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List of works by Stephen T C Wong

3-D CENTERLINE EXTRACTION OF AXONS IN MICROSCOPIC STACKS FOR THE STUDY OF MOTOR NEURON BEHAVIOR IN DEVELOPING MUSCLES

3D Axon structure extraction and analysis in confocal fluorescence microscopy images

scientific article published in August 2008

3D cell nuclei segmentation based on gradient flow tracking

scientific article

76-space analysis of grey matter diffusivity: methods and applications

scientific article

76-space analysis of grey matter diffusivity: methods and applications

scientific article published on 01 January 2005

A 3D multiscale model of cancer stem cell in tumor development

scientific article

A Behavior-Modification, Clinical-Grade Mobile Application to Improve Breast Cancer Survivors' Accountability and Health Outcomes

scientific article published on 01 December 2018

A Deep Learning-Based Decision Support Tool for Precision Risk Assessment of Breast Cancer

scientific article published on 01 May 2019

A High-content screen identifies compounds promoting the neuronal differentiation and the midbrain dopamine neuron specification of human neural progenitor cells

scientific article published on 6 November 2015

A NOVEL SURFACE-BASED GEOMETRIC APPROACH FOR 3D DENDRITIC SPINE DETECTION FROM MULTI-PHOTON EXCITATION MICROSCOPY IMAGES.

scientific article published on June 2009

A Novel Method of Transcriptional Response Analysis to Facilitate Drug Repositioning for Cancer Therapy ⬇️

scientific article published on November 22, 2011

A Time-Series Method for Automated Measurement of Changes in Mitotic and Interphase Duration from Time-Lapse Movies ⬇️

scientific article published on September 26, 2011

A computational framework for studying neuron morphology from in vitro high content neuron-based screening

scientific article

A computerized cellular imaging system for high content analysis in Monastrol suppressor screens

scientific article published on 22 June 2005

A global spatial similarity optimization scheme to track large numbers of dendritic spines in time-lapse confocal microscopy

scientific article published in November 2010

A hybrid approach to automatic clustering of white matter fibers

scientific article published on 13 August 2009

A local fast marching-based diffusion tensor image registration algorithm by simultaneously considering spatial deformation and tensor orientation

scientific article published on 9 April 2010

A multifaceted study of hospital variables and interventions to improve inpatient satisfaction in a multi-hospital system

scientific article published on 01 December 2020

A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons

scientific article

A neuroinformatics database system for disease-oriented neuroimaging research

scientific article published on March 2004

A novel cell segmentation method and cell phase identification using Markov model

scientific article

A novel method for cortical sulcal fundi extraction

scientific article published on 01 January 2008

A novel tracing algorithm for high throughput imaging Screening of neuron-based assays.

scientific article published on 20 September 2006

A quantitative analysis of F-actin features and distribution in fluorescence microscopy images to distinguish cells with different modes of motility

scientific article published on January 2013

A quantitative analytic pipeline for evaluating neuronal activities by high‐throughput synaptic vesicle imaging ⬇️

scientific article published on June 23, 2012

A quantitative study of factors affecting in vivo bioluminescence imaging

scientific article

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

scientific article published on 9 June 2013

A web-based federated neuroinformatics model for surgical planning and clinical research applications in epilepsy

scientific article published on January 2004

Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

scientific article published on 01 January 2021

An Image Based System Biology Approach for Alzheimer's Disease Pathway Analysis

scientific article published on 01 April 2009

An XML message broker framework for exchange and integration of microarray data

scientific article

An automated method for cell detection in zebrafish.

scientific article

An automated pipeline for dendrite spine detection and tracking of 3D optical microscopy neuron images of in vivo mouse models

scientific article published on 12 May 2009

An automatic and robust algorithm of reestablishment of digital dental occlusion

scientific article

An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data ⬇️

scientific article published on July 1, 2011

An image driven systems biology approach for neurodegenerative disease studies in the TSC-mTOR pathway ⬇️

scientific article published on 01 May 2009

An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling

scientific article published on 29 April 2008

Analysis of the Implementation of Telehealth Visits for Care of Patients With Cancer in Houston During the COVID-19 Pandemic

scientific article published on 07 October 2020

Automated Axon Tracking of 3D Confocal Laser Scanning Microscopy Images Using Guided Probabilistic Region Merging

Automated axon tracking of 3D confocal laser scanning microscopy images using guided probabilistic region merging

scientific article

Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field

scientific article published on 14 May 2009

Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays.

