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List of works by Toshifumi Hibi

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Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011

scientific article published on 05 January 2012
A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

scientific article
Subcutaneous Golimumab Induces Clinical Response and Remission in Patients With Moderate-to-Severe Ulcerative Colitis

scientific article published on June 2, 2013
Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis

scientific article published on June 2008
Lack of common NOD2 variants in Japanese patients with Crohn's disease

scientific article
Development of the Crohn's disease digestive damage score, the Lémann score

scientific article published on 28 November 2010
Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease

scientific article
Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion

scientific article
Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease

scientific article published in June 2010
Damaged epithelia regenerated by bone marrow-derived cells in the human gastrointestinal tract

scientific article published on 26 August 2002
Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health

scientific article published on June 5, 2011
Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease

scientific article
Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients

scientific article published on 11 December 2006
Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells

scientific article published on December 2012
A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice

scientific article published in June 2013
Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease

scientific article published on August 2008
Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

scientific article
Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

scientific article published on 01 November 2005
Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion.

scientific article published on June 2009
A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitis

scientific article published on 25 April 2008
Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column

scientific article
Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis

scientific article published on September 1, 2011
Novel pathophysiological concepts of inflammatory bowel disease

scientific article
Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats

scientific article published on August 2004
Granulocytapheresis is useful as an alternative therapy in patients with steroid-refractory or -dependent ulcerative colitis

scientific article published in May 2004
Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice

scientific article published in August 2008
Leukocytapheresis in ulcerative colitis: results of a multicenter double-blind prospective case-control study with sham apheresis as placebo treatment

scientific article published in June 2005
Treatment of ulcerative colitis by feeding with germinated barley foodstuff: first report of a multicenter open control trial

scientific article
Animal models of inflammatory bowel disease

scientific article
Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease

scientific article (publication date: 2012)
TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease

scientific article published in April 2010
A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells

scientific article published on 10 October 2011
Evidence-based clinical practice guidelines for Crohn’s disease, integrated with formal consensus of experts in Japan

scientific article published on October 23, 2012
Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis

scientific article published on January 1, 2003
An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis as compared with routine weekly treatment

scientific article
Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability

scientific article published on 10 July 2009
Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset

scientific article published on 27 January 2010
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease

scientific article published on May 2013
Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells

scientific article published on 21 May 2007
Helicobacter Pylori Eradication Therapy

scientific article published on April 1, 2010
Evidence-based clinical practice guidelines for inflammatory bowel disease.

scientific article published on 10 February 2018
Adalimumab for the induction and maintenance of clinical remission in Japanese patients with Crohn's disease

scientific article published on August 26, 2011
Efficacy and safety of adalimumab in Japanese patients with moderately to severely active ulcerative colitis

scientific article published on 24 December 2013
NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity

scientific article published on March 7, 2011
Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cells

scientific article
Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages.

scientific article published on 7 October 2008
The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.

scientific article
Development of consensus statements for the diagnosis and management of intestinal Behçet's disease using a modified Delphi approach

scientific article published on 25 September 2007
Nonpathogenic Escherichia coli strain Nissle1917 prevents murine acute and chronic colitis.

scientific article
First trough level of infliximab at week 2 predicts future outcomes of induction therapy in ulcerative colitis-results from a multicenter prospective randomized controlled trial and its post hoc analysis

scientific article published on 11 July 2015

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