Search filters

List of works by Ana C. Anderson

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

scientific article published on September 2016

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

scientific article published in November 2017

A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiation

scientific article published on 26 February 2015

A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells

scientific article published on 25 January 2012

An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets

scientific article published on 01 November 2020

An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction

scientific article

Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion.

scientific article

Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy.

scientific article published on 9 November 2017

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis

scientific article published on 01 October 2007

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

scientific journal article

Challenges and opportunities in cancer immunotherapy: a Society for Immunotherapy of Cancer (SITC) strategic vision

scientific article published on 19 June 2024

Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells

scientific article published on 08 January 2019

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

scientific article

Coinhibitory receptors and CD8 T cell exhaustion in chronic infections

scientific article published on September 2014

Combination immunotherapy: Where do we go from here?

scientific article published on 18 August 2015

Comment on "Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection".

scientific article published in July 2014

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

scientific article published on 25 November 2020

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells ⬇️

scientific article published on June 7, 2012

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

scientific article

Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

scientific article published on 16 March 2016

Cutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC.

scientific article published on December 2008

Decoding T cell state-specific regulomes in cancer

scientific article published in June 2024

Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.

scientific article

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

scientific article

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

scientific article published on 14 December 2021

Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity

scientific article published on 12 March 2020

Editorial: Tim-3 puts on the brakes ⬇️

scientific article published on 01 February 2012

Emerging Tim-3 functions in antimicrobial and tumor immunity

scientific article published on 21 June 2011

Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

scientific article published on 01 September 2020

Endogenous T Cell Receptor Rearrangement Represses Aggressive Central Nervous System Autoimmunity in a TcR-Transgenic Model on the Non-Obese Diabetic Background

scientific article published on 01 January 2019

Erratum: Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL–10 expression and T-cell dysfunction

scientific article published in Nature Communications

Expression of self-antigen in the thymus: a little goes a long way.

scientific article published on December 2003

Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity.

scientific article published on 2 March 2018

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013.

scientific article

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

scientific journal article

IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice

scientific article published in July 2004

IL-1β promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation

scientific article published on 13 March 2013

Immune checkpoints in central nervous system autoimmunity.

scientific article published on July 2012

Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1.

scientific article published in June 2005

Induction and transcriptional regulation of the co-inhibitory gene module in T cells

scientific article published in Nature

Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling

scientific article published in 2022

Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19

scientific article published on 01 April 2020

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation

scientific article published on 13 February 2024

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.

scientific article published on May 2016

Mechanisms of TIGIT-driven immune suppression in cancer

Melanoma progression is associated with NK cell exhaustion.

scientific article published on 6 November 2014

Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background

scientific article published on 05 September 2007

Molecular Dissection of CD8+ T-Cell Dysfunction.

scientific article published on 26 June 2017

NRP1 cripples immunological memory

scientific article published on 28 July 2020

New Clones on the Block

scientific article published on 01 October 2019

New roles for TIM family members in immune regulation

scientific article

PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8⁺ T cells induced by melanoma vaccines

scientific article published on 16 December 2013

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis

scientific article published on 13 August 2021

Presence of Tim 3 + and PD ‐1 + CD8 + T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and distinct clinicopathological features

scientific article published on 9 April 2022

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells ⬇️

scientific article published on September 20, 2010

Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells

scientific journal article

Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade

scientific article

Revolutionizing Cancer Immunology: The Power of Next-Generation Sequencing Technologies

scientific article published on 01 February 2019

Role of Th1 and Th17 cells in organ-specific autoimmunity.

scientific article published on 27 May 2008

Spatial determinants of CD8 T cell differentiation in cancer

scientific article published in August 2022

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

scientific article

T cell factor 1: A master regulator of the T cell response in disease

scientific article published on 01 November 2020

T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire

scientific article

T-bet, a Th1 transcription factor regulates the expression of Tim-3.

scientific article

TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy

scientific article

TIGIT predominantly regulates the immune response via regulatory T cells.

scientific article

TIM-3 and its regulatory role in immune responses

scientific article

TIM-3 in autoimmunity

scientific article published on 2 October 2006

TIM-3 restrains anti-tumour immunity by regulating inflammasome activation

scientific article published on 09 June 2021

TIM-4 expressed on APCs induces T cell expansion and survival

scientific article

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

scientific article

TIM3 comes of age as an inhibitory receptor

scientific article published on 01 November 2019

TIM3(+)FOXP3(+) regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer

scientific article published on April 2013

Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor Immunity

scientific article published on 07 November 2019

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

scientific article

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

scientific article published on 30 May 2011

The Non-Obese Diabetic Mouse Strain as a Model to Study CD8(+) T Cell Function in Relapsing and Progressive Multiple Sclerosis

scientific article

The Notch regulator Numb links the Notch and TCR signaling pathways

scientific article published in January 2005

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

scientific article

The dynamics of effector T cells and Foxp3+ regulatory T cells in the promotion and regulation of autoimmune encephalomyelitis

scientific article published on 3 October 2007

Tim protein structures reveal a unique face for ligand binding

scientific article published on 01 March 2007

Tim-3 finds its place in the cancer immunotherapy landscape

scientific article published on 01 June 2020

Tim-3, a negative regulator of anti-tumor immunity ⬇️

scientific article published on 04 January 2012

Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.

scientific article

Tim-3: an emerging target in the cancer immunotherapy landscape

scientific article

Tim3 binding to galectin-9 stimulates antimicrobial immunity

scientific journal article

Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma.

scientific article published on 6 March 2018

Tumors recycle glucocorticoids to drive Treg-mediated immunosuppression

scientific article published on 15 September 2023

Up-regulation of gene related to anergy in lymphocytes is associated with Notch-mediated human T cell suppression

scientific article

Paulina is supported by:

About Paulina

Help