprogramming

scientific article

The combination of the expression of hexokinase 2 and pyruvate kinase M2 is a prognostic marker in patients with pancreatic cancer

scientific article published on 22 January 2015

The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells

scientific article published on 7 December 2017

The importance of mitochondrial folate enzymes in human colorectal cancer.

scientific article published on 22 November 2016

The mitochondrial one-carbon metabolic pathway is associated with patient survival in pancreatic cancer

Theoretical analyses and experimental validation of the effects caused by the fluorinated substituent modification of DNA

scientific article published on 24 January 2020

Visualization and characterization of cancer stem-like cells in cervical cancer

scientific article published on 24 September 2014

[Therapeutic Implication Targeting for Cancer Stem Cells].

scientific article published in September 2015

c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer.

scientific article published on 24 May 2018