List of works by Ricardo E Dolmetsch

16p11.2 Deletion Syndrome Mice Display Sensory and Ultrasonic Vocalization Deficits During Social Interactions.

scientific article

16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

scientific article published on 10 November 2020

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

scientific article published on 26 July 2016

A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.

scientific article

Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome

scientific article published on 23 December 2019

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.

scientific article

Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels

scientific article published on June 2015

Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells

scientific article

Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome

scientific article

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

scientific article published on 4 February 2016

CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events.

scientific article

Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

scientific journal article

Calcium channels light up.

scientific article published in July 2007

Calcium imaging of cortical neurons using Fura-2 AM.

scientific article

Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development

scientific article

Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2.

scientific article

Cytoplasmic location of α1A voltage-gated calcium channel C-terminal fragment (Cav2.1-CTF) aggregate is sufficient to cause cell death

scientific article

Direct in vivo assessment of human stem cell graft-host neural circuits

scientific article published on 25 April 2015

Excitation-transcription coupling: signaling by ion channels to the nucleus

scientific article

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis

scientific article

Generating human neurons in vitro and using them to understand neuropsychiatric disease.

scientific article published on 23 June 2014

Identification of Orai1 channel inhibitors by using minimal functional domains to screen small molecule microarrays

scientific article

In vitro human corticogenesis

scientific article

Induction of protein-protein interactions in live cells using light

scientific article

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

scientific article

MicroRNA-mediated conversion of human fibroblasts to neurons.

scientific article

Modeling Timothy syndrome with iPS cells

scientific article

Molecular mechanisms of autism: a possible role for Ca2+ signaling

scientific article published on February 2007

PIKfyve mediates the motility of late endosomes and lysosomes in neuronal dendrites

scientific article published on 29 July 2015

PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death

scientific article

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

scientific article

SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

scientific article

STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels

scientific article published on 21 August 2009

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

scientific article

State-dependent signaling by Cav1.2 regulates hair follicle stem cell function

scientific article published in June 2013

Straight talk with... Ricardo Dolmetsch. Interview by Elie Dolgin

scientific article published in November 2013

The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor

scientific article published on November 2006

The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels ⬇️

scientific article published on October 1, 2010

The carboxy-terminal fragment of alpha(1A) calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells.

scientific article

The human brain in a dish: the promise of iPSC-derived neurons

scientific article published on June 2011

The tumor suppressor eIF3e mediates calcium-dependent internalization of the L-type calcium channel CaV1.2.

scientific article published on August 2007

Time-lapse imaging of a dynamic phosphorylation-dependent protein-protein interaction in mammalian cells

scientific article

Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons

scientific article published on 13 January 2013

Translating genome-wide association findings into new therapeutics for psychiatry

scientific article

TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size

scientific article

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

scientific article

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

scientific article

Using light to control signaling cascades in live neurons ⬇️

scientific article published on September 17, 2010

Paulina is supported by:

About Paulina

Help