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List of works by Takahiro Iwao

Absorption and metabolic extraction of diltiazem from the perfused rat small intestine

scientific article

An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity

scientific article published on 10 December 2013

Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease

scientific article published on 01 January 2020

Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells.

scientific article

Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes

scientific article published on 11 April 2019

Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes

scientific article published on 09 March 2020

Contribution of rat embryonic stem cells to xenogeneic chimeras in blastocyst or 8-cell embryo injection and aggregation

scientific article published on 30 October 2018

Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells

scientific article published on 01 August 2018

Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates

scientific article published on 26 August 2016

Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration

scientific article published on 05 August 2019

Differentiation of human induced pluripotent stem cells into functional enterocyte-like cells using a simple method

scientific article published on 2 July 2013

Effect of Celecoxib on Differentiation of Human Induced Pluripotent Stem Cells into Hepatocytes Involves STAT5 Activation

scientific article published on 29 August 2018

Effect of Lactobacillus casei on the absorption of nifedipine from rat small intestine

scientific article published on 01 April 2007

Efficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic Functions

scientific article published on 29 June 2018

Efficient differentiation and purification of human induced pluripotent stem cell-derived endothelial progenitor cells and expansion with the use of inhibitors of ROCK, TGF-β, and GSK3β

scientific article published on 03 March 2020

Establishment of a novel culture method for maintaining intestinal stem cells derived from human induced pluripotent stem cells

scientific article published on 09 January 2020

Functional analysis of carboxylesterase in human induced pluripotent stem cell-derived enterocytes

scientific article published on 8 March 2017

Gellan Gum Promotes the Differentiation of Enterocytes from Human Induced Pluripotent Stem Cells

scientific article published on 10 October 2020

Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells.

scientific article

Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds

scientific article published on 3 February 2015

Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells

scientific article

Human small intestinal epithelial cells differentiated from adult intestinal stem cells as a novel system for predicting oral drug absorption in humans

scientific article published on 8 September 2014

Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into enterocytes

scientific article published on 17 February 2016

Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells

scientific article published on 26 May 2020

In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome

scientific article published on 10 May 2019

Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures

scientific article published on 07 June 2019

Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity

scientific article published on 30 March 2020

Metabolic extraction of nifedipine during absorption from the rat small intestine

scientific article published in January 2002

Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells

scientific article published on 16 May 2020

Selective culture method for hepatocyte-like cells differentiated from human induced pluripotent stem cells

scientific article published on 29 April 2014

Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage

article

[Development of an In Vitro System for Evaluating Intestinal Drug Disposition Using Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells]

scientific article published on 01 January 2018

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