List of works - Hugo Mouquet

A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations

scientific article published on 17 August 2020

A method for identification of HIV gp140 binding memory B cells in human blood

scientific article

A single cycle of rituximab for the treatment of severe pemphigus.

scientific article

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

scientific article

Amplification of highly mutated human Ig lambda light chains from an HIV-1 infected patient

scientific article published on 7 February 2015

Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity

scientific article

Antibodies in HIV-1 vaccine development and therapy

scientific article

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

scientific article

Antibody B cell responses in HIV-1 infection

scientific article published on 16 September 2014

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

scientific article

Binding mechanisms of therapeutic antibodies to human CD20

scientific article published on 01 August 2020

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

scientific article

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

scientific article

Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission

scientific article

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

scientific article

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

scientific article

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity.

scientific article published in May 2018

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

scientific article published on 24 October 2011

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

scientific article

ELISA testing of anti-desmoglein 1 and 3 antibodies in the management of pemphigus.

scientific article

Early Antiretroviral Therapy Preserves Functional Follicular Helper T and HIV-Specific B Cells in the Gut Mucosa of HIV-1-Infected Individuals.

scientific article

Efficient generation of human IgA monoclonal antibodies

scientific article published on 22 April 2015

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

scientific article

Enhanced HIV-1 neutralization by antibody heteroligation

scientific article published on 4 January 2012

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

scientific article published on 10 August 2009

Genetic factors in pemphigus

scientific article

Genetically intact but functionally impaired HIV-1 Env glycoproteins in the T-cell reservoir.

scientific article published on 29 November 2017

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

scientific article

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

scientific article published on 24 October 2012

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

article

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

scientific article published on 16 September 2013

HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection

scientific article published on 31 May 2017

HIV: Roadmaps to a vaccine

scientific article published on 3 April 2013

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

scientific article

Humanized mouse models to study pathophysiology and treatment of HIV infection

scientific article

Hunting Down the HIV-1 Reservoir: A Starring Role for Antibodies?

scientific article published on April 2017

Immunogenetics of pemphigus: an update

scientific article published on November 2006

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

scientific article

Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies

scientific article published on 25 January 2017

Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

scientific article

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

scientific article published on 21 April 2015

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

scientific article

Polyreactive antibodies in adaptive immune responses to viruses

scientific article

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

scientific article published on September 2010

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

scientific article

Reduced sensitivity of infectious SARS-CoV-2 variant B.1.617.2 to monoclonal antibodies and sera from convalescent and vaccinated individuals

scientific article

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

scientific article published on February 2017

SARS-CoV-2 serological analysis of COVID-19 hospitalized patients, pauci-symptomatic individuals and blood donors.

scientific article published on 24 April 2020

Scarcity of autoreactive human blood IgA+ memory B cells

scientific article

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

scientific article

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

scientific article

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

scientific article published on 12 May 2022

TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice

scientific article published on 30 November 2020

Tailored immunogens for rationally designed antibody-based HIV-1 vaccines

scientific article published on 11 July 2015

The value of open-source clinical science in pandemic response: lessons from ISARIC

scientific article published in 2021

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

scientific article published on 21 September 2015

What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Lessons from the Antibody Response to HIV-1.

scientific article published on 19 June 2017

[CRISPR-Cas9 editing of HIV-1 neutralizing human B cells]

scientific article published on 01 December 2019

List of works by Hugo Mouquet

A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations

A method for identification of HIV gp140 binding memory B cells in human blood

A single cycle of rituximab for the treatment of severe pemphigus.

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Amplification of highly mutated human Ig lambda light chains from an HIV-1 infected patient

Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity

Antibodies in HIV-1 vaccine development and therapy

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

Antibody B cell responses in HIV-1 infection

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

Binding mechanisms of therapeutic antibodies to human CD20

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity.

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

ELISA testing of anti-desmoglein 1 and 3 antibodies in the management of pemphigus.

Early Antiretroviral Therapy Preserves Functional Follicular Helper T and HIV-Specific B Cells in the Gut Mucosa of HIV-1-Infected Individuals.

Efficient generation of human IgA monoclonal antibodies

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

Enhanced HIV-1 neutralization by antibody heteroligation

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

Genetic factors in pemphigus

Genetically intact but functionally impaired HIV-1 Env glycoproteins in the T-cell reservoir.

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection

HIV: Roadmaps to a vaccine

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

Humanized mouse models to study pathophysiology and treatment of HIV infection

Hunting Down the HIV-1 Reservoir: A Starring Role for Antibodies?

Immunogenetics of pemphigus: an update

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies

Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

Polyreactive antibodies in adaptive immune responses to viruses

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

Reduced sensitivity of infectious SARS-CoV-2 variant B.1.617.2 to monoclonal antibodies and sera from convalescent and vaccinated individuals

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

SARS-CoV-2 serological analysis of COVID-19 hospitalized patients, pauci-symptomatic individuals and blood donors.

Scarcity of autoreactive human blood IgA+ memory B cells

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice

Tailored immunogens for rationally designed antibody-based HIV-1 vaccines

The value of open-source clinical science in pandemic response: lessons from ISARIC

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Lessons from the Antibody Response to HIV-1.

[CRISPR-Cas9 editing of HIV-1 neutralizing human B cells]