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List of works by Takeshi Fukushima

A fully automated amino acid analyzer using NBD-F as a fluorescent derivatization reagent

scientific article published in November 2004

A further study on the combined use of internal standard and isotope-labeled derivatization reagent for expansion of linear dynamic ranges in liquid chromatography-electrospray mass spectrometry

scientific article published in October 2006

A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity

scientific article published on 14 July 2015

A method to evaluate the renin-angiotensin system in rat renal cortex using a microdialysis technique combined with HPLC-fluorescence detection

scientific article published in September 2002

Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice.

scientific article

Alteration in plasma and striatal levels of d-serine after d-serine administration with or without nicergoline: An in vivo microdialysis study

scientific article published on 6 September 2017

Alteration in plasma docosahexaenoic acid levels following oral administration of ethyl icosapentate to rats

scientific article published on 24 October 2019

Alteration in the plasma concentration of a DAAO inhibitor, 3-methylpyrazole-5-carboxylic acid, in the ketamine-treated rats and the influence on the pharmacokinetics of plasma D-tryptophan ⬇️

scientific article published on January 1, 2011

Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: a comparative study between enantiomers

scientific article published in April 2009

Alterations in extracellular tryptophan and dopamine concentrations in rat striatum following peripheral administration of d- and l-tryptophan: An in vivo microdialysis study ⬇️

scientific article published on August 2, 2012

Alterations in methionine to homocysteine ratio in individuals with first-episode psychosis and those with at-risk mental state

scientific article published on 13 December 2019

Alterations in serum amino acid concentrations in male and female schizophrenic patients

scientific article published on 15 February 2007

Alterations of plasma and cerebrospinal fluid glutamate levels in rats treated with the N-methyl-D-aspartate receptor antagonist, ketamine

scientific article published in June 2006

Amino acid analyses of the exosome-eluted fractions from human serum by HPLC with fluorescence detection.

scientific article published on 22 April 2018

Analysis of hydroxyl radical-induced oxidation process of glucagon by reversed-phase HPLC and ESI-MS/MS.

scientific article

Analysis of oxidation process of cholecystokinin octapeptide with reactive oxygen species by high-performance liquid chromatography and subsequent electrospray ionization mass spectrometry

scientific article

Anti-proliferative effect of Fe(III) complexed with 1-(2-hydroxy-3-methoxybenzaldehyde)-4-aminosalicylhydrazone in HepG2 cells.

scientific article

Changes in extracellular kynurenic acid concentrations in rat prefrontal cortex after D-kynurenine infusion: an in vivo microdialysis study

scientific article published on 26 November 2009

Changes in the plasma concentrations of D‐kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers ⬇️

scientific article published on November 1, 2010

Chromatographic profiles of tryptophan and kynurenine enantiomers derivatized with (S)-4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole using LC-MS/MS on a triazole-bonded column

scientific article published on 21 July 2017

Comparative study on kynurenic acid production in the rat striatum by tryptophan enantiomers: An in vivo microdialysis study ⬇️

scientific article published on March 23, 2011

Decreased l-tryptophan concentration in distinctive brain regions of mice treated repeatedly with phencyclidine ⬇️

scientific article published on May 11, 2013

Derivatization of chiral carboxylic acids with (S)-anabasine for increasing detectability and enantiomeric separation in LC/ESI-MS/MS

scientific article published on September 24, 2012

Determination of D-serine in human serum by LC-MS/MS using a triazole-bonded column after pre-column derivatization with (S)-4-(3-isothiocyanatopyrrolidin-1-yl)-7- (N, N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole

scientific article published on 05 November 2015

Determination of fluorescence-labeled asparaginyl-oligosaccharide in glycoprotein by reversed-phase ultraperformance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.

scientific article published on 13 October 2007

Determination of fluoxetine and norfluoxetine in rat plasma by HPLC with pre-column derivatization and fluorescence detection

scientific article

Determination of fluoxetine enantiomers in rat plasma by pre-column fluorescence derivatization and column-switching high-performance liquid chromatography

scientific article published in April 2002

Determination of free fatty acids in human serum by HPLC with fluorescence detection

scientific article published on 17 July 2014

Determination of kynurenic acid levels in rat brain microdialysis samples and changes in kynurenic acid levels induced by N-acetylaspartic acid

scientific article

Determination of kynurenine levels in rat plasma by high-performance liquid chromatography with pre-column fluorescence derivatization

scientific article published on 19 November 2006

Determination of l-tryptophan and l-kynurenine derivatized with (R)-4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole by LC-MS/MS on a triazole-bonded column and their quantification in human serum

scientific article

Determination of l-tryptophan and l-kynurenine in Human Serum by using LC-MS after Derivatization with (R)-DBD-PyNCS.

