List of works - Tracy J Ruckwardt

A proof of concept for structure-based vaccine design targeting RSV in humans

scientific article published on 01 August 2019

An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection

scientific article published in 2023

Bioorthogonal deprotection on the dendritic cell surface for chemical control of antigen cross-presentation.

scientific article published on 17 March 2015

CD8+ TCR transgenic strains expressing public versus private TCR targeting the respiratory syncytial virus K(d)M2(82-90) epitope demonstrate similar functional profiles

scientific article

CXCR4-dependent HIV-1 infection of differentiated epithelial cells

scientific article published on December 2002

Characterization of respiratory syncytial virus M- and M2-specific CD4 T cells in a murine model

scientific article published on 04 March 2009

Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes.

scientific article published on 11 May 2018

Circulating natural killer and gammadelta T cells decrease soon after infection of rhesus macaques with lymphocytic choriomeningitis virus

scientific article published on July 2009

Consequences of immature and senescent immune responses for infection with respiratory syncytial virus

scientific article published on January 2013

Determinants of early life immune responses to RSV infection

scientific article

Development of a potent Zika virus vaccine using self-amplifying messenger RNA

scientific article published on 07 August 2020

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

scientific article published on 01 June 2020

Epitope-Specific Regulatory CD4 T Cells Reduce Virus-Induced Illness while Preserving CD8 T-Cell Effector Function at the Site of Infection ⬇️

scientific article published on August 4, 2010

Epitope-Specific Serological Assays for RSV: Conformation Matters

scientific article published on 23 February 2019

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

scientific article published on 28 July 2020

Furin cleavage of the HIV-1 Tat protein

scientific article

Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

scientific article published on 01 September 2019

In vitro stimulation with a non-peptidic alkylphosphate expands cells expressing Vgamma2-Jgamma1.2/Vdelta2 T-cell receptors

scientific article

Lipid and stress dependence of amphotericin B ion selective channels in sterol-free membranes

scientific article

Memory Inflation Drives Tissue-Resident Memory CD8 T Cell Maintenance in the Lung After Intranasal Vaccination With Murine Cytomegalovirus

article by Kaitlyn M Morabito et al published 2018 in Frontiers in Immunology

Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4(+) cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism.

scientific article

Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice

scientific article published on December 2011

Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103(+) dendritic cell populations following respiratory infection

scientific article published on 5 April 2017

OMIP-061: 20-Color Flow Cytometry Panel for High-Dimensional Characterization of Murine Antigen-Presenting Cells

scientific article published on 19 August 2019

Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent

scientific article published on 11 January 2016

Pulmonary Dendritic Cell Subsets Shape the Respiratory Syncytial Virus-Specific CD8+ T Cell Immunodominance Hierarchy in Neonates

scientific article

Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response

scientific article

Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities

scientific article published on 19 January 2009

Relative dominance of epitope-specific CD8+ T cell responses in an F1 hybrid mouse model of respiratory syncytial virus infection

scientific article

Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope

scientific article

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

scientific article published on 11 June 2020

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

scientific article published on 05 August 2020

Sequence variation within the dominant amino terminus epitope affects antibody binding and neutralization of human immunodeficiency virus type 1 Tat protein

scientific article published on December 2004

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

scientific article published on 23 June 2020

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

scientific article published on 21 July 2020

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes ⬇️

scientific article published on 12 October 2020

T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.

scientific article

T cell immunity to SARS-CoV-2 following natural infection and vaccination

scientific article published on 23 October 2020

Tat-neutralizing antibodies in vaccinated macaques

scientific article

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

scientific article

Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.

scientific article

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

scientific article

Vaccination with tat toxoid attenuates disease in simian/HIV-challenged macaques

scientific article

Viruslike Particles Encapsidating Respiratory Syncytial Virus M and M2 Proteins Induce Robust T Cell Responses.

scientific article published on 3 November 2016

List of works by Tracy J Ruckwardt

A proof of concept for structure-based vaccine design targeting RSV in humans

An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection

Bioorthogonal deprotection on the dendritic cell surface for chemical control of antigen cross-presentation.

CD8+ TCR transgenic strains expressing public versus private TCR targeting the respiratory syncytial virus K(d)M2(82-90) epitope demonstrate similar functional profiles

CXCR4-dependent HIV-1 infection of differentiated epithelial cells

Characterization of respiratory syncytial virus M- and M2-specific CD4 T cells in a murine model

Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes.

Circulating natural killer and gammadelta T cells decrease soon after infection of rhesus macaques with lymphocytic choriomeningitis virus

Consequences of immature and senescent immune responses for infection with respiratory syncytial virus

Determinants of early life immune responses to RSV infection

Development of a potent Zika virus vaccine using self-amplifying messenger RNA

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

Epitope-Specific Regulatory CD4 T Cells Reduce Virus-Induced Illness while Preserving CD8 T-Cell Effector Function at the Site of Infection ⬇️

Epitope-Specific Serological Assays for RSV: Conformation Matters

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

Furin cleavage of the HIV-1 Tat protein

Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

In vitro stimulation with a non-peptidic alkylphosphate expands cells expressing Vgamma2-Jgamma1.2/Vdelta2 T-cell receptors

Lipid and stress dependence of amphotericin B ion selective channels in sterol-free membranes

Memory Inflation Drives Tissue-Resident Memory CD8 T Cell Maintenance in the Lung After Intranasal Vaccination With Murine Cytomegalovirus

Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4(+) cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism.

Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice

Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103(+) dendritic cell populations following respiratory infection

OMIP-061: 20-Color Flow Cytometry Panel for High-Dimensional Characterization of Murine Antigen-Presenting Cells

Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent

Pulmonary Dendritic Cell Subsets Shape the Respiratory Syncytial Virus-Specific CD8+ T Cell Immunodominance Hierarchy in Neonates

Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response

Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities

Relative dominance of epitope-specific CD8+ T cell responses in an F1 hybrid mouse model of respiratory syncytial virus infection

Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

Sequence variation within the dominant amino terminus epitope affects antibody binding and neutralization of human immunodeficiency virus type 1 Tat protein

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes ⬇️

T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.

T cell immunity to SARS-CoV-2 following natural infection and vaccination

Tat-neutralizing antibodies in vaccinated macaques

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

Vaccination with tat toxoid attenuates disease in simian/HIV-challenged macaques

Viruslike Particles Encapsidating Respiratory Syncytial Virus M and M2 Proteins Induce Robust T Cell Responses.