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List of works by Jeremy N Rich

"PEAR-ing" Genomic and Epigenomic Analyses for Cancer Gene Discovery.

scientific article published on October 2015

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

scientific article published on 01 July 2019

A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries

scientific article published on 01 July 2020

A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo

scientific article published on 19 February 2016

A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth

scientific article published on June 2007

A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost

scientific article

A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function

scientific article published on 5 February 2018

AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma

scientific article published on September 2006

ABERRANT SPLICING OF A BRAIN-ENRICHED ALTERNATIVE EXON ELIMINATES TUMOR SUPPRESSOR FUNCTION AND PROMOTES ONCOGENE FUNCTION DURING BRAIN TUMORIGENESIS.

scientific article published in July 2014

AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells

scientific article published on 14 June 2018

APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2

scientific article published on 14 September 2006

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

scientific article published on 20 April 2019

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.

scientific article published on 2 December 2016

Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin

scientific article published on 14 December 2020

An epigenetic gateway to brain tumor cell identity

scientific article published on December 2015

Antiangiogenic therapy in malignant glioma: promise and challenge

scientific article published on January 2007

Aptamer identification of brain tumor-initiating cells

scientific article published on 24 June 2013

Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth

scientific article published on 14 October 2015

Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology

scientific article

Bevacizumab plus irinotecan in recurrent WHO grade 3 malignant gliomas

scientific article published on November 2008

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

scientific article published in October 2007

Biology of glioma cancer stem cells

scientific article published on 20 July 2009

Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model

scientific article published on 17 February 2003

Brain cancer stem cells display preferential sensitivity to Akt inhibition

scientific article published on 18 September 2008

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

scientific article

Brain tumor stem cells: Molecular characteristics and their impact on therapy

scientific article

CBIO-20GLIOBLASTOMA SPECIFIC PROTEINS IDENTIFIED THROUGH COMBINED IN VITRO AND IN VIVO PHAGE DISPLAY BIOPANNING.

scientific article

CBIO-21. DNA HELICASE HELLS MAINTAINS GLIOMA STEM CELLS

CBIO-28NIX PROMOTES GLIOBLASTOMA CELL SURVIVAL UNDER STRESS THROUGH MITOPHAGY.

scientific article

CBMT-47. THE ROLE OF PHOSPHOFRUCTOKINASE-1 IN GLIOBLASTOMA MAINTENANCE AND MOTILITY

scientific article published on 5 November 2018

CDC20 maintains tumor initiating cells

scientific article

CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

scientific article published on 16 December 2020

CS-21EphA2 PROMOTES INFILTRATIVE INVASION OF GLIOMA STEM CELLS IN VIVO THROUGH CROSSTALK WITH Akt AND REGULATES STEM PROPERTIES

Cadherin-11 regulates motility in normal cortical neural precursors and glioblastoma

scientific article

Cancer Stem Cells: The Architects of the Tumor Ecosystem

scientific article published on 01 January 2019

Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression

scientific article

Cancer stem cells in glioblastoma

scientific article published in June 2015

Cancer stem cells in gliomas: identifying and understanding the apex cell in cancer's hierarchy

scientific article

Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance

scientific article

Challenges to curing primary brain tumours

scientific article published on 01 August 2019

Changing the fate of cancer, one splice at a time

scientific article published on 22 August 2013

Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.

scientific article published on 09 December 2013

Chemotherapy and cancer stem cells

scientific article published in October 2007

Chemotherapy and novel therapeutic approaches in malignant glioma

scientific article

Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma

scientific article published on 04 April 2019

Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC

scientific article published on 04 April 2019

Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells

scientific article published on 21 March 2016

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.

scientific article

Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice

scientific article published on 21 November 2017

Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling

scientific article published on 15 September 2015

Correction: Zika virus has oncolytic activity against glioblastoma stem cells

scientific article published on 15 September 2017

DRES-05. IDENTIFYING DRIVERS OF CHEMORESISTANCE IN GROUP 3 MEDULLOBLASTOMA THROUGH A GENOME-WIDE CRISPR/Cas9 ACTIVATION SCREEN