scientific article published on 21 July 2013

Determination of psilocin in magic mushrooms and rat plasma by liquid chromatography with fluorimetry and electrospray ionization mass spectrometry

article

Determination of psilocybin in hallucinogenic mushrooms by reversed-phase liquid chromatography with fluorescence detection

scientific article published on 6 January 2005

Determination of rat blood S-D-lactoylglutathione by a column-switching high-performance liquid chromatography with precolumn fluorescence derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole

scientific article

Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection

scientific article

Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization

scientific article published on 19 July 2003

Determination of sex-based differences in serum γ-linolenic [corrected] acid and dihomo-γ-linolenic [corrected] acid using gas chromatography-mass spectrometry

scientific article published on 09 June 2015

Development of a 6-hydroxychroman-based derivatization reagent: application to the analysis of 5-hydroxytryptamine and catecholamines by using high-performance liquid chromatography with electrochemical detection

scientific article

Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma

scientific article published on 21 January 2007

Development of a fluorescent chelating ligand for gallium ion having a quinazoline structure with two Schiff base moieties

scientific article published on 10 January 2009

Development of a fluorescent chelating ligand for scandium ion having a Schiff base moiety

scientific article published on 16 January 2012

Development of a fluorimetric detection method for cinnabarinic acid using ortho-tolyl hydrazine as the derivatization reagent

scientific article

Development of a quinazoline-based chelating ligand for zinc ion and its application to validation of a zinc-ion-coordinated compound

scientific article published in June 2010

Development of an HPLC-fluorescence determination method for carboxylic acids related to the tricarboxylic acid cycle as a metabolome tool

scientific article published in December 2005

Effect of risperidone on plasma d-serine concentration in rats post-administered with d-serine

scientific article published on 25 June 2016

Enantiomeric Separation of Monosubstituted Tryptophan Derivatives and Metabolites by HPLC with a Cinchona Alkaloid-Based Zwitterionic Chiral Stationary Phase and Its Application to the Evaluation of the Optical Purity of Synthesized 6-Chloro-l-Trypt

scientific article published on 7 January 2015

Enantiomeric separation of D,L-tryptophan and D,L-kynurenine by HPLC using pre-column fluorescence derivatization with R(-)-DBD-PyNCS.

scientific article

Enantiomeric separation of D- and L-serine using high-performance liquid chromatography with electrochemical detection following pre-column diastereomer derivatization

scientific article

Enantiomeric separation of tolperisone and eperisone by reversed‐phase HPLC with cellulose tris(3‐chloro‐4‐methylphenylcarbamate)‐coated chiral column ⬇️

scientific article published on March 15, 2013

Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages ⬇️

scientific article published on 04 August 2011

Erratum to "Determination of sex-based differences in serum γ-linoleic acid and dihomo-γ-linoleic acid using gas chromatography-mass spectrometry" [J. Chromatogr. B 997 (2015) 116-121]

scientific article published on 25 March 2016

Estrogen receptor binding assay method for endocrine disruptors using fluorescence polarization

scientific article published in September 2002

Evaluation of human D-amino acid oxidase inhibition by anti-psychotic drugs in vitro

scientific article published on 01 June 2014

Fluorescence determination of D- and L-tryptophan concentrations in rat plasma following administration of tryptophan enantiomers using HPLC with pre-column derivatization

scientific article published on 13 February 2011

Fluorescence determination of N-acetylaspartic acid in the rat cerebrum homogenate using high-performance liquid chromatography with pre-column fluorescence derivatization

scientific article

Fluorimetric assay for D-amino acid oxidase activity in rat brain homogenate by using D-kynurenine as a substrate ⬇️

scientific article published on October 1, 2012

Fluorimetric determination of the enantiomers of vigabatrin, an anti-epileptic drug, by reversed-phase HPLC with a novel diastereomer derivatisation reagent

scientific article published on 29 December 2020

Fully automated two-dimensional high-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry for the determination of oligosaccharides in glycopeptides after enzymic fluorescence labeling

scientific article published on 13 April 2007

HPLC-fluorescence determination of thiol compounds in the serum of human male and female subjects using HILIC-mode column.

