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List of works by Kazufumi Honda

A phase I study of the combination of panitumumab and bevacizumab in KRAS wild-type colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, irinotecan and bevacizumab

scientific article published on 20 July 2016

ACTN4 gene amplification and actinin-4 protein overexpression drive tumour development and histological progression in a high-grade subset of ovarian clear-cell adenocarcinomas

scientific article published on 20 February 2012

Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells

scientific article published in August 2017

Actinin-4 expression in ovarian cancer: a novel prognostic indicator independent of clinical stage and histological type

scientific article published on 14 September 2007

Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance

scientific article published on 16 January 2009

Actinin-4 increases cell motility and promotes lymph node metastasis of colorectal cancer

scientific journal article

Actinin-4 protein overexpression as a predictive biomarker in adjuvant chemotherapy for resected lung adenocarcinoma.

scientific article published on 29 June 2017

Actinin-4 splice variant - a complementary diagnostic and prognostic marker of pancreatic neuroendocrine neoplasms

scientific article published on 10 February 2020

Altered DNA methylation is associated with aberrant stemness gene expression in early‑stage HNSCC

scientific article published on 14 August 2019

Altered Plasma Apolipoprotein Modifications in Patients with Pancreatic Cancer: Protein Characterization and Multi-Institutional Validation ⬇️

scientific article published on October 8, 2012

Alternative mammalian target of rapamycin (mTOR) signal activation in sorafenib-resistant hepatocellular carcinoma cells revealed by array-based pathway profiling

scientific article

Alternative splice variant of actinin-4 in small cell lung cancer

scientific article published on July 2004

Apolipoprotein A2 Isoforms in Relation to the Risk of Myocardial Infarction: A Nested Case-Control Analysis in the JPHC Study

scientific article published on 29 August 2020

Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing.

scientific article published on October 2005

Biological significance of actinin-4 in the mechanism of cancer invasion and metastasis

scientific article published in 2012

Biomarker Discovery of Pancreatic and Gastrointestinal Cancer by 2DICAL: 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry

scientific article

CA19-9 and Apolipoprotein-A2 isoforms as detection markers for pancreatic cancer - a prospective evaluation

scientific article published on 04 December 2018

CA19-9 as a therapeutic target in pancreatitis

scientific article published on 01 December 2019

Carbonic anhydrase I as a new plasma biomarker for prostate cancer.

scientific article

Combined functional genome survey of therapeutic targets for clear cell carcinoma of the kidney

scientific article published on 15 May 2011

Combined functional genome survey of therapeutic targets for hepatocellular carcinoma

scientific article published on 13 April 2010

Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens

scientific article published on 12 January 2020

Copy number increase of ACTN4 is a prognostic indicator in salivary gland carcinoma

scientific article

Correction: Alternative mammalian target of rapamycin (mTOR) signal activation in sorafenib-resistant hepatocellular carcinoma cells revealed by array-based pathway profiling

scientific article published on 01 January 2020

Distinct gene expression-defined classes of gastrointestinal stromal tumor.

scientific article published in September 2008

E-cadherin regulates the association between beta-catenin and actinin-4

scientific article

Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4.

scientific article published on 21 April 2016

Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas

scientific article published on September 2008

Functional genome screen for therapeutic targets of osteosarcoma

scientific article

Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex

scientific article

Histological growth pattern of and alpha-actinin-4 expression in thyroid cancer

Identification of 2 serum biomarkers of renal cell carcinoma by surface enhanced laser desorption/ionization mass spectrometry

scientific article published in October 2005

Identification of Adipophilin as a Potential Plasma Biomarker for Colorectal Cancer Using Label-Free Quantitative Mass Spectrometry and Protein Microarray ⬇️

scientific article (publication date: October 2011)

Identification of IGFBP2 and IGFBP3 As Compensatory Biomarkers for CA19-9 in Early-Stage Pancreatic Cancer Using a Combination of Antibody-Based and LC-MS/MS-Based Proteomics

scientific article

Identification of a predictive biomarker for hematologic toxicities of gemcitabine

scientific article

Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics

scientific article published on 16 February 2017

Identification of serum biomarkers of chemoradiosensitivity in esophageal cancer via the targeted metabolomics approach

scientific article published on 25 July 2018

Immunohistochemical actinin-4 expression in infiltrating gliomas: association with WHO grade and differentiation

scientific article

Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis

scientific article published on 26 September 2007

Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.

scientific article published on 5 January 2007

Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins

scientific article

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling

scientific article

Label-free quantitative proteomics using large peptide data sets generated by nanoflow liquid chromatography and mass spectrometry

scientific article

Large-scale quantitative clinical proteomics by label-free liquid chromatography and mass spectrometry.

