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List of works by Kathrin Jansen

13-Valent pneumococcal conjugate vaccine in older children and adolescents either previously immunized with or naïve to 7-valent pneumococcal conjugate vaccine

scientific article published on February 2014

13-valent pneumococcal conjugate vaccine immune sera protects against pneumococcal serotype 1, 3, and 5 bacteremia in a neonatal rat challenge model ⬇️

scientific article published on January 1, 2011

1337. Development, Maintenance, and Application of Opsonophagocytic Assays to Measure Functional Antibody Responses to Support a 20 Valent Pneumococcal Conjugate Vaccine

244. Development, Qualification, and Clinical Validation of an Immunodiagnostic assay for the Detection of 11 Additional S. pneumoniae Serotype-Specific Polysaccharides in Human Urine

2755. Phase 1/2, First-in-Human Study of the Safety, Tolerability, and Immunogenicity of an RSV Prefusion F-Based Subunit Vaccine Candidate

2781. Statistical Modeling to Predict Maternal RSV Vaccine Efficacy from Neutralizing Titers

599Rapid rises in antibody titers observed following single dose administration of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) to healthy adults.

scientific article published in December 2014

A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults

scientific article published in December 2017

A Longitudinal Epidemiology Study of Meningococcal Carriage in Students 13 to 25 Years Old in Quebec

scientific article published in 2018

A Novel Hexavalent Capsular Polysaccharide Conjugate Vaccine (GBS6) for the Prevention of Neonatal Group B Streptococcal Infections by Maternal Immunization.

scientific article published in June 2019

A Phase 2 Study Evaluating the Safety, Tolerability, and Immunogenicity of Two 3-Dose Regimens of a Clostridium difficile Vaccine in Healthy US Adults Aged 65 to 85 Years

scientific article published on 01 January 2020

A Phase 2, Randomized, Active-controlled, Observer-blinded Study to Assess the Immunogenicity, Tolerability and Safety of Bivalent rLP2086, a Meningococcal Serogroup B Vaccine, Coadministered With Tetanus, Diphtheria and Acellular Pertussis Vaccine

scientific article published on 01 June 2016

A Recombinant Clumping Factor A-Containing Vaccine Induces Functional Antibodies to Staphylococcus aureus That Are Not Observed after Natural Exposure ⬇️

scientific article (publication date: October 2012)

A Vaccine Approach for the Prevention of Infections by Multidrug-resistant Enterococcus faecium

scientific article published on 24 June 2015

A controlled trial of a human papillomavirus type 16 vaccine

scientific article published in November 2002

A multi-country evaluation of Neisseria meningitidis serogroup B factor H-binding proteins and implications for vaccine coverage in different age groups

scientific article

A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus macaques and specific increased survival in a murine S. aureus sepsis model

scientific article

A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile.

scientific article published on 29 April 2013

A phase 1 randomized study assessing safety and immunogenicity of two 3-dose regimens of a Clostridium difficile vaccine in healthy older Japanese adults

scientific article published on 05 April 2019

A phase 1, placebo-controlled, randomized study of the safety, tolerability, and immunogenicity of a Clostridium difficile vaccine administered with or without aluminum hydroxide in healthy adults

scientific article

A phase 3, randomized, active-controlled study to assess the safety and tolerability of meningococcal serogroup B vaccine bivalent rLP2086 in healthy adolescents and young adults

scientific article published on February 2016

A phase I study to evaluate a human papillomavirus (HPV) type 18 L1 VLP vaccine

scientific article published on 01 August 2004

A randomized phase I study of the safety and immunogenicity of three ascending dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults.

scientific article published on 21 February 2015

A randomized, controlled, phase 1/2 trial of a Neisseria meningitidis serogroup B bivalent rLP2086 vaccine in healthy children and adolescents

scientific article published on April 2013

A recombinant 63-kDa form of Bacillus anthracis protective antigen produced in the yeast Saccharomyces cerevisiae provides protection in rabbit and primate inhalational challenge models of anthrax infection.

