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List of works by Steven Idell

Active α-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids

scientific article published on 30 August 2013

Adult respiratory distress syndrome: do selective anticoagulants help?

scientific article published on January 2002

Caveolin-1-derived peptide limits development of pulmonary fibrosis

scientific article published on 01 December 2019

Coagulation, fibrinolysis, and fibrin deposition in acute lung injury

scientific article

Correlation of apical fluid-regulating channel proteins with lung function in human COPD lungs

scientific article

Counterpoint: should fibrinolytics be routinely administered intrapleurally for management of a complicated parapneumonic effusion? No

scientific article published on January 2014

Deletion of FoxN1 in the thymic medullary epithelium reduces peripheral T cell responses to infection and mimics changes of aging

scientific article

Dose dependency of outcomes of intrapleural fibrinolytic therapy in new rabbit empyema models.

scientific article published on 24 June 2016

Effects of Extracellular DNA on Plasminogen Activation and Fibrinolysis ⬇️

scientific article published on October 5, 2011

Endothelial cell protein C receptor opposes mesothelioma growth driven by tissue factor

scientific article published on 28 March 2013

Endothelium and disordered fibrin turnover in the injured lung: newly recognized pathways

scientific article

Expression and regulation of epithelial Na+ channels by nucleotides in pleural mesothelial cells

scientific article published on 16 October 2008

Fibrin Turnover and Organization of Pleural Injury: Bench to Bedside.

scientific article published on 18 January 2018

Formulation for a novel inhaled peptide therapeutic for idiopathic pulmonary fibrosis.

scientific article published on 23 August 2017

Glycogen Synthase Kinase-3β Inhibition with 9-ING-41 Attenuates the Progression of Pulmonary Fibrosis

scientific article published on 12 December 2019

Increased expression of plasminogen activator inhibitor-1 (PAI-1) is associated with depression and depressive phenotype in C57Bl/6J mice

scientific article published on 16 November 2019

Induction of tissue factor by urokinase in lung epithelial cells and in the lungs

scientific article published on March 2010

Inhibition of Glycogen Synthase Kinase 3β Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia-Mediated Pleural Injury in Mice

scientific article

Interferon-γ promotes double-stranded RNA-induced TLR3-dependent apoptosis via upregulation of transcription factor Runx3 in airway epithelial cells

scientific article published on 28 October 2016

Intrapleural adenoviral delivery of human plasminogen activator inhibitor-1 exacerbates tetracycline-induced pleural injury in rabbits ⬇️

scientific article published on September 20, 2012

KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

scientific article published on 4 July 2017

LOX-1 Deletion Improves Neutrophil Responses, Enhances Bacterial Clearance, and Reduces Lung Injury in a Murine Polymicrobial Sepsis Model ⬇️

scientific article published on May 16, 2011

Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator.

scientific article

Lipoprotein receptor-related protein 1 regulates collagen 1 expression, proteolysis, and migration in human pleural mesothelial cells

scientific article published on February 2012

Mechanism of fibroblast inflammatory responses to Pseudomonas aeruginosa elastase

scientific article published on 02 January 2014

Mesomesenchymal transition of pleural mesothelial cells is PI3K and NF-κB dependent

scientific article published on 17 April 2015

Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

scientific article published on 20 February 2020

Myo5b Transports Fibronectin-Containing Vesicles and Facilitates FN1 Secretion from Human Pleural Mesothelial Cells

scientific article published on 27 April 2022

Myocardin Is Involved in Mesothelial-Mesenchymal Transition of Human Pleural Mesothelial Cells

scientific article published on 01 July 2019

Nebulization of Single-Chain Tissue-Type and Single-Chain Urokinase Plasminogen Activator for Treatment of Inhalational Smoke-Induced Acute Lung Injury

scientific article published on 30 April 2018

Novel aspects of urokinase function in the injured lung: role of α2-macroglobulin

scientific article

Organizing empyema induced in mice by Streptococcus pneumoniae: effects of plasminogen activator inhibitor-1 deficiency

scientific article published on 13 May 2016

Pathogenesis of pleural fibrosis

scientific article

Perfluorochemical-facilitated plasminogen activator delivery to the airways: A novel treatment for inhalational smoke-induced acute lung injury

scientific article published on 01 January 2020

Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyema.

