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List of works by Erik Serrao

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain

scientific article

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

scientific article published on 8 February 2016

A supramolecular assembly mediates lentiviral DNA integration ⬇️

scientific article published on January 2017

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

scientific article

Alteration of select gene expression patterns in individuals infected with HIV-1.

scientific article published on 30 January 2014

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites

scientific article

Biochemical characterization of novel retroviral integrase proteins

scientific article (publication date: 2013)

Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo

scientific article published on 15 June 2016

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

scientific article published on 10 October 2016

Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75.

scientific article published on 19 April 2014

Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction

scientific article published on 2 August 2013

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

scientific article published on 26 August 2020

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

scientific article published on December 2016

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

scientific article published on 29 June 2016

Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction

scientific article published on 18 March 2013

HIV-1 integrase inhibitors: 2007-2008 update

scientific article

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

scientific article published on 17 May 2017

HemoTypeSC Demonstrates >99% Field Accuracy in a Sickle Cell Disease Screening Initiative in Children of Southeastern Uganda

scientific article published on 26 March 2019

Host and viral determinants for MxB restriction of HIV-1 infection

scientific article

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding.

scientific article published on 11 February 2014

Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

scientific article

Key determinants of target DNA recognition by retroviral intasomes

scientific article published on 30 April 2015

Molecular mechanisms of retroviral integration site selection

scientific article

Multicenter Evaluation of HemoTypeSC as a Point-of-Care Sickle Cell Disease Rapid Diagnostic Test for Newborns and Adults Across India

scientific article published on 01 January 2020

Point-of-Care Screening for Sickle-Cell Disease in Low-Resource Settings: a Multi-Center Evaluation of HemoTypeSC, a Novel Rapid Test

scientific article published on 31 October 2018

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

scientific article published on 05 March 2009

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

scientific article published on 8 April 2009

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.

scientific article published on 13 April 2016

Sites of retroviral DNA integration: From basic research to clinical applications

scientific article published on 28 October 2015

Structural basis for retroviral integration into nucleosomes.

scientific article

Structural basis for spumavirus GAG tethering to chromatin ⬇️

scientific article

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes

scientific article published on 18 March 2016

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency

scientific article published on 24 February 2016

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