scientific article published on 21 October 2005

Adult vaccination

scientific article

An immunodominant NP<sub>105-113</sub>-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

scientific article published on 01 December 2021

Anti-infective vaccination in the 21st century-new horizons for personal and public health

scientific article

Approach to the Discovery, Development, and Evaluation of a Novel Neisseria meningitidis Serogroup B Vaccine

scientific article

Bactericidal activity of sera from adolescents vaccinated with bivalent rLP2086 against meningococcal serogroup B outbreak strains from France

scientific article published on 10 February 2017

Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease

scientific article published on 07 July 2010

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T-cell responses

scientific article published on 30 September 2020

Capsular polysaccharides are an important immune evasion mechanism forStaphylococcus aureus ⬇️

scientific article published on December 18, 2012

Challenges for the evaluation of Staphylococcus aureus protein based vaccines: Monitoring antigenic diversity ⬇️

scientific article published on 01 January 2011

Coadministration of 13-valent pneumococcal conjugate and quadrivalent inactivated influenza vaccines in adults previously immunized with polysaccharide pneumococcal vaccine 23: a randomized clinical trial

article

Comparison of Phenotypic and Genotypic Approaches to Capsule Typing of Neisseria meningitidis by Use of Invasive and Carriage Isolate Collections ⬇️

scientific article

Concurrent human antibody and TH1 type T-cell responses elicited by a COVID-19 RNA vaccine

preprint

Covering all the Bases: Preclinical Development of an Effective Staphylococcus aureus Vaccine

scientific article

Demonstration of the preclinical correlate of protection for Staphylococcus aureus clumping factor A in a murine model of infection

scientific article published on 26 August 2015

Detection of HPV in Norwegian cervical biopsy specimens with type-specific PCR and reverse line blot assays.

scientific article

Detection of LP2086 on the cell surface of Neisseria meningitidis and its accessibility in the presence of serogroup B capsular polysaccharide

scientific article published on 5 February 2009

Detection of specific human papillomavirus types in paraffin-embedded sections of cervical carcinomas

scientific article published on 01 January 2006

Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to Capsular Polysaccharides

article

Development of a multicomponentStaphylococcus aureusvaccine designed to counter multiple bacterial virulence factors ⬇️

scientific article published on August 24, 2012

Development of a subunit vaccine for prevention of Clostridium difficile associated diseases: Biophysical characterization of toxoids A and B.

scientific article published on 5 January 2017

Diagnostic accuracy of a serotype-specific antigen test in community-acquired pneumonia ⬇️

scientific article published on 08 February 2013

Differences between culture & non-culture confirmed invasive meningococci with a focus on factor H-binding protein distribution

scientific article

Distinct fibroblast subsets drive inflammation and damage in arthritis

scientific article published on 29 May 2019

Dose-ranging studies of the safety and immunogenicity of human papillomavirus Type 11 and Type 16 virus-like particle candidate vaccines in young healthy women

scientific article published in July 2004

Early assessment of the efficacy of a human papillomavirus type 16 L1 virus-like particle vaccine

scientific article published in July 2004

Effect of vaccine delivery system on the induction of HPV16L1-specific humoral and cell-mediated immune responses in immunized rhesus macaques

scientific article published in March 2003

Efficacy of Human Papillomavirus-16 Vaccine to Prevent Cervical Intraepithelial Neoplasia

scientific article published on 01 January 2006

Estimated susceptibility of Canadian meningococcal B isolates to a meningococcal serogroup B vaccine (MenB-FHbp)

scientific article published on 23 January 2020

Evaluation of a Validated Luminex-Based Multiplex Immunoassay for Measuring Immunoglobulin G Antibodies in Serum to Pneumococcal Capsular Polysaccharides

scientific article published in 2018

Evaluation of a multilocus sequence typing system for Staphylococcus epidermidis ⬇️

scientific article published on November 1, 2003

Evaluation of approaches to monitor Staphylococcus aureus virulence factor expression during human disease.

scientific article

From research to licensure and beyond: clinical development of MenB-FHbp, a broadly protective meningococcal B vaccine

scientific article published on 22 June 2018

Group A Streptococcal Carriage and Seroepidemiology in Children up to 10 Years of Age in Australia.

scientific article

Heterogeneous in vivo expression of clumping factor A and capsular polysaccharide by Staphylococcus aureus: implications for vaccine design

scientific article published on 5 February 2009

Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.

