List of works - Claude Shuttleworth

A novel nerve-muscle preparation, the inter-taenial longitudinal muscle of the guinea pig caecum

Action potential-dependent calcium transients in myenteric S neurons of the guinea-pig ileum

scientific article published in January 1999

Activation of delayed rectifier potassium channels in canine proximal colon by vasoactive intestinal peptide

scientific article

Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices

scientific article

Ca2+ signaling in gerbil CA3 hippocampal neurons following transient in vivo ischemia

scientific article published on 01 June 2000

Caffeine releasable stores of Ca2+ show depletion prior to the final steps in delayed CA1 neuronal death

scientific article

Calcium-dependent NMDA-induced dendritic injury and MAP2 loss in acute hippocampal slices

scientific article published on 17 January 2007

Cerebral Perfusion Effects of Cognitive Training and Transcranial Direct Current Stimulation in Mild-Moderate TBI

scientific article published on 07 October 2020

Characterization of activity-dependent changes in flavoprotein fluorescence in cerebellar slices from juvenile rats.

scientific article

Characterization of inhibitory GABA-A receptor activation during spreading depolarization in brain slice

scientific article

Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance

scientific article published on 04 August 2014

Comparison of the presence and actions of substance P and neurokinin A in guinea-pig taenia coli.

scientific article

Constraining Land Surface and Atmospheric Parameters of a Locally Coupled Model Using Observational Data

article

Contribution of Na(+)/Ca(2+) exchange to excessive Ca(2+) loading in dendrites and somata of CA1 neurons in acute slice

scientific article

Contributions of Ca2+ and Zn2+ to spreading depression-like events and neuronal injury

scientific article published on May 2009

Cortical spreading depression occurs during elective neurosurgical procedures

scientific article published on 11 March 2016

Direct current electrocorticography for clinical neuromonitoring of spreading depolarizations

scientific article published on 10 June 2016

Direct visualization of trapped erythrocytes in rat brain after focal ischemia and reperfusion

scientific article

Dorsal root ganglion neurons of embryonic chicks contain nitric oxide synthase and respond to nitric oxide ⬇️

scientific article published on June 20, 1994

Effect of Locally Delivered Nimodipine Microparticles on Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage

scientific article published on 26 February 2020

Effect of chronic morphine administration on measured levels and chromatographic characterization of six neuropeptides in guinea-pig ileum

scientific article

Effects of a novel guanylate cyclase inhibitor on nitric oxide-dependent inhibitory neurotransmission in canine proximal colon

scientific article

Emergence of a spermine-sensitive, non-inactivating conductance in mature hippocampal CA1 pyramidal neurons upon reduction of extracellular Ca2+: dependence on intracellular Mg2+ and ATP.

scientific article published on 7 September 2006

Evidence that adenosine contributes to Leao's spreading depression in vivo

scientific article published on 23 May 2016

Evidence that nitric oxide acts as an inhibitory neurotransmitter supplying taenia from the guinea-pig caecum

scientific article published on July 1999

Evidence that nitric oxide participates in non-adrenergic inhibitory transmission to intestinal muscle in the guinea-pig.

scientific article published in September 1991

Exploring parameter sensitivities of the land surface using a locally coupled land-atmosphere model

article

GABAergic protection of hippocampal pyramidal neurons against glutamate insult: deficit in young animals compared to adults

scientific article

Hypoxia limits inhibitory effects of Zn2+ on spreading depolarizations

scientific article

Identification of interstitial cells in canine proximal colon using NADH diaphorase histochemistry ⬇️

scientific article published on 01 May 1993

Immunohistochemical localization of 3',5'-cyclic guanosine monophosphate in the canine proximal colon: responses to nitric oxide and electrical stimulation of enteric inhibitory neurons

scientific article published on September 1993

Incidence, hemodynamic, and electrical characteristics of spreading depolarization in a swine model are affected by local but not by intravenous application of magnesium

scientific article published on 28 September 2016

Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia.

scientific article published on January 2009

Intracellular Zn2+ accumulation enhances suppression of synaptic activity following spreading depolarization

scientific article published on 16 April 2013

Intracellular dialysis disrupts Zn2+ dynamics and enables selective detection of Zn2+ influx in brain slice preparations

scientific article published on 22 April 2013

Involvement of nitric oxide in inhibitory neuromuscular transmission in equine jejunum

scientific article published in August 1996

Involvement of nitric oxide in neuromuscular transmission in canine proximal colon

scientific article published on January 1996

Isolation and characterization of resident macrophages from the smooth muscle layers of murine small intestine

scientific article published in February 2004

Ketamine reduces deleterious consequences of spreading depolarizations.

scientific article published on 10 April 2018

Light- and electron-microscopic immunochemical analysis of nerve fibre types innervating the taenia of the guinea-pig caecum.

scientific article published in October 1992

Localized loss of Ca2+ homeostasis in neuronal dendrites is a downstream consequence of metabolic compromise during extended NMDA exposures

scientific article published on May 2008

Microtubule disruption, not calpain-dependent loss of MAP2, contributes to enduring NMDA-induced dendritic dysfunction in acute hippocampal slices

scientific article published on 10 August 2006

Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury?

