List of works - Hiroshi Yasui

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

scientific article

Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo

scientific article

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth

scientific article published on 14 December 2006

FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance

scientific article published in August 2005

Fatty acid synthase is a novel therapeutic target in multiple myeloma

scientific article published on 10 April 2008

Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

scientific article

Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series

scientific article published on 11 July 2019

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

scientific article published on September 2007

MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo

scientific article published on 01 October 2006

Model of translational cancer research in multiple myeloma ⬇️

scientific article published on August 17, 2012

Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.

scientific article published on April 2005

Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application.

scientific article

Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma

scientific article

PI3K/p110{delta} is a novel therapeutic target in multiple myeloma

scientific article

Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells

scientific article published on 17 January 2006

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma

scientific article published on 23 July 2019

Recent advances in the treatment of Multiple Myeloma

scientific article published on 01 October 2006

Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7

scientific article published on 29 July 2019

The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

scientific article

Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment

scientific article

List of works by Hiroshi Yasui

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth

FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance

Fatty acid synthase is a novel therapeutic target in multiple myeloma

Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo

Model of translational cancer research in multiple myeloma ⬇️

Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.

Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application.

Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma

PI3K/p110{delta} is a novel therapeutic target in multiple myeloma

Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma

Recent advances in the treatment of Multiple Myeloma

Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7

The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment