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List of works by Keli L Hippen

A robust in vitro model for trans-lymphatic endothelial migration

scientific article

Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.

scientific article published on 21 May 2018

Adoptive Transfer of Umbilical Cord Blood-Derived Regulatory T Cells and Early Viral Reactivation ⬇️

scientific article published on June 25, 2013

Attenuation of IL-7 receptor signaling is not required for allelic exclusion

scientific article published on 01 March 2006

Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity

scientific article published on 19 February 2020

B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements

scientific article

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

scientific article

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes ⬇️

scientific article published on November 10, 2011

CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration

scientific article published on 01 March 2019

CD5 maintains tolerance in anergic B cells

scientific article

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

scientific article

Clinical perspectives for regulatory T cells in transplantation tolerance ⬇️

scientific article published on 05 August 2011

Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol

scientific article published on 03 December 2019

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

scientific article published on 01 November 2019

Differential Regulation of T-cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node

scientific article published on 01 October 2019

Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets

scientific article published on 06 June 2019

Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing

Distinct Regulatory and Effector T Cell Metabolic Demands during Graft-Versus-Host Disease

scientific article published on 30 November 2019

Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease

scientific article published on 31 January 2018

Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases

scientific article published on 27 October 2015

Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc.

scientific article published in June 2004

Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

scientific article published on 12 May 2011

Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions

scientific article

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity

scientific article published on 26 June 2017

ICOSL+ plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist

scientific article published on 01 October 2020

Ig light chain receptor editing in anergic B cells

scientific article published on 01 December 2000

Immune regulatory cells in umbilical cord blood: T regulatory cells and mesenchymal stromal cells

scientific article published on October 2009

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

scientific article

In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance

scientific article published on 01 July 2005

Induction of immunosuppressive functions and NF-κB by FLIP in monocytes

scientific article published in Nature Communications

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics ⬇️

scientific article published on October 15, 2010

Late immature B cells (IgMhighIgDneg) undergo a light chain receptor editing response to soluble self-antigen

scientific article published in July 2003

Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

scientific article published on May 2011

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

scientific article published on 26 December 2019

Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials

scientific article published on 22 November 2016

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

scientific article published on 21 April 2022

Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease

scientific article published in December 2016

Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus

scientific article

Protein kinase C-theta mediates negative feedback on regulatory T cell function

scientific article published on 25 March 2010

Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

scientific article published on 01 January 2020

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

scientific article published on 14 August 2011

Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses

scientific article published on 24 September 2020

Role for Msh5 in the regulation of Ig class switch recombination

scientific article

Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease

scientific article published on 07 March 2019

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

scientific article published on 17 January 2012

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

scientific article

The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation

scientific article published in Nature Communications

The lymph node stromal laminin alpha 5 shapes alloimmunity

scientific article published on 04 February 2020

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8 T cells

scientific article published in Nature

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

Toward revision of antimicrobial therapies in hematopoietic stem cell transplantation: target the pathogens, but protect the indigenous microbiota.

scientific article

Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells.

scientific article published on 7 November 2013

Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration

scientific article

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

scientific article published on 21 July 2008

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

scientific article published on 12 November 2015

Visualization of the genesis and fate of isotype-switched B cells during a primary immune response

scientific article

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg).

scientific article published on 19 February 2018

miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

scientific article published on 2 August 2016

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