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List of works by Yitzhak Pilpel

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

scientific article

A broad analysis of splicing regulation in yeast using a large library of synthetic introns

scientific article published on 27 September 2021

A catalog of stability-associated sequence elements in 3' UTRs of yeast mRNAs

scientific article

A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool

scientific article (publication date: 2014)

A dual program for translation regulation in cellular proliferation and differentiation

scientific article published on September 2014

A mathematical model for adaptive prediction of environmental changes by microorganisms.

scientific article

A relay race on the evolutionary adaptation spectrum

scientific article

A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis

scientific article published on 01 July 2019

Adaptive prediction of environmental changes by microorganisms.

scientific article

An evolutionarily conserved mechanism for controlling the efficiency of protein translation

scientific article

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

scientific article published on 13 January 2012

Biological causal links on physiological and evolutionary time scales

scientific article published on 26 April 2016

Can molecular motors drive distance measurements in injured neurons?

scientific article

Chromosomal duplication is a transient evolutionary solution to stress.

scientific article

Codon usage of highly expressed genes affects proteome-wide translation efficiency

scientific article published on 07 May 2018

Comprehensive quantitative analyses of the effects of promoter sequence elements on mRNA transcription

scientific article

Computational identification of transcription factor binding sites via a transcription-factor-centric clustering (TFCC) algorithm

scientific article published in April 2002

Correction: Functional Characterization of Variations on Regulatory Motifs.

scientific article published on 2 June 2008

Correction: Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates

scientific article published on 19 January 2017

Correction: Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II.

scientific article published on 26 September 2011

Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate.

scientific article

CpG Islands as a putative source for animal miRNAs: evolutionary and functional implications

scientific article published on 22 November 2010

Determinants of translation efficiency and accuracy ⬇️

scientific article

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

scientific article published on 13 December 2018

Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks

scientific article

Dissecting splicing decisions and cell-to-cell variability with designed sequence libraries

scientific article published on 08 October 2019

Does cancer strive to minimize the cost of gene expression?

scientific article published on 15 June 2018

Dynamic changes in translational efficiency are deduced from codon usage of the transcriptome ⬇️

scientific article published on August 31, 2012

EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors

scientific article

Evolthon: A community endeavor to evolve lab evolution

scientific article published on 29 March 2019

Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms

scientific article published on 23 August 2019

Experimental Evolution of Bacillus subtilis Reveals the Evolutionary Dynamics of Horizontal Gene Transfer and Suggests Adaptive and Neutral Effects

scientific article published on 26 August 2020

Functional characterization of variations on regulatory motifs

scientific article

Gene Architectures that Minimize Cost of Gene Expression

scientific article

Genetic redundancy: new tricks for old genes

scientific article published in February 2009

Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in Saccharomyces cerevisiae

scientific article published on November 2002

Global and local architecture of the mammalian microRNA-transcription factor regulatory network.

scientific article

High-throughput interrogation of programmed ribosomal frameshifting in human cells

scientific article published on 14 November 2018

High-throughput interrogation of programmed ribosomal frameshifting in human cells

scientific article published on 16 June 2020

Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest

scientific article published on 24 December 2020

Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects

scientific article

Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates

scientific journal article

Nucleotide variation of regulatory motifs may lead to distinct expression patterns

scientific article published in July 2007

Preferential protection of protein interaction network hubs in yeast: evolved functionality of genetic redundancy

scholarly article

Promoting human promoters

scientific article published on 6 June 2006

RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system.

scientific article published in September 2017

RNA editing in bacteria: occurrence, regulation and significance

scientific article published on 02 August 2018

Regulatory mechanisms and networks couple the different phases of gene expression ⬇️

scientific article published on July 15, 2011

Repertoires of tRNAs: The Couplers of Genomics and Proteomics

scientific article published on 20 August 2018

Repression of transposable-elements - a microRNA anti-cancer defense mechanism?

scientific article published on 22 April 2010

Signaling to transcription networks in the neuronal retrograde injury response.

scientific article published on 13 July 2010

Specialization versus adaptation: two strategies employed by cyanophages to enhance their translation efficiencies ⬇️

scientific article published on April 5, 2011

Subcellular transcriptomics-dissection of the mRNA composition in the axonal compartment of sensory neurons

scientific article published on 18 November 2013

Systematic Detection of Amino Acid Substitutions in Proteomes Reveals Mechanistic Basis of Ribosome Errors and Selection for Translation Fidelity

scientific article published on 25 July 2019

The Lamarckian chicken and the Darwinian egg.

scientific article published on July 2015

The Molecular and Functional Foundations of Conducive Somatic Cell Reprogramming to Ground State Pluripotency

The majority of endogenous microRNA targets within Alu elements avoid the microRNA machinery

scientific article published on 29 January 2013

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation.

scientific article published on 18 October 2005

Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes

scientific article

Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II ⬇️

scientific article published on September 8, 2011

Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation

scientific article published on 14 October 2008

Widespread promoter-mediated coordination of transcription and mRNA degradation ⬇️

scientific article published on December 13, 2012

microRNAs and Alu elements in the p53-Mdm2-Mdm4 regulatory network.

scientific article

p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.

scientific article

tRNA genes rapidly change in evolution to meet novel translational demands.

scientific article published on 20 December 2013

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