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List of works by David Borsook

A 'BOLD' experiment in defining the utility of fMRI in drug development

scