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List of works by Takashi Nakahara

<em>In vitro</em> analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism

scientific article published on 12 November 2020

A case of advanced HCC treated with lenvatinib after hepatic arterial infusion chemotherapy combined with radiation therapy treatment for portal vein tumor thrombosis in the main trunk

scientific article published on 23 January 2020

A case of liver nocardiosis associated with Crohn's disease while treating infliximab

scientific article published on April 1, 2011

A case with life-threatening secondary sclerosing cholangitis caused by nivolumab

scientific article published on 16 November 2020

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

scientific article published on 16 October 2013

Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection - Pilot study

scientific article published on 16 November 2020

Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C

scientific article published on 13 August 2018

Analysis of Post-Progression Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib

scientific article published on 03 September 2020

Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection

scientific article

CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients

article

Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib

scientific article published on 20 May 2020

Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

scientific article published in December 2013

Clinical outcomes of sorafenib treatment failure for advanced hepatocellular carcinoma and candidates for regorafenib treatment in real-world practice

scientific article published on 27 May 2018

Clinical outcomes of stereotactic body radiotherapy for elderly patients with hepatocellular carcinoma

scientific article published on 24 June 2017

Common Drug Pipelines for the Treatment of Diabetic Nephropathy and Hepatopathy: Can We Kill Two Birds with One Stone?

scientific article published on 13 July 2020

Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis

scientific article published on 9 February 2018

Comparison of clinical outcome of hepatic arterial infusion chemotherapy and sorafenib for advanced hepatocellular carcinoma according to macrovascular invasion and transcatheter arterial chemoembolization refractory status

scientific article published on 10 May 2018

Comparison of hepatic arterial infusion chemotherapy between 5-fluorouracil-based continuous infusion chemotherapy and low-dose cisplatin monotherapy for advanced hepatocellular carcinoma

scientific article published on 23 August 2018

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice

scientific article published on 21 February 2019

Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability

scientific article published on 04 February 2020

Correction to: The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study

scientific article published on 01 November 2018

Correction: Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

scientific article published on 01 January 2019

Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib

scientific article published on 26 June 2019

Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

scientific article published on 11 January 2013

Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study.

scientific article

Differences in characteristics of glucose intolerance between patients with NAFLD and chronic hepatitis C as determined by CGMS

scientific article published on 31 August 2017

Discordant pathological diagnosis of non-alcoholic fatty liver disease: A prospective multicenter study

scientific article published on 17 December 2019

Early changes in ammonia levels and liver function in patients with advanced hepatocellular carcinoma treated by lenvatinib therapy

scientific article published on 20 August 2019

Early experience of seven hepatocellular carcinoma cases treated with regorafenib

scientific article published on 11 October 2018

Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones

scientific article published on 26 October 2015

Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C.

scientific article published on 25 February 2016

Efficacy and safety of daclatasvir plus asunaprevir therapy for chronic hepatitis C patients with renal dysfunction.

scientific article

Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis

scientific article published on 24 March 2017

Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study

scientific article published on 16 August 2017

Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis

scientific article

Efficacy of Lusutrombopag for Thrombocytopenia in Patients with Chronic Liver Disease Scheduled to Undergo Invasive Procedures

scientific article published on 21 October 2020

Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice

scientific article published on 14 June 2019

Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study

scientific article published on 14 May 2012

Emergence of drug resistance-associated variants and changes in serum lipid profiles in sofosbuvir plus ledipasvir-treated chronic hepatitis C patients.

scientific article published on 28 June 2017

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes

scientific article published on 18 September 2018

Erratum to: Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy

scientific article published in January 2018

Evaluation of glycemic variability in chronic liver disease patients with type 2 diabetes mellitus using continuous glucose monitoring

scientific article

Evaluation of the mRECIST and α-fetoprotein ratio for stratification of the prognosis of advanced-hepatocellular-carcinoma patients treated with sorafenib

scientific article published on 11 August 2012

Extracellular water to total body water ratio obtained by bioelectrical impedance analysis determines the dose intensity of lenvatinib for the treatment of patients with advanced hepatocellular carcinoma

scientific article published on 16 December 2020

HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease

scientific article published on 03 February 2019

Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial.

scientific article published on 4 June 2018

Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification

scientific article published on 01 December 2012

ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.

scientific article published on 7 November 2016

Impact of Hepatitis C Virus Eradication on the Clinical Outcome of Patients with Hepatitis C Virus-Related Advanced Hepatocellular Carcinoma Treated with Sorafenib

scientific article published on March 2017

Impact of viral eradication by DAAs on the risk of HCC development, prognosis and portal hypertension in HCV-related compensated cirrhosis patients

scientific article published on 06 August 2020

Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report.

