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List of works by Jan Starý

A homozygous deletion in the SLC19A1 gene as a cause of folate-dependent recurrent megaloblastic anemia

scientific article published on 10 April 2020

A novel recurrent chromosomal aberration involving chromosome 7 in childhood myelodysplastic syndrome

scientific article published on 01 August 2010

A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial

scientific article published in July 2007

Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome.

scientific article

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin.

scientific article published on October 2010

Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance

scientific article published on 2 March 2017

Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia

scientific article published on 11 February 2009

Allogeneic stem cell transplantation in children with leukemia using human leukocyte antigen-mismatched unrelated donors

scientific article published on 01 February 2008

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement.

scientific article published on 24 October 2014

Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study

scientific article published on 31 January 2019

BCOR and BCORL1 mutations in pediatric acute myeloid leukemia

scientific article published on 16 January 2015

Blast clearance after one week of corticosteroids correlates with outcome and genetics but does not justify adding a residual disease time point in acute lymphoblastic leukemia treatment

scientific article published on 29 October 2020

Bone marrow transplantation for inherited bone marrow failure syndromes

scientific article published on February 2010

CBLmutations do not frequently occur in paediatric acute myeloid leukaemia

article

Characterization of leukemias with ETV6-ABL1 fusion

scientific article published on 26 May 2016

Chemotherapy versus allogeneic transplantation for very-high-risk childhood acute lymphoblastic leukaemia in first complete remission: comparison by genetic randomisation in an international prospective study

scientific article published in August 2005

Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation

scientific article published on 24 February 2020

CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out

scientific article published on 01 January 2020

Clinical Implications of Minimal Residual Disease Detection in Infants With <i>KMT2A</i>-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

scientific article published on 06 January 2021

Clofarabine, high-dose cytarabine and liposomal daunorubicin in pediatric relapsed/refractory acute myeloid leukemia: a phase IB study

scientific article published on 17 May 2018

Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia

scientific article published on 31 October 2012

Comparison of horse and rabbit antithymocyte globulin in immunosuppressive therapy for refractory cytopenia of childhood

scientific article published on 25 October 2013

Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome

scientific article published on 27 August 2010

Covert preleukemia driven by MLL gene fusion

scientific article published in January 2009

Cytometric analysis of cell suspension generated by cavitron ultrasonic surgical aspirator in pediatric brain tumors

scientific article published on 02 March 2019

DUX4r, ZNF384r and PAX5-P80R mutated B-cell precursor acute lymphoblastic leukemia frequently undergo monocytic switch

scientific article published on 09 July 2020

Development of the Czech Childhood Cancer Information System: Data Analysis and Interactive Visualization

scientific article published on 29 June 2021

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

scientific article published on 09 August 2012

Distinct bilineal leukemia immunophenotypes are not genetically determined

scientific article published on 13 September 2016

ERG deletions in childhood acute lymphoblastic leukemia with DUX4 rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on screening method sensitivity

scientific article published on 10 January 2019

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

scientific article published on 10 April 2017

Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukemia: analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98.

scientific article

Eligibility for allogeneic transplantation in very high risk childhood acute lymphoblastic leukemia: the impact of the waiting time

scientific article published on 15 April 2008

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

scientific article

Exchange Transfusion and Leukapheresis in Pediatric Patients with AML With High Risk of Early Death by Bleeding and Leukostasis

scientific article published on 16 December 2015

Fanconi anemia with biallelic FANCD1/BRCA2 mutations - Case report of a family with three affected children

scientific article

Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses

scientific article published on 8 March 2010

Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment

scientific article published on 07 April 2020

Frequency and prognostic impact of ZEB2 H1038 and 1072 mutations in childhood B-other acute lymphoblastic leukemia

scientific article published on 04 June 2020

Gene Expression–Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia

scientific article published on 15 March 2010

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort

scientific article published on 10 January 2019

Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse

scientific article

Granulocyte transfusions in children and young adults: does the dose matter?

scientific article published on March 2009

Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial.

scientific article published on 7 September 2004

High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).

scientific article published on 2 November 2010

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations

scientific article

Identification of Fusion Gene Breakpoints is Feasible and Facilitates Accurate Sensitive Minimal Residual Disease Monitoring on Genomic Level in Patients With PML-RARA, CBFB-MYH11, and RUNX1-RUNX1T1

scientific article published on 10 November 2020

Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond-Blackfan anemia

scientific article

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL‐negative acute lymphoblastic leukemia

scientific article published on September 19, 2012

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

scientific article

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial

scientific article published on 01 December 2018

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia

scientific article

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study

scientific article published on 30 June 2010

Increased proportions of γδ T lymphocytes in atypical SCID associate with disease manifestations

scientific article published on 15 February 2019

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

scientific article

Intensive chemotherapy for childhood acute lymphoblastic leukemia: results of the randomized intercontinental trial ALL IC-BFM 2002.

