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List of works by Tracy T Batchelor

A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients

scientific article

A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients

scientific article

A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma

scientific article

ACTR-76. FINAL RESULTS FROM A PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article published on 6 November 2017

AT-36PANOBINOSTAT IN COMBINATION WITH BEVACIZUMAB FOR RECURRENT GLIOBLASTOMA AND ANAPLASTIC GLIOMA

AT-37PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article published in November 2014

ATNT-14PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

scientific article

Advances in neuroimaging techniques for the evaluation of tumor growth, vascular permeability, and angiogenesis in gliomas

scientific article

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival

scientific article published on 4 April 2016

Angiogenesis as a therapeutic target in malignant gliomas

scientific article published on June 2009

Angiogenesis in brain tumours

scientific article published on August 2007

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy

scientific article

Anti-vascular endothelial growth factor therapy for malignant glioma

scientific article published on May 2009

Antiangiogenic agents for the treatment of glioblastoma

scientific article published on December 2007

Antiangiogenic therapy for glioblastoma: current status and future prospects

scientific article

BM-07GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS

Bayesian Adaptive Randomized Trial Design for Patients With Recurrent Glioblastoma ⬇️

scientific article published on May 29, 2012

Biomarkers of response and resistance to antiangiogenic therapy

scientific article

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

scientific article published on 04 February 2019

Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.

scientific article published on 4 April 2016

Early changes in glioblastoma metabolism measured by MR spectroscopic imaging during combination of anti-angiogenic cediranib and chemoradiation therapy are associated with survival.

scientific article published on 12 June 2017

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice

scientific article

Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma

scientific article published on 08 June 2020

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

scientific article published on 26 September 2015

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

scientific article published on 23 March 2020

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas

scientific article published on 9 November 2016

Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape

scientific article

Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.

scientific article

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma

scientific article published on 04 July 2013

Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion.

scientific article published on 29 November 2011

Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib

scientific article

L265P mutation and loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas

scientific article published on 01 February 2019

Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma.

scientific article published on 23 February 2015

Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation

scientific article

Mechanisms and therapeutic implications of hypermutation in gliomas

scientific article published on 15 April 2020

NIMG-68. MRI CHANGES IN NEWLY DIAGNOSED GLIOBLASTOMA PATIENTS TREATED AS PART OF A PHASE II TRIAL WITH BAVITUXIMAB, RADIATION, AND TEMOZOLOMIDE

New Directions in Anti-Angiogenic Therapy for Glioblastoma

scientific article published on 12 January 2017

ONGOING CLINICAL TRIALS

article

PHASE II TRIAL OF THE PHOSPHATIDYINOSITOL-3 KINASE (PI3K) INHIBITOR BUPARLISIB (BKM120) IN RECURRENT GLIOBLASTOMA CONDUCTED BY THE IVY FOUNDATION EARLY PHASE CLINICAL TRIALS CONSORTIUM.

scientific article published in July 2014

Pathway inhibition: emerging molecular targets for treating glioblastoma

scientific article

Phase 2 study of dose-intense temozolomide in recurrent glioblastoma

scientific article

Phase I and biomarker study of plerixafor and bevacizumab in recurrent high-grade glioma.

scientific article

Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma ⬇️

scientific article published on October 8, 2011

Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide ⬇️

scientific article published on September 7, 2010

Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma

scientific article

Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma

scientific article

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma

scientific article

Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma.

scientific article published on 16 November 2016

Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma

scientific article

Primary central nervous system lymphoma

scientific article published on 05 October 2018

Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI

scientific article published in Scientific Reports

Publisher Correction: Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

scientific article published on 18 June 2020

Reply to B. Freidlin et al.

scientific article published in March 2013

Response criteria for glioma

scientific article

Serial Magnetic Resonance Spectroscopy Reveals a Direct Metabolic Effect of Cediranib in Glioblastoma ⬇️

scientific article published on April 20, 2011

Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

scientific article published on 01 June 2020

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

scientific article published on 07 January 2019

Super-Resolution Whole-Brain 3D MR Spectroscopic Imaging for Mapping D-2-Hydroxyglutarate and Tumor Metabolism in Isocitrate Dehydrogenase 1-mutated Human Gliomas

scientific article published on 07 January 2020

T(1)- and T(2)(*)-dominant extravasation correction in DSC-MRI: part II-predicting patient outcome after a single dose of cediranib in recurrent glioblastoma patients

scientific article published on 20 April 2011

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

scientific article

VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects

scientific article published on 25 April 2007

Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy

scientific article published on 18 August 2013

Vessel caliber--a potential MRI biomarker of tumour response in clinical trials.

scientific article

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

scientific article published on 20 December 2016

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