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List of works by Kunihiro Matsumoto

A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation

A mechanism for the suppression of interleukin-1-induced nuclear factor kappaB activation by protein phosphatase 2Ceta-2.

scientific article published on 14 September 2009

A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance

scholarly article

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

scientific article published on 6 March 2003

Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells

scientific article

Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells

scientific article published on 24 June 2004

An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans

scientific article published on 21 December 2003

Axon Regeneration Is Regulated by Ets-C/EBP Transcription Complexes Generated by Activation of the cAMP/Ca2+ Signaling Pathways

scientific article

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways ⬇️

scientific article published on June 13, 2011

Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans

scientific article published on 21 January 2016

C. elegans Tensin Promotes Axon Regeneration by Linking the Met-like SVH-2 and Integrin Signaling Pathways

scientific article published on 20 May 2019

Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor

scientific article published on 29 January 2021

Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation

scientific article

Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity

scientific article published on 30 November 2007

Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi.

scientific article published on 8 February 2016

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade

scientific article (publication date: March 2003)

Delta1 family members are involved in filopodial actin formation and neuronal cell migration independent of Notch signaling.

scientific article

Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans ⬇️

scientific article published on August 3, 2011

EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR ⬇️

scientific article published on February 15, 2012

Elucidation of the c-Jun N-terminal kinase pathway mediated by Estein-Barr virus-encoded latent membrane protein 1.

scientific article

Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32.

scientific article

Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling

scientific article

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

scientific article

Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species

scientific article published on 13 February 2012

Essential function for the kinase TAK1 in innate and adaptive immune responses

scientific article published on 25 September 2005

Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos

scientific article published on 12 October 2007

Forgetting in C. elegans is accelerated by neuronal communication via the TIR-1/JNK-1 pathway

scientific article published on 21 March 2013

Homodimerization of Nemo-like kinase is essential for activation and nuclear localization

scientific article published on 30 November 2010

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

scientific article

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

scientific article published on 16 January 2004

LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its effector RILP

scientific article published on 03 June 2019

LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

scientific article published on 16 September 2015

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends

scientific article published on 20 November 2014

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends.

scientific article

LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans

scientific article

Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor ⬇️

scientific article published on January 18, 2011

MAP kinase cascades regulating axon regeneration in C. elegans

scientific article published on January 2015

N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans

scientific article published on 01 August 2019

NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells ⬇️

scientific article published on February 28, 2012

Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin

scientific article published on 16 October 2009

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex

scientific article published on 31 January 2010

Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways

scientific article

Osmotic stress blocks NF-kappaB-dependent inflammatory responses by inhibiting ubiquitination of IkappaB.

scientific article

PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

scientific article published on 20 July 2015

Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration

scientific article published in Nature Communications

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans

scientific article (publication date: April 2010)

Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway

scientific article

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

scientific article

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6

scientific article

Regulation of ERK activity duration by Sprouty contributes to dorsoventral patterning

scientific article published in January 2009

Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins

scientific article

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

scientific article

Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

scientific article

Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)

scientific article

Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway

scientific article published on 22 September 2008

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

scientific article

Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

scientific article

Roles of MAP kinase cascades in Caenorhabditis elegans

scientific article published in July 2004

SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans

scientific article

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

scientific article

Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty

scientific article

Signal transduction cascades in axon regeneration: insights from C. elegans

scientific article published on 14 February 2017

Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts

scientific article

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

scientific article

TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms

scientific article

TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation

scientific article published on 2 February 2007

TAK1 binding protein 2 is essential for liver protection from stressors

scientific article (publication date: 2014)

TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus.

scientific article published on 16 March 2016

TAK1 is a central mediator of NOD2 signaling in epidermal cells

scientific article published on 26 October 2007

TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.

scientific article published on 30 January 2006

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

scientific article

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

scientific article (publication date: 7 February 2003)

TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

scientific article

TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation

scientific article published on February 2014

TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity

scientific article published on 7 July 2008

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

scientific article

TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling

scientific article published on October 2008

TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway

scientific article published in May 2005

TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor

scientific article published on 08 August 2019

TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium

scientific article published on 20 September 2010

TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts

scientific article published on March 2011

Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis

scientific journal article

The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon Regeneration

scientific article

The C. elegans HGF/plasminogen-like protein SVH-1 has protease-dependent and -independent functions

scientific article published on 20 November 2014

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

scientific article published on 15 September 2005

The C. elegans BRCA2-ALP/Enigma Complex Regulates Axon Regeneration via a Rho GTPase-ROCK-MLC Phosphorylation Pathway

scientific article published on 01 August 2018

The Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex

scientific article

The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress response

scientific article

The Core Molecular Machinery Used for Engulfment of Apoptotic Cells Regulates the JNK Pathway Mediating Axon Regeneration in Caenorhabditis elegans

scientific article

The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans

scientific article

The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

scientific article

The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline

scientific article (publication date: 2009)

The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade ⬇️

scientific article published on March 4, 2012

Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway

scientific article

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

scientific article

Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

scientific article

[MAP kinase cascade regulating synaptic vesicle localization in C. elegans as a model animal]

scientific article published on 01 September 2002

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