List of works - Lorena Zentilin

A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9

scientific article

AAV vector encoding human VEGF165-transduced pectineus muscular flaps increase the formation of new tissue through induction of angiogenesis in an in vivo chamber for tissue engineering: A technique to enhance tissue and vessels in microsurgically e

scientific article published on January 2015

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

scientific article published on January 2004

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

scientific article published on 11 June 2015

Adeno-associated virus vectors as therapeutic and investigational tools in the cardiovascular system

scientific article (publication date: 23 May 2014)

Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs.

scientific article

Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

scientific article published on 01 June 2008

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

scientific article

Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice.

scientific article published on June 2008

Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels.

scientific article published on 3 January 2006

Carbon nanotubes instruct physiological growth and functionally mature syncytia: nongenetic engineering of cardiac myocytes

scientific article

Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes

scientific article published on 28 March 2012

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction.

scientific article published on 17 December 2009

Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction.

scientific article published on 11 August 2014

Functional screening identifies miRNAs inducing cardiac regeneration.

scientific article

Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction

scientific article

Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

scientific article published in 2023

Improved survival of ischemic cutaneous and musculocutaneous flaps after vascular endothelial growth factor gene transfer using adeno-associated virus vectors

scientific article

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression.

scientific article published on 14 May 2009

Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

scientific article published in April 2003

Intracoronary Cytoprotective Gene Therapy: A Study of VEGF-B167 in a Pre-Clinical Animal Model of Dilated Cardiomyopathy

scientific article published in July 2015

Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B in Canine Patients with Dilated Cardiomyopathy: A Short-Term Feasibility Study

article

Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

scientific article published on 29 April 2010

Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

scientific journal article

Microsurgical arterovenous loops and biological templates: a novel in vivo chamber for tissue engineering.

scientific article

Neuronal hemoglobin affects dopaminergic cells' response to stress

scientific article published on 05 January 2017

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

scientific article published on 26 June 2018

Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer ⬇️

scientific article published on November 17, 2011

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models

scientific article published on 05 October 2009

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

scientific article published on 9 April 2012

Sustained Expression of Vascular Endothelial Growth Factor and Angiopoietin-1 Improves Blood–Spinal Cord Barrier Integrity and Functional Recovery after Spinal Cord Injury ⬇️

scientific article published on October 28, 2010

Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins

scientific journal article

Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation.

scientific article

List of works by Lorena Zentilin

A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9

AAV vector encoding human VEGF165-transduced pectineus muscular flaps increase the formation of new tissue through induction of angiogenesis in an in vivo chamber for tissue engineering: A technique to enhance tissue and vessels in microsurgically e

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

Adeno-associated virus vectors as therapeutic and investigational tools in the cardiovascular system

Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs.

Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice.

Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels.

Carbon nanotubes instruct physiological growth and functionally mature syncytia: nongenetic engineering of cardiac myocytes

Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction.

Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction.

Functional screening identifies miRNAs inducing cardiac regeneration.

Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction

Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

Improved survival of ischemic cutaneous and musculocutaneous flaps after vascular endothelial growth factor gene transfer using adeno-associated virus vectors

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression.

Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

Intracoronary Cytoprotective Gene Therapy: A Study of VEGF-B167 in a Pre-Clinical Animal Model of Dilated Cardiomyopathy

Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B in Canine Patients with Dilated Cardiomyopathy: A Short-Term Feasibility Study

Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling

Microsurgical arterovenous loops and biological templates: a novel in vivo chamber for tissue engineering.

Neuronal hemoglobin affects dopaminergic cells' response to stress

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer ⬇️

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

Sustained Expression of Vascular Endothelial Growth Factor and Angiopoietin-1 Improves Blood–Spinal Cord Barrier Integrity and Functional Recovery after Spinal Cord Injury ⬇️

Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins

Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation.