List of works by Barry J Sessle

A focus on the Research Diagnostic Criteria for Temporomandibular Disorders

scientific article published on 01 January 2009

ATP potentiates neurotransmission in the rat trigeminal subnucleus caudalis

scientific article published in October 2006

Activation of peripheral GABAA receptors inhibits temporomandibular joint-evoked jaw muscle activity

scientific article published on 01 April 1999

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle

scientific article

Activation of peripheral P2X receptors is sufficient to induce central sensitization in rat medullary dorsal horn nociceptive neurons

scientific article published on 14 August 2012

Administration of opiate antagonist naloxone induces recurrence of increased jaw muscle activities related to inflammatory irritant application to rat temporomandibular joint region

scientific article published on 01 September 1994

Alteration of primary afferent activity following inferior alveolar nerve transection in rats.

scientific article

An electromyographic analysis of orofacial motor activities during trained tongue-protrusion and biting tasks in monkeys ⬇️

scientific article published on 01 November 1994

Animal models of chronic orofacial pain

scientific article published on 01 January 2007

Anterior pretectal nucleus-induced modulatory effects on trigeminal brainstem somatosensory neurons

scientific article published in January 1992

Are cannabinoids effective for orofacial pain states?

scientific article published on 01 December 2015

Associations between pain and neuromuscular activity in the human jaw and neck muscles

scientific article

Astroglia in medullary dorsal horn (trigeminal spinal subnucleus caudalis) are involved in trigeminal neuropathic pain mechanisms

scientific article

Astroglial glutamate-glutamine shuttle is involved in central sensitization of nociceptive neurons in rat medullary dorsal horn

scientific article published on 01 August 2007

Awareness of pain awareness

scientific article published on 01 January 2005

Biological adaptation and normative values

scientific article published on 01 January 2003

Biological adaptation and normative values

scientific article published on 01 July 2005

C-fiber depletion alters response properties of neurons in trigeminal nucleus principalis

scientific article published in February 1999

Can you be too old for oral implants? An update on ageing and plasticity in the oro-facial sensorimotor system

scientific article published on 22 July 2019

Canadian Orofacial Pain Team workshop report on the global year against orofacial pain

scientific article

Central mu opioid receptor mechanisms modulate mustard oil-evoked jaw muscle activity

scientific article

Central sensitization and MAPKs are involved in occlusal interference-induced facial pain in rats

scientific article published on May 2013

Central sensitization in medullary dorsal horn involves gap junctions and hemichannels

scientific article

Central sensitization in thalamic nociceptive neurons induced by mustard oil application to rat molar tooth pulp.

scientific article published on 24 August 2006

Central sensitization induced in thalamic nociceptive neurons by tooth pulp stimulation is dependent on the functional integrity of trigeminal brainstem subnucleus caudalis but not subnucleus oralis

scientific article published on 22 August 2006

Central sensitization induced in trigeminal and upper cervical dorsal horn neurons by noxious stimulation of deep cervical paraspinal tissues in rats with minimal surgical trauma

scientific article

Central sensitization of nociceptive neurons in rat medullary dorsal horn involves purinergic P2X7 receptors

scientific article published on 14 July 2011

Central sensitization of nociceptive neurons in trigeminal subnucleus oralis depends on integrity of subnucleus caudalis

scientific article published in July 2002

Central α-adrenoceptors contribute to mustard oil-induced central sensitization in the rat medullary dorsal horn

scientific article published on 16 January 2013

Changes in mechanoreceptive field properties of trigeminal somatosensory brainstem neurons induced by stimulation of nucleus raphe magnus in cats

scientific article published on 01 April 1989

Chapter 5--face sensorimotor cortex: its role and neuroplasticity in the control of orofacial movements

scientific article published on January 2011

Chapter 9--face sensorimotor cortex neuroplasticity associated with intraoral alterations.

scientific article published on January 2011

Characterization of esophageal defects in the Crouzon mouse model

scientific article

Combination of jaw and tongue movement training influences neuroplasticity of corticomotor pathways in humans

scientific article published on 25 July 2019

Comparison of responses of cutaneous nociceptive and nonnociceptive brain stem neurons in trigeminal subnucleus caudalis (medullary dorsal horn) and subnucleus oralis to natural and electrical stimulation of tooth pulp

scientific article published in July 1984

Corticomotor plasticity induced by tongue-task training in humans: a longitudinal fMRI study.

scientific article published on 18 May 2011

Development of regional specificity of spinal and medullary dorsal horn neurons

scientific article

Differential effects of cutaneous and deep application of inflammatory irritant on mechanoreceptive field properties of trigeminal brain stem nociceptive neurons

scientific article published on 01 October 1993

Directional information from neuronal ensembles in the primate orofacial sensorimotor cortex

scientific article published on 19 June 2013

Dura-evoked neck muscle activity involves purinergic and N-methyl-D-aspartate receptor mechanisms

scientific article published on December 2015

ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue

scientific article published on 26 April 2016

Editorial: Comorbidities Associated with Orofacial Pain and Headache: A Continuing Emphasis

scientific article published in December 2016

Effect of a peripheral NMDA receptor antagonist on glutamate-evoked masseter muscle pain and mechanical sensitization in women.

scientific article

Effect of peripheral NMDA receptor blockade with ketamine on chronic myofascial pain in temporomandibular disorder patients: a randomized, double-blinded, placebo-controlled trial.

scientific article

Effects of GABA receptor antagonist on trigeminal caudalis nociceptive neurons in normal and neonatally capsaicin-treated rats

scientific article published in November 1999

Effects of experimental pain on jaw muscle activity during goal-directed jaw movements in humans

scientific article published on 13 June 2008

Effects of incisor extraction on jaw and tongue motor representations within face sensorimotor cortex of adult rats.

scientific article published in April 2010

Effects of inflammatory irritant application to the rat temporomandibular joint on jaw and neck muscle activity.

scientific article published in February 1995

Effects of reversible bilateral inactivation of face primary motor cortex on mastication and swallowing

scientific article published in July 2002

Effects of reversible cold block of face primary somatosensory cortex on orofacial movements and related face primary motor cortex neuronal activity

scientific article published in January 2002

Effects of reversible inactivation by cooling of the primate face motor cortex on the performance of a trained tongue-protrusion task and a trained biting task

scientific article

Effects of temporomandibular joint stimulation on nociceptive and nonnociceptive neurons of the cat's trigeminal subnucleus caudalis (medullary dorsal horn)

scientific article published on 01 May 1988

Effects of tooth pulp deafferentation on nociceptive and nonnociceptive neurons of the feline trigeminal subnucleus caudalis (medullary dorsal horn)

scientific article published on 01 June 1989

Effects on mastication of reversible bilateral inactivation of the lateral pericentral cortex in the monkey (Macaca fascicularis).

scientific article published in September 2002

Endogenous ATP involvement in mustard-oil-induced central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn).

scientific article published on 18 May 2005

Evolution of the Research Diagnostic Criteria for Temporomandibular Disorders

scientific article published on 01 January 2010

Excitatory effects on neck and jaw muscle activity of inflammatory irritant applied to cervical paraspinal tissues

scientific article published in November 1993

Face sensorimotor cortex and its neuroplasticity related to orofacial sensorimotor functions

scientific article published on 08 May 2011

Face sensorimotor cortex undergoes neuroplastic changes in a rat model of trigeminal neuropathic pain.

scientific article published on 8 March 2018

Factors Influencing the Management of Chronic Orofacial Pain and Headche

scientific article published on 01 January 2015

Features of cortical neuroplasticity associated with multidirectional novel motor skill training: a TMS mapping study.

scientific article published on 11 January 2013

Features of cortically evoked swallowing in the awake primate (Macaca fascicularis).

scientific article

Fractalkine signaling in microglia contributes to ectopic orofacial pain following trapezius muscle inflammation

scientific article published in May 2013

Functional properties of neurons in cat trigeminal subnucleus caudalis (medullary dorsal horn). I. Responses to oral-facial noxious and nonnoxious stimuli and projections to thalamus and subnucleus oralis

scientific article published on 01 February 1981

Functional properties of neurons in the primate tongue primary motor cortex during swallowing

scientific article published in September 1997

Functional properties of single neurons in the primate face primary somatosensory cortex. I. Relations with trained orofacial motor behaviors

scientific article

Functional properties of single neurons in the primate face primary somatosensory cortex. II. Relations with different directions of trained tongue protrusion

scientific article

Genesis of sleep bruxism: motor and autonomic-cardiac interactions.

scientific article published on 20 February 2007

Glia: non-neural players in orofacial pain

scientific article published on 01 January 2007

Glutamate and capsaicin effects on trigeminal nociception I: Activation and peripheral sensitization of deep craniofacial nociceptive afferents

scientific article

Glutamate and capsaicin effects on trigeminal nociception II: activation and central sensitization in brainstem neurons with deep craniofacial afferent input

scientific article

Glutamate and capsaicin-induced pain, hyperalgesia and modulatory interactions in human tendon tissue

scientific article published on 13 January 2009

Glutamate-evoked jaw muscle pain as a model of persistent myofascial TMD pain?