Deadly teamwork: neural cancer stem cells and the tumor microenvironment

scientific article

Decoding the cancer stem cell hypothesis in glioblastoma

scientific article published on July 2013

Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination

scientific article published on 06 December 2016

Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells ⬇️

scientific article published on January 23, 2011

Development of a Sox2 reporter system modeling cellular heterogeneity in glioma

scientific article published on 21 November 2014

Development of novel targeted therapies in the treatment of malignant glioma

scientific article published on May 2004

Diagnosis and treatment of high-grade astrocytoma

scientific article

Differential connexin function enhances self-renewal in glioblastoma

scientific article

Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

scientific article published on 30 May 2016

Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells

scientific article

Distinct requirements for Ras oncogenesis in human versus mouse cells

scientific article

Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma

scientific article published on 15 June 2020

EPND-01. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS.

scientific article published on 31 May 2017

ET-36HYPERTHERMIA IMPROVES THE RADIOSENSITIVITY OF GLIOMA STEM CELLS BY INHIBITION OF AKT SIGNALING.

scientific article published in November 2014

EXTH-37. TARGETING GLIOMA STEM CELLS THROUGH COMBINED BMI1 AND EZH2 INHIBITION

EXTH-75. IMAGING GLIOBLASTOMA STEM CELLS WITH 7-AMINO ACID-LENGTH TUMOR-HOMING PEPTIDE IDENTIFIED BY PHAGE DISPLAY BIOPANNING

scientific article published on 6 November 2017

Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well-Being: The STRIDE Study

scientific article published on 09 October 2020

Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma

scientific article published on 28 August 2008

Elevated invasive potential of glioblastoma stem cells ⬇️

scientific article published on March 25, 2011

Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma

scientific article published on 6 March 2012

Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance

scientific article

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

scientific article published on 18 December 2020

Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.

scientific article published on 5 May 2015

Functional Enhancers Shape Extrachromosomal Oncogene Amplifications

scientific article published on 21 November 2019

GENE-30. TRANSCRIPTION ELONGATION FACTORS REPRESENT CANCER DEPENDENCIES IN GLIOBLASTOMA

GENE-32. ACTIVE CHROMATIN REGULATORY MAPS IDENTIFY CORE CELL STATE DRIVERS OF GLIOBLASTOMA.

scientific article published on 6 November 2017

GLIOBLASTOMA STEM CELL-DERIVED PERICYTES AND TUMOR ANGIOGENESIS.

scientific article published in July 2014

Gene expression profiling and genetic markers in glioblastoma survival.

scientific article published in May 2005

Genomics informs glioblastoma biology

scientific article

Glioblastoma Stem Cells: A Neuropathologist's View ⬇️

scientific article published on January 1, 2011

Glioblastoma Stem Cells: Driving Resilience through Chaos

scientific article published on 03 February 2020

Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

scientific article published on March 2013

Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer

scientific article published on 01 June 2019

Glioma Development: Where Did It All Go Wrong? ⬇️

scientific article published on July 22, 2011

Glioma Stem Cell Maintenance: The Role of the Microenvironment ⬇️

scientific article published on January 1, 2011

Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling

scientific article published on 14 June 2019

Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy

scientific article

Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2

scientific article

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

scientific article (publication date: 7 December 2006)

Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation

scientific article published on 01 May 2020

Growth Factor Receptor Fusions Predict Therapeutic Sensitivity

scientific article

Growth Factor Receptors Define Cancer Hierarchies ⬇️

scientific article published on February 11, 2013

HG-06INHIBITION OF EPIGENETIC REGULATION AS A THERAPY FOR PEDIATRIC HIGH GRADE GLIOMA.

scientific article published on 21 April 2015

HIF induces human embryonic stem cell markers in cancer cells.

scientific article

High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues ⬇️

scientific article

High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas

scientific article published in June 2003

High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor

scientific article published on 27 December 2013

Holding on to stemness ⬇️

scientific article published on 02 May 2012

Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling

scientific article

Hypoxia and hypoxia inducible factors in cancer stem cell maintenance

scientific article published on January 2010

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

scientific article published on June 2009

IMMU-47. HARNESSING ZIKA VIRUS (ZIKV) ONCOLYTIC ACTIVITY IN BRAIN TUMORS

scholarly article by Arijita Jash et al published 5 November 2018 in Neuro-Oncology

INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS.

