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List of works by Isabelle Cleynen

A Matrix-based Model Predicts Primary Response to Infliximab in Crohn's Disease

scientific article published on 07 September 2015

ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior.

scientific article

An efficient algorithm to perform multiple testing in epistasis screening.

scientific article

Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.

scientific article published on 23 September 2017

Cellular diversity in the colon: another brick in the wall

scientific article published on 01 July 2019

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

scientific article published on 27 January 2009

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

scientific article

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC.

scientific article published on 7 October 2016

Emperipolesis and cell death in NOD2-related Blau Syndrome and Crohn’s disease.

scientific article

Evolution of cytokines and inflammatory biomarkers during infliximab induction therapy and the impact of inflammatory burden on primary response in patients with Crohn's disease

scientific article published on 16 June 2017

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

scientific article

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

Genetic Influences on the Development of Fibrosis in Crohn's Disease

scientific article

Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease.

scientific article published on 6 September 2017

Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease

scientific article published on 03 October 2013

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress.

scientific article

Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review

scientific article

Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

scientific article published on 21 December 2012

Genetic risk profiling and prediction of disease course in Crohn's disease patients

scientific article

Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome

scientific article

Genetic variants in autophagy-related genes and granuloma formation in a cohort of surgically treated Crohn's disease patients

article

Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.

scientific article

Genetic variation in the lymphotoxin-α (LTA)/tumour necrosis factor-α (TNFα) locus as a risk factor for idiopathic achalasia

scientific article published on 20 November 2013

Genetics of inflammatory bowel disease: beyond NOD2.

scientific article published on 9 February 2017

Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease

scientific article published on 20 November 2015

Granuloma-in-follicles in pediatric Crohn’s disease

scientific article published on 14 September 2011

HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB

scientific article

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

Immunogenicity to infliximab is associated with HLA-DRB1.

scientific article published on 15 April 2015

Inflammatory bowel disease and Parkinson's disease: common pathophysiological links

scientific article published on 16 October 2020

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

scientific article

Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab

scientific article published in January 2013

Levels of C-reactive Protein Are Associated With Response to Infliximab Therapy in Patients With Crohn's Disease

article

Molecular Changes in the Non-Inflamed Terminal Ileum of Patients with Ulcerative Colitis

scientific article published on 28 July 2020

Molecular Profiling of Inflammatory Bowel Disease: Is It Ready for Use in Clinical Decision-Making?

scientific article published on 04 June 2019

Molecular reclassification of Crohn's disease by cluster analysis of genetic variants

scientific article

Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment

scientific article

Paradoxical inflammation induced by anti-TNF agents in patients with IBD.

scientific article published on 03 July 2012

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus ⬇️

scientific article

Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses

scientific article published on 17 June 2019

RISK stratification in paediatric Crohn's disease

scientific article published in March 2017

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

scientific article

Risk Stratification for Surgery in Stricturing Ileal Crohn's Disease: The BACARDI Risk Model

scientific article published on 3 August 2017

Serum S100A12 as a new marker for inflammatory bowel disease and its relationship with disease activity

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

scientific article published on 6 August 2015

TREM-1, the ideal predictive biomarker for endoscopic healing in anti-TNF-treated Crohn's disease patients?

scientific article published on 14 July 2018

The HMGA proteins: a myriad of functions (Review).

scientific article

The genetic architecture of inflammatory bowel disease: past, present and future

scientific article

The role of Haptoglobin and its related protein, Zonulin, in inflammatory bowel disease

scientific article

Transcriptional control of the human high mobility group A1 gene: basal and oncogenic Ras-regulated expression

scientific article published on May 2007

Validation of the "United Registries for Clinical Assessment and Research" (UR-CARE), a European online registry for clinical care and research in Inflammatory Bowel Disease.

scientific article published on 3 February 2018

Withdrawal of immunomodulators after co-treatment does not reduce trough level of infliximab in patients with Crohn's disease.

scientific article published on 25 July 2014

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