List of works by Mrinal Gounder

365 Epigenetic Profiling Reveals a Unique Histone Code in Chordoma

scientific article

A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas

scientific article

A first-in-human phase I study of MORAb-004, a monoclonal antibody to endosialin in patients with advanced solid tumors

scientific article

A phase 1b dose expansion study of the pan-class I PI3K inhibitor buparlisib (BKM120) plus carboplatin and paclitaxel in PTEN deficient tumors and with dose intensified carboplatin and paclitaxel

scientific article published on 9 March 2017

ATNT-17EVALUATION OF THE SAFETY AND BENEFIT OF PHASE I ONCOLOGY TRIALS FOR PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS.

scientific article

Activity of Sorafenib against desmoid tumor/deep fibromatosis

scientific article

Beyond the dose-limiting toxicity period: Dermatologic adverse events of patients on phase 1 trials of the Cancer Therapeutics Evaluation Program

scientific article

Clinical and Morphologic Characteristics of MEK Inhibitor-Associated Retinopathy: Differences from Central Serous Chorioretinopathy

scientific article published on 12 July 2017

Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab

scientific article published on 22 December 2016

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

scientific article published on 01 August 2017

Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.

scientific article published on 17 August 2015

First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement

scientific article

G-CSF is not necessary to maintain over 99% dose-intensity with ABVD in the treatment of Hodgkin lymphoma: low toxicity and excellent outcomes in a 10-year analysis.

scientific article published on 24 April 2007

Genomic aberrations frequently alter chromatin regulatory genes in chordoma

scientific article

Impact of race on dose selection of molecular-targeted agents in early-phase oncology trials

scientific article published on 24 May 2018

Impact of surgery, radiation and systemic therapy on the outcomes of patients with dendritic cell and histiocytic sarcomas

scientific article published on 19 August 2015

Inclusion of patients with brain metastases in phase I trials: an unmet need.

scientific article published on 28 April 2011

Locally Aggressive Connective Tissue Tumors.

scientific article published on 8 December 2017

Molecular basis for primary and secondary tyrosine kinase inhibitor resistance in gastrointestinal stromal tumor ⬇️

scientific article published on November 30, 2010

Moving forward one Notch at a time

scientific article published on 07 May 2012

Multidisciplinary management of recurrent chordomas

scientific article

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

scientific article published on 8 May 2017

Nomogram to predict cycle-one serious drug-related toxicity in phase I oncology trials

scientific article published on 13 January 2014

Notch inhibition in desmoids: "Sure it works in practice, but does it work in theory?"

scientific article published on 08 September 2015

OncoKB: A Precision Oncology Knowledge Base

scientific article published on 16 May 2017

Outcomes of Systemic Therapy for Patients with Metastatic Angiosarcoma

scientific article published on 3 June 2015

Pharmacovigilance and reporting oversight in US FDA fast-track process: bisphosphonates and osteonecrosis of the jaw.

scientific article published on December 2008

Phase 1 study of narnatumab, an anti-RON receptor monoclonal antibody, in patients with advanced solid tumors

scientific article

Phase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma

scientific article

Phase II Trial of Gemcitabine and Docetaxel with Bevacizumab in Soft Tissue Sarcoma.

scientific article published on 14 May 2015

Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.

scientific article

Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations

scientific article published on 08 August 2019

Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials

scientific article

Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment

scientific article

Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial.

scientific article published on 28 April 2016

Quantitative method for the determination of iso-fludelone (KOS-1803) in human plasma by LC-MS/MS.

scientific article

Reply to E. Younger et al

scientific article published on 18 April 2018

Reply to M. Voskoboynik et al

scientific article published on 28 July 2014

Sorafenib for Advanced and Refractory Desmoid Tumors

scientific article published on 20 December 2018

Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network

scientific article published on 19 September 2019

The PARP Inhibitor Veliparib Can Be Safely Added to Bendamustine and Rituximab and Has Preliminary Evidence of Activity in B-Cell Lymphoma

scientific article

The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA

scientific article published on 11 October 2019

The impact of non-drug-related toxicities on the estimation of the maximum tolerated dose in phase I trials

scientific article

Toxicity Attribution in Phase I Trials: Evaluating the Effect of Dose on the Frequency of Related and Unrelated Toxicities

scientific article published on 31 August 2015

Trametinib in Histiocytic Sarcoma with an Activating MAP2K1 (MEK1) Mutation.

scientific article

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

scientific article published on 14 January 2019

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