scientific article published on 27 January 2007

Automated neurite labeling and analysis in fluorescence microscopy images

scientific article published in June 2006

Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy

scientific article published in April 2006

Automatic dendritic spine analysis in two-photon laser scanning microscopy images

scientific article

Bayesian Peptide Peak Detection for High Resolution TOF Mass Spectrometry ⬇️

scientific article published on November 1, 2010

Bayesian variable selection for gene expression modeling with regulatory motif binding sites in neuroinflammatory events

scientific article published on January 2006

Bioluminescence imaging of heme oxygenase-1 upregulation in the Gua Sha procedure

scientific article

Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein

scientific article published on June 2009

Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies

scientific article

Boosting alternating decision trees modeling of disease trait information

scientific article published on 30 December 2005

Brain tissue segmentation based on DTI data

scientific article

Cancer classification and prediction using logistic regression with Bayesian gene selection

scientific article published in August 2004

Cancer stem cell, niche and EGFR decide tumor development and treatment response: A bio-computational simulation study

scientific article published on 20 October 2010

Cell segmentation using front vector flow guided active contours

scientific article published on 01 January 2009

Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells

scientific article (publication date: 23 May 2016)

Cellular phenotype recognition for high-content RNA interference genome-wide screening

scientific article published on January 2008

Chapter 17: bioimage informatics for systems pharmacology

scientific article

Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging

scientific article

Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1.

scientific article

Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation

scientific article published on March 2013

Clusterin Impairs Hepatic Insulin Sensitivity and Adipocyte Clusterin Associates With Cardiometabolic Risk

scientific article published on 18 January 2019

Combining deep learning and coherent anti-Stokes Raman scattering imaging for automated differential diagnosis of lung cancer

scientific article published in October 2017

Comparison of Bayesian and regression models in missing enzyme identification

scientific article published in January 2008

Comparison of Direct Patient Care Costs and Quality Outcomes of the Teaching and Non-Teaching Hospitalist Services at a Large Academic Medical Center

scientific article published on 13 October 2017

Comparison of reversible-jump Markov-chain-Monte-Carlo learning approach with other methods for missing enzyme identification

scientific article published on 15 September 2007

Computational Systems Bioinformatics and Bioimaging for Pathway Analysis and Drug Screening

scientific article published on August 2008

Computational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancer

scientific article

Computational prediction models for early detection of risk of cardiovascular events using mass spectrometry data

scientific article

Computerized image analysis for quantitative neuronal phenotyping in zebrafish

scientific article published on 20 December 2005

Conditional random pattern algorithm for LOH inference and segmentation

scientific article

Conditional random pattern model for copy number aberration detection

scientific article

Context based mixture model for cell phase identification in automated fluorescence microscopy

Coronary artery segmentation using geometric moments based tracking and snake-driven refinement ⬇️

scientific article published on January 1, 2010

Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion

scientific article published on 8 September 2010

Dendritic spine detection using curvilinear structure detector and LDA classifier

scientific article published on 13 March 2007

Detection of blob objects in microscopic zebrafish images based on gradient vector diffusion

scientific article published on 01 October 2007

Detection of molecular particles in live cells via machine learning

scientific article

Differential Diagnosis of Lung Carcinoma With Coherent Anti-Stokes Raman Scattering Imaging ⬇️

scientific article published on December 1, 2012

Differential diagnosis of lung carcinoma with three-dimensional quantitative molecular vibrational imaging ⬇️

scientific article published on June 1, 2012

Differential effects of low‐ and high‐dose GW2974, a dual epidermal growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion ⬇️

scientific article published on November 1, 2012

Diffusion tensor-based fast marching for modeling human brain connectivity network

scientific article published on 28 October 2010

Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis.

scientific article

Drug effects analysis on cells using a high throughput microfluidic chip

scientific article published on February 1, 2011

DrugComboRanker: drug combination discovery based on target network analysis

scientific article published on June 2014

DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies

scientific article published on 15 May 2013

Dual CARS and SHG image acquisition scheme that combines single central fiber and multimode fiber bundle to collect and differentiate backward and forward generated photons

scientific article published on 16 May 2016

Epithelial derived CTGF promotes breast tumor progression via inducing EMT and collagen I fibers deposition

scientific article

Epithelial-Mesenchymal Plasticity in Organotropism Metastasis and Tumor Immune Escape

scientific article published on 25 May 2019

Executive dysfunction and left frontal white matter hyperintensities are correlated with neuropsychiatric symptoms in stroke patients with confluent white matter hyperintensities

scientific article published on 15 September 2010

Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles ⬇️

scientific article published on January 1, 2010

Genome-wide analysis of DNA copy number alterations and loss of heterozygosity in intracranial germ cell tumors.