scientific article published on 4 March 2008

Glutamate-evoked pain and mechanical allodynia in the human masseter muscle

scientific article published in February 2003

Glutamate-induced temporomandibular joint pain in healthy individuals is partially mediated by peripheral NMDA receptors

scientific article published in January 2010

Glutamine uptake contributes to central sensitization in the medullary dorsal horn

scientific article published on July 2008

Impact--a new "high" for the Journal of Orofacial Pain

scientific article published on 01 January 2003

Influence of sex on reflex jaw muscle activity evoked from the rat temporomandibular joint.

scientific article

Input-output relationships of the primary face motor cortex in the monkey (Macaca fascicularis).

scientific article

Integration of basic sciences into the predoctoral curriculum to study temporomandibular disorders and orofacial pain.

scientific article published in January 2002

Interstitial glutamate concentration is elevated in the masseter muscle of myofascial temporomandibular disorder patients

scientific article published on January 2010

Interview: Pain management challenges: research, access, costs, education and public awareness

scientific article published in January 2011

Involvement of AMPA receptor GluR2 and GluR3 trafficking in trigeminal spinal subnucleus caudalis and C1/C2 neurons in acute-facial inflammatory pain

scientific article

Involvement of ATP in noxious stimulus-evoked release of glutamate in rat medullary dorsal horn: a microdialysis study

scientific article published on 15 October 2012

Involvement of ERK phosphorylation in brainstem neurons in modulation of swallowing reflex in rats.

scientific article published on 5 January 2009

Involvement of ERK phosphorylation of trigeminal spinal subnucleus caudalis neurons in thermal hypersensitivity in rats with infraorbital nerve injury

scientific article

Involvement of NK-1 and NK-2 tachykinin receptor mechanisms in jaw muscle activity reflexly evoked by inflammatory irritant application to the rat temporomandibular joint.

scientific article published in April 1998

Involvement of NMDA receptor mechanisms in jaw electromyographic activity and plasma extravasation induced by inflammatory irritant application to temporomandibular joint region of rats ⬇️

scientific article published on November 1, 1996

Involvement of medullary GABAergic system in extraterritorial neuropathic pain mechanisms associated with inferior alveolar nerve transection

scientific article

Involvement of peripheral ionotropic glutamate receptors in orofacial thermal hyperalgesia in rats

scientific article published on 28 September 2011

Jaw electromyographic activity induced by the application of algesic chemicals to the rat tooth pulp

scientific article published in April 1999

Jaw sensorimotor control in healthy adults and effects of ageing

scientific article published on 29 August 2017

Jaw-opening and -closing premotoneurons in the nucleus of the solitary tract making contacts with laryngeal and pharyngeal afferent terminals in rats

scientific article

Jaw-opening reflex and corticobulbar motor excitability changes during quiet sleep in non-human primates

scientific article published on February 2013

Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males

scientific article

Locally released small (non-protein) ninhydrin-reacting molecules underlie developmental differences of cultured medullary versus spinal dorsal horn neurons.

scientific article published on 12 June 2012

Long-term neuroplasticity of the face primary motor cortex and adjacent somatosensory cortex induced by tooth loss can be reversed following dental implant replacement in rats

scientific article

Management of patients with refractory angina: Canadian Cardiovascular Society/Canadian Pain Society joint guidelines

scientific article published on March 2012

Mechanical and thermal hypersensitivities associated with orthodontic tooth movement: a behavioral rat model for orthodontic tooth movement-induced pain.

scientific article

Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment.

scientific article

Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats

scientific article

Mechanisms of craniofacial pain.

scientific article published in January 2017

Mechanisms underlying ectopic persistent tooth-pulp pain following pulpal inflammation

scientific article

Modulation dynamics in the orofacial sensorimotor cortex during motor skill acquisition

scientific article

Modulation of astroglial glutamine synthetase activity affects nociceptive behaviour and central sensitization of medullary dorsal horn nociceptive neurons in a rat model of chronic pulpitis

scientific article published on 27 June 2011

Modulation of trigeminal spinal subnucleus caudalis neuronal activity following regeneration of transected inferior alveolar nerve in rats

scientific article published on 12 March 2008

Morphine application to peripheral tissues modulates nociceptive jaw reflex

scientific article published on 01 October 1998

Motor cortex neuroplasticity associated with lingual nerve injury in rats

scientific article published on 01 September 2007

NMDA and Purinergic Processes Modulate Neck Muscle Activity Evoked by Noxious Stimulation of Dura

scientific article published on 12 June 2020

NMDA receptor involvement in neuroplastic changes induced by neonatal capsaicin treatment in trigeminal nociceptive neurons