scientific article published on 16 December 2013

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

scientific article published on 2 May 2018

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

scientific article

Jumping translocations in bone marrow cells of pediatric patients with hematologic malignancies: a rare cytogenetic phenomenon

scientific article published on 01 June 2011

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

scientific article published on 11 March 2016

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

scientific article published on 28 December 2015

Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.

scientific article published on September 2006

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

scholarly article by Andrea Biondi et al published January 2019 in Haematologica

Long-term treatment results of Polish pediatric and adolescent patients enrolled in the ALL IC-BFM 2002 trial

scientific article published on 30 August 2019

Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique.

scientific article published on 16 March 2010

MEDU-41. MANAGEMENT OF MEDULLOBLASTOMA PATIENTS IN PRAGUE PEDIATRIC HEMATOLOGY AND ONCOLOGY CENTER.

scientific article published on 31 May 2017

Mapping epigenetic regulator gene mutations in cytogenetically normal pediatric acute myeloid leukemia

scientific article published on 9 May 2014

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

scientific article published on 05 June 2020

Minimal residual disease in peripheral blood at day 15 identifies a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis

scientific article published on August 31, 2011

Mitotic recombination and compound-heterozygous mutations are predominant NF1-inactivating mechanisms in children with juvenile myelomonocytic leukemia and neurofibromatosis type 1.

scientific article

Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology.

scientific article published on 22 March 2017

Most pediatric patients with essential thrombocythemia show hypersensitivity to erythropoietin in vitro, with rare JAK2 V617F-positive erythroid colonies

scientific article published on 23 August 2007

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia

scientific article published on July 2009

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 28 September 2018

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.

scientific article

Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study

scientific article published on 18 January 2019

Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study

scientific article published on 08 July 2019

Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.

scientific article

Pharmacokinetics of daunorubicin and daunorubicinol in infants with leukemia treated in the interfant 99 protocol

scientific article published on 01 March 2010

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

scientific article published in May 2009

Phase I dose-escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors

scientific article published on 05 July 2019

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic l

scholarly article by Giovanni Cazzaniga et al published January 2018 in Haematologica

Prenatal origin of childhood AML occurs less frequently than in childhood ALL.

scientific article published on 21 April 2006

Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria

scientific article published on 9 February 2010

Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.

scientific article

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group

scientific article published on 27 August 2018

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study

scientific article

Prognostic value of structural chromosomal rearrangements and small cell clones with high hyperdiploidy in children with acute lymphoblastic leukemia

scientific article published on 01 March 2005

Prophylactic human granulocyte colony-stimulating factor after induction therapy in pediatric acute myeloid leukemia

scientific article published on 28 September 2006

Pulses of vincristine and dexamethasone in addition to intensive chemotherapy for children with intermediate-risk acute lymphoblastic leukaemia: a multicentre randomised trial

scientific article published on January 2007

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

scientific article published on 19 December 2017

Rapidly progressing acute myeloid leukemia with KAT6A-LEUTX fusion in a newborn

scientific article published on 11 August 2020

Salvage treatment for children with refractory first or second relapse of acute myeloid leukaemia with gemtuzumab ozogamicin: results of a phase II study

scientific article published on 08 December 2009

Second induction with high-dose cytarabine and mitoxantrone: different impact on pediatric AML patients with t(8;21) and with inv(16).

scientific article published on 26 September 2011

Significance of real-time quantitative PCR detection of p16 gene deletions in childhood acute lymphoblastic leukemia

scientific article published on 01 June 2002

Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.

scientific article published on 10 May 2016

Somatic thrombopoietin (THPO) gene mutations in childhood myeloid leukemias

scientific article published on 03 March 2015

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

scientific article published on 11 January 2012

Successful therapy with ABLC, surgery and posaconazole for Rhizopus microsporus var. rhizopodiformis liver eumycetoma in a child with acute leukaemia

scientific article published on 15 July 2008

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases.

scientific article

The Czech National Diamond-Blackfan Anemia Registry: clinical data and ribosomal protein mutations update.

scientific article

The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol.

scientific article published in April 2004

The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia

scientific article published on 07 May 2020

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

scientific article published on 01 June 2018

The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease

scientific article published on 31 May 2005

The predictive strength of next-generation sequencing MRD detection for relapse compared with current methods in childhood ALL.

scientific article published on August 2015

Therapeutic drug monitoring of asparaginase: intra-individual variability and predictivity in children with acute lymphoblastic leukemia treated with PEG-asparaginase in the AIEOP-BFM ALL 2009 study

scientific article published on 14 January 2020

Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis

scientific article published on 13 August 2018

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin

scientific article published on 30 July 2018

Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL

scientific article published on 01 January 2019

Transplantace kostní dřeně a periferních hematopoetických buněk

book edition published in 2016