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List of works by Toshifumi Hibi

"Candidatus Helicobacter heilmannii" from a cynomolgus monkey induces gastric mucosa-associated lymphoid tissue lymphomas in C57BL/6 mice

scientific article

3. Viral Infection of the Small Intestine

scientific article published on January 10, 2011

5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis

5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis

scientific article published on 01 April 2012

6. Progress in Management of Crohn's Disease

scientific article published on January 10, 2011

A Case of IgA-related Enteropathy Complicated with Gastrointestinal Bleeding and Progressive IgA Nephropathy: A Possible Variant Henoch-Schönlein Purpura?

scientific article published on August 13, 2010

A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter

scientific article (publication date: November 2015)

A case of Behçet's disease accompanied by colitis with longitudinal ulcers and granuloma

scientific article published on January 2002

A case of Crohn's disease complicated with hepatocellular carcinoma

scientific article published in July 2003

A case of advanced gastric cancer with lymphangitis carcinomatosa after operation of Krukenberg tumor treated by TS-1 plus CPT-11 as third-line chemotherapy

scientific article published in August 2005

A case of beef tapeworm (Taenia saginata) infection observed by using video capsule endoscopy and radiography (with videos)

scientific article published on September 1, 2011

A case of intestinal Behçet's disease treated with infliximab monotherapy who successfully maintained clinical remission and complete mucosal healing for six years

scientific article published on 15 August 2012

A case of pneumatosis cystoides intestinalis induced by steroid pulse therapy for severe acute hepatitis B

scientific article published on July 1, 2011

A case of small intestine type steroid-naïve Crohn disease in which osteomalacia was diagnosed by fractures on the transcervical bone

scientific article published on 01 December 2012

A case of type 4 gastric cancer, diagnosed after operation for Krukenberg's tumor, treated by TS-1 plus low-dose cisplatinum

scientific article

A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells

scientific article published on 10 October 2011

A large-scale, prospective, observational study of leukocytapheresis for ulcerative colitis: treatment outcomes of 847 patients in clinical practice

scientific article published on 18 February 2014

A multicenter study of the efficacy and safety of leukocytapheresis therapy without concomitant systemic steroid treatment in patients with active ulcerative colitis

scientific article published on 01 April 2011

A multicenter, retrospective, observational study of the clinical outcomes and risk factors for relapse of ulcerative colitis at 1 year after leukocytapheresis

scientific article published on 08 June 2017

A new eradication resistance index as a predictor of metronidazole-containing second-line treatment of Helicobacter pylori

scientific article published on 21 December 2007

A new prognostic formula for adult acute liver failure using computer tomography-derived hepatic volumetric analysis

scientific article

A novel apoptosis-inducing monoclonal antibody (anti-LHK) against a cell surface antigen on colon cancer cells

scientific article published in October 2005

A pilot open-labeled prospective randomized study between weekly and intensive treatment of granulocyte and monocyte adsorption apheresis for active ulcerative colitis.

scientific article published on 24 February 2008

A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

scientific article

A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitis

scientific article published on 25 April 2008

A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice

scientific article published in June 2013

A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.

scientific article

AICAR, an AMPK activator, has protective effects on alcohol-induced fatty liver in rats

scientific article

Aberrant expressions of aquaporin-1 in association with capillarized sinusoidal endothelial cells in cirrhotic rat liver

scientific article published on 26 March 2010

Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

scientific article published on 01 November 2005

Acetaldehyde inhibits the formation of retinoic acid from retinal in the rat esophagus

scientific article published in January 2006

Acid suppression by proton pump inhibitors enhances aquaporin-4 and KCNQ1 expression in gastric fundic parietal cells in mouse.

scientific article published in May 2010

Acoustic radiation force impulse imaging for assessing graft fibrosis after pediatric living donor liver transplantation: a pilot study

scientific article published on 21 September 2013

Activated hepatic stellate cells mediate the differentiation of macrophages

scientific article published on 29 October 2012

Acute intrahepatic cholestasis accompanied with Chlamydophila pneumoniae infection

scientific article published on March 23, 2011

Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells

scientific article published on 18 March 2014

Adalimumab Monotherapy and a Combination with Azathioprine for Crohn's Disease: A Prospective, Randomized Trial

scientific article published on 26 August 2016

Adalimumab for the induction and maintenance of clinical remission in Japanese patients with Crohn's disease

scientific article published on August 26, 2011

Adsorptive granulocyte and monocyte apheresis for refractory Crohn's disease: an open multicenter prospective study

scientific article published on 01 December 2004

Advanced gallbladder cancer that showed complete response to gemcitabine plus S-1 chemotherapy

scientific article published on 01 July 2011

Advances in genomic research on hepatitis C virus with a useful tool, replicon system

scientific article published on June 2008

Alcoholic liver diseases and hepatitis virus C in Japan

scientific article

Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori

scientific article published on 26 August 2008

Alteration of angiogenesis in Helicobacter heilmannii-induced mucosa-associated lymphoid tissue lymphoma: interaction with c-Met and hepatocyte growth factor

scientific article published on December 2014

Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis

scientific article published on 01 February 2003

Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion

scientific article

An antioxidant resveratrol significantly enhanced replication of hepatitis C virus

scientific article (publication date: 14 January 2010)

An inverse association between serum gamma glutamyl transpeptidase activity and Breslow's Lifestyle Index; its practical application for screening of subjects with unhealthy lifestyles

scientific article published in May 2006

An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis as compared with routine weekly treatment.

scientific article

Analysis of Toll-like receptor 2, 4, 6 and 9 genome DNA mutations in patients with tractable and intractable gastric mucosal diseases

scientific article published on 01 January 2006

Analysis of the differences in structural chromosomal aberrations of the gastric mucosa between H. pylori positive and negative gastric cancer patients: involvement of H. pylori in the onset of gastric cancer and examination of the mechanism in gast

scientific article published on 01 December 2006

Anchor clip technique helps in easy prevention of post-polypectomy hemorrhage of large colonic polyps

scientific article published on 01 October 2010

Animal models of inflammatory bowel disease

scientific article

Anti-high mobility group box 1 and box 2 non-histone chromosomal proteins (HMGB1/HMGB2) antibodies and anti-Saccharomyces cerevisiae antibodies (ASCA): accuracy in differentially diagnosing UC and CD and correlation with inflammatory bowel disease p

scientific article published on May 30, 2012

Antibiotics directly induce apoptosis in B cell lymphoma cells derived from BALB/c mice.

scientific article published on November 2004

Anticoagulation therapy dramatically improved severe sigmoiditis with findings resembling inflammatory bowel disease, which was caused by mesenteric venous thrombosis.

scientific article published on 13 November 2012

Aortic carboxypeptidase-like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis

scientific article published on 19 March 2018

Applicability of second-generation colon capsule endoscope to ulcerative colitis: a clinical feasibility study.

scientific article published in July 2013

Aquaporin‐1 associated with hepatic arterial capillary proliferation on hepatic sinusoid in human cirrhotic liver

scientific article published on July 29, 2011

Asia Pacific Consensus Statements on Crohn's disease. Part 1: Definition, diagnosis, and epidemiology: (Asia Pacific Crohn's Disease Consensus--Part 1).

scientific article published on 25 March 2015

Asia-Pacific consensus statements on Crohn's disease. Part 2: Management.

scientific article published on 25 March 2015

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 1: risk assessment

scientific article published on 18 January 2018

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 2: Management

scientific article published on 10 October 2017

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 2: management

scientific article published on 18 January 2018

Asian Organization for Crohn's and Colitis and Asian Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 1: Risk assessment

scientific article published on 10 October 2017

Association between the interleukin-1 receptor antagonist polymorphism and ulcerative colitis with younger age at diagnosis

scientific article published on November 15, 2003

Association of an overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis with cytomegalovirus infection

scientific article published on 24 May 2011

Association of pseudomembranous colitis with Henoch-Schönlein purpura

scientific article published in June 2005

Association of the -173 G/C polymorphism of the macrophage migration inhibitory factor gene with ulcerative colitis

scientific article published in January 2004

Attenuating effect of Myakuryu on mesenteric microcirculatory disorders induced by ischemia and reperfusion

scientific article published in January 2006

Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors

scientific article published on 24 August 2012

Autoimmune hepatitis associated with pulmonary arterial hypertension

scientific article published on 17 November 2008

Bile acids increase levels of microRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis.

scientific article published on 8 August 2013

Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway

scientific article published in June 2012

Blatchford scoring system is a useful scoring system for detecting patients with upper gastrointestinal bleeding who do not need endoscopic intervention

scientific article published on 01 September 2007

Blinded nonrandomized comparative study of gastric examination with a magnetically guided capsule endoscope and standard videoendoscope

scientific article published on 09 December 2011

Bouveret's syndrome with a concomitant incidental T1 gallbladder cancer

scientific article published on 4 September 2010

Butter feeding enhances TNF-alpha production from macrophages and lymphocyte adherence in murine small intestinal microvessels

scientific article

C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.

scientific article published on 31 May 2013

C-reactive protein is an indicator of serum infliximab level in predicting loss of response in patients with Crohn's disease

scientific article published on 20 April 2013

CCL2-Induced Migration and SOCS3-Mediated Activation of Macrophages Are Involved in Cerulein-Induced Pancreatitis in Mice

scientific article published on January 13, 2012

CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis

scientific article published on 10 November 2011

CCR9+ macrophages are required for eradication of peritoneal bacterial infections and prevention of polymicrobial sepsis

scientific article published on 4 July 2012

CXCL12 and CCL20 play a significant role in mucosal T-lymphocyte adherence to intestinal microvessels in mice

scientific article

Can Helicobacter pylori-associated dyspepsia be categorized as functional dyspepsia?

scientific article published on April 2011

Caveolin-1 and Rac regulate endothelial capillary-like tubular formation and fenestral contraction in sinusoidal endothelial cells

scientific article published on 02 December 2008

Changes in regulatory molecules for lymphangiogenesis in intestinal lymphangiectasia with enteric protein loss

scientific article published on 14 November 2007

Characterization of structures with T-lymphocyte aggregates in ileal villi of Crohn's disease

scientific article published on 01 July 2002

Chemoresistance is associated with cancer stem cell-like properties and epithelial-to-mesenchymal transition in pancreatic cancer cells.

scientific article

Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease

scientific article

Clinical features of chronic enteropathy associated with SLCO2A1 gene: a new entity clinically distinct from Crohn's disease

scientific article published on 8 January 2018

Clinical impact of a newly developed capsule endoscope: usefulness of a real-time image viewer for gastric transit abnormality

scientific article published on 29 March 2008

Clinical results of endoscopic hemostasis using a short transparent hood and short hemoclips for non-variceal upper gastrointestinal bleeding

scientific article published in April 2009

Clinical significance of human intestinal spirochetosis: a retrospective study

scientific article published on January 2017

Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.

scientific article

Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.

scientific article published in July 2007

Clinical trial: effects of an oral preparation of mesalazine at 4 g/day on moderately active ulcerative colitis. A phase III parallel-dosing study

scientific article published on September 29, 2010

Colon neoplastic cells do not originate from bone marrow-derived cells after sex-mismatched bone marrow transplantation

scientific article published on September 1, 2012

Comparison of efficacies of once-daily dose multimatrix mesalazine and multiple-dose mesalazine for the maintenance of remission in ulcerative colitis: a randomized, double-blind study

scientific article

Comparison of efficacy of multimatrix mesalazine 4.8 g/day once-daily with other high-dose mesalazine in active ulcerative colitis: a randomized, double-blind study

scientific article

Comparison of efficacy of once daily multimatrix mesalazine 2.4 g/day and 4.8 g/day with other 5-aminosalicylic acid preparation in active ulcerative colitis: a randomized, double-blind study.

scientific article

Complete mucosal healing of distal lesions induced by twice-daily budesonide 2-mg foam promoted clinical remission of mild-to-moderate ulcerative colitis with distal active inflammation: double-blind, randomized study

scientific article published on 4 August 2017

Compound Danshen injection improves endotoxin-induced microcirculatory disturbance in rat mesentery

scientific article

Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011

scientific article published on 05 January 2012

Computer-Aided Prediction of Long-Term Prognosis of Patients with Ulcerative Colitis after Cytoapheresis Therapy.

scientific article published on 25 June 2015

Conception and pregnancy outcome in women with inflammatory bowel disease: A multicentre study from Japan

scientific article published on March 11, 2011

Continuous low-dose irradiation by I-125 seeds induces apoptosis of gastric cancer cells regardless of histological origin.

scientific article published on 22 October 2013

Contribution of Irf-1 promoter polymorphisms to the Th1-type cell response and interferon-beta monotherapy for chronic hepatitis C

scientific article published on 01 May 2005

Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori.

scientific article published in May 2010

Correction to: Complete mucosal healing of distal lesions induced by twice-daily budesonide 2-mg foam promoted clinical remission of mild-to-moderate ulcerative colitis with distal active inflammation: double-blind, randomized study.

scientific article published on 13 October 2017

Correction: Vedolizumab in Japanese patients with ulcerative colitis: A Phase 3, randomized, double-blind, placebo-controlled study

Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis

scientific article published on July 30, 2011

Cross-sectional small intestinal surveillance of maintenance hemodialysis patients using video capsule endoscopy: SCHEMA study

scientific article published on 15 April 2016

Cyclooxygenase-2 inhibitor and interferon-beta synergistically induce apoptosis in human hepatoma cells in vitro and in vivo

scientific article published on 01 September 2006

Cytokine and anti-cytokine therapies for inflammatory bowel disease

scientific article

Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients.

scientific article published on 11 December 2006

DNMT1 and DNMT3b silencing sensitizes human hepatoma cells to TRAIL-mediated apoptosis via up-regulation of TRAIL-R2/DR5 and caspase-8.

scientific article published on 13 March 2010

Damaged epithelia regenerated by bone marrow-derived cells in the human gastrointestinal tract

scientific article published on 26 August 2002

Decreased Plasma Histidine Level Predicts Risk of Relapse in Patients with Ulcerative Colitis in Remission

scientific article published on 16 October 2015

Decreased levels of adiponectin in obese patients with gastroesophageal reflux evaluated by videoesophagography: possible relationship between gastroesophageal reflux and metabolic syndrome

scientific article published on 01 December 2008

Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs.

scientific article published on 11 August 2012

Development of consensus statements for the diagnosis and management of intestinal Behçet's disease using a modified Delphi approach

scientific article published on 25 September 2007

Development of the Crohn's disease digestive damage score, the Lémann score

scientific article published on 28 November 2010

Development of the Paris definition of early Crohn's disease for disease-modification trials: results of an international expert opinion process

scientific article published on December 2012

Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health

scientific article published on June 5, 2011

Dietary fat attenuates the benefits of an elemental diet in active Crohn's disease: a randomized, controlled trial

scientific article published in February 2003

Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages.

scientific article published on 7 October 2008

Difficulties in Taking Aminosalicylates for Patients With Ulcerative Colitis

scientific article published on January 1, 2012

Direct comparison of two different mesalamine formulations for the induction of remission in patients with ulcerative colitis: a double-blind, randomized study

scientific article

Direct comparison of two different mesalamine formulations for the maintenance of remission in patients with ulcerative colitis: a double-blind, randomized study

scientific article

Disability in inflammatory bowel diseases: developing ICF Core Sets for patients with inflammatory bowel diseases based on the International Classification of Functioning, Disability, and Health

scientific article published on January 2010

Disadvantages of peginterferon and ribavirin treatment in older patients with chronic hepatitis C: an analysis using the propensity score

scientific article published on 10 September 2011

Do immunosuppressants really work as maintenance therapy after the achievement of remission of severe ulcerative colitis?

scientific article

Does Helicobacter pylori attack ghrelin-producing cells?

scientific article published on 01 April 2005

Does an elemental diet affect operation and/or recurrence rate in Crohn?s disease in Japan?

scientific article published on January 1, 2003

Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis

scientific article published on September 1, 2011

Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils

scientific article published on 01 June 2005

Dual therapy for third-lineHelicobacter pylorieradication and urea breath test prediction

scientific article published on June 7, 2012

Dysregulated balance of retinoid-related orphan receptor γt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis.

scientific article

Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of Mongolian gerbils

scientific article published on 18 March 2009

Early intervention with adalimumab may contribute to favorable clinical efficacy in patients with Crohn's disease.

scientific article published on October 2014

Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn’s disease

scientific article published on July 5, 2011

Editorial: transperineal ultrasound in addition to a transabdominal ultrasound in ulcerative colitis-one more arrow in the quiver of non-invasive diagnostics. Authors' reply

scientific article published on 01 July 2020

Effect of Telmisartan or Losartan for Treatment of Nonalcoholic Fatty Liver Disease: Fatty Liver Protection Trial by Telmisartan or Losartan Study (FANTASY).

scientific article published on 13 August 2013

Effect of a herbal medicine on fatty liver in rats fed ethanol chronically

scientific article published in December 2009

Effect of dietary anti-urease immunoglobulin Y on Helicobacter pylori infection in Mongolian gerbils

scientific article published in February 2005

Effect of lansoprazole versus roxatidine on prevention of bleeding and promotion of ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia

scientific article published on July 30, 2011

Effect of long-term interferon therapy for refractory chronic hepatitis c: preventive effect on hepatocarcinogenesis.