scientific article published on 18 April 2019

Plasminogen activator inhibitor-1 deficiency augments visceral mesothelial organization, intrapleural coagulation, and lung restriction in mice with carbon black/bleomycin-induced pleural injury

scientific article published on February 2014

Plasminogen activator inhibitor-1 in cigarette smoke exposure and influenza A virus infection-induced lung injury

scientific article published on May 2015

Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs

scientific article

Plasminogen-plasmin system in the pathogenesis and treatment of lung and pleural injury

scientific article published on 16 March 2013

Post-transcriptional regulation of plasminogen activator inhibitor type-1 expression in human pleural mesothelial cells

scientific article published on 23 October 2009

Post-transcriptional regulation of urokinase-type plasminogen activator receptor expression in lipopolysaccharide-induced acute lung injury

scientific article published on 21 November 2008

Precision-guided, Personalized Intrapleural Fibrinolytic Therapy for Empyema and Complicated Parapneumonic Pleural Effusions: The Case for the Fibrinolytic Potential.

scientific article published in July 2017

Protein kinase D is increased and activated in lung epithelial cells and macrophages in idiopathic pulmonary fibrosis

scientific article

Rebuttal from Drs Colice and Idell

scientific article published on January 2014

Regulation of Urokinase Expression at the Posttranscription Level by Lung Epithelial Cells ⬇️

scientific article published on December 23, 2011

Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system

scientific article published on 2 December 2011

Regulation of epithelial sodium channels in urokinase plasminogen activator deficiency

scientific article published on 29 August 2014

Regulation of intrapleural fibrinolysis by urokinase-alpha-macroglobulin complexes in tetracycline-induced pleural injury in rabbits

scientific article published on 07 August 2009

Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1.

scientific article published on 08 May 2013

Regulation of p53-mediated changes in the uPA-fibrinolytic system and in lung injury by loss of surfactant protein C expression in alveolar epithelial cells.

scientific article published on 6 April 2017

Regulation of plasminogen activator inhibitor-1 expression by tumor suppressor protein p53.

scientific article published on 9 May 2008

Regulation of urokinase receptor expression by p53: novel role in stabilization of uPAR mRNA. ⬇️

scientific article

Regulation of urokinase receptor expression by phosphoglycerate kinase

scientific article published on 5 February 2004

Regulation of urokinase receptor expression by phosphoglycerate kinase is independent of its catalytic activity

scientific article published on 10 June 2005

Regulation of urokinase receptor expression by protein tyrosine phosphatases

scientific article

Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex.

scientific article published on 25 June 2013

Single-chain urokinase in empyema induced by Pasturella multocida

scientific article published on 01 October 2009

Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: role of the human SULT1A3.

scientific article published on 17 December 2010

Sulfation of nitrotyrosine: biochemistry and functional implications

scientific article published on October 2007

Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits.

scientific article published in April 2015

Targeting plasminogen activator inhibitor-1 in tetracycline-induced pleural injury in rabbits.

scientific article published on 31 August 2017

The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability

scientific article published on 03 October 2008

The pathogenesis of pleural space loculation and fibrosis

scientific article published on July 2008

The time course of resolution of adhesions during fibrinolytic therapy in tetracycline-induced pleural injury in rabbits.

scientific article

The urokinase receptor supports tumorigenesis of human malignant pleural mesothelioma cells

scientific article

Thrombin down-regulates tissue factor pathway inhibitor expression in a PI3K/nuclear factor-κB-dependent manner in human pleural mesothelial cells

scientific article published in June 2015

Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection

scientific article published on 16 October 2015

Tissue factor pathway inhibitor attenuates the progression of malignant pleural mesothelioma in nude mice

scientific article published on 18 August 2011

Transcription Factor Runx3 Is Induced by Influenza A Virus and Double-Strand RNA and Mediates Airway Epithelial Cell Apoptosis

scientific article published on 8 December 2015

Translational Research in Pleural Infection and Beyond

scientific article

Update on acute lung injury and critical care medicine 2009.

scientific article published on May 2010

Urokinase Plasminogen Activator Regulates Pulmonary Arterial Contractility and Vascular Permeability in Mice ⬇️

scientific article published on May 26, 2011

Urokinase induces its own expression in Beas2B lung epithelial cells

scientific article published on August 2002

Urokinase receptor mRNA stability involves tyrosine phosphorylation in lung epithelial cells

scientific article

Urokinase-type plasminogen activator potentiates lipopolysaccharide-induced neutrophil activation

scientific article published in June 2003

Wood Bark Smoke Induces Lung and Pleural Plasminogen Activator Inhibitor 1 and Stabilizes Its mRNA in Porcine Lung Cells ⬇️

scientific article published on August 1, 2011

p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis

scientific article published on 5 March 2017

tPA regulates pulmonary vascular activity through NMDA receptors ⬇️

scientific article published on May 13, 2011

δ ENaC: a novel divergent amiloride-inhibitable sodium channel ⬇️

scientific article published on September 14, 2012

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