scientific article published in November 1997

NMDA receptor mechanisms contribute to neuroplasticity induced in caudalis nociceptive neurons by tooth pulp stimulation

scientific article published in November 1998

Neck muscle length modulates nociceptive reflex evoked by noxious irritant application to rat neck tissues

scientific article published on 18 January 2005

Neural mechanisms of temporomandibular joint and masticatory muscle pain: a possible role for peripheral glutamate receptor mechanisms

scientific article

Neuronal activity patterns in primate primary motor cortex related to trained or semiautomatic jaw and tongue movements

scientific article published in May 2002

Neuroplastic changes in the sensorimotor cortex associated with orthodontic tooth movement in rats.

scientific article published on 10 March 2015

Neuroplastic effects of neonatal capsaicin on neurons in adult rat trigeminal nucleus principalis and subnucleus oralis

scientific article published in January 1996

Neuroplasticity induced by tooth pulp stimulation in trigeminal subnucleus oralis involves NMDA receptor mechanisms

scientific article

Nitroglycerin facilitates calcitonin gene-related peptide-induced behavior

scientific article published in August 2008

Noxious lingual stimulation influences the excitability of the face primary motor cerebral cortex (face MI) in the rat.

scientific article published on 2 July 2008

Opioid drug addiction and pain: diagnostic and management challenges

scientific article published in June 2014

Oral parafunction, pain, and the dental occlusion

scientific article published on 01 June 2012

Organization of hyperactive microglial cells in trigeminal spinal subnucleus caudalis and upper cervical spinal cord associated with orofacial neuropathic pain

scientific article published on 17 February 2012

Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis and upper cervical cord following capsaicin injection into oral and craniofacial regions in rats.

scientific article

Organization of the primate face motor cortex as revealed by intracortical microstimulation and electrophysiological identification of afferent inputs and corticobulbar projections

scientific article

Orofacial pain: an educational focus

scientific article published on 01 January 2002

P2X and NMDA receptor involvement in temporomandibular joint-evoked reflex activity in rat jaw muscles

scientific article

P2X receptors in trigeminal subnucleus caudalis modulate central sensitization in trigeminal subnucleus oralis

scientific article published in October 2002

Pain advocacy: the evolution continues, with further calls for action

scientific article published on 01 December 2012

Pain costs.

scientific article published in January 2008

Pain effects of glutamate injections into human jaw or neck muscles

scientific article published in January 2005

Painful conditioning stimuli of the craniofacial region evokes diffuse noxious inhibitory controls in men and women

scientific article published on January 1, 2010

Painful waiting

scientific article published on January 1, 2010

Parabrachial area and nucleus raphe magnus-induced modulation of electrically evoked trigeminal subnucleus caudalis neuronal responses to cutaneous or deep A-fiber and C-fiber inputs in rats

scientific article published on 01 July 1995

Parabrachial area and nucleus raphe magnus-induced modulation of nociceptive and nonnociceptive trigeminal subnucleus caudalis neurons activated by cutaneous or deep inputs

scientific article

Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats

scientific article published in June 2005

Peripheral and central mechanisms of orofacial inflammatory pain

scientific article published on January 2011

Pharmacological management of chronic neuropathic pain: revised consensus statement from the Canadian Pain Society.

scientific article

Plasticity in corticomotor control of the human tongue musculature induced by tongue-task training

scientific article published on 26 June 2003

Pregabalin suppresses nociceptive behavior and central sensitization in a rat trigeminal neuropathic pain model

scientific article published on February 2013

Presynaptic excitability changes produced in brain stem endings of tooth pulp afferents by raphe and other central and peripheral influences

scientific article published on 01 August 1981

Primary motor and sensory cortical areas communicate via spatiotemporally coordinated networks at multiple frequencies

scientific article published on 18 April 2016

Primary sensorimotor cortex exhibits complex dependencies of spike-field coherence on neuronal firing rates, field power, and behavior.

scientific article published on 28 March 2018

Properties and plasticity of the primate somatosensory and motor cortex related to orofacial sensorimotor function

scientific article

Properties of heat-sensitive neurons in the premotor cortex of conscious monkeys

scientific article published on 01 August 2020

Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity

scientific article published on 22 September 2010

Quantitative analysis of surface EMG activity of cranial and leg muscles across sleep stages in human

scientific article

Recent insights into brainstem mechanisms underlying craniofacial pain.

scientific article published on January 2002

Repeated tongue lift movement induces neuroplasticity in corticomotor control of tongue and jaw muscles in humans.