scientific article

Hair analysis of histamine after fluorescence labeling by column-switching reversed-phase liquid chromatography with electrospray ionization mass spectrometry and application to human hair

scientific article published in October 2004

Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): influence of hair cycle and age

scientific article published on 23 November 2006

Inhibition of D-Amino Acid Oxidase Activity by Antipsychotic Drugs Evaluated by a Fluorometric Assay Using D-Kynurenine as Substrate ⬇️

scientific article published on 01 January 2011

Intravenous administration of 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxy chroman (gamma-CEHC) to rats and determination of its plasma concentration and urinary sodium excretion

scientific article

LC-MS/MS Analysis of Thiol-Containing Amino Acids in Exosomal Fraction of Serum

scientific article published on 24 June 2020

Liquid chromatography-mass spectrometry with triazole-bonded stationary phase for N-methyl-D-aspartate receptor-related amino acids: development and application in microdialysis studies

scientific article published on 18 October 2017

Novel d-gamma-tocopherol derivative as a prodrug for d-gamma-tocopherol and a two-step prodrug for S-gamma-CEHC.

scientific article published in December 2002

Preparation and in vivo evaluation of a water-soluble prodrug for 2R-gamma-tocotrienol and as a two-step prodrug for 2,7,8-trimethyl-2S-(beta-carboxyethyl)-6-hydroxychroman (S-gamma-CEHC) in rat

scientific article published on 30 May 2007

Quantitative analyses of schizophrenia-associated metabolites in serum: serum D-lactate levels are negatively correlated with gamma-glutamylcysteine in medicated schizophrenia patients

scientific article

Rapid detection of ketamine and norketamine in rat hair using micropulverized extraction and ultra-performance liquid chromatography-electrospray ionization mass spectrometry

scientific article

Rapid determination of histamine and its metabolites in mice hair by ultra-performance liquid chromatography with time-of-flight mass spectrometry

scientific article published on 01 September 2006

Recent progress in derivatization methods for LC and CE analysis

scientific article

Recent progress in the development of derivatization reagents having a benzofurazan structure

scientific article

Resolution of N-linked oligosaccharides in glycoproteins based upon transglycosylation reaction by CE-TOF-MS.

scientific article

Resolution of oligosaccharides in glycopeptides using immobilized Endo-M and ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry

scientific article published on 01 August 2007

Selective and sensitive determination of lipoyllysine (protein-bound alpha-lipoic acid) in biological specimens by high-performance liquid chromatography with fluorescence detection.

scientific article published on 7 May 2008

Serum d- and l-lactate, pyruvate and glucose levels in individuals with at-risk mental state and correlations with clinical symptoms

scientific article published on 11 August 2019

Simple and practical derivatization procedure for enhanced detection of carboxylic acids in liquid chromatography-electrospray ionization-tandem mass spectrometry

scientific article published in September 2010

Simultaneous determination of D- and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection

scientific article

Simultaneous determination of N-acetylaspartylglutamate and N-acetylaspartate in rat brain homogenate using high-performance liquid chromatography with pre-column fluorescence derivatization

scientific article published on 18 September 2008

Simultaneous determination of alpha-lipoic acid and its reduced form by high-performance liquid chromatography with fluorescence detection

scientific article published on 13 April 2007

Stereoselective effect of kynurenine enantiomers on the excretion of serotonin and its metabolite in rat urine.

scientific article published in February 2010

Study on interactions of endocrine disruptors with estrogen receptor using fluorescence polarization

scientific article published in August 2003

Succinimidyl (3-[(benzyloxy)carbonyl]-5-oxo-1,3-oxazolidin-4-yl)acetate on a triazole-bonded phase for the separation of dl-amino-acid enantiomers and the mass-spectrometric determination of chiral amino acids in rat plasma

scientific article published on 28 November 2018

Suppression of thiol exchange reaction in the determination of reduced-form thiols by high-performance liquid chromatography with fluorescence detection after derivatization with fluorogenic benzofurazan reagent, 7-fluoro-2,1,3-benzoxadiazole-4-sulf

scientific article published in June 2006

Synthesis of 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-methylhydrazino-2,1,3-benzoxadiazole (DAABD-MHz) as a derivatization reagent for aldehydes in liquid chromatography/electrospray ionization-tandem mass spectrometry

scientific article

Synthesis of benzofurazan derivatization reagents for carboxylic acids in liquid chromatography/electrospray ionization-tandem mass spectrometry.

scientific article

Synthesis of benzofurazan derivatization reagents for short chain carboxylic acids in liquid chromatography/electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS).

scientific article

Synthesis of fluorescent label, DBD-beta-proline, and the resolution efficiency for chiral amines by reversed-phase chromatography

scientific article published in January 2005

Synthesis of the isotope-labeled derivatization reagent for carboxylic acids, 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperazino-2,1,3-benzoxadiazole (d6) [DBD-PZ-NH2 (D)], and its application to the quantification and the determination of [...]

scientific article published in April 2006

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