scientific article published on 25 September 2010

Human papillomavirus type 6 virus-like particles present overlapping yet distinct conformational epitopes

scientific article published in June 2003

Human papillomavirus vaccines and prevention of cervical cancer

scientific article published on January 2004

Immunogenicity and Safety of 13-Valent Pneumococcal Conjugate Vaccine in Infants and Toddlers ⬇️

scientific article published on August 23, 2010

Immunogenicity and reactogenicity of a novel vaccine for human papillomavirus 16: a 2-year randomized controlled clinical trial

scientific article published on 01 May 2005

Immunogenicity and safety of 13-valent pneumococcal conjugate vaccine (PCV13) formulated with 2-phenoxyethanol in multidose vials given with routine vaccination in healthy infants: An open-label randomized controlled trial

scientific article published on 4 May 2017

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine compared to a 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naive adults ⬇️

scientific article published on May 18, 2013

Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine in HIV-infected individuals naive to pneumococcal vaccination

scientific article published in July 2015

Immunogenicity, Safety, and Tolerability of Bivalent rLP2086 Meningococcal Group B Vaccine Administered Concomitantly With Diphtheria, Tetanus, and Acellular Pertussis and Inactivated Poliomyelitis Vaccines to Healthy Adolescents

scientific article published on 23 January 2016

Immunogenicity, Tolerability and Safety in Adolescents of Bivalent rLP2086, a Meningococcal Serogroup B Vaccine, Coadministered with Quadrivalent Human Papilloma Virus Vaccine

scientific article published on February 2016

Immunogenicity, safety, and tolerability of the meningococcal serogroup B bivalent rLP2086 vaccine in adult laboratory workers

scientific article published on 18 December 2015

Immunologic responses following administration of a vaccine targeting human papillomavirus Types 6, 11, 16, and 18

scientific article published on 15 May 2006

Importance of specimen type in detecting human papillomavirus DNA from the female genital tract

scientific article published in September 2009

Infectious virions produced from a human papillomavirus type 18/16 genomic DNA chimera

scientific article published on May 2002

Influence of initial vaccination with 13-valent pneumococcal conjugate vaccine or 23-valent pneumococcal polysaccharide vaccine on anti-pneumococcal responses following subsequent pneumococcal vaccination in adults 50 years and older ⬇️

scientific article published on May 18, 2013

Introduction

Isolation, structural characterization, and immunological evaluation of a high-molecular-weight exopolysaccharide from Staphylococcus aureus

scientific article published in April 2003

Kinetics and isotype profile of antibody responses in rhesus macaques induced following vaccination with HPV 6, 11, 16 and 18 L1-virus-like particles formulated with or without Merck aluminum adjuvant

scientific article

Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires

scientific article published on 14 September 2017

Meningococcal Serogroup B Bivalent rLP2086 Vaccine Elicits Broad and Robust Serum Bactericidal Responses in Healthy Adolescents.

scientific article

Meningococcal carriage in adolescents in the United Kingdom to inform timing of an adolescent vaccination strategy

scientific article published on 21 February 2015

Meningococcal serogroup B vaccines: Estimating breadth of coverage

scientific article published on 14 December 2016

Meningococcal serogroup B-specific responses after vaccination with bivalent rLP2086: 4 year follow-up of a randomised, single-blind, placebo-controlled, phase 2 trial.

scientific article

Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States

scientific article published in PLoS ONE

Multilaboratory comparison of Streptococcus pneumoniae opsonophagocytic killing assays and their level of agreement for the determination of functional antibody activity in human reference sera

scientific article

Multiplex Urinary Antigen Detection for 13 Streptococcus pneumoniae Serotypes Improves Diagnosis of Pneumococcal Pneumonia in South African HIV-Infected Adults

scientific article

Neisseria meningitidis Serogroup B Vaccine, Bivalent rLP2086, Induces Broad Serum Bactericidal Activity Against Diverse Invasive Disease Strains Including Outbreak Strains

scientific article published on 11 November 2016

New frontiers in meningococcal vaccines ⬇️

scientific article published on May 1, 2011

Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in mice ⬇️

scientific article published on December 20, 2012

Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus

scientific article published on 17 April 2013

Optimization and validation of a multiplexed luminex assay to quantify antibodies to neutralizing epitopes on human papillomaviruses 6, 11, 16, and 18

