List of works by Matthias Lauth

Antipsychotic drugs regulate hedgehog signaling by modulation of 7-dehydrocholesterol reductase levels

scientific article published on 17 June 2010

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

scientific article

Chronic pancreatitis and systemic inflammatory response syndrome prevent impact of chemotherapy with gemcitabine in a genetically engineered mouse model of pancreatic cancer

scientific article

Corrigendum: identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

scientific article published on 26 October 2015

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

scientific article published on 26 November 2016

DYRK1B regulates Hedgehog-induced microtubule acetylation

article

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.

scientific article published on 30 May 2010

Developmental upregulation of an alternative form of pcp2 with reduced GDI activity.

scientific article published on April 2014

Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas

scientific article

Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.

scientific article published on 21 November 2017

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

scientific article

Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway

Genetic and pharmacologic abrogation of Snail1 inhibits acinar-to-ductal metaplasia in precursor lesions of pancreatic ductal adenocarcinoma and pancreatic injury

scientific article published on 25 January 2018

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

scientific journal article

Genetic targeting of cerebellar Purkinje cells: history, current status and novel strategies

scientific article

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.

scientific article

Hedgehog inhibition with cyclopamine represses tumor growth and prolongs survival in a transgenic mouse model of islet cell tumors.

scientific article published in March 2011

Hedgehog inhibition with the orally bioavailable Smo antagonist LDE225 represses tumor growth and prolongs survival in a transgenic mouse model of islet cell neoplasms

scientific article

Hedgehog signaling and pancreatic tumor development

scientific article published on January 2011

Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

scientific article

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

scientific article

Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies

scientific article published on 24 April 2019

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

scholarly article

Inhibition of GLI1 gene activation by Patched1

scientific article

Inhibition of heat shock protein 90 with AUY922 represses tumor growth in a transgenic mouse model of islet cell neoplasms

scientific article published on 3 October 2014

Insert-containing neurotrophins in teleost fish and their relationship to nerve growth factor

scientific article published in October 2003

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

scientific article published on 30 July 2007

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

scientific article published on 31 March 2008

Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors

scientific article published in February 2017

RAS and Hedgehog--partners in crime

scientific article published on June 2011

RIO kinase 3 acts as a SUFU-dependent positive regulator of Hedgehog signaling

scientific article published on 7 September 2013

Simvastatin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer.

scientific article published on 20 August 2013

Sonic the Hedgehog: A game about aging? Emerging evidence for anti-geriatric effects of Hedgehog signaling (retrospective on DOI 10.1002/bies.201200049).

scientific article published on 29 September 2014

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

scientific article

Stromal biology and therapy in pancreatic cancer: ready for clinical translation?

scientific article published on 03 September 2018

The Hedgehog pathway as a drug target in cancer therapy.

scientific article published on June 2007

The Immune Microenvironment in Pancreatic Cancer

scientific article published on 03 October 2020

The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways

scientific article

The role of pancreatic and duodenal homeobox 1 as a therapeutic target in pancreatic cancer

scientific article

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

scientific article published in Nature Communications

Think inside the BOCs: a mechanism underlying medulloblastoma progression

scientific article published in October 2014

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