List of works - Walter J Lukiw

A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States ⬇️

scientific article published on April 10, 2012

A microRNA cluster (let-7c, miRNA-99a, miRNA-125b, miRNA-155 and miRNA-802) encoded at chr21q21.1-chr21q21.3 and the phenotypic diversity of Down's syndrome (DS; trisomy 21)

scientific article published on September 2017

A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

scientific article

Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells ⬇️

scientific article published on October 6, 2010

Addressing Alzheimer's Disease (AD) Neuropathology Using Anti-microRNA (AM) Strategies

scientific article published on 10 June 2019

Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer's Disease

scientific article published on 16 November 2019

Aluminum in Neurological and Neurodegenerative Disease

scientific article published on 31 January 2019

Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism

scientific article

Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer's disease (AD).

scientific article

Analysis of RNA from Alzheimer's Disease Post-mortem Brain Tissues

scientific article

Apolipoprotein E epsilon4 offers protection against age-related macular degeneration

scientific article published on 4 December 2006

Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD)

scientific article

Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD) ⬇️

scientific article published on March 20, 2012

Comparing miRNAs and viroids; highly conserved molecular mechanisms for the transmission of genetic information

scientific article (publication date: 2014)

DNA Repair in Photoreceptor Survival ⬇️

scientific article published on October 1, 2003

Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer's Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7)

scientific article published on 5 December 2016

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders

scientific article published on 11 December 2017

Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.

scientific article

Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models

scientific article

Evolution and Complexity of Micro RNA in the Human Brain ⬇️

scientific article published on September 3, 2012

Evolution of microRNA (miRNA) Structure and Function in Plants and Animals: Relevance to Aging and Disease

scientific article

Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer's Disease

scientific article published on 30 April 2020

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

scientific article

HSV-1 latent rabbits shed viral DNA into their saliva

scientific article

High-field 19.6T 27Al solid-state MAS NMR of in vitro aluminated brain tissue

scientific article

Hypoxia signaling to genes: significance in Alzheimer's disease

scientific article

Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells

scientific article

Inhibition of Poly(ADP-ribose) Polymerase-1 Enhances Gene Expression of Selected Sirtuins and APP Cleaving Enzymes in Amyloid Beta Cytotoxicity

scientific article published on 12 July 2017

Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children

scientific article

Mercury from chlor-alkali plants: measured concentrations in food product sugar

scientific article

Metal-sulfate induced generation of ROS in human brain cells: detection using an isomeric mixture of 5- and 6-carboxy-2',7'-dichlorofluorescein diacetate (carboxy-DCFDA) as a cell permeant tracer

scientific article

MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features

scientific article

MicroRNA (miRNA): sequence and stability, viroid-like properties, and disease association in the CNS

scientific article

Microbiome-Derived Lipopolysaccharide (LPS) Selectively Inhibits Neurofilament Light Chain (NF-L) Gene Expression in Human Neuronal-Glial (HNG) Cells in Primary Culture

article

Microbiome-Derived Lipopolysaccharide Enriched in the Perinuclear Region of Alzheimer's Disease Brain

scientific article published on 4 September 2017

Microbiome-generated amyloid and potential impact on amyloidogenesis in Alzheimer's disease (AD).

scientific article published on July 2015

Modulatory Effects of Fingolimod (FTY720) on the Expression of Sphingolipid Metabolism-Related Genes in an Animal Model of Alzheimer's Disease.

scientific article published on 23 April 2018

Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum

scientific article

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells ⬇️

scientific article published on November 23, 2011

Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival

scientific article

Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression

scientific article (publication date: 31 October 2003)

Over-Expressed Pathogenic miRNAs in Alzheimer's Disease (AD) and Prion Disease (PrD) Drive Deficits in TREM2-Mediated Aβ42 Peptide Clearance

scientific article

Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria

scientific journal article

Prostaglandins and other lipid mediators in Alzheimer's disease

scientific article

Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases

scientific article

Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a

scientific article

Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells

scientific article

Retraction Note: Aluminum in Neurological and Neurodegenerative Disease

scientific article published on 01 March 2020

SARS-CoV-2 Infectivity and Neurological Targets in the Brain

scientific article published on 25 August 2020

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

scientific article published on 11 July 2017

Senile plaques in Alzheimer's diseased brains: possible association of beta-amyloid with herpes simplex virus type 1 (HSV-1) L-particles

scientific article

Spreading of Alzheimer’s disease inflammatory signaling through soluble micro-RNA ⬇️

scientific article published on July 11, 2012

Synergism in the repression of COX-2- and TNFalpha-induction in platelet activating factor-stressed human neural cells

scientific article

The mobilization of aluminum into the biosphere

scientific article

Up-Regulation of miRNA-146a in Progressive, Age-Related Inflammatory Neurodegenerative Disorders of the Human CNS

scientific article

Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures.

