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List of works by Michal Lotem

A melanoma multiepitope polypeptide induces specific CD8+ T-cell response

scientific article published on November 2007

A new role of vemurafenib as a neoadjuvant treatment of axillary and brain melanoma metastases

scientific article published on 23 December 2013

Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade.

scientific article published on 18 May 2016

Adoptive cell therapy: past, present and future.

scientific article published on January 2017

Autologous melanoma vaccine induces antitumor and self-reactive immune responses that affect patient survival and depend on MHC class II expression on vaccine cells

scientific article

CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity.

scientific article published on March 2002

Capture of tumor cell membranes by trogocytosis facilitates detection and isolation of tumor-specific functional CTLs

scientific article

Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma ⬇️

scientific article published on October 1, 2003

Combined Expression of Genetic Adjuvants Via mRNA Electroporation Exerts Multiple Immunostimulatory Effects on Antitumor T Cells

scientific article published on 01 February 2019

Extracellular matrix constituents interfere with Newcastle disease virus spread in solid tissue and diminish its potential oncolytic activity ⬇️

scientific article published on May 23, 2012

Human T cell crosstalk is induced by tumor membrane transfer

scientific article (publication date: 2015)

Immune Monitoring of Patients Treated With a Whole-Cell Melanoma Vaccine Engineered to Express 4-1BBL.

scientific article published on 25 August 2016

Imprinting of lymphocytes with melanoma antigens acquired by trogocytosis facilitates identification of tumor-reactive T cells

scientific article published on 26 April 2013

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

scientific article (publication date: 30 June 2011)

MHC class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4(+) T lymphocytes that cross-react with primary and metastatic uveal melanoma cells

scientific article published on May 2007

Membrane-attached Cytokines Expressed by mRNA Electroporation Act as Potent T-Cell Adjuvants

scientific article published on February 2016

Molecular detection of MART-1, tyrosinase and MIA in peripheral blood, lymph nodes and metastatic sites of stage III/IV melanoma patients

scientific article published on October 2004

Mucosal melanoma of the female genital tract is a multifocal disorder

scientific article

Neurologic complications of immune checkpoint inhibitors.

scientific article published on 13 January 2018

Ocular melanoma metastasizing to intra-abdominal lymph nodes

scientific article published on 16 May 2013

Pathways and therapeutic targets in melanoma

scientific article

Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006).

scientific article

Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma.

scientific article published on 27 October 2016

Potent Activation of Human T Cells by mRNA Encoding Constitutively Active CD40

article

Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors

scientific article

Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression

scientific article published on March 2007

Recombinant hydrophilic human gp100: uptake by dendritic cells and stimulation of autologous CD8+ lymphocytes from melanoma patients

scientific article published on 01 July 2004

SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint

scientific article published on 03 March 2020

Soluble SLAMF6 Receptor Induces Strong CD8+ T-cell Effector Function and Improves Anti-melanoma Activity In Vivo

scientific article published on 5 January 2018

Spontaneous Activation of Antigen-presenting Cells by Genes Encoding Truncated Homo-Oligomerizing Derivatives of CD40

scientific article published on 01 February 2017

The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin

scientific article published on January 2010

The role of immune checkpoint receptors in the malignant phenotype of cutaneous T cell lymphoma

scientific article published in 2022

Transcutaneous immunization with hydrophilic recombinant gp100 protein induces antigen-specific cellular immune response ⬇️

scientific article published on September 18, 2010

Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients

scientific article published in May 2017

Trogocytosis Is a Gateway to Characterize Functional Diversity in Melanoma-Specific CD8+ T Cell Clones ⬇️

scientific article published on December 7, 2011

Ultraviolet radiation and cutaneous carcinogenesis

scientific article published on January 2007

Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells.

scientific article

Viral carcinogenesis in skin cancer

scientific article published on January 2007

Widespread morbilliform rash due to sorafenib or vemurafenib treatment for advanced cancer; experience of a tertiary dermato-oncology clinic

scientific article published on 29 January 2016

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