scientific article

High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles

scientific article

How cells explore shape space: a quantitative statistical perspective of cellular morphogenesis

scientific article

INTEGRATING MULTI-SCALE BLOB/CURVILINEAR DETECTOR TECHNIQUES AND MULTI-LEVEL SETS FOR AUTOMATED SEGMENTATION OF STEM CELL IMAGES

scientific article published on January 2009

Identification of biomarkers for risk stratification of cardiovascular events using genetic algorithm with recursive local floating search

scientific article

Identification of novel small-molecule inhibitors of glioblastoma cell growth and invasion by high-throughput screening ⬇️

scientific article published on August 1, 2012

Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer

scientific article published on 2 April 2013

Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.

scientific article

Image-Based Chemical Screening Identifies Drug Efflux Inhibitors in Lung Cancer Cells ⬇️

scientific article published on September 14, 2010

Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways

scientific article published on 28 October 2019

Integration of multiscale dendritic spine structure and function data into systems biology models

scientific article

Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis.

scientific article

Joint registration and segmentation of serial lung CT images for image-guided lung cancer diagnosis and therapy

scientific article published on 25 August 2009

Least-square conformal brain mapping with spring energy

scientific article published on December 2007

METEOR: An Enterprise Health Informatics Environment to Support Evidence-Based Medicine

scientific article

MR analysis of regional brain volume in adolescent idiopathic scoliosis: neurological manifestation of a systemic disease.

scientific article published on April 2008

Mammary precancerous stem and non-stem cells evolve into cancers of distinct subtypes

scientific article published on 06 November 2018

Mechanical unloading promotes myocardial energy recovery in human heart failure

scientific article

MicroRNA-integrated and network-embedded gene selection with diffusion distance

scientific article

Molecular dynamics simulation study reveals potential substrate entry path into γ-secretase/presenilin-1.

scientific article published on 2 July 2015

Motion Artifact Correction of Multi-Photon Imaging of Awake Mice Models Using Speed Embedded HMM ⬇️

scientific article published on 01 January 2010

Motion correction for cellular-resolution multi-photon fluorescence microscopy imaging of awake head-restrained mice using speed embedded HMM ⬇️

scientific article published on September 3, 2011

Multi scale and slice-based approach for automatic spine detection

scientific article published on January 1, 2010

Multiclass cancer classification by using fuzzy support vector machine and binary decision tree with gene selection

scientific article

Multimodal non-linear optical imaging for label-free differentiation of lung cancerous lesions from normal and desmoplastic tissues

scientific article

Multiple distinct clones may co-exist in different lineages in myelodysplastic syndromes

scientific article

Multiple nuclei tracking using integer programming for quantitative cancer cell cycle analysis

scientific article

Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation

scientific journal article

Network-based analysis reveals stronger local diffusion-based connectivity and different correlations with oral language skills in brains of children with high functioning autism spectrum disorders

scientific article published on 24 September 2012

Neuroimaging predictors for depressive symptoms in cerebral small vessel disease

scientific article published in October 2010

Neuroimaging predictors of cognitive impairment in confluent white matter lesion: volumetric analyses of 99 brain regions

scientific article published on 28 November 2007

Nonlinear motion compensation using cubature Kalman filter forin vivofluorescence microendoscopy in peripheral lung cancer intervention ⬇️

scientific article published on January 1, 2013

Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy

scientific article published on 7 November 2007

Novel modeling of cancer cell signaling pathways enables systematic drug repositioning for distinct breast cancer metastases

scientific article published on 04 October 2013

OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages

scientific article published on 10 January 2020

ONLINE THREE-DIMENSIONAL DENDRITIC SPINES MOPHOLOGICAL CLASSIFICATION BASED ON SEMI-SUPERVISED LEARNING

scientific article

Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity

scientific article

On-the-spot lung cancer differential diagnosis by label-free, molecular vibrational imaging and knowledge-based classification ⬇️

scientific article published on September 1, 2011

Online 4-D CT Estimation for Patient-Specific Respiratory Motion Based on Real-Time Breathing Signals ⬇️

scientific article published on 01 January 2010

Online Phenotype Discovery based on Minimum Classification Error Model

scientific article published in April 2009

Oriented Markov random field based dendritic spine segmentation for fluorescence microscopy images

