List of works - Seung-Yong Seo

A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy

scientific article published on December 2008

A novel iNOS and COX-2 inhibitor from the aerial parts of Rodgersia podophylla

scientific article published on 19 June 2006

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy

scientific article published on 5 May 2016

Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte

scientific article published on 23 November 2020

Asymmetric total synthesis of bacillariolide III, a marine oxylipin

scientific article published on 01 February 2004

Chemical Proteomics Reveals Soluble Epoxide Hydrolase as a Therapeutic Target for Ocular Neovascularization

scientific article published in December 2017

CoMFA and CoMSIA 3D QSAR studies on pimarane cyclooxygenase-2 (COX-2) inhibitors

scientific article published on May 2004

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

scientific article published in October 2005

Concise Syntheses of (+)-Macrosphelides A and B

scientific article published on 18 June 2005

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

scientific article

Concise synthesis of rodgersinol and determination of the C-10 absolute configuration

scientific article published on 01 January 2007

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF₁ production

scientific article

Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids.

scientific article

Design, synthesis, and biological evaluation of phenylpropanamides as novel transient receptor potential vanilloid 1 antagonists

scientific article published on 26 September 2009

Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1.

scientific article

Effect of 15-hydroxyprostaglandin dehydrogenase inhibitor on wound healing

scientific article published on 7 April 2015

Enantioselective Synthesis of Homoisoflavanones by Asymmetric Transfer Hydrogenation and Their Biological Evaluation for Antiangiogenic Activity

scientific article published on 05 August 2019

Enantioselective synthesis and absolute configuration determination of hydroxywilfordic acid in sesquiterpene pyridine alkaloids

scientific article published on 01 December 2018

Facile synthesis of hydroxy wilfordic acid, a esterifying unit of anti-HIV sesquiterpene pyridine alkaloids

scientific article published in December 2009

Ferrochelatase is a therapeutic target for ocular neovascularization.

scientific article

Hexane-Soluble Fraction of the Common Fig, Ficus carica, Inhibits Osteoclast Differentiation in Murine Bone Marrow-Derived Macrophages and RAW 264.7 Cells

scientific article

Honokiol ameliorates angiotensin II-induced hypertension and endothelial dysfunction by inhibiting HDAC6-mediated cystathionine γ-lyase degradation

scientific article published on 04 August 2020

Identification and characterization of a peptidic ligand for Ras.

scientific article

Mechanism for increased bioavailability of tacrine in fasted rats

scientific article published in May 2006

Mouse Pharmacokinetics and in Vitro Metabolism of (±)-Cremastranone

scientific article published on 01 January 2019

Multi-targeted hybrids based on HDAC inhibitors for anti-cancer drug discovery

scientific article published on 01 February 2012

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

scientific article published on 09 October 2018

Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents

scientific article

Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells

scientific article published on 23 August 2019

Pharmacokinetics and metabolism of 4-O-methylhonokiol in rats

scientific article published on 3 July 2013

Quantitative determination of a synthetic amide derivative of gallic acid, SG-HQ2, using liquid chromatography tandem mass spectrometry, and its pharmacokinetics in rats

scientific article published on 21 August 2016

SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription

scientific article published on 30 June 2020

SG-HQ2 inhibits mast cell-mediated allergic inflammation through suppression of histamine release and pro-inflammatory cytokines

scientific article published on 27 October 2014

SG-SP1 Suppresses Mast Cell-Mediated Allergic Inflammation via Inhibition of FcεRI Signaling

scientific article published on 28 January 2020

Small molecule target identification using photo-affinity chromatography

scientific article published on 15 March 2019

Small-molecule inhibitors of ferrochelatase are antiangiogenic agents

scientific article

Stereoselective formation of N-acyliminium ion via chiral N,O-acetal TMS ether and its application to the synthesis of beta-amino acids

scientific article published on 01 October 2003

Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

scientific article published on 27 March 2019

Syntheses and anti-MRSA activities of the C3 analogs of mansonone F, a potent anti-bacterial sesquiterpenoid: insights into its structural requirements for anti-MRSA activity

scientific article published in September 2004

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

scientific article published on 16 June 2015

Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs

scientific article published on July 2004

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

scientific article published on 09 November 2018

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis.

scientific article

Synthesis and characterization of G5 PAMAM dendrimer containing daunorubicin for targeting cancer cells

scientific article

Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth

scientific article (publication date: 2014)

Synthesis of Either C2- or C4'-Alkylated Derivatives of Honokiol and Their Biological Evaluation for Anti-inflammatory Activity

scientific article published on 28 June 2019

Synthesis of Gallic Acid Analogs as Histamine and Pro-Inflammatory Cytokine Inhibitors for Treatment of Mast Cell-Mediated Allergic Inflammation.

scientific article published on 29 May 2017

Synthesis of Natural Homoisoflavonoids Having Either 5,7-Dihydroxy-6-methoxy or 7-Hydroxy-5,6-dimethoxy Groups

scientific article published on 13 August 2016

Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.

scientific article published on 25 March 2014

Synthesis, biological evaluation, and metabolic stability of chlorogenic acid derivatives possessing thiazole as potent inhibitors of α-MSH-stimulated melanogenesis

scientific article

The first synthesis of the antiangiogenic homoisoflavanone, cremastranone ⬇️

scientific article

The inhibitory effect of vitexin on the agonist-induced regulation of vascular contractility.

scientific article

The new 4-O-methylhonokiol analog GS12021 inhibits inflammation and macrophage chemotaxis: role of AMP-activated protein kinase α activation.

