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List of works by Léa Payen

(E)-1,1,4,4-Tetramethyl-2-tetrazene (TMTZ): A Prospective Alternative to Hydrazines in Rocket Propulsion.

scientific article

<i>In Vivo</i> Characterization of the Toxicological Properties of DPhP, One of the Main Degradation Products of Aryl Phosphate Esters

scientific article published on 09 December 2020

A template model for studying anticancer drug efflux transporter inhibitors in vitro

scientific article published on 08 August 2012

ABCG2: recent discovery of potent and highly selective inhibitors

scientific article published on June 2013

Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.

scientific article published on March 2002

Cross-platform comparison for the detection of RAS mutations in cfDNA (ddPCR Biorad detection assay, BEAMing assay, and NGS strategy).

scientific article published on 20 April 2018

Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences

scientific article published on 05 May 2016

Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach.

scientific article

Dexamethasone down-regulates ABCG2 expression levels in breast cancer cells.

scientific article

Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil

scientific article published on 7 October 2010

Embryonated Chicken Tumor Xenografts Derived from Circulating Tumor Cells as a Relevant Model to Study Metastatic Dissemination: A Proof of Concept

scientific article published in 2022

Evaluation of pre-analytical conditions and comparison of the performance of several digital PCR assays for the detection of major EGFR mutations in circulating DNA from non-small cell lung cancers: the CIRCAN_0 study

scientific article published on 21 September 2017

Impact of Interleukin-6 on Drug-Metabolizing Enzymes and Transporters in Intestinal Cells

scientific article published on 20 December 2019

Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes.

scientific article published on 25 March 2013

Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution

scientific article published on April 2016

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

scientific article

MRP8/ABCC11 expression is regulated by dexamethasone in breast cancer cells and is associated to progesterone receptor status in breast tumors

scientific article published on 20 January 2011

Metabolomics and cytotoxicity of monomethylhydrazine (MMH) and (E)-1,1,4,4-tetramethyl-2-tetrazene (TMTZ), two liquid propellants

scientific article published on 07 June 2018

Multidrug resistance ABC transporter structure predictions by homology modeling approaches

scientific article published on March 2011

O6-methylguanine-DNA methyltransferase (MGMT) status in neuroendocrine tumors: a randomized phase II study (MGMT-NET)

scientific article published on 14 February 2019

Pharmacokinetic interactions in mice between irinotecan and MBL-II-141, an ABCG2 inhibitor.

scientific article published on 16 February 2017

Pregnane X receptor-dependent and -independent effects of 2-acetylaminofluorene on cytochrome P450 3A23 expression and liver cell proliferation

scientific article

Profiling of circulating tumor DNA in plasma of non-small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation i

scientific article published on 21 May 2019

Quantification and kinetic study in plasma and tissues of (E)-1,1,4,4-tetramethyl-2-tetrazene, a liquid propellant and a transformation product of 1,1-dimethyl hydrazine

scientific article published on 17 June 2015

Quantification of β-aminopropionitrile, an inhibitor of lysyl oxidase activity, in plasma and tumor of mice by liquid chromatography tandem mass spectrometry

scientific article published on 14 January 2014

Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model.

scientific article published on 6 February 2013

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

scientific article

Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence

scientific article published on 14 August 2019

Simultaneous quantification of 5-FU, 5-FUrd, 5-FdUrd, 5-FdUMP, dUMP and TMP in cultured cell models by LC-MS/MS.

scientific article

Structure-activity relationship study: Mechanism of cyto-genotoxicity of Nitropyrazole-derived high energy density materials family

The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells

scientific article published on May 2016

The oncogenic and druggable hPG80 (Progastrin) is overexpressed in multiple cancers and detected in the blood of patients

scientific article published on 24 December 2019

Toxicokinetics and tolerance of a high energy material 3,4,5-trinitropyrazole (TNP) in mice

scientific article published on 26 June 2018

ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells ⬇️

scientific article published on November 8, 2010

p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose.

scientific article published on 7 February 2013

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