scientific article published in July 2014

Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance.

scientific article

Inhibition of ID1-BMPR2 Intrinsic Signaling Sensitizes Glioma Stem Cells to Differentiation Therapy

scientific article published on 5 December 2017

Integrin alpha 6 regulates glioblastoma stem cells

scientific article

L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1 ⬇️

scientific article published on February 4, 2011

Laminin alpha 2 enables glioblastoma stem cell growth

scientific article published on November 2012

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival ⬇️

scientific article published on July 11, 2011

Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.

scientific article published on 14 October 2013

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma

scientific article published on 13 December 2021

Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development.

scientific article

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

scientific article

Looking in the miR-ror: TGF-β–mediated activation of NF-κB in glioma ⬇️

scientific article published on September 24, 2012

Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity

scientific article published on December 2005

Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy

scientific article

MEDU-22. IDENTIFYING DRIVERS OF CHEMORESISTANCE IN GROUP 3 MEDULLOBLASTOMA THROUGH A CRISPR/CAS9 GENOME-WIDE ACTIVATION SCREEN.

scientific article

MET Signaling Regulates Glioblastoma Stem Cells ⬇️

scientific article published on May 22, 2012

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin

scientific article published on 25 November 2015

MOLECULAR MOTORS AS NOVEL TARGETS TO BLOCK GLIOMA DISPERSION AND PROLIFERATION.

scientific article published in July 2014

MR-01MicroRNA-145 REGULATES JAM-A EXPRESSION AND COMPROMISES GLIOBLASTOMA MAINTENANCE.

scientific article published in November 2014

MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells.

scientific article published on 20 July 2017

Malignant glioma drug discovery – targeting protein kinases ⬇️

scientific article published on January 1, 2007

Mechanism of Action of Methotrexate Against Zika Virus

scientific article published on 10 April 2019

Medical oncology: treatment and management of malignant gliomas

scientific article published in February 2010

Messenger RNA Methylation Regulates Glioblastoma Tumorigenesis.

scientific article published in April 2017

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma

scientific article published on 20 May 2020

Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma

scientific article published on 05 September 2019

Mitochondrial control by DRP1 in brain tumor initiating cells

scientific article

Mitotic control of cancer stem cells.

scientific article published on February 2013

Molecular Targeting of Neural Cancer Stem Cells: TTAGGG, You're It! ⬇️

scientific article published on January 1, 2011

Molecularly targeted therapy for malignant glioma

scientific article published on July 2007

Multiplex flow cytometry barcoding and antibody arrays identify surface antigen profiles of primary and metastatic colon cancer cell lines

scientific article

N-methyladenine DNA Modification in Glioblastoma

scientific article published on 01 November 2018

NDRG4 is required for cell cycle progression and survival in glioblastoma cells

scientific article published on 10 July 2009

Nicotinamide metabolism regulates glioblastoma stem cell maintenance

scientific article

Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3 ⬇️

scientific article published on April 12, 2011

Notch Signaling in Cancer Stem Cells ⬇️

scientific article published on January 1, 2012

Notch promotes radioresistance of glioma stem cells

scientific article published on 01 January 2010

Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results

scientific article

Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

scientific article published on 11 July 2019

Outcome after bevacizumab clinical trial therapy among recurrent grade III malignant glioma patients

scientific article

Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy

scientific article

PARP inhibition sensitizes colorectal cancer-initiating cells to chemotherapy

scientific article published on 12 November 2018

PDTM-23. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS

Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway

scientific article

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

scientific article

Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma ⬇️

scientific article published on October 9, 2011

Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models

scientific article published on 26 February 2016

Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma

scientific article published on 10 March 2012

Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma

scientific article

Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma

scientific article published on April 2004

Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma

scientific article published on April 2004

Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma

scientific article

Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma

scientific article published in October 2005

Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma

scientific article

Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma

scientific article

Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme

scientific article

Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma

scientific article

Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas

scientific article

Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme

scientific article

Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy

scientific article

Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme

scientific article published on February 2009

Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma

scientific article

Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma

scientific article published in February 2007

Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma

scientific article published on May 2002

Phase II trial of gefitinib in recurrent glioblastoma

scientific article published on 24 November 2003

Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma

scientific article published in January 2005

Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas

scientific article published in March 2002

Phase II trial of temozolomide in patients with progressive low-grade glioma

scientific article

Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma

scientific article

Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

scientific article

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity

scientific article

Potential therapeutic implications of cancer stem cells in glioblastoma

scientific article

Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells

scientific article

Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation

scientific article

Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malig

scientific article published in October 2003

Protein Sumoylation with SUMO1 Promoted by Pin1 in Glioma Stem Cells Augments Glioblastoma Malignancy

scientific article published on 27 June 2020

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma.