scientific article published on 19 December 2008

Leucine-Rich Alpha-2-Glycoprotein 1 in Serum Is a Possible Biomarker to Predict Response to Preoperative Chemoradiotherapy for Esophageal Cancer

scientific article published on 01 January 2019

Live single cell mass spectrometry reveals cancer-specific metabolic profiles of circulating tumor cells

scientific article published on 05 January 2019

Mass spectrometry analysis of the native protein complex containing actinin-4 in prostate cancer cells

scientific article

Measurement of copy number of ACTN4 to optimize the therapeutic strategy for locally advanced pancreatic cancer

scientific article published on 18 June 2018

Metabolomics-based Discovery of Serum Biomarkers to Predict the Side-effects of Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma

scientific article published on 01 January 2019

MicroRNA expression and functional profiles of osteosarcoma

scientific article published on 18 January 2014

Monitoring of cancer patients via next-generation sequencing of patient-derived circulating tumor cells and tumor DNA

scientific article published on 23 July 2019

Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta-catenin protein

scientific article

Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples

scientific article published on 11 March 2020

O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer

scientific article published on 31 August 2020

Plasma biomarker discovery and validation for colorectal cancer by quantitative shotgun mass spectrometry and protein microarray ⬇️

scientific article published on December 28, 2010

Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms

scientific article

Plasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancer

scientific article published on 01 February 2007

Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.

scientific article

Possible detection of pancreatic cancer by plasma protein profiling

scientific article published in November 2005

Possible prediction of chemoradiosensitivity of esophageal cancer by serum protein profiling.

scientific article

Potential usefulness of apolipoprotein A2 isoforms for screening and risk stratification of pancreatic cancer

scientific article published on 27 September 2016

Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma

scientific article published on 08 April 2020

Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma

scientific article

Prolyl 4-hydroxylation of alpha-fibrinogen: a novel protein modification revealed by plasma proteomics

scientific article published on 20 August 2009

Prospective Study Using Plasma Apolipoprotein A2-Isoforms to Screen for High-Risk Status of Pancreatic Cancer

scientific article published on 14 September 2020

Prospects for Comprehensive Analyses of Circulating Tumor Cells in Tumor Biology

scientific article published on 01 May 2020

Proteomic Approaches to the Discovery of Cancer Biomarkers for Early Detection and Personalized Medicine ⬇️

scientific article published on December 16, 2012

Quantitative proteomics using formalin-fixed paraffin-embedded tissues of oral squamous cell carcinoma

scientific article

Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development ⬇️

scientific article published on October 24, 2012

Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2

scientific article

Reduced argininosuccinate synthetase is a predictive biomarker for the development of pulmonary metastasis in patients with osteosarcoma

scientific article published on 16 February 2010

Reduced plasma level of CXC chemokine ligand 7 in patients with pancreatic cancer

scientific article published on 08 December 2010

Regulation of Wnt signaling by the nuclear pore complex

scientific article published on 10 March 2008

SOX10 is a novel marker of acinus and intercalated duct differentiation in salivary gland tumors: a clue to the histogenesis for tumor diagnosis

scientific article published on 5 April 2013

Serum albumin-associated peptides of patients with uterine endometrial cancer

scientific article

Serum apolipoprotein A2 isoforms in autoimmune pancreatitis

scientific article published on 23 February 2018

Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer

scientific article published on 19 November 2018

Soluble interleukin-6 receptor is a serum biomarker for the response of esophageal carcinoma to neoadjuvant chemoradiotherapy

scientific article published on 13 June 2013

Survival prediction for pancreatic cancer patients receiving gemcitabine treatment

scientific article

Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer

scientific article published on 25 March 2022

The alternatively spliced actinin-4 variant as a prognostic marker for metastasis in small-cell lung cancer

scientific article published in March 2015

The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer

scientific article

The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy

scientific article published on 30 May 2017

Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth

scientific article published on 8 June 2010

Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation

scientific article

Trends in biomarker discoveries for the early detection and risk stratification of pancreatic cancer using omics studies

scientific article published on 17 July 2019

Underexpression of α-1-microglobulin/bikunin precursor predicts a poor prognosis in oral squamous cell carcinoma

scientific article published on 01 October 2018

Use of Biomarkers and Imaging for Early Detection of Pancreatic Cancer

scientific article published on 19 July 2020

Use of quantitative shotgun proteomics to identify fibronectin 1 as a potential plasma biomarker for clear cell carcinoma of the kidney

scientific article published on 01 January 2011

Usefulness of serum protein profiling for prediction of preoperative chemoradiosensitivity of esophageal cancer.

scientific article published in September 2007

[Early detection of pancreatic cancer by novel proteomic technique].

scientific article

β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells

scientific article

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