scientific article

Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab

scientific article published on 23 February 2020

Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C.

scientific article published on 6 May 2014

Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

scientific article

Isolated cardiac metastases of hepatocellular carcinoma after resection: a case report

scientific article published on 28 November 2019

Late-onset ornithine transcarbamylase deficiency associated with hyperammonemia

scientific article published on 09 June 2017

Letter of response to the editor

scientific article published on 14 October 2020

Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis

Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C inf

scientific article published on 25 September 2020

Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis

scientific article published on 04 September 2019

Metabolomic-/Lipidomic-based Analysis of Plasma to Diagnose Hepatocellular Ballooning in Patients with Nonalcoholic Fatty Liver Disease: A Multicenter Study

scientific article published on 26 May 2020

Modeling-based response-guided therapy for chronic hepatitis C under glecaprevir/pibrentasvir may identify patients for ultra-short treatment duration

scientific article published on 04 May 2020

Non-invasive liver fibrosis score calculated by combination of virtual touch tissue quantification and serum liver functional tests in chronic hepatitis C patients

scientific article

Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt

scientific article published on 31 January 2019

Pilot study of stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma

article by Yohji Honda et al published 1 January 2014 in Hepato-Gastroenterology

Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C.

scientific article published on 21 December 2013

Preoperative PET-CT is useful for predicting recurrent extrahepatic metastasis of hepatocellular carcinoma after resection

scientific article published on 11 January 2020

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis

scientific article published on 24 October 2019

Rapid and persistent decline in soluble CD163 with successful direct-acting antiviral therapy and associations with chronic hepatitis C histology

scientific article published on 10 July 2018

Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures

scientific article published on 17 October 2018

Real-world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus-related decompensated cirrhosis

scientific article published on 11 September 2020

Recent trend of clinical features in patients with hepatocellular carcinoma

scientific article published on 13 December 2011

Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

scientific article published on 01 January 2018

Ribavirin induces hepatitis C virus genome mutations in chronic hepatitis patients who failed to respond to prior daclatasvir plus asunaprevir therapy

scientific article published on 16 October 2019

Risk factors for exacerbation of gastroesophageal varices and portosystemic encephalopathy during treatment with nucleos(t)ide analogs for hepatitis B virus-related cirrhosis

scientific article published on 8 November 2017

Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases

scientific article published on 02 January 2020

Risk factors for the exacerbation of esophageal varices or portosystemic encephalopathy after sustained virological response with IFN therapy for HCV-related compensated cirrhosis

scientific article published on 05 October 2012

Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.

scientific article

Serum asymmetric dimethylarginine levels are independently associated with procollagen III N-terminal peptide in nonalcoholic fatty liver disease patients

scientific article published on 23 November 2012

Signal activation of hepatitis B virus-related hepatocarcinogenesis by upregulation of SUV39h1

scientific article published on 09 June 2020

Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients

scientific article published on 08 November 2019

Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma

scientific article published in March 2013

Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy

scientific article published on 28 August 2019

The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients

scientific article

The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma; comparison with interferon-based therapy

scientific article published on 19 November 2018

The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study

scientific article published on 09 May 2018

The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients

scientific article published on 15 July 2016

The risks of hepatocellular carcinoma development after HCV eradication are similar between patients treated with peg-interferon plus ribavirin and direct-acting antiviral therapy.

scientific article published on 10 August 2017

Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection

scientific article published on 06 December 2019

Trends in Hepatic Functional Reserve of Patients with Hepatocellular Carcinoma Treated with Tyrosine Kinase Inhibitors

scientific article published on 24 July 2020

Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

scientific article published on 01 May 2020

Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients

scientific article

Usefulness of combining gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for diagnosing the macroscopic classification of small hepatocellular carcinoma

scientific article published on 3 June 2015

Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

scientific article published on 02 April 2013

Wisteria floribunda agglutinin positive Mac-2-binding protein level increases in patients with acute liver injury

scientific article

[A case of advanced hepatocellular carcinoma with lung, brain and lymph node metastases recurred 8 years after hepatectomy successfully treated by operation, radiation and systemic chemotherapy using S-1/CDDP]

scientific article published on 01 August 2012

[A case of clonorchiasis complicated with the expansion of liver cyst]

scientific article published on 01 March 2013

[Case of autoimmune pancreatitis accompanied by autoimmune hemolytic anemia].

scientific article published in May 2009

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