scientific article published on 27 March 2017

RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation

scientific article published on 20 June 2016

Recent advances in the treatment of malignant astrocytoma

scientific article

Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness

scientific article published on 22 December 2009

Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression

scientific article published in April 2018

Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'

scientific article published on 01 August 2019

Reprogramming the microenvironment: tricks of tumor-derived astrocytes

scientific article published on 18 May 2020

Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme

scientific article published on May 2004

Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance

scientific article published on 4 June 2014

SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells

scientific article published on 30 October 2020

SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.

scientific article

SC-08TRANSCRIPTIONAL AND POST-TRANSLATIONAL REGULATIONS OF c-Myc IN GLIOBLASTOMA STEM CELLS.

scientific article

SC-11DIFFERENTIAL CONNEXIN FUNCTION ENHANCES SELF-RENEWAL IN GLIOBLASTOMA.

scientific article published in November 2014

SC-13ID1-CULLIN3 AXIS REGULATES STEM CELL SIGNALING IN GLIOMA.

scientific article published in November 2014

SC-22GLIOMA STEM CELLS INTERNALIZE BEVACIZUMAB FOUND IN THE PERIVASCULAR NICHE AND TARGET IT FOR RECYCLING OR DEGRADATION

SC-32TARGETING PROLIFERATION AND INVASION IN GLIOBLASTOMA VIA MITOTIC KINESINS.

scientific article

SCDT-23. VISUALIZATION OF BRAIN TUMOR BY NEAR-INFRARED FLUORESCENCE IMAGING VIA TUMOR-TARGETING NOVEL PEPTIDE IDENTIFIED BY PHAGE DISPLAY

STEM-03. NOVEL METASTATIC BRAIN TUMOR TARGETS ISOLATED THROUGH PHAGE DISPLAY BIOPANNING AGAINST BRAIN METASTASIS-INITIATING CELLS

STEM-08. RNA BINDING PROTEIN ZFP36L2 REGULATES GLIOMA STEM CELL MAINTENANCE

STEM-10. SUPER-ENHANCER SCREEN IDENTIFIES LIPID METABOLISM AS A CANCER STEM CELL DEPENDENCY IN GLIOBLASTOMA

STEM-12. TARGETING GLIOMA STEM CELL MIRNA NETWORKS

scientific article published on 6 November 2017

STEM-12FATE OF BEVACIZUMAB IN GLIOBLASTOMA.

scientific article published on 9 November 2015

STEM-13. IDENTIFICATION OF NOVEL TARGETS IN GLIOBLASTOMA STEM CELLS THROUGH CRISPR-Cas9 SCREENING

STEM-14. RSAD1 IS A NOVEL TARGET IMPLICATED IN THE GLIOBLASTOMA STEM CELL STRESS RESPONSE

scientific article published on 6 November 2017

STEM-15. IDENTIFYING NICHE-INDEPENDENT PRO-TUMORIGENIC FACTORS IN GLIOBLASTOMA

scientific article published on 6 November 2017

STEM-18. RENIN-ANGIOTENSIN SYSTEM IDENTIFIED BY PHAGE DISPLAY SCREENING IS A NEW THERAPEUTIC TARGET FOR GLIOBLASTOMA AND REGULATES PROLIFERATION OF GLIOBLASTOMA STEM CELLS

scientific article published on 6 November 2017

STEM-21DISRUPTION OF FACILITATES CHROMATIN TRANSCRIPTION (FACT) SYNERGIZES WITH EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) INHIBITION AND PREFERENTIALLY TARGETS GLIOBLASTOMA STEM CELLS.