scientific article

Optimization of Molecular Approaches to Genogroup Neisseria meningitidis Carriage Isolates and Implications for Monitoring the Impact of New Serogroup B Vaccines

scientific article published on 6 July 2015

Persistence and 4-year boosting of the bactericidal response elicited by two- and three-dose schedules of MenB-FHbp: A phase 3 extension study in adolescents

scientific article published on 12 February 2019

Persistence of Immune Responses Through 36 Months in Healthy Adults After Vaccination With a Novel Staphylococcus aureus 4-Antigen Vaccine (SA4Ag)

scientific article published on 24 December 2019

Phase 1 trial of a 20-valent pneumococcal conjugate vaccine in healthy adults

scientific article published on 05 September 2019

Phase 1/2 Study to Describe the Safety and Immunogenicity of a COVID-19 RNA Vaccine Candidate (BNT162b1) in Adults 18 to 55 Years of Age: Interim Report

preprint

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults

scientific article published on 12 August 2020

Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults.

scientific article published on March 2015

Poor sensitivity of polymerase chain reaction assays of genital skin swabs and urine to detect HPV 6 and 11 DNA in men.

scientific article published on March 2003

Potential impact of the bivalent rLP2086 vaccine onNeisseria meningitidiscarriage and invasive serogroup B disease ⬇️

scientific article published on December 18, 2012

Preclinical evidence for the potential of a bivalent fHBP vaccine to prevent Neisseria meningitidis Serogroup C Disease ⬇️

scientific article published on January 1, 2011

Predicting the Susceptibility of Meningococcal Serogroup B Isolates to Bactericidal Antibodies Elicited by Bivalent rLP2086, a Novel Prophylactic Vaccine

scientific article published on 13 March 2018

Preservative of choice for Prev(e)nar 13™ in a multi-dose formulation ⬇️

scientific article published on June 7, 2011

Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States

scientific article published on 13 May 2011

Prevention of cervical cancer: journey to develop the first human papillomavirus virus-like particle vaccine and the next generation vaccine

scientific article published on 17 March 2016

Priming of human papillomavirus type 11-specific humoral and cellular immune responses in college-aged women with a virus-like particle vaccine

scientific article

Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial

scientific article

Protection of beagle dogs from mucosal challenge with canine oral papillomavirus by immunization with recombinant adenoviruses expressing codon-optimized early genes

article

Quantitative human papillomavirus 16 and 18 levels in incident infections and cervical lesion development

scientific article published on April 2009

RNA-Based COVID-19 Vaccine BNT162b2 Selected for a Pivotal Efficacy Study

scientific article published on 20 August 2020

Real-time monitoring of bacterial infection in vivo: development of bioluminescent staphylococcal foreign-body and deep-thigh-wound mouse infection models

scientific article published on September 2003

Reevaluation of Positivity Cutoff Values for the Pneumococcal Urinary Antigen Detection Assay

scientific article published on 6 November 2017

Regulation of Staphylococcus aureus MntC expression and its role in response to oxidative stress

scientific article

S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccine

scientific article published on 01 October 2019

SA4Ag, a 4-antigen Staphylococcus aureus vaccine, rapidly induces high levels of bacteria-killing antibodies

scientific article

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine ⬇️

scientific article published on 10 December 2020

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

scientific article published on 14 October 2020

Safety and immunogenicity of 13-valent pneumococcal conjugate vaccine formulations with and without aluminum phosphate and comparison of the formulation of choice with 23-valent pneumococcal polysaccharide vaccine in elderly adults: a randomized ope

scientific article published on 27 February 2014

Safety and immunogenicity of a booster dose of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults: A randomized phase 1 study

scientific article published on 09 August 2016

Safety and immunogenicity of a meningococcal B bivalent rLP2086 vaccine in healthy toddlers aged 18-36 months: a phase 1 randomized-controlled clinical trial

scientific article published on October 2012

Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy, non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded, dose-escalation trial