scientific article published on 27 May 2011

miRNA-155 upregulation and complement factor H deficits in Down's syndrome.

scientific article published on February 2012

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

scientific article

microRNA-Based Biomarkers and the Diagnosis of Alzheimer's Disease

scientific article

microRNA-Based Biomarkers in Alzheimer's Disease (AD)

scientific article published on 30 October 2020

List of works by Walter J Lukiw

A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States ⬇️

A microRNA cluster (let-7c, miRNA-99a, miRNA-125b, miRNA-155 and miRNA-802) encoded at chr21q21.1-chr21q21.3 and the phenotypic diversity of Down's syndrome (DS; trisomy 21)

A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells ⬇️

Addressing Alzheimer's Disease (AD) Neuropathology Using Anti-microRNA (AM) Strategies

Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer's Disease

Aluminum in Neurological and Neurodegenerative Disease

Alzheimer's disease--a dysfunction in cholesterol and lipid metabolism

Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer's disease (AD).

Analysis of RNA from Alzheimer's Disease Post-mortem Brain Tissues

Apolipoprotein E epsilon4 offers protection against age-related macular degeneration

Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD)

Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD) ⬇️

Comparing miRNAs and viroids; highly conserved molecular mechanisms for the transmission of genetic information

DNA Repair in Photoreceptor Survival ⬇️

Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer's Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7)

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders

Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.

Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models

Evolution and Complexity of Micro RNA in the Human Brain ⬇️

Evolution of microRNA (miRNA) Structure and Function in Plants and Animals: Relevance to Aging and Disease

Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer's Disease

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

HSV-1 latent rabbits shed viral DNA into their saliva

High-field 19.6T 27Al solid-state MAS NMR of in vitro aluminated brain tissue

Hypoxia signaling to genes: significance in Alzheimer's disease

Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells

Inhibition of Poly(ADP-ribose) Polymerase-1 Enhances Gene Expression of Selected Sirtuins and APP Cleaving Enzymes in Amyloid Beta Cytotoxicity

Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children

Mercury from chlor-alkali plants: measured concentrations in food product sugar

Metal-sulfate induced generation of ROS in human brain cells: detection using an isomeric mixture of 5- and 6-carboxy-2',7'-dichlorofluorescein diacetate (carboxy-DCFDA) as a cell permeant tracer

MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features

MicroRNA (miRNA): sequence and stability, viroid-like properties, and disease association in the CNS

Microbiome-Derived Lipopolysaccharide (LPS) Selectively Inhibits Neurofilament Light Chain (NF-L) Gene Expression in Human Neuronal-Glial (HNG) Cells in Primary Culture

Microbiome-Derived Lipopolysaccharide Enriched in the Perinuclear Region of Alzheimer's Disease Brain

Microbiome-generated amyloid and potential impact on amyloidogenesis in Alzheimer's disease (AD).

Modulatory Effects of Fingolimod (FTY720) on the Expression of Sphingolipid Metabolism-Related Genes in an Animal Model of Alzheimer's Disease.

Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells ⬇️

Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival

Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression

Over-Expressed Pathogenic miRNAs in Alzheimer's Disease (AD) and Prion Disease (PrD) Drive Deficits in TREM2-Mediated Aβ42 Peptide Clearance

Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria

Prostaglandins and other lipid mediators in Alzheimer's disease

Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases

Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a

Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells

Retraction Note: Aluminum in Neurological and Neurodegenerative Disease

SARS-CoV-2 Infectivity and Neurological Targets in the Brain

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

Senile plaques in Alzheimer's diseased brains: possible association of beta-amyloid with herpes simplex virus type 1 (HSV-1) L-particles

Spreading of Alzheimer’s disease inflammatory signaling through soluble micro-RNA ⬇️

Synergism in the repression of COX-2- and TNFalpha-induction in platelet activating factor-stressed human neural cells

The mobilization of aluminum into the biosphere

Up-Regulation of miRNA-146a in Progressive, Age-Related Inflammatory Neurodegenerative Disorders of the Human CNS

Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures.

miRNA-155 upregulation and complement factor H deficits in Down's syndrome.

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

microRNA-Based Biomarkers and the Diagnosis of Alzheimer's Disease

microRNA-Based Biomarkers in Alzheimer's Disease (AD)