scientific article

STEM-24. CORE CLOCK GENES REGULATE CANCER STEM CELLS IN BRAIN TUMOR

article published in 2017

STEM-29. LAMINA ORGANIZATION PROMOTES MAINTENANCE OF BRAIN TUMOR INITIATING CELLS IN GLIOMA

scientific article published on 6 November 2017

STEM-36. A TRANSLATIONAL REPRESSION PROGRAM IS ASSOCIATED WITH THE STEM CELL STATE IN GLIOBLASTOMA

STEM-43. GSK3β PROMOTES THE BMX-MEDIATED STAT3 ACTIVATION TO MAINTAIN GLIOBLASTOMA STEM CELLS

SUFU: The Jekyll and Hyde of the Cerebellum

scientific article published on 01 January 2019

Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma

scientific article published on 21 March 2008

Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results.

scientific article published in January 2006

Second messenger systems in human gliomas

scientific article

Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation

scientific article

Seeing is Believing: Are Cancer Stem Cells the Loch Ness Monster of Tumor Biology? ⬇️

scientific article published on June 1, 2011

Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation

scientific article

Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis

scientific article published on 11 April 2019

Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE): A Cluster-Randomized Pragmatic Trial of a Multifactorial Fall Injury Prevention Strategy: Design and Methods.

scientific article published on 14 October 2017

Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis

scientific article published on June 2008

Synthesis and Preliminary Evaluation of n.c.a. Iodoquine: A Novel Radiotracer with High Uptake in Cells with High ALDH1 Expression ⬇️

scientific article published on January 1, 2012

TMOD-16. MODELING GLIOBLASTOMA THROUGH CANCER STEM CELL ORGANOIDS

scientific article published on 6 November 2017

TMOD-34. DNA HELICASES HELB AND ATRX MAINTAIN GLIOMA STEM CELLS

TRP-ing up brain tumors ⬇️

scientific article published on August 1, 2012

Targeting A20 decreases glioma stem cell survival and tumor growth

scientific article

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock

scientific article published on 27 August 2019

Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy

scientific article published in November 2017

Targeting cancer stem cells through L1CAM suppresses glioma growth

scientific article published on August 2008

Targeting glioma stem cells through combined BMI1 and EZH2 inhibition

scientific article published on 9 October 2017

Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

scientific article

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells

scientific article published on 01 August 2019

Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells

scientific article published on 14 October 2016

The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells

scientific article published on 27 July 2016

The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina

scientific article

The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies

scientific article published on 23 July 2020

The Quest for Self-Identity: Not All Cancer Stem Cells Are the Same ⬇️

scientific article published on June 18, 2012

The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells

scientific article published on 06 October 2020

The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion

scientific article published on 31 August 2007

The emerging role of anti-angiogenic therapy for malignant glioma

scientific article published on 07 February 2008

The evolving landscape of glioblastoma stem cells

scientific article

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

scientific article

The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma.

scientific article published in September 2015

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

scientific article

The tailless root of glioma: cancer stem cells

scientific article published on August 2014

The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells

scientific article

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

scientific article published on 20 December 2017

Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions

scientific article published on 04 June 2020

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

scientific article

Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value

scientific article published on 24 August 2017

Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan

scientific article published on January 2008

Tumor cells upregulate normoxic HIF-1α in response to doxorubicin

scientific article published on 19 August 2013

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

scientific article

Turning cancer stem cells inside out: an exploration of glioma stem cell signaling pathways

scientific article published on 13 March 2009

Twisted tango: brain tumor neurovascular interactions

scientific article

Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing

scientific article published on 23 January 2020

Using a stem cell-based signature to guide therapeutic selection in cancer

scientific article

Vandetanib, a novel multitargeted kinase inhibitor, in cancer therapy

scientific article published on October 2006

ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors

scientific article published on November 2005

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis

scientific article published on 16 January 2020

Zika virus has oncolytic activity against glioblastoma stem cells

scientific article published on 5 September 2017

Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose

scientific article published on 16 December 2020

Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade

scientific article published on 24 November 2020

c-Myc is required for maintenance of glioma cancer stem cells

scientific article

miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma

scientific article published on 24 December 2013

β-Catenin/POU5F1/SOX2 Transcription Factor Complex Mediates IGF-I Receptor Signaling and Predicts Poor Prognosis in Lung Adenocarcinoma ⬇️

scientific article published on March 28, 2013

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