List of works - Joshy Jacob

A synthetic stroma-free germinal center niche for efficient generation of humoral immunity ex vivo.

scientific article published on 21 February 2018

A transgenic mouse model genetically tags all activated CD8 T cells

scientific article published in September 2003

Adjuvanted influenza vaccine administered intradermally elicits robust long-term immune responses that confer protection from lethal challenge

scientific article

An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses ⬇️

scientific article

CD28-B7 interaction modulates short- and long-lived plasma cell function.

scientific article published on 20 August 2012

Clustered Mutations at the Murine and Human IgH Locus Exhibit Significant Linkage Consistent with Templated Mutagenesis

scientific article published on 02 August 2019

Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.

scientific article published on 16 August 2016

DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion

scientific article published in April 2006

DNA vaccines against influenza viruses

scientific article published on January 2009

Differential microenvironment localization of effector and memory CD8 T cells

scientific article published in January 2008

Germinal-center-derived B-cell memory

scientific article published on January 2007

Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

scientific article

Identification of memory B cells using a novel transgenic mouse model

scientific article published in April 2006

Immune complex-mediated enhancement of secondary antibody responses

scientific article published on 3 May 2010

Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent

scientific article

Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus.

scientific article

Incorporation of glycosylphosphatidylinositol-anchored granulocyte- macrophage colony-stimulating factor or CD40 ligand enhances immunogenicity of chimeric simian immunodeficiency virus-like particles

scientific article published on 15 November 2006

Inducible nitric oxide synthase is crucial for plasma cell survival

scientific article published on March 2014

Influenza virus-specific neutralizing IgM antibodies persist for a lifetime

scientific article

Interleukin-10 plays an early role in generating virus-specific T cell anergy

scientific article

Introduction: the complexities of T-cell heterogeneity

scientific article

Local response to microneedle-based influenza immunization in the skin.

scientific article published on 6 March 2012

Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.

scientific article published on 07 June 2016

Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

scientific article published on September 2015

Mining the tree of life: Host defense peptides as antiviral therapeutics

scientific article published on 7 March 2018

Murine Gamma-herpesvirus Immortalization of Fetal Liver-Derived B Cells Requires both the Viral Cyclin D Homolog and Latency-Associated Nuclear Antigen ⬇️

scientific article published on September 8, 2011

Non-neutralizing antibodies induced by seasonal influenza vaccine prevent, not exacerbate A(H1N1)pdm09 disease

scientific article

Ontogeny of the secondary antibody response: origins and clonal diversity

scientific article published on January 2009

Original antigenic sin responses to influenza viruses

scientific article

Perfusion fixation preserves enhanced yellow fluorescent protein and other cellular markers in lymphoid tissues

scientific article published on 11 November 2008

Prior infection with influenza virus but not vaccination leaves a long-term immunological imprint that intensifies the protective efficacy of antigenically drifted vaccine strains

scientific article

Programming the magnitude and persistence of antibody responses with innate immunity

scientific article

Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine.

scientific article

Serological memory and long-term protection to novel H1N1 influenza virus after skin vaccination

scientific article

Somatic Diversification of Rearranged Antibody Gene Segments by Intra- and Interchromosomal Templated Mutagenesis

scientific article published on 13 April 2022

Strategies to alleviate original antigenic sin responses to influenza viruses ⬇️

scientific article published on August 6, 2012

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2

scientific article

Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy.

scientific article published on 17 June 2016

The CD28/B7 pathway: a novel regulator of plasma cell function

scientific article

The enigma of memory B cells in malaria ⬇️

scientific article published on December 1, 2012

The hybrid cytomegalovirus enhancer/chicken beta-actin promoter along with woodchuck hepatitis virus posttranscriptional regulatory element enhances the protective efficacy of DNA vaccines

scientific article published in July 2004

Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets

scientific article

Tracking dendritic cells in vivo: insights into DC biology and function

scientific article published on January 2004

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

scientific article published on 06 August 2009

Transcutaneous immunization with inactivated influenza virus induces protective immune responses

scientific article published on 26 May 2006

bcl-xL is critical for dendritic cell survival in vivo.

scientific article published in October 2004

List of works by Joshy Jacob

A synthetic stroma-free germinal center niche for efficient generation of humoral immunity ex vivo.

A transgenic mouse model genetically tags all activated CD8 T cells

Adjuvanted influenza vaccine administered intradermally elicits robust long-term immune responses that confer protection from lethal challenge

An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses ⬇️

CD28-B7 interaction modulates short- and long-lived plasma cell function.

Clustered Mutations at the Murine and Human IgH Locus Exhibit Significant Linkage Consistent with Templated Mutagenesis

Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.

DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion

DNA vaccines against influenza viruses

Differential microenvironment localization of effector and memory CD8 T cells

Germinal-center-derived B-cell memory

Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

Identification of memory B cells using a novel transgenic mouse model

Immune complex-mediated enhancement of secondary antibody responses

Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent

Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus.

Incorporation of glycosylphosphatidylinositol-anchored granulocyte- macrophage colony-stimulating factor or CD40 ligand enhances immunogenicity of chimeric simian immunodeficiency virus-like particles

Inducible nitric oxide synthase is crucial for plasma cell survival

Influenza virus-specific neutralizing IgM antibodies persist for a lifetime

Interleukin-10 plays an early role in generating virus-specific T cell anergy

Introduction: the complexities of T-cell heterogeneity

Local response to microneedle-based influenza immunization in the skin.

Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.

Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

Mining the tree of life: Host defense peptides as antiviral therapeutics

Murine Gamma-herpesvirus Immortalization of Fetal Liver-Derived B Cells Requires both the Viral Cyclin D Homolog and Latency-Associated Nuclear Antigen ⬇️

Non-neutralizing antibodies induced by seasonal influenza vaccine prevent, not exacerbate A(H1N1)pdm09 disease

Ontogeny of the secondary antibody response: origins and clonal diversity

Original antigenic sin responses to influenza viruses

Perfusion fixation preserves enhanced yellow fluorescent protein and other cellular markers in lymphoid tissues

Prior infection with influenza virus but not vaccination leaves a long-term immunological imprint that intensifies the protective efficacy of antigenically drifted vaccine strains

Programming the magnitude and persistence of antibody responses with innate immunity

Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine.

Serological memory and long-term protection to novel H1N1 influenza virus after skin vaccination

Somatic Diversification of Rearranged Antibody Gene Segments by Intra- and Interchromosomal Templated Mutagenesis

Strategies to alleviate original antigenic sin responses to influenza viruses ⬇️

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2

Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy.

The CD28/B7 pathway: a novel regulator of plasma cell function

The enigma of memory B cells in malaria ⬇️

The hybrid cytomegalovirus enhancer/chicken beta-actin promoter along with woodchuck hepatitis virus posttranscriptional regulatory element enhances the protective efficacy of DNA vaccines

Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets

Tracking dendritic cells in vivo: insights into DC biology and function

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

Transcutaneous immunization with inactivated influenza virus induces protective immune responses

bcl-xL is critical for dendritic cell survival in vivo.