scientific article published on 03 September 2020

Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents

scientific article

Safety, Tolerability, and Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine (PCV20) in Adults 60 to 64 Years of Age

scientific article published on 27 July 2020

Safety, immunogenicity, and tolerability of meningococcal serogroup B bivalent recombinant lipoprotein 2086 vaccine in healthy adolescents: a randomised, single-blind, placebo-controlled, phase 2 trial ⬇️

scientific article published on May 7, 2012

Safety, tolerability, and immunogenicity of a 4-antigen Staphylococcus aureus vaccine (SA4Ag): Results from a first-in-human randomised, placebo-controlled phase 1/2 study

scientific article published in December 2016

Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy Japanese adults

scientific article published on 17 August 2018

Safety, tolerability, and immunogenicity of a single dose 4-antigen or 3-antigen Staphylococcus aureus vaccine in healthy older adults: Results of a randomised trial

scientific article published on 17 November 2016

Safety, tolerability, and immunologic noninferiority of a 13-valent pneumococcal conjugate vaccine compared to a 7-valent pneumococcal conjugate vaccine given with routine pediatric vaccinations in Germany

scientific article published on 22 April 2010

Selection of diverse strains to assess broad coverage of the bivalent FHbp meningococcal B vaccine

scientific article published on 29 January 2020

Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis

scientific article

Sequential administration of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naïve adults 60-64 years of age.

scientific article published on 05 March 2014

Seroprevalence and genital DNA prevalence of HPV types 6, 11, 16 and 18 in a cohort of young Norwegian women: study design and cohort characteristics

article

Simultaneous quantitation of antibodies to neutralizing epitopes on virus-like particles for human papillomavirus types 6, 11, 16, and 18 by a multiplexed luminex assay

scientific article

Staphylococcus aureus Clumping Factor A Remains a Viable Vaccine Target for Prevention of S. aureus Infection

scientific article published on 8 March 2016

Staphylococcus aureus Manganese Transport Protein C Is a Highly Conserved Cell Surface Protein That Elicits Protective Immunity Against S. aureus and Staphylococcus epidermidis ⬇️

scientific article published on April 2, 2012

Staphylococcus aureus: the current state of disease, pathophysiology and strategies for prevention

scientific article published on 27 April 2016

The 13-valent pneumococcal conjugate vaccine (PCV13) elicits cross-functional opsonophagocytic killing responses in humans to Streptococcus pneumoniae serotypes 6C and 7A.

scientific article

The Dual Role of Lipids of the Lipoproteins in Trumenba, a Self-Adjuvanting Vaccine Against Meningococcal Meningitis B Disease.

scientific article published on 7 September 2016

The discovery and development of a novel vaccine to protect against Neisseria meningitidis Serogroup B Disease

scientific article published in November 2014

The path to developing a cervical cancer vaccine ⬇️

scientific article published on October 1, 2010

The role of vaccines in fighting antimicrobial resistance (AMR)

scientific article published on 09 July 2018

The role of vaccines in preventing bacterial antimicrobial resistance

scientific article

Three-dimensional structure and biophysical characterization of Staphylococcus aureus cell surface antigen-manganese transporter MntC

scientific article

Toward vaccines against cervical cancer.

scientific article

Turning the corner on therapeutic cancer vaccines

scientific article published on 08 February 2019

Two Vaccines for Induce a B-Cell-Mediated Immune Response

scientific article published on 22 August 2018

Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia

scientific article published on 8 December 2011

Vaccination against Nosocomial Infections in Elderly Adults

scientific article published on 09 April 2020

Vaccination strategies for the prevention of meningococcal disease.

scientific article

Vaccine Technology III: An ECI Conference held in Puerto Vallarta, Mexico from June 6–11, 2010

scientific article published on 07 July 2011

Vaccine innovations for emerging infectious diseases-a symposium report

scientific article published on 28 October 2019

Vaccine review: “Staphyloccocus aureus vaccines: Problems and prospects” ⬇️

scientific article published on April 23, 2013

Vaccines against cervical cancer

scientific article published in November 2004

Validation of an Immunodiagnostic Assay for Detection of 13 Streptococcus pneumoniae Serotype-Specific Polysaccharides in Human Urine ⬇️

scientific article published on June 6, 2012

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