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List of works by Alexandre Barbosa Reis

A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden

scientific article published on 07 March 2017

A killed Leishmania vaccine with sand fly saliva extract and saponin adjuvant displays immunogenicity in dogs.

scientific article published on 17 December 2007

A multicentric evaluation of the recombinant Leishmania infantum antigen-based immunochromatographic assay for the serodiagnosis of canine visceral leishmaniasis.

scientific article

Analysis using canine peripheral blood for establishing in vitro conditions for monocyte differentiation into macrophages for Leishmania chagasi infection and T-cell subset purification

scientific article published on 22 August 2013

Antigenicity of a whole parasite vaccine as promising candidate against canine leishmaniasis

scientific article published on 22 October 2007

Association between mast cells, tissue remodelation and parasite burden in the skin of dogs with visceral leishmaniasis.

scientific article published on 9 July 2017

Autochthonous canine visceral leishmaniasis in a non-endemic area: Bom Sucesso, Minas Gerais State, Brazil

scientific article

Canine visceral leishmaniasis biomarkers and their employment in vaccines

scientific article published on 20 May 2019

Canine visceral leishmaniasis: incidence and risk factors for infection in a cohort study in Brazil.

scientific article published on 30 July 2013

Canine visceral leishmaniasis: performance of a rapid diagnostic test (Kalazar Detect) in dogs with and without signs of the disease

scientific article

Cell recruitment and cytokines in skin mice sensitized with the vaccine adjuvants: saponin, incomplete Freund's adjuvant, and monophosphoryl lipid A

scientific article

Cellular immunophenotypic profile in the splenic compartment during canine visceral leishmaniasis.

scientific article published on 28 November 2013

Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T Cells That Trigger Protection against Experimental Visceral Leishmaniasis

scientific article published on 27 May 2020

Clinical forms of canine visceral Leishmaniasis in naturally Leishmania infantum-infected dogs and related myelogram and hemogram changes

scientific article

Clinical value of anti-Leishmania (Leishmania) chagasi IgG titers detected by flow cytometry to distinguish infected from vaccinated dogs.

scientific article

Clinical, hematological and biochemical alterations in hamster (Mesocricetus auratus) experimentally infected with Leishmania infantum through different routes of inoculation.

scientific article published on 31 March 2016

Cytokine and nitric oxide patterns in dogs immunized with LBSap vaccine, before and after experimental challenge with Leishmania chagasi plus saliva of Lutzomyia longipalpis.

scientific article

Cytokine and transcription factor profiles in the skin of dogs naturally infected by Leishmania (Leishmania) chagasi presenting distinct cutaneous parasite density and clinical status

scientific article published on 19 November 2010

Different infective forms trigger distinct immune response in experimental Chagas disease

scientific article

Dogs immunized with LBSap vaccine displayed high levels of IL-12 and IL-10 cytokines and CCL4, CCL5 and CXCL8 chemokines in the dermis.

scientific article

Effect of the preservative and temperature conditions on the stability of Leishmania infantum promastigotes antigens applied in a flow cytometry diagnostic method for canine visceral leishmaniasis.

scientific article published on 29 May 2013

Effect on cellular recruitment and the innate immune response by combining saponin, monophosphoryl lipid-A and Incomplete Freund's Adjuvant with Leishmania (Viannia) braziliensis antigens for a vaccine formulation

scientific article published on 28 September 2019

Evaluation of a prototype flow cytometry test for serodiagnosis of canine visceral leishmaniasis

scientific article published on 09 October 2013

Evaluation of change in canine diagnosis protocol adopted by the visceral leishmaniasis control program in Brazil and a new proposal for diagnosis.

scientific article

First description of autochthonous canine visceral leishmaniasis in the metropolitan region of Vitória, State of Espírito Santo, Brazil

scientific article published on December 2012

Genetic homogeneity among Leishmania (Leishmania) infantum isolates from dog and human samples in Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil

scientific article published on 15 April 2015

Heading back into the perfect storm: increasing risks for disease emergence in Brazil?

scientific article published in January 2022

Higher expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 chemokines in the skin associated with parasite density in canine visceral leishmaniasis

scientific article

Histological study of cell migration in the dermis of hamsters after immunisation with two different vaccines against visceral leishmaniasis.

scientific article published on 3 December 2008

Histopathological and immunohistochemical investigations of the hepatic compartment associated with parasitism and serum biochemical changes in canine visceral leishmaniasis

scientific article published on 29 June 2007

Histopathology, parasite density and cell phenotypes of the popliteal lymph node in canine visceral leishmaniasis

scientific article published on 25 July 2007

Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR

scientific article

Immunogenicity of a killed Leishmania vaccine with saponin adjuvant in dogs

scientific article published on 24 August 2007

Immunological profile of resistance and susceptibility in naturally infected dogs by Leishmania infantum.

scientific article published on 6 September 2014

Immunotherapy and Immunochemotherapy in Visceral Leishmaniasis: Promising Treatments for this Neglected Disease.