scientific article published on 20 September 2015

Reporting of adverse events and statistical details of efficacy estimates in randomized clinical trials of pain in temporomandibular disorders: Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Network

scientific article published on April 2015

Research reporting

scientific article published in January 2013

Responses of neurons in feline trigeminal subnucleus caudalis (medullary dorsal horn) to cutaneous, intraoral, and muscle afferent stimuli

scientific article published in February 1986

Role of astrocytes in pain

scientific article published on 26 May 2012

Role of glia in orofacial pain

scientific article published on 21 April 2011

SENSORY AND MOTOR FUNCTIONS OF FACE PRIMARY SOMATOSENSORY CORTEX IN THE PRIMATE

article

Sagittal Plane Kinematics of the Jaw and Hyolingual Apparatus During Swallowing in Macaca mulatta.

scientific article published on 20 May 2017

Satellite glial cell P2Y12 receptor in the trigeminal ganglion is involved in lingual neuropathic pain mechanisms in rats

scientific article

Similarity in Neuronal Firing Regimes across Mammalian Species

scientific article published on May 2016

Simultaneous modulation of the exteroceptive suppression periods in the trapezius and temporalis muscles by experimental muscle pain

scientific article published on 01 June 2004

Sleep bruxism: issues to chew on

scientific article published on January 1, 2003

Stomatodynia-burning issues

scientific article published on 01 January 2009

Surgical incision can alter capsaicin-induced central sensitization in rat brainstem nociceptive neurons

scientific article published on 5 August 2008

Systemic administration of monosodium glutamate elevates intramuscular glutamate levels and sensitizes rat masseter muscle afferent fibers

scientific article

Systemic pregabalin attenuates facial hypersensitivity and noxious stimulus-evoked release of glutamate in medullary dorsal horn in a rodent model of trigeminal neuropathic pain

scientific article

Systemic pregabalin attenuates sensorimotor responses and medullary glutamate release in inflammatory tooth pain model

scientific article

Temporomandibular disorders: associations and features related to diagnosis and management

scientific article published on 01 December 2013

The Canadian Pain Society: A historical perspective ⬇️

journal article from 'Canadian Journal of Pain' published in 2020

The effect of bilateral cold block of the primate face primary somatosensory cortex on the performance of trained tongue-protrusion task and biting tasks.

scientific article published in September 1993

The effect of glutamate-evoked masseter muscle pain on the human jaw-stretch reflex differs in men and women.

scientific article

The effect of minocycline on the masticatory movements following the inferior alveolar nerve transection in freely moving rats

scientific article

The effects of intra-oral pain on motor cortex neuroplasticity associated with short-term novel tongue-protrusion training in humans

scientific article published on 17 September 2007

The evolution of a scientific journal

scientific article published on 01 January 2002

The gap junction blocker carbenoxolone attenuates nociceptive behavior and medullary dorsal horn central sensitization induced by partial infraorbital nerve transection in rats

scientific article published on 14 November 2013

The orofacial pain publication profile

scientific article published on 01 January 2008

The pain crisis: what it is and what can be done

scientific article

The pain summit: moving the agenda forward

scientific article published on 01 January 2011

The paradox of pain from tooth pulp: low-threshold "algoneurons"?

scientific article published on September 2011

The use of opioid analgesics in the management of acute and chronic orofacial pain in Canada: the need for further research.

scientific article published in January 2014

Toll-Like Receptor 4 in the Rat Caudal Medulla Mediates Tooth Pulp Inflammatory Pain

scientific article published on 23 June 2020

Tooth extraction and subsequent dental implant placement in Sprague-Dawley rats induce differential changes in anterior digastric myofibre size and myosin heavy chain isoform expression

scientific article published on 16 January 2019

Tooth pulp deafferentation is associated with functional alterations in the properties of neurons in the trigeminal spinal tract nucleus

scientific article published in December 1986

Topographical distribution and functional properties of cortically induced rhythmical jaw movements in the monkey (Macaca fascicularis)

scientific article published on 01 March 1989

Two new entities: newly developed diagnostic criteria for temporomandibular disorders, and the Journal of Oral & Facial Pain and Headache

scientific article published on 01 December 2014

Unilateral application of an inflammatory irritant to the rat temporomandibular joint region produces bilateral modulation of the jaw-opening reflex

scientific article published in October 2005

Unrelieved pain: a crisis

scientific article published in November 2011

Vascular and psychophysical effects of topical capsaicin application to orofacial tissues

scientific article

Why are the diagnosis and management of orofacial pain so challenging?

scientific article published on 01 May 2009

Widespread Volumetric Brain Changes following Tooth Loss in Female Mice.

scientific article published on January 2016

Paulina is supported by:

About Paulina

Help