scientific article

NAD(P)H Fluorescence Imaging of Postsynaptic Neuronal Activation in Murine Hippocampal Slices ⬇️

scientific article published on April 15, 2003

NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function

scientific article published on 15 March 2006

NADPH diaphorase and nitric oxide synthase colocalization in enteric neurons of canine proximal colon

scientific article published on August 1, 1992

Nimodipine Reappraised: An Old Drug With a Future

scientific article published on 01 January 2020

Non-canonical glutamate signaling in a genetic model of migraine with aura

scientific article published on 12 December 2020

Rebound excitation and alternating slow wave patterns depend upon eicosanoid production in canine proximal colon.

scientific article

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.

scientific article published on 17 June 2016

Recycling of L-citrulline to sustain nitric oxide-dependent enteric neurotransmission

scientific article published on 01 October 1995

Regulation of citrulline recycling in nitric oxide-dependent neurotransmission in the murine proximal colon

scientific article

Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission

scientific article published on 01 November 1994

Release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brain

scientific article

Role of Ca(2+)-activated K+ channels in electrical activity of longitudinal and circular muscle layers of canine colon.

scientific article

Roles of peptides in enteric neuromuscular transmission

scientific article published on April 1995

Spreading Depolarizations Occur in Mild Traumatic Brain Injuries and Are Associated with Postinjury Behavior

scientific article published on 01 November 2019

Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial

scientific article published on 25 May 2018

Spreading depolarization may represent a novel mechanism for delayed fluctuating neurological deficit after chronic subdural hematoma evacuation

scientific article published on 27 March 2020

Spreading depolarization-induced adenosine accumulation reflects metabolic status in vitro and in vivo

scientific article published on 27 August 2014

Spreading depression and related events are significant sources of neuronal Zn2+ release and accumulation ⬇️

scientific article published on October 27, 2010

Spreading depression: evidence of five electroencephalogram phases

scientific article

Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons.

scientific article published in June 2001

Suppression of spreading depolarization and stabilization of dendritic spines by GLYX-13, an NMDA receptor glycine-site functional partial agonist

scientific article published on 2 August 2015

Synaptic release and extracellular actions of Zn2+ limit propagation of spreading depression and related events in vitro and in vivo

scientific article published on 30 November 2011

Tachykinins activate nonselective cation currents in canine colonic myocytes

scientific article published on 01 December 1995

Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report

scientific article published on 01 December 2018

The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy

scientific article published on 21 June 2016

The role of the t-SNARE SNAP-25 in action potential-dependent calcium signaling and expression in GABAergic and glutamatergic neurons

scientific article

Topographical and electrophysiological characteristics of highly excitable S neurones in the myenteric plexus of the guinea-pig ileum

scientific article published in June 1999

Use of NAD(P)H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation

scientific article published on 29 December 2009

Vascular, electrophysiological, and metabolic consequences of cortical spreading depression in a mouse model of simulated neurosurgical conditions

scientific article published on March 2012

What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient?

scientific article published on 01 February 2020

Which Spreading Depolarizations Are Deleterious To Brain Tissue?

scientific article published on 01 February 2020

Zinc: new clues to diverse roles in brain ischemia

scientific article published on 27 May 2011

Zn2+-dependent Activation of the Trk Signaling Pathway Induces Phosphorylation of the Brain-enriched Tyrosine Phosphatase STEP: MOLECULAR BASIS FOR ZN2+-INDUCED ERK MAPK ACTIVATION.

scientific article

Zn²+ chelation improves recovery by delaying spreading depression-like events

scientific article

List of works by Claude Shuttleworth

A novel nerve-muscle preparation, the inter-taenial longitudinal muscle of the guinea pig caecum

Action potential-dependent calcium transients in myenteric S neurons of the guinea-pig ileum

Activation of delayed rectifier potassium channels in canine proximal colon by vasoactive intestinal peptide

Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices

Ca2+ signaling in gerbil CA3 hippocampal neurons following transient in vivo ischemia

Caffeine releasable stores of Ca2+ show depletion prior to the final steps in delayed CA1 neuronal death

Calcium-dependent NMDA-induced dendritic injury and MAP2 loss in acute hippocampal slices

Cerebral Perfusion Effects of Cognitive Training and Transcranial Direct Current Stimulation in Mild-Moderate TBI

Characterization of activity-dependent changes in flavoprotein fluorescence in cerebellar slices from juvenile rats.

Characterization of inhibitory GABA-A receptor activation during spreading depolarization in brain slice

Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance

Comparison of the presence and actions of substance P and neurokinin A in guinea-pig taenia coli.