scientific article

Total Synthesis of Naturally Occurring 5,7,8-Trioxygenated Homoisoflavonoids

scientific article published on 06 May 2020

Total synthesis of (+)-Brefeldin A.

scientific article published in June 2002

Upregulation of both heme oxygenase-1 and ATPase inhibitory factor 1 renders tumoricidal activity by synthetic flavonoids via depleting cellular ATP.

scientific article published on 3 September 2014

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

scientific article published on 31 July 2014

Wound healing effects of new 15-hydroxyprostaglandin dehydrogenase inhibitors

scientific article

δ-Tocopherol prevents methylglyoxal-induced apoptosis by reducing ROS generation and inhibiting apoptotic signaling cascades in human umbilical vein endothelial cells

scientific article

List of works by Seung-Yong Seo

A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy

A novel iNOS and COX-2 inhibitor from the aerial parts of Rodgersia podophylla

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy

Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte

Asymmetric total synthesis of bacillariolide III, a marine oxylipin

Chemical Proteomics Reveals Soluble Epoxide Hydrolase as a Therapeutic Target for Ocular Neovascularization

CoMFA and CoMSIA 3D QSAR studies on pimarane cyclooxygenase-2 (COX-2) inhibitors

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

Concise Syntheses of (+)-Macrosphelides A and B

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

Concise synthesis of rodgersinol and determination of the C-10 absolute configuration

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF₁ production

Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids.

Design, synthesis, and biological evaluation of phenylpropanamides as novel transient receptor potential vanilloid 1 antagonists

Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1.

Effect of 15-hydroxyprostaglandin dehydrogenase inhibitor on wound healing

Enantioselective Synthesis of Homoisoflavanones by Asymmetric Transfer Hydrogenation and Their Biological Evaluation for Antiangiogenic Activity

Enantioselective synthesis and absolute configuration determination of hydroxywilfordic acid in sesquiterpene pyridine alkaloids

Facile synthesis of hydroxy wilfordic acid, a esterifying unit of anti-HIV sesquiterpene pyridine alkaloids

Ferrochelatase is a therapeutic target for ocular neovascularization.

Hexane-Soluble Fraction of the Common Fig, Ficus carica, Inhibits Osteoclast Differentiation in Murine Bone Marrow-Derived Macrophages and RAW 264.7 Cells

Honokiol ameliorates angiotensin II-induced hypertension and endothelial dysfunction by inhibiting HDAC6-mediated cystathionine γ-lyase degradation

Identification and characterization of a peptidic ligand for Ras.

Mechanism for increased bioavailability of tacrine in fasted rats

Mouse Pharmacokinetics and in Vitro Metabolism of (±)-Cremastranone

Multi-targeted hybrids based on HDAC inhibitors for anti-cancer drug discovery

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents

Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells

Pharmacokinetics and metabolism of 4-O-methylhonokiol in rats

Quantitative determination of a synthetic amide derivative of gallic acid, SG-HQ2, using liquid chromatography tandem mass spectrometry, and its pharmacokinetics in rats

SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription

SG-HQ2 inhibits mast cell-mediated allergic inflammation through suppression of histamine release and pro-inflammatory cytokines

SG-SP1 Suppresses Mast Cell-Mediated Allergic Inflammation via Inhibition of FcεRI Signaling

Small molecule target identification using photo-affinity chromatography

Small-molecule inhibitors of ferrochelatase are antiangiogenic agents

Stereoselective formation of N-acyliminium ion via chiral N,O-acetal TMS ether and its application to the synthesis of beta-amino acids

Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

Syntheses and anti-MRSA activities of the C3 analogs of mansonone F, a potent anti-bacterial sesquiterpenoid: insights into its structural requirements for anti-MRSA activity

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis.

Synthesis and characterization of G5 PAMAM dendrimer containing daunorubicin for targeting cancer cells

Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth

Synthesis of Either C2- or C4'-Alkylated Derivatives of Honokiol and Their Biological Evaluation for Anti-inflammatory Activity

Synthesis of Gallic Acid Analogs as Histamine and Pro-Inflammatory Cytokine Inhibitors for Treatment of Mast Cell-Mediated Allergic Inflammation.

Synthesis of Natural Homoisoflavonoids Having Either 5,7-Dihydroxy-6-methoxy or 7-Hydroxy-5,6-dimethoxy Groups

Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.

Synthesis, biological evaluation, and metabolic stability of chlorogenic acid derivatives possessing thiazole as potent inhibitors of α-MSH-stimulated melanogenesis

The first synthesis of the antiangiogenic homoisoflavanone, cremastranone ⬇️

The inhibitory effect of vitexin on the agonist-induced regulation of vascular contractility.

The new 4-O-methylhonokiol analog GS12021 inhibits inflammation and macrophage chemotaxis: role of AMP-activated protein kinase α activation.

Total Synthesis of Naturally Occurring 5,7,8-Trioxygenated Homoisoflavonoids

Total synthesis of (+)-Brefeldin A.

Upregulation of both heme oxygenase-1 and ATPase inhibitory factor 1 renders tumoricidal activity by synthetic flavonoids via depleting cellular ATP.

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

Wound healing effects of new 15-hydroxyprostaglandin dehydrogenase inhibitors

δ-Tocopherol prevents methylglyoxal-induced apoptosis by reducing ROS generation and inhibiting apoptotic signaling cascades in human umbilical vein endothelial cells