scientific article

Parameters selection in gene selection using Gaussian kernel support vector machines by genetic algorithm

scientific article

Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays

scientific article

Peak Tree: A New Tool for Multiscale Hierarchical Representation and Peak Detection of Mass Spectrometry Data ⬇️

scientific article published on July 1, 2011

Predictors for cognitive decline in patients with confluent white matter hyperintensities

scientific article published on 30 May 2012

Predictors for cortical gray matter volume in stroke patients with confluent white matter changes

scientific article published on 04 January 2014

Prevalence of in-hospital nonsteroidal antiinflammatory drug exposure in patients with a primary diagnosis of heart failure

scientific article published on 26 February 2017

Preventing inpatient falls with injuries using integrative machine learning prediction: a cohort study

scientific article published on 12 December 2019

Prognostic Gene Discovery in Glioblastoma Patients using Deep Learning

article

Progress of engineered antibody-targeted molecular imaging for solid tumors (Review)

scientific article published on January 1, 2008

Protein structure similarity from Principle Component Correlation analysis

scientific article

Radiation-activated secretory proteins of <i>Scgb1a1</i> <sup>+</sup> club cells increase the efficacy of immune checkpoint blockade in lung cancer

scientific article published on 20 September 2021

Real-time monitoring of cell viability using direct electrical measurement with a patch-clamp microchip ⬇️

scientific article published on October 1, 2011

Reconstruction of central cortical surface from brain MRI images: method and application

scientific article published on 27 December 2007

Reconstruction of the neuromuscular junction connectome

scientific article

Registration of 3-D CT and 2-D flat images of mouse via affine transformation

scientific article published in September 2008

Repulsive force based snake model to segment and track neuronal axons in 3D microscopy image stacks.

scientific article published on 24 July 2006

Reversible jump MCMC approach for peak identification for stroke SELDI mass spectrometry using mixture model

scientific article

Robust 3D reconstruction and identification of dendritic spines from optical microscopy imaging

scientific article published on 24 July 2008

Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces ⬇️

scientific article published on September 13, 2010

Sepsis outcomes in solid organ transplant recipients

scientific article published on 02 December 2019

Simultaneous consideration of spatial deformation and tensor orientation in diffusion tensor image registration using local fast marching patterns

scientific article published in January 2009

Spatial Transcriptomics Depict Ligand–Receptor Cross-talk Heterogeneity at the Tumor-Stroma Interface in Long-Term Ovarian Cancer Survivors

scientific article published on 14 February 2023

Systems biology-based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma

scientific article published on 01 October 2018

Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer.

scientific article published on 22 March 2018

The Modulatory Role of MicroRNA-873 in the Progression of KRAS-Driven Cancers

scientific article published on 13 December 2018

The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability

scientific article published on 01 November 2018

The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models ⬇️

scientific article published on March 11, 2011

The knowledge-integrated network biomarkers discovery for major adverse cardiac events

scientific article

The miR-223/nuclear factor I-A axis regulates glial precursor proliferation and tumorigenesis in the CNS.

scientific article published on August 2013

The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells

scientific article

Three-dimensional vasculature reconstruction of tumour microenvironment via local clustering and classification

scientific article published on August 2013

Tissue Probability Map Constrained 4-D Clustering Algorithm for Increased Accuracy and Robustness in Serial MR Brain Image Segmentation

scientific article published in January 2011

Towards automated cellular image segmentation for RNAi genome-wide screening

scientific article published on 01 January 2005

Tracking molecular particles in live cells using fuzzy rule-based system

scientific article

Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform

scientific article published on 10 December 2013

Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation

scientific article

Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model

scientific article published on 19 February 2015

Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study

scientific article

Two birds, one stone: hesperetin alleviates chemotherapy-induced diarrhea and potentiates tumor inhibition.

scientific article

Using Genetic and Clinical Factors to Predict Tacrolimus Dose in Renal Transplant Recipients ⬇️

scientific article published on October 1, 2010

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens

scientific article

Using nonlinear diffusion and mean shift to detect and connect cross-sections of axons in 3D optical microscopy images.

scientific article published on 25 March 2008

Vasodilation by in vivo activation of astrocyte endfeet via two-photon calcium uncaging as a strategy to prevent brain ischemia.

scientific article published on December 2013

Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer

scientific article

Workflow and methods of high-content time-lapse analysis for quantifying intracellular calcium signals

scientific article

ZFIQ: a software package for zebrafish biology.

scientific article published on 18 December 2007

Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss

scientific article published on 8 February 2006

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