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List of works by Andrea J. Pruijssers

A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection

scientific article published on 01 March 2019

Advocating for mutually beneficial access to shelved compounds

scientific article published on 23 May 2018

Age-dependent susceptibility to reovirus encephalitis in mice is influenced by maturation of the type-I interferon response.

scientific article published on 24 January 2018

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

scientific article published on 14 July 2020

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus

scientific article (preprint)

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

scientific article published on 06 April 2020

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

scientific article

Apoptosis induction influences reovirus replication and virulence in newborn mice

scientific article

Bid regulates the pathogenesis of neurotropic reovirus. ⬇️

scientific article

Characterization and kinetic analysis of protein tyrosine phosphatase-H2 from Microplitis demolitor bracovirus ⬇️

scientific article published on August 5, 2010

Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis

scientific article published on 28 February 2019

Endothelial JAM-A promotes reovirus viremia and bloodstream dissemination

scientific article

Infection by a symbiotic polydnavirus induces wasting and inhibits metamorphosis of the moth Pseudoplusia includens

scientific article published on September 2009

Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance

scientific article published on 12 May 2010

Intestinal Microbiota Promote Enteric Virus Replication and Systemic Pathogenesis ⬇️

scientific article published on October 14, 2011

Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

scientific article published on 28 April 2022

Nucleoside analogues for the treatment of coronavirus infections

scientific article published in April 2019

PTP-H2 and PTP-H3 from Microplitis demolitor Bracovirus localize to focal adhesions and are antiphagocytic in insect immune cells

scientific article published on 22 November 2006

Protein tyrosine phosphatase-H2 from a polydnavirus induces apoptosis of insect cells

scientific article

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

scientific article published on 07 July 2020

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

scientific article published on 28 April 2020

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.

scientific article published on April 2017

Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection

scientific article published on 7 March 2018

Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection

scientific article published on 10 October 2019

Small-Molecule Antiviral β-d--Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3.

scientific article

Utilization of Sialylated Glycans as Coreceptors Enhances the Neurovirulence of Serotype 3 Reovirus ⬇️

scientific article published on October 3, 2012

Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18

scientific article

When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data

scientific article published in December 2017

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