Constraining Land Surface and Atmospheric Parameters of a Locally Coupled Model Using Observational Data

Contribution of Na(+)/Ca(2+) exchange to excessive Ca(2+) loading in dendrites and somata of CA1 neurons in acute slice

Contributions of Ca2+ and Zn2+ to spreading depression-like events and neuronal injury

Cortical spreading depression occurs during elective neurosurgical procedures

Direct current electrocorticography for clinical neuromonitoring of spreading depolarizations

Direct visualization of trapped erythrocytes in rat brain after focal ischemia and reperfusion

Dorsal root ganglion neurons of embryonic chicks contain nitric oxide synthase and respond to nitric oxide ⬇️

Effect of Locally Delivered Nimodipine Microparticles on Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage

Effect of chronic morphine administration on measured levels and chromatographic characterization of six neuropeptides in guinea-pig ileum

Effects of a novel guanylate cyclase inhibitor on nitric oxide-dependent inhibitory neurotransmission in canine proximal colon

Emergence of a spermine-sensitive, non-inactivating conductance in mature hippocampal CA1 pyramidal neurons upon reduction of extracellular Ca2+: dependence on intracellular Mg2+ and ATP.

Evidence that adenosine contributes to Leao's spreading depression in vivo

Evidence that nitric oxide acts as an inhibitory neurotransmitter supplying taenia from the guinea-pig caecum

Evidence that nitric oxide participates in non-adrenergic inhibitory transmission to intestinal muscle in the guinea-pig.

Exploring parameter sensitivities of the land surface using a locally coupled land-atmosphere model

GABAergic protection of hippocampal pyramidal neurons against glutamate insult: deficit in young animals compared to adults

Hypoxia limits inhibitory effects of Zn2+ on spreading depolarizations

Identification of interstitial cells in canine proximal colon using NADH diaphorase histochemistry ⬇️

Immunohistochemical localization of 3',5'-cyclic guanosine monophosphate in the canine proximal colon: responses to nitric oxide and electrical stimulation of enteric inhibitory neurons

Incidence, hemodynamic, and electrical characteristics of spreading depolarization in a swine model are affected by local but not by intravenous application of magnesium

Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia.

Intracellular Zn2+ accumulation enhances suppression of synaptic activity following spreading depolarization

Intracellular dialysis disrupts Zn2+ dynamics and enables selective detection of Zn2+ influx in brain slice preparations

Involvement of nitric oxide in inhibitory neuromuscular transmission in equine jejunum

Involvement of nitric oxide in neuromuscular transmission in canine proximal colon

Isolation and characterization of resident macrophages from the smooth muscle layers of murine small intestine

Ketamine reduces deleterious consequences of spreading depolarizations.

Light- and electron-microscopic immunochemical analysis of nerve fibre types innervating the taenia of the guinea-pig caecum.

Localized loss of Ca2+ homeostasis in neuronal dendrites is a downstream consequence of metabolic compromise during extended NMDA exposures

Microtubule disruption, not calpain-dependent loss of MAP2, contributes to enduring NMDA-induced dendritic dysfunction in acute hippocampal slices

Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury?

NAD(P)H Fluorescence Imaging of Postsynaptic Neuronal Activation in Murine Hippocampal Slices ⬇️

NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function

NADPH diaphorase and nitric oxide synthase colocalization in enteric neurons of canine proximal colon

Nimodipine Reappraised: An Old Drug With a Future

Non-canonical glutamate signaling in a genetic model of migraine with aura

Rebound excitation and alternating slow wave patterns depend upon eicosanoid production in canine proximal colon.

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.

Recycling of L-citrulline to sustain nitric oxide-dependent enteric neurotransmission

Regulation of citrulline recycling in nitric oxide-dependent neurotransmission in the murine proximal colon

Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission

Release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brain

Role of Ca(2+)-activated K+ channels in electrical activity of longitudinal and circular muscle layers of canine colon.

Roles of peptides in enteric neuromuscular transmission

Spreading Depolarizations Occur in Mild Traumatic Brain Injuries and Are Associated with Postinjury Behavior

Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial

Spreading depolarization may represent a novel mechanism for delayed fluctuating neurological deficit after chronic subdural hematoma evacuation

Spreading depolarization-induced adenosine accumulation reflects metabolic status in vitro and in vivo

Spreading depression and related events are significant sources of neuronal Zn2+ release and accumulation ⬇️

Spreading depression: evidence of five electroencephalogram phases

Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons.

Suppression of spreading depolarization and stabilization of dendritic spines by GLYX-13, an NMDA receptor glycine-site functional partial agonist

Synaptic release and extracellular actions of Zn2+ limit propagation of spreading depression and related events in vitro and in vivo

Tachykinins activate nonselective cation currents in canine colonic myocytes

Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report

The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy

The role of the t-SNARE SNAP-25 in action potential-dependent calcium signaling and expression in GABAergic and glutamatergic neurons

Topographical and electrophysiological characteristics of highly excitable S neurones in the myenteric plexus of the guinea-pig ileum

Use of NAD(P)H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation

Vascular, electrophysiological, and metabolic consequences of cortical spreading depression in a mouse model of simulated neurosurgical conditions

What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient?

Which Spreading Depolarizations Are Deleterious To Brain Tissue?

Zinc: new clues to diverse roles in brain ischemia

Zn2+-dependent Activation of the Trk Signaling Pathway Induces Phosphorylation of the Brain-enriched Tyrosine Phosphatase STEP: MOLECULAR BASIS FOR ZN2+-INDUCED ERK MAPK ACTIVATION.

Zn²+ chelation improves recovery by delaying spreading depression-like events