scientific article

Effect of ursodeoxycholic acid and endoscopic sphincterotomy in long-term stenting for common bile duct stones

scientific article published in January 2013

Effects of a Helicobacter pylori eradication regimen on anti-platelet autoantibody response in infected and uninfected patients with idiopathic thrombocytopenic purpura

scientific article published on 07 September 2006

Effects of dihydroxylphenyl lactic acid on inflammatory responses in spinal cord injury

scientific article published on December 4, 2010

Effects of excessive ethanol consumption on the diagnosis of the metabolic syndrome using its clinical diagnostic criteria

scientific article published on 03 September 2007

Effects of the oral administration of mosapride citrate on capsule endoscopy completion rate

scientific article published on July 12, 2012

Effects of vedolizumab in Japanese patients with Crohn's disease: a prospective, multicenter, randomized, placebo-controlled Phase 3 trial with exploratory analyses

scientific article published on 13 December 2019

Efficacy and Safety of Oral Budesonide in Patients with Active Crohn's Disease in Japan: A Multicenter, Double-Blind, Randomized, Parallel-Group Phase 3 Study.

scientific article

Efficacy and safety of adalimumab in Japanese patients with moderately to severely active ulcerative colitis

scientific article published on 24 December 2013

Efficacy and safety of two pH-dependent-release mesalamine doses in moderately active ulcerative colitis: a multicenter, randomized, double-blind, parallel-group study

scientific article published on 26 January 2016

Efficacy and tolerability of oral budesonide in Japanese patients with active Crohn's disease: A multicentre, double-blind, randomized, parallel-group Phase II study

scientific article published on July 4, 2012

Efficacy of Bifidobacterium breve Fermented Milk in Maintaining Remission of Ulcerative Colitis

scientific article published on 15 February 2018

Efficacy of Indigo naturalis in a Multicenter Randomized Controlled Trial of Patients with Ulcerative Colitis

scientific article published on 22 November 2017

Efficacy of biological drugs in short-duration versus long-duration inflammatory bowel disease: a protocol for a systematic review and an individual-patient level meta-analysis of randomised controlled trials

Efficacy of infliximab for induction and maintenance of remission in intestinal Behçet's disease

scientific article

Efficacy of natural BALL-1 interferon-alpha treatment for patients with chronic hepatitis C and a possible enhancing effect of a twice-daily starting regimen with interferon-beta.

scientific article published in January 2006

Efficacy of sitafloxacin-based rescue therapy for Helicobacter pylori after failures of first- and second-line therapies.

scientific article published on 27 December 2011

Endoscopic and chromoendoscopic atlas featuring dysplastic lesions in surveillance colonoscopy for patients with long-standing ulcerative colitis

scientific article published on February 2008

Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey

scientific article published on 28 July 2015

Endoscopic and pathologic changes of the upper gastrointestinal tract in Crohn's disease.

scientific article published on 03 February 2014

Endoscopic imaging of parasites in the human digestive tract

scientific article published on 27 August 2013

Enhanced Gastric Ghrelin Production and Secretion in Rats with Gastric Outlet Obstruction

scientific article published on November 4, 2011

Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pylori

scientific article published on 11 December 2010

Enhanced gastric ghrelin-induced c-Kit protein expression in rats with gastric outlet obstruction.

scientific article

Enhanced ghrelin expression and subsequent acid secretion in mice with genetic H(2)-receptor knockout

scientific article published on 25 September 2007

Enhanced ghrelin secretion in rats with cysteamine-induced duodenal ulcers

scientific article

Enhanced plasma ghrelin levels in Helicobacter pylori-colonized, interleukin-1-receptor type 1-homozygous knockout (IL-1R1-/-) mice

scientific article

Enhancement of Amoxicillin Resistance after Unsuccessful Helicobacter pylori Eradication

scientific article published in 2013

Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication

scientific article

Epstein–Barr Virus-Associated Gastritis: A Case Report

scientific article published on September 21, 2012

Erratum to “Effect of Telmisartan or Losartan for Treatment of Nonalcoholic Fatty Liver Disease: Fatty Liver Protection Trial by Telmisartan or Losartan Study (FANTASY)”

scholarly article published in International journal of endocrinology

Erratum to: Four-year maintenance treatment with adalimumab in Japanese patients with moderately to severely active ulcerative colitis.

scientific article

Esophageal melanosis, an endoscopic finding associated with squamous cell neoplasms of the upper aerodigestive tract, and inactive aldehyde dehydrogenase-2 in alcoholic Japanese men.

scientific article published in July 2005

Esophageal varices and portal hypertensive gastropathy associated with hepatic veno-occlusive disease after allogeneic hematopoietic stem cell transplantation.

scientific article published on 7 February 2008

Establishment of novel prediction system of intestinal absorption in humans using human intestinal tissues

scientific article

Evaluating the severity of nonalcoholic steatohepatitis with superparamagnetic iron oxide-enhanced magnetic resonance imaging

scientific article published on December 2008

Evaluations of capsule endoscopy software in reducing the reading time and the rate of false negatives by inexperienced endoscopists

scientific article

Evidence-based clinical practice guidelines for Crohn’s disease, integrated with formal consensus of experts in Japan

scientific article published on October 23, 2012

Evidence-based clinical practice guidelines for inflammatory bowel disease.

scientific article published on 10 February 2018

Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice

scientific article published on 04 December 2007

Exclusive increase of CX3CR1+CD28-CD4+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes

scientific article published on 01 July 2007

Fasting Gastric pH of Japanese Subjects Stratified by IgG Concentration Against Helicobacter pylori and Pepsinogen Status

scientific article published on December 1, 2011

FecA1, a bacterial iron transporter, determines the survival of Helicobacter pylori in the stomach

scientific article published on 23 December 2011

First trough level of infliximab at week 2 predicts future outcomes of induction therapy in ulcerative colitis-results from a multicenter prospective randomized controlled trial and its post hoc analysis

scientific article published on 11 July 2015

Four-year maintenance treatment with adalimumab in Japanese patients with moderately to severely active ulcerative colitis

scientific article

Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

scientific article

Free cholesterol accumulation in liver sinusoidal endothelial cells exacerbates acetaminophen hepatotoxicity via TLR9 signaling.

scientific article published on 26 May 2017

Functional gastrointestinal disorders (FGID): progress in diagnosis and treatments. Topics: II. Current status and future prospective of medical care of the representative disorders; 3. Functional dyspepsia

scientific article published in January 2013

Gastric epithelial cell modality and proton pump inhibitor

scientific article published on May 2008

Gatifloxacin-based triple therapy as a third-line regimen for Helicobacter pylori eradication

scientific article

Gemcitabine as first-line chemotherapy in elderly patients with unresectable pancreatic carcinoma

scientific article published on 15 June 2010

Gene expression associated with the decrease in malignant phenotype of human liver cancer cells following stimulation with a histone deacetylase inhibitor.

scientific article published on January 2005

Genotype-Associated Differential NKG2D Expression on CD56+CD3+ Lymphocytes Predicts Response to Pegylated-Interferon/Ribavirin Therapy in Chronic Hepatitis C.

scientific article published on 12 May 2015

Ghrelin and oxidative stress in gastrointestinal tract

scientific article published on April 29, 2010

Granulocytapheresis is useful as an alternative therapy in patients with steroid-refractory or -dependent ulcerative colitis

scientific article published in May 2004

Granulocyte and monocyte adsorption apheresis therapy modulates monocyte-derived dendritic cell function in patients with ulcerative colitis

scientific article published in April 2009

H. pylori motility analysis

scientific article published in November 2005

H. pylori-Eradication Therapy Increases RUNX3 Expression in the Glandular Epithelial Cells in Enlarged-Fold Gastritis

scientific article

Hand-assisted versus conventional laparoscopic restorative proctocolectomy for ulcerative colitis

scientific article published on 01 February 2009

Helicobacter pylori and Gastric Mucosa-associated Lymphoid Tissue (MALT) Lymphoma: Updated Review of Clinical Outcomes and the Molecular Pathogenesis

scientific article

Helicobacter pylori and microcirculation

scientific article published on 25 August 2009

Helicobacter pylori eradication restored sonic hedgehog expression in the stomach

scientific article published on 01 April 2007

Helicobacter pylori eradication therapy

scientific article published on April 2010

Helicobacter pylori resistance to rifabutin in the last 7 years.

scientific article

Helicobacter pylori, chronic atrophic gastritis, inactive aldehyde dehydrogenase-2, macrocytosis and multiple upper aerodigestive tract cancers and the risk for gastric cancer in alcoholic Japanese men

scientific article published on 01 February 2007

Hemorrhagic colonic ulcers caused by dasatinib for chronic myelogenous leukemia

scientific article published on 8 September 2010

Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice

scientific article published in August 2008

Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone

scientific article published on June 2004

Hepatocellular carcinoma in Keio affiliated hospitals--diagnosis, treatment, and prognosis of this disease

scientific article published on September 2009

Herbal cardiotonic pills prevent gut ischemia/reperfusion-induced hepatic microvascular dysfunction in rats fed ethanol chronically

scientific article

Heterozygous Thr 135 Ala polymorphism at leucine-rich repeat (LRR) in genomic DNA of toll-like receptor 4 in patients with poorly-differentiated gastric adenocarcinomas.

scientific article

Histological complete response in a case of advanced gastric cancer treated by chemotherapy with S-1 plus low-dose cisplatin and radiation

scientific article

Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease.

scientific article published on July 2009

Homology model of the DNA gyrase enzyme of Helicobacter pylori, a target of quinolone-based eradication therapy.

scientific article published in May 2010

Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism

scientific article published on 6 June 2013

Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.

scientific article published on 10 July 2009

Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.

scientific article published in March 2004

IL-22-producing RORγt-dependent innate lymphoid cells play a novel protective role in murine acute hepatitis.

scientific article

Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine

scientific article published on October 2005

Identification by differential tissue proteome analysis of talin-1 as a novel molecular marker of progression of hepatocellular carcinoma

scientific article published on 15 August 2011

IgA plasma cells express the negative regulatory co-stimulatory molecule programmed cell death 1 ligand and have a potential tolerogenic role in the intestine

scientific article published on 12 August 2012

IgG4-negative autoimmune pancreatitis with sclerosing cholangitis and colitis: possible association with primary sclerosing cholangitis?

scientific article published on 15 May 2008

Ileal Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma with a Large-Cell Component That Regressed Spontaneously

scientific article published on 25 March 2010

Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease

scientific article

Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease

scientific article published in June 2010

Immune aspects of the pathogenesis of inflammatory bowel disease.

scientific article published on 26 October 2012

Immunosuppressants for therapy of patients with ulcerative colitis

scientific article published in May 2005

Impact of inflammatory bowel disease on Japanese patients' quality of life: results of a patient questionnaire survey

scientific article

Improvement of gastrointestinal quality of life scores in cases of Helicobacter pylori-positive functional dyspepsia after successful eradication therapy

scientific article published in November 2005

In vivo visualization of trophozoites in patients with amoebic colitis by using a newly developed endocytoscope

scientific article published on 25 June 2010

Increased expression and cellular localization of lipocalin-type prostaglandin D synthase in Helicobacter pylori-induced gastritis

scientific article

Individualized treatment based on CYP3A5 single-nucleotide polymorphisms with tacrolimus in ulcerative colitis

Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells

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Induction of matrix metalloproteinase-1 gene transcription by tumour necrosis factor alpha via the p50/p50 homodimer of nuclear factor-kappa B in activated human hepatic stellate cells

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Induction therapy with twice-daily interferon-beta does not improve the therapeutic efficacy of consensus interferon monotherapy for chronic hepatitis C.

scientific article published in September 2006

Infliximab for pediatric patients with Crohn's disease: A Phase 3, open-label, uncontrolled, multicenter trial in Japan

scientific article published in PLoS ONE

Infliximab therapy for intestinal, neurological, and vascular involvement in Behcet disease: Efficacy, safety, and pharmacokinetics in a multicenter, prospective, open-label, single-arm phase 3 study

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Influence of habitual drinking and viral hepatitis type C in the progression of liver cirrhosis

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Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis

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Innate immunity in inflammatory bowel disease: state of the art.

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Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice

scientific article published on 01 August 2003

Intermittent Granulocyte and Monocyte Apheresis Versus Mercaptopurine for Maintaining Remission of Ulcerative Colitis: A Pilot Study

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Introduction and overview: recent advances in the immunotherapy of inflammatory bowel disease

scientific article published on March 1, 2003

Investigation of a High-Dose pH-Dependent-Release Mesalazine on the Induction of Remission in Active Crohn's Disease

scientific article published on 16 February 2016

Investigation of the possibility of human-beta defensin 2 (hBD2) as a molecular marker of gastric mucosal inflammation.

scientific article published in September 2005

Involvement of herbal medicine as a cause of mesenteric phlebosclerosis: results from a large-scale nationwide survey

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Is chemoradiation effective or harmful for stage VI gastric cancer patients?

scientific article published in May 2005

Is the dendritic cell a missing piece in the pathogenesis model of post-infectious irritable bowel syndrome?

scientific article published on 01 May 2012

Is there a role for apheresis in gastrointestinal disorders?

scientific article published on 01 May 2005

Lack of common NOD2 variants in Japanese patients with Crohn's disease

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Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells.

scientific article published on 21 May 2007

Lemon grass (Cymbopogon citratus) ameliorates murine spontaneous ileitis by decreasing lymphocyte recruitment to the inflamed intestine

scientific article published on July 2010

Leptin deficiency enhances sensitivity of rats to alcoholic steatohepatitis through suppression of metallothionein

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Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis.

scientific article published on 27 July 2016

Leukocytapheresis in ulcerative colitis: results of a multicenter double-blind prospective case-control study with sham apheresis as placebo treatment

scientific article published in June 2005

Limited capability of regional lymph nodes to eradicate metastatic cancer cells.

scientific article published in November 2004

Lipocalin 2 prevents intestinal inflammation by enhancing phagocytic bacterial clearance in macrophages

scientific article published on 13 October 2016

Lipopolysaccharides stimulate adrenomedullin synthesis in intestinal epithelial cells: release kinetics and secretion polarity

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Long-term follow-up of allogeneic hematopoietic stem cell transplantation for de novo acute myelogenous leukemia with a conditioning regimen of total body irradiation and granulocyte colony-stimulating factor-combined high-dose cytarabine

scientific article published in June 2008

Long-term prognosis of Crohn's disease

scientific article published on 01 March 2011

Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy.

scientific article published on 26 May 2012

Long-term retention of adalimumab treatment and associated prognostic factors for 1189 patients with Crohn's disease

scientific article published on 31 October 2017

Long-term safety and efficacy of adalimumab for intestinal Behçet's disease in the open label study following a phase 3 clinical trial

scientific article published on 12 June 2017

Long-term safety and efficacy of adalimumab in Japanese patients with moderate to severe Crohn's disease

scientific article published on 27 May 2014

Long-term strict monitoring of plasma ghrelin and other serological markers of gastric diseases after Helicobacter pylori eradication.

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Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease

scientific article published on August 2008

Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis

scientific article published on January 1, 2003

Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients.

scientific article published on 3 July 2008

Lymphatic marker podoplanin/D2-40 in human advanced cirrhotic liver- Re-evaluations of microlymphatic abnormalities

scientific article published on November 8, 2010

Macrophage-Derived IL-18 Targeting for the Treatment of Crohns Disease

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Macrophages and dendritic cells emerge in the liver during intestinal inflammation and predispose the liver to inflammation.

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Management and treatment of ulcerative colitis. 3. Immunosuppressive agents

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Mechanism and therapeutic strategy of second failure of infliximab treatment for Crohn's disease

scientific article published on 01 March 2012

Melanosis and squamous cell neoplasms of the upper aerodigestive tract in Japanese alcoholic men.

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Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cells

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MicroRNAs in Hepatobiliary and Pancreatic Cancers

scientific article published on September 16, 2011

Microscopic colitis with granuloma which responded to steroid therapy

scientific article published on 14 September 2007

Minimally invasive surgery for esophageal epiphrenic diverticulum: the results of 133 patients in 25 published series and our experience

scientific article published on October 21, 2012

Moderate dietary temperance effectively prevents relapse of Crohn disease: a prospective study of patients in remission

scientific article published on 01 May 2007

Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset

scientific article published on 27 January 2010

Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14 macrophage activation.

scientific article published on 26 September 2012

Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis

scientific article published on 01 August 2003

Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients.

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Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column

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MyD88-dependent interleukin-10 production from regulatory CD11b⁺Gr-1(high) cells suppresses development of acute cerulein pancreatitis in mice

scientific article published on 25 September 2012

NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity

scientific article published on March 7, 2011

National survey of alcoholic liver disease in Japan

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New mechanism of transforming growth factor-beta signaling in hepatoma: Dramatic up-regulation of tumor initiating cells and epidermal growth factor receptor expression

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Non-tuberculous mycobacterial infection localized in small intestine developing after allogeneic bone marrow transplantation

scientific article published on 15 June 2010

Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells

scientific article published on 29 October 2007

Nonpathogenic Escherichia coli strain Nissle1917 prevents murine acute and chronic colitis.

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Novel pathophysiological concepts of inflammatory bowel disease

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Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease

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Obesity, type 2 diabetes, age, and female gender: significant risk factors in the development of alcoholic liver cirrhosis

scientific article published on 9 February 2012

On-treatment predictions of success in peg-interferon/ribavirin treatment using a novel formula

scientific article (publication date: 7 January 2010)

Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis

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Partial regression of duodenal lesions of intestinal follicular lymphoma after antibiotic treatment

scientific article published on October 1, 2010

Past rifampicin dosing determines rifabutin resistance of Helicobacter pylori

scientific article published on 14 January 2009

Pathology and pathophysiology of inflammatory bowel diseases. Development of inflammatory bowel disease due to disruption of the intestinal immuno-regulatory mechanism

scientific article published in January 2009

Pathophysiological role of human beta-defensins 2 in gastric mucosa

scientific article published on 01 December 2004

Pathophysiology of inflammatory bowel diseases and the therapeutic strategy

scientific article published in March 2004

Pentoxifylline prevents pig serum-induced rat liver fibrosis by inhibiting interleukin-6 production

scientific article published on 12 February 2009

Percutaneous endoscopic gastrostomy under steady pressure automatically controlled endoscopy: First clinical series

scientific article published on February 2016

Persistent oxidative stress in the corpus mucosa is evoked by long-term treatment of H. pylori-infected patients with proton pump inhibitors.

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Persistent retention of colitogenic CD4+ memory T cells causes inflammatory bowel diseases to become intractable

scientific article published on June 2009

Pharmacokinetics and safety of single and multiple doses of Asacol tablets in Japanese healthy volunteers

scientific article published in August 2009

Plasma Free Myristic Acid Proportion Is a Predictor of Nonalcoholic Steatohepatitis

scientific article published on April 23, 2011

Plasma ghrelin concentration correlates with the levels of serum pepsinogen I and pepsinogen I/II ratio--a possible novel and non-invasive marker for gastric atrophy.

scientific article published in September 2004

Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: A pilot study

scientific article published on 01 June 2007

Possible molecular mechanism of the relationship between NS5B polymorphisms and early clearance of hepatitis C virus during interferon plus ribavirin treatment

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Potential of 3,4-dihydroxy-phenyl lactic acid for ameliorating ischemia-reperfusion-induced microvascular disturbance in rat mesentery

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Predicting outcomes to optimize disease management in inflammatory bowel disease in Japan: their differences and similarities to Western countries.

scientific article published on 30 April 2018

Prediction of Effect of Pegylated Interferon Alpha-2b plus Ribavirin Combination Therapy in Patients with Chronic Hepatitis C Infection

scientific article published on December 2, 2011

Prediction of fasting gastric pH using serum biological markers

scientific article published on November 1, 2010

Prediction of survival and complications after percutaneous endoscopic gastrostomy in an individual by using clinical factors with an artificial neural network system

scientific article published in November 2009

Pregnancy outcome in women with inflammatory bowel disease treated with anti-tumor necrosis factor and/or thiopurine therapy: a multicenter study from Japan

scientific article published on 27 April 2016

Progressive liver failure induced by everolimus for renal cell carcinoma in a 58-year-old male hepatitis B virus carrier

scientific article published on March 14, 2013

Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus

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Protective effects of dihydroxylphenyl lactic acid and salvianolic acid B on LPS-induced mesenteric microcirculatory disturbance in rats

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Proton pump inhibitor-amoxicillin-clarithromycin versus proton pump inhibitor-amoxicillin-metronidazole as first-line Helicobacter pylori eradication therapy

scientific article published on March 30, 2012

Psychological aspects of inflammatory bowel disease

scientific article published on January 2007

Quinolone-Based Third-Line Therapy for Helicobacter pylori Eradication

scientific article published on 28 February 2009

Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients.

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Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab

scientific article published in July 2008

Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells

scientific article published on December 2012

Real-world Experience of Anti-tumor Necrosis Factor Therapy for Internal Fistulas in Crohn's Disease: A Retrospective Multicenter Cohort Study

scientific article published on 27 October 2017

Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells

scientific article published on 7 June 2011

Reliability, validity, and responsiveness of the Japanese version of the Inflammatory Bowel Disease Questionnaire.

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Retinoic acid contributes to the induction of IL-12-hypoproducing dendritic cells

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Retinoic acid formation from retinol in the human gastric mucosa: role of class IV alcohol dehydrogenase and its relevance to morphological changes

scientific article published on 28 April 2005

Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis

scientific article published in November 2007

Risk and management of intra-abdominal abscess in Crohn's disease treated with infliximab.

scientific article published in May 2014

Risk factors for decreased bone mineral density in inflammatory bowel disease: A cross-sectional study.

scientific article published on 13 January 2015

Risk of squamous cell carcinoma of the upper aerodigestive tract in cancer-free alcoholic Japanese men: an endoscopic follow-up study

scientific article published on 01 November 2006

Role of enhanced visibility in evaluating polyposis syndromes using a newly developed contrast image capsule endoscope

scientific article published on 17 April 2012

Role of erythrocytes as a reservoir for ribavirin and relationship with adverse reactions in the early phase of interferon combination therapy for chronic hepatitis C virus infections

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Safety and Tolerability of Nafamostat Mesilate and Heparin as Anticoagulants in Leukocytapheresis for Ulcerative Colitis: Post Hoc Analysis of a Large-Scale, Prospective, Observational Study

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Safety and efficacy of leukocytapheresis in elderly patients with ulcerative colitis: the impact in steroid-free elderly patients

scientific article published on 6 February 2018

Safety and usefulness of balloon endoscopy in Crohn's disease patients with postoperative ileal lesions

Safety of Adalimumab and Predictors of Adverse Events in 1693 Japanese Patients with Crohn's Disease

scientific article published on 09 March 2016

Sargramostim in patients with Crohn's disease: results of a phase 1-2 study

scientific article published on 8 April 2009

Second-line chemotherapy for refractory small cell neuroendocrine carcinoma of the esophagus that relapsed after complete remission with irinotecan plus cisplatin therapy: Case report and review of the literature

scientific article published on October 30, 2012

Serum Immunoglobulin A Concentration Is an Independent Predictor of Liver Fibrosis in Nonalcoholic Steatohepatitis Before the Cirrhotic Stage

scientific article published on June 15, 2011

Serum Nitrate/Nitrite Concentration Correlates with Gastric Juice Nitrate/Nitrite: A Possible Marker for Mutagenesis of the Proximal Stomach

scientific article published on April 14, 2011

Seven days triple therapy for eradication of Helicobacter pylori does not alter the disease activity of patients with inflammatory bowel disease

scientific article published on 10 October 2018

Severe alcoholic hepatitis in Japan: prognosis and therapy

scientific article published in December 2005

Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion.

scientific article published on June 2009

Sitafloxacin and garenoxacin may overcome the antibiotic resistance of Helicobacter pylori with gyrA mutation

scientific article published on 2 February 2009

Steroid-refractory extensive enteritis complicated by ulcerative colitis successfully treated with adalimumab

scientific article published on 23 October 2017

Structural features of the NAD-dependent in situ retinoic acid supply system in esophageal mucosa

scientific article published on 13 October 2009

Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis

scientific article published on 2 June 2013

Successful application of laparoscopic surgery to the treatment of Crohn's disease with fistulas

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Successful treatment of a large hyperplastic polyp in the jejunum by using single-balloon enteroscopy

scientific article published on December 31, 2010

Superoxide anion and reactive oxygen species and redox regulation in the liver

scientific article published in January 2006

Suppression of myeloid cell leukemia-1 (Mcl-1) enhances chemotherapy-associated apoptosis in gastric cancer cells

scientific article published on April 24, 2012

Suppressive effect of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) on hepatitis C virus replication

scientific article published on September 1, 2013

Surveillance using trimodal imaging endoscopy after endoscopic submucosal dissection for superficial gastric neoplasia

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Systemically circulating colitogenic memory CD4+T cells may be an ideal target for the treatment of inflammatory bowel diseases

scientific article published on December 2009

T-helper 17 and interleukin-17-producing lymphoid tissue inducer-like cells make different contributions to colitis in mice

scientific article published on 28 July 2012

TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression

scientific article published on February 2014

TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease

scientific article published on May 2013

TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease

scientific article published in April 2010

Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice

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Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement

scientific article published on 01 December 2002

Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.

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The 2nd edition of consensus statements for the diagnosis and management of intestinal Behçet's disease: indication of anti-TNFα monoclonal antibodies

scientific article published on 18 August 2013

The 5C Concept and 5S Principles in Inflammatory Bowel Disease Management

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The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease

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The role of microRNAs in gastrointestinal cancers.

scientific article published on 16 January 2009

The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.

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The use of infliximab in the prevention of postsurgical recurrence in polysurgery Crohn's disease patients: a pilot open-labeled prospective study

scientific article published on 11 January 2012

The use of water-soluble contrast enema without pretreatment for the diagnosis of colon disease

scientific article published on 01 September 2007

Therapeutic benefit of sulfasalazine for patients with primary sclerosing cholangitis

scientific article published on 01 April 2006

Therapeutic effect of lecithinized superoxide dismutase against colitis.

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Therapeutic efficacy of infliximab on active Crohn's disease under nutritional therapy

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Therapeutic efficacy of infliximab on patients with short duration of Crohn's disease: a Japanese multicenter survey

scientific article published on 06 March 2008

Therapeutic strategies for functional dyspepsia and the introduction of the Rome III classification

scientific article published on June 2006

Therapeutic strategies for severe alcoholic hepatitis

scientific article published on August 15, 2011

Timely colonoscopy leads to faster identification of bleeding diverticulum

scientific article published in November 2013

Tofacitinib induction and maintenance therapy in East Asian patients with active ulcerative colitis: subgroup analyses from three phase 3 multinational studies.

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Transforming Growth Factor β and Ras/MEK/ERK Signaling Regulate the Expression Level of a Novel Tumor Suppressor Lefty

scientific article published on July 1, 2012

Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats

scientific article published on August 2004

Transmural Pressure Loading Enhances Gastric Mucosal Cell Proliferation

scientific article published on May 30, 2012

Treatment guidelines in inflammatory bowel disease: the Japanese perspectives

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Treatment of hepatitis C virus with peg-interferon and ribavirin combination therapy significantly affects lipid metabolism

scientific article published on 5 November 2008

Treatment of ulcerative colitis by feeding with germinated barley foodstuff: first report of a multicenter open control trial

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Treatment of ulcerative colitis patients by long-term administration of germinated barley foodstuff: multi-center open trial

scientific article published on November 1, 2003

Twice-daily Budesonide 2-mg Foam Induces Complete Mucosal Healing in Patients with Distal Ulcerative Colitis

scientific article published on 16 November 2015

Two amino acids mutation of ferric uptake regulator determines Helicobacter pylori resistance to metronidazole

scientific article published on 26 August 2010

Ulcerative colitis and Crohn's disease

scientific article published in May 2005

Ulcerative colitis. Which makes patients happier, surgery or anti-TNF therapy?

scientific article published on 4 March 2014

Ulcerative colitis: prevention of relapse.

scientific article published on May 2013

Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis

scientific article published on June 2008

Utility of quantitative 99mTc-phytate scintigraphy to diagnose early-stage non-alcoholic steatohepatitis

scientific article published in January 2009

Validity of activity indices in ulcerative colitis: comparison of clinical and endoscopic indices

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Value of computed tomography-derived estimated liver volume/standard liver volume ratio for predicting the prognosis of adult fulminant hepatic failure in Japan

scientific article published on 01 December 2005

Vedolizumab in Japanese patients with ulcerative colitis: A Phase 3, randomized, double-blind, placebo-controlled study

scientific article published on 26 February 2019

[A case of chronic colonic pseudo-obstruction due to amyloidosis successfully treated with neostigmine]

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[A case of fulminant hepatitis E treated with artificial liver support]

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[A case of intrahepatic cholangiocarcinoma effectively treated by hepatic arterial infusion chemotherapy]

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[Endoscopic diagnosis of colitic cancer and dysplasia]

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[Endoscopic therapy for gastroesophageal reflux disease]

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[Eradication therapy for the improvement of quality of life in cases of Helicobacter pylori-positive functional dyspepsia]

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[Expectation of video capsule endoscopy for diagnosis of NSAID induced enteropathy]

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[Ghrelin - a novel appetite-stimulating hormone which also affects gastrointestinal functions]

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[New therapeutic strategies for inflammatory bowel diseases]

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[Pathogenic roles of intestinal macrophages in inflammatory bowel disease]

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[Sonic hedgehog expression in H. pylori-colonized gastric mucosa of Mongolian gerbils]

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p53 Protein accumulation, cancer multiplicity, and aldehyde dehydrogenase-2 genotype in Japanese alcoholic men with early esophageal squamous cell carcinoma

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p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice

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