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List of works by Saverio Cinti

A large proportion of mediastinal and perirenal visceral fat of Siberian adult people is formed by UCP1 immunoreactive multilocular and paucilocular adipocytes

scientific article published on 18 December 2019

ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes

scientific article

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

scientific article published on 21 August 2011

Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex

scientific article published on 27 June 2016

Activation of transcription factors STAT1 and STAT5 in the mouse median eminence after systemic ciliary neurotrophic factor administration.

scientific article

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.

scientific article published on 16 October 2017

Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue

scientific article published in Nature Communications

Adipose organ nerves revealed by immunohistochemistry

scientific article

Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance.

scientific article

Adult epicardial fat exhibits beige features

scientific article published on 3 July 2013

Author Correction: Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD.

scientific article published on 11 December 2017

Beta 3-adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat

scientific article published on 01 February 2003

Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes

scientific article published on 12 November 2019

Biomarkers of Browning in Cold Exposed Siberian Adults

scientific article published on 22 July 2020

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis

scientific article published on 18 June 2020

Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation.

scientific article published on 29 March 2018

Brush cells in the human duodenojejunal junction: an ultrastructural study

scientific article

CL316,243 and cold stress induce heterogeneous expression of UCP1 mRNA and protein in rodent brown adipocytes

scientific article published on 01 January 2002

COVID-19 and Hartnup disease: an affair of intestinal amino acid malabsorption

scientific article published on 20 July 2020

COVID-19 and fat embolism: a hypothesis to explain the severe clinical outcome in people with obesity

scientific article published on 08 June 2020

Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21.

scientific article published on January 2012

Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity

scientific article

Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus

scientific article published on 21 May 2020

Complement abnormalities in acquired lipodystrophy revisited

scientific article published on 14 October 2008

Constitutive expression of ciliary neurotrophic factor in mouse hypothalamus.

scientific article published on 28 March 2012

Convertible visceral fat as a therapeutic target to curb obesity.

scientific article published on 11 March 2016

Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function

scientific article published on 15 September 2006

Distribution and development of brown adipocytes in the murine and human adipose organ

scientific article published on April 2010

Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets.

scientific article published on 24 July 2007

Endothelial cells of adipose tissues: a niche of adipogenesis

scientific article published in August 2012

Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus

scientific journal article

Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo

scientific article published on January 2002

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

scientific article published on 28 May 2016

Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue

scientific article published on 23 November 2013

Gastric ghrelin cells in obese patients are hyperactive

scientific article published on 23 November 2020

Haploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance, and hepatosteatosis in mice.

scientific article published on 5 May 2009

Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

scientific article published on 15 January 2014

Human White Adipocytes Convert Into "Rainbow" Adipocytes In Vitro.

scientific article

Human dedifferentiated adipocytes show similar properties to bone marrow-derived mesenchymal stem cells

scientific article

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma

scientific article published in April 2003

Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation

scientific article published on 24 January 2013

In vivo phenotyping of the ob/ob mouse by magnetic resonance imaging and 1H-magnetic resonance spectroscopy.

scientific article

In vivo physiological transdifferentiation of adult adipose cells

scientific article published on 01 November 2009

Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice

scientific article

Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion

scientific article

Irisin and musculoskeletal health

scientific article

Irisin enhances osteoblast differentiation in vitro

scientific article published on 04 March 2014

Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice

scientific article

Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD.

scientific article published on 22 September 2017

Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice

scientific article published on October 2006

Leptin-dependent STAT3 phosphorylation in postnatal mouse hypothalamus.

scientific article published on 10 April 2008

Mammary alveolar epithelial cells convert to brown adipocytes in post-lactating mice

scientific article published on 12 February 2017

Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis

scientific article published on 10 August 2020

Melatonin Supplementation Decreases Hypertrophic Obesity and Inflammation Induced by High-Fat Diet in Mice

scientific article published on 05 November 2019

MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes

scientific article published on 01 June 2014

Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high-fat-diet-fed mice

scientific article published on 07 May 2014

Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion.

scientific article published in April 2018

Molecular and functional characterization of human bone marrow adipocytes

scientific article published on 19 February 2013

Molecular aspects of adipoepithelial transdifferentiation in mouse mammary gland.

scientific article published on October 2014

Morphology of ferret subcutaneous adipose tissue after 6-month daily supplementation with oral beta-carotene

scientific article published on 17 November 2004

Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery

scientific article published on 21 August 2017

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

scientific article published on 15 June 2009

Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis.

scientific article published on 08 July 2013

Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha.

scientific article

Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus

scientific article published on 27 December 2013

Optogenetic-induced sympathetic neuromodulation of brown adipose tissue thermogenesis

scientific article published on 23 December 2019

Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice

scientific article published on 20 June 2019

Parathyroid glands in primary hyperparathyroidism: an ultrastructural morphometric study of 25 cases

scientific article published on July 1, 1992

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC

scientific article

Perinatal expression of leptin in rat stomach

scientific article published on 01 January 2002

Plasticity of human dedifferentiated adipocytes toward endothelial cells.

scientific article

Possible involvement of inflammatory/reparative processes in the development of uterine fibroids

scientific article published on 27 November 2015

Presence and distribution of cholinergic nerves in rat mediastinal brown adipose tissue.

scientific article

Publisher Correction: Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery.

scientific article published on 22 May 2018

Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting.

scientific article published in June 2005

Remodeling of white adipose tissue after retinoic acid administration in mice

scientific article published on 13 July 2006

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.

scholarly article

Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland

scholarly article

Sema3A and neuropilin-1 expression and distribution in rat white adipose tissue

scientific article

Sensory or sympathetic white adipose tissue denervation differentially affects depot growth and cellularity

scientific article published on 18 November 2004

Steatosis associated with immotile cilia syndrome: an unrecognized relationship?

scientific article published on 01 March 1992

Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis

scientific article

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform

scientific article

The myokine irisin increases cortical bone mass.

scientific article

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue.

scientific article

The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells

scientific article published on February 2012

Thymus uncoupling protein 1 is exclusive to typical brown adipocytes and is not found in thymocytes

scientific article published on 13 November 2006

UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity

scientific article

Ultrastructural modifications in one case of hairy cell leukemia during alpha-interferon therapy

scientific article published on June 30, 1992

Unusual ultrastructural features in microvillous inclusion disease: A report of two cases

scientific article published on 12 April 2006

Visceral fat inflammation and fat embolism are associated with lung's lipidic hyaline membranes in subjects with COVID-19

scientific article published on 26 January 2022

Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling

scientific article

White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation.

scientific article published on 29 June 2006

White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ

scientific article published on 10 April 2014

White, brown, beige and pink: A rainbow in the adipose organ

scientific article published in 2019

White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma

scientific article published on 20 February 2013

Zic1 mRNA is transiently upregulated in subcutaneous fat of acutely cold-exposed mice

scientific article published on 20 October 2018

p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.

scientific article published on 17 November 2015

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

scientific article published on 28 October 2020