scientific article

Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.

scientific article

Impact of dose and surface features on plasmatic and liver concentrations of biodegradable polymeric nanocapsules

scientific article published on 22 April 2017

In vitro Infectivity of Strains Isolated From Dogs Naturally Infected With Leishmania infantum Present a Distinct Pathogenic Profile in Hamsters

scientific article published on 28 August 2020

Influence of Clinical Status and Parasite Load on Erythropoiesis and Leucopoiesis in Dogs Naturally Infected with Leishmania (Leishmania) chagasi ⬇️

scientific article published on May 10, 2011

Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes

scientific article published on 02 December 2020

LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4⁺ and CD8⁺) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis.

scientific article published on 07 February 2014

Liver infusion tryptose (LIT): the best choice for growth, viability, and infectivity of Leishmania infantum parasites

scientific article published on 09 October 2020

MIXED FORMULATION OF CONVENTIONAL AND PEGYLATED MEGLUMINE ANTIMONIATE-CONTAINING LIPOSOMES REDUCES INFLAMMATORY PROCESS AND PARASITE BURDEN IN L. infantum INFECTED BALB/c MICE.

scientific article published on 21 August 2017

Molecular diagnosis of canine visceral leishmaniasis: a comparative study of three methods using skin and spleen from dogs with natural Leishmania infantum infection

scientific article

Multicomponent LBSap vaccine displays immunological and parasitological profiles similar to those of Leish-Tec® and Leishmune® vaccines against visceral leishmaniasis.

scientific article published on 30 August 2016

Multiplex flow cytometry serology to diagnosis of canine visceral leishmaniasis

scientific article published on 06 August 2019

Neutrophil properties in healthy and Leishmania infantum-naturally infected dogs

scientific article published on 18 April 2019

Novel recombinant multiepitope proteins for the diagnosis of asymptomatic leishmania infantum-infected dogs

scientific article published on 8 January 2015

Parasite burden in hamsters infected with two different strains of leishmania (Leishmania) infantum: "Leishman Donovan units" versus real-time PCR.

scientific article

Performance of LBSap vaccine after intradermal challenge with L. infantum and saliva of Lu. longipalpis: immunogenicity and parasitological evaluation

scientific article

Phase I and II Clinical Trial Comparing the LBSap, Leishmune®, and Leish-Tec® Vaccines against Canine Visceral Leishmaniasis

scientific article published on 17 November 2020

Prevalence and factors associated with Leishmania infantum infection of dogs from an urban area of Brazil as identified by molecular methods

scientific article

Prognostic factors and scoring system for death from visceral leishmaniasis: an historical cohort study in Brazil.

scientific article

Qualitative and quantitative immunohistochemical evaluation of iNOS expression in the spleen of dogs naturally infected with Leishmania chagasi

scientific article published on 29 December 2010

Recent advances and new strategies in Leishmaniasis diagnosis

scientific article published on 26 August 2020

Recent advances and new strategies on leishmaniasis treatment

scientific article published on 02 September 2020

Relationship of Leishmania-specific IgG levels and IgG avidity with parasite density and clinical signs in canine leishmaniasis

scientific article published on 25 January 2010

Risk factors for seroconversion by Leishmania infantum in a cohort of dogs from an endemic area of Brazil

scientific article

Risk profile for Leishmania infection in dogs coming from an area of visceral leishmaniasis reemergence.

scientific article published on 27 November 2017

Serological screening confirms the re-emergence of canine leishmaniosis in urban and rural areas in Governador Valadares, Vale do Rio Doce, Minas Gerais, Brazil.

scientific article

Setting the proportion of CD4+ and CD8+ T-cells co-cultured with canine macrophages infected with Leishmania chagasi

scientific article published on 3 June 2015

Severe airport sanitarian control could slow down the spreading of COVID-19 pandemics in Brazil

scientific article (preprint)

Severe airport sanitarian control could slow down the spreading of COVID-19 pandemics in Brazil

scientific article published on 25 June 2020

Shotgun proteomics to unravel the complexity of the Leishmania infantum exoproteome and the relative abundance of its constituents

scientific article

Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice

scientific article published on 28 October 2019

Systemic and compartmentalized immune response in canine visceral leishmaniasis

scientific article published on 17 October 2008

TcI, TcII and TcVI Trypanosoma cruzi samples from Chagas disease patients with distinct clinical forms and critical analysis of in vitro and in vivo behavior, response to treatment and infection evolution in murine model.

scientific article

The TcI and TcII Trypanosoma cruzi experimental infections induce distinct immune responses and cardiac fibrosis in dogs

scientific article published on December 2014

Trypanosoma cruzi: Serum levels of nitric oxide and expression of inducible nitric oxide synthase in myocardium and spleen of dogs in the acute stage of infection with metacyclic or blood trypomastigotes

scientific article published on 18 October 2008

Worldwide COVID-19 spreading explained: traveling numbers as a primary driver for the pandemic

scientific article published on 16 September 2020

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