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Authors whose works are in public domain in at least one jurisdiction

List of works by James G McNally

A benchmark for chromatin binding measurements in live cells.

scientific article

A flow cytometric method to detect protein-protein interaction in living cells by directly visualizing donor fluorophore quenching during CFP-->YFP fluorescence resonance energy transfer (FRET).

scientific article published in October 2003

Analysis of binding at a single spatially localized cluster of binding sites by fluorescence recovery after photobleaching.

scientific article

Analysis of binding reactions by fluorescence recovery after photobleaching

scientific article

Analysis of cholesterol export from endo-lysosomes by Niemann Pick C2 protein using combined fluorescence and X-ray microscopy

Anti-angiogenic activity of human endostatin is HIF-1-independent in vitro and sensitive to timing of treatment in a human saphenous vein assay.

scientific article

Assembly and function of the actin cytoskeleton of yeast: relationships between cables and patches.

scientific article

Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription

scientific article

CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites

scientific article

Capping protein levels influence actin assembly and cell motility in dictyostelium

scientific article (publication date: May 1995)

Cells Undergo Major Changes in the Quantity of Cytoplasmic Organelles after Uptake of Gold Nanoparticles with Biologically Relevant Surface Coatings

scientific article published on 28 January 2020

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

scientific article

Changes in nucleoid morphology and origin localization upon inhibition or alteration of the actin homolog, MreB, of Vibrio cholerae.

scientific article

Co-expressed genes prepositioned in spatial neighborhoods stochastically associate with SC35 speckles and RNA polymerase II factories.

scientific article

Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter.

scientific article

Convergence of chromatin binding estimates in live cells.

scientific article

Crm1 is a mitotic effector of Ran-GTP in somatic cells

scientific article

Cross-validating FRAP and FCS to quantify the impact of photobleaching on in vivo binding estimates ⬇️

scientific article published on November 3, 2010

Design and In Vivo Immunogenicity of a Polyvalent Vaccine Based on SIVmac Regulatory Genes

article

Detecting protein-protein interactions with CFP-YFP FRET by acceptor photobleaching

scientific article

Direct measurement of association and dissociation rates of DNA binding in live cells by fluorescence correlation spectroscopy.

scientific article published on July 2009

Dissecting the binding mechanism of the linker histone in live cells: an integrated FRAP analysis. ⬇️

scientific article

Dynamic behavior of transcription factors on a natural promoter in living cells

scientific article

Dynamic effect of bortezomib on nuclear factor-kappaB activity and gene expression in tumor cells.

scientific article

Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeller

scientific article

Dynamics of gene targeting and chromatin remodelling by nuclear receptors

scientific article published in January 2000

E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

scientific article published on April 2004

Enhanced effector function of CD8(+) T cells from healthy controls and HIV-infected patients occurs through thrombin activation of protease-activated receptor 1.

scientific article

Evidence for a common mode of transcription factor interaction with chromatin as revealed by improved quantitative fluorescence recovery after photobleaching.

scientific article published on 16 January 2008

FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know?

scientific article

Flow cytometric measurement of fluorescence (Förster) resonance energy transfer from cyan fluorescent protein to yellow fluorescent protein using single-laser excitation at 458 nm.

scientific article

Fluorescence recovery after photobleaching (FRAP) methods for visualizing protein dynamics in living mammalian cell nuclei

scientific article published in January 2004

Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser.

scientific article

Fractal geometry in the nucleus

scientific article

Generic features of tertiary chromatin structure as detected in natural chromosomes

scientific article published in November 2004

Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability.

scientific article

Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function

scientific article published on 11 April 2012

Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload

scientific article

Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation

scientific article

Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation

scientific article published in February 2004

Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation.

scientific article

Intracellular delivery of acetyl-histone peptides inhibits native bromodomain-chromatin interactions and impairs mitotic progression.

scientific article

Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation

scientific article

Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter

scientific article

Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes ⬇️

scientific article published on October 3, 2013

Minimizing the impact of photoswitching of fluorescent proteins on FRAP analysis

scientific article published on 3 April 2012

Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques

scientific article published on 10 October 2003

Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription

scientific article

Monitoring dynamic binding of chromatin proteins in vivo by fluorescence correlation spectroscopy and temporal image correlation spectroscopy.

scientific article

Monitoring dynamic binding of chromatin proteins in vivo by fluorescence recovery after photobleaching.

scientific article published in January 2012

Monitoring dynamic binding of chromatin proteins in vivo by single-molecule tracking

scientific article published in January 2013

Novel functional dissection of the localization-specific roles of budding yeast polo kinase Cdc5p.

scientific article

Organization of chromatin and histone modifications at a transcription site.

scientific article

Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages.

scientific article

Photoswitching-free FRAP analysis with a genetically encoded fluorescent tag

scientific article (publication date: 2014)

Potential Roles for Ubiquitin and the Proteasome during Ribosome Biogenesis

Potential roles for ubiquitin and the proteasome during ribosome biogenesis

scientific article

Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton.

scientific article

Quantifying transcription factor kinetics: at work or at play?

scientific article published on 11 September 2013

Quantitation of GFP-fusion proteins in single living cells

scientific article

Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

scientific article published on April 2004

Regulation of RNA polymerase II activation by histone acetylation in single living cells.

scientific article published on 21 September 2014

Regulation of TATA-binding protein dynamics in living yeast cells

scientific article

Requirement for the budding yeast polo kinase Cdc5 in proper microtubule growth and dynamics

scientific article

Role of H1 phosphorylation in rapid GR exchange and function at the MMTV promoter

scientific article published on 17 November 2005

SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles

scientific article

Single molecule tracking of Ace1p in Saccharomyces cerevisiae defines a characteristic residence time for non-specific interactions of transcription factors with chromatin

scientific article

Single-Molecule Analysis Reveals Linked Cycles of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast

scientific article published on 11 October 2018

Single-molecule analysis of transcription factor binding at transcription sites in live cells

scientific article

Smallpox vaccine safety is dependent on T cells and not B cells

scientific article

Stress-dependent proteolytic processing of the actin assembly protein Lsb1 modulates a yeast prion

scientific article

TLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signaling

scientific article

TcR-induced regulated secretion leads to surface expression of CTLA-4 in CD4+CD25+ T cells

scientific article published on 04 April 2008

The arylstibonic acid compound NSC13746 disrupts B-ZIP binding to DNA in living cells.

scientific article published on April 2010

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

scientific article

The interaction of NSBP1/HMGN5 with nucleosomes in euchromatin counteracts linker histone-mediated chromatin compaction and modulates transcription.

scientific article published on September 2009

Three-dimensional cellular ultrastructure resolved by X-ray microscopy.

scientific article

Three-dimensional imaging by deconvolution microscopy.

scientific article

Towards an atlas of mammalian cell ultrastructure by cryo soft X-ray tomography.

scientific article

Transcription dynamics

scientific article published on September 2009

Transcription factories

scientific article

iLAP: a workflow-driven software for experimental protocol development, data acquisition and analysis

scientific article

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