List of works by Beatrice Schuler-Thurner

A GMP-compliant protocol to expand and transfect cancer patient T cells with mRNA encoding a tumor-specific chimeric antigen receptor

scientific article

A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr).

scientific article published on 31 December 2004

A polyclonal anti-vaccine CD4 T cell response detected with HLA-DP4 multimers in a melanoma patient vaccinated with MAGE-3.DP4-peptide-pulsed dendritic cells

scientific article

A single chain immunotoxin, targeting the melanoma-associated chondroitin sulfate proteoglycan, is a potent inducer of apoptosis in cultured human melanoma cells

scientific article

Anti-cytotoxic T-cell lymphocyte antigen-4-induced regression of spinal cord metastases in association with renal failure, atypical pneumonia, vision loss, and hearing loss

scientific article published on 8 October 2012

Arming T Cells with a gp100-Specific TCR and a CSPG4-Specific CAR Using Combined DNA- and RNA-Based Receptor Transfer

scientific article published on 20 May 2019

Circulation and homing of melanoma-reactive T cells to both cutaneous and visceral metastases after vaccination with monocyte-derived dendritic cells

scientific article published on 01 August 2004

Clinical-Scale Production of CAR-T Cells for the Treatment of Melanoma Patients by mRNA Transfection of a CSPG4-Specific CAR under Full GMP Compliance

scientific article published on 16 August 2019

Combined cytotoxic activity of an infectious, but non-replicative herpes simplex virus type 1 and plasmacytoid dendritic cells against tumour cells.

scientific article published on 21 July 2015

Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells

scientific article published in September 2017

Comparison of two apheresis systems for the collection of CD14+ cells intended to be used in dendritic cell culture

scientific article published on 01 September 2003

Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango.

scientific article

Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg.

scientific article published on 19 August 2013

Differences in phenotype and function between spontaneously occurring melan-A-, tyrosinase- and influenza matrix peptide-specific CTL in HLA-A*0201 melanoma patients

scientific article published on 01 June 2005

Digital karyotyping reveals frequent inactivation of the dystrophin/DMD gene in malignant melanoma

scientific article

Effective clinical-scale production of dendritic cell vaccines by monocyte elutriation directly in medium, subsequent culture in bags and final antigen loading using peptides or RNA transfection

scientific article published in September 2007

Effectiveness and tolerability of ipilimumab: experiences from 198 patients included in a named-patient program in various daily-practice settings and multiple institutions.

scientific article published in September 2014

Efficient elutriation of monocytes within a closed system (Elutra) for clinical-scale generation of dendritic cells

scientific article

Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

scientific article published on 21 December 2010

Functional analysis of tumor-specific Th cell responses detected in melanoma patients after dendritic cell-based immunotherapy

scientific article published on January 2004

Functions of Anti-MAGE T-Cells Induced in Melanoma Patients under Different Vaccination Modalities

scientific article published on 01 May 2008

Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA

Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders

scientific article published on 26 October 2017

Hypertonicity primes malignant melanoma cells for apoptosis.

scientific article published on 13 February 2018

Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors.

scientific article published on 30 April 2018

Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak(®) on CD25(+) cells

scientific article

Immunotherapy of Uveal Melanoma: Vaccination Against Cancer

scientific article published on 01 January 2017

Large-scale generation of mature monocyte-derived dendritic cells for clinical application in cell factories

scientific article published on 01 October 2002

MAGE-A3 is a frequent tumor antigen of metastasized melanoma

scientific article published on 27 November 2004

Ocular diseases in metastatic cutaneous melanoma: review of 108 consecutive patients in two German tertiary centers

scientific article published on 22 January 2014

Polyclonal CTL Responses Observed in Melanoma Patients Vaccinated with Dendritic Cells Pulsed with a MAGE-3.A1 Peptide ⬇️

scientific article published on November 1, 2003

Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination.

scientific article

Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

scientific article published on 7 October 2002

RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis

scientific article

Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.

scientific article

Sarcoidosis Under Dendritic Cell Vaccination Immunotherapy in Long-term Responding Patients with Metastatic Melanoma

scientific article published in June 2017

Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone.

scientific article published on 29 October 2015

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein

scientific article published on 27 June 2017

Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation

scientific article published on 21 June 2010

The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma

scientific article published on 11 August 2018

The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network

scientific article

The siRNA-mediated downregulation of PD-1 alone or simultaneously with CTLA-4 shows enhanced in-vitro CAR-T cell functionality for further clinical development towards the potential use in immunotherapy of melanoma.

scientific article published on 28 April 2018

The use of dendritic cells in cancer immunotherapy

scientific article

Towards a standardized protocol for the generation of monocyte-derived dendritic cell vaccines

scientific article published on 01 January 2010

Tumor-reactive CD4+ T cell responses to the melanoma-associated chondroitin sulphate proteoglycan in melanoma patients and healthy individuals in the absence of autoimmunity

scientific article published on 01 June 2007

Twelve-year survival and immune correlates in dendritic cell-vaccinated melanoma patients.

scientific article

[Vaccination therapy of melanoma]

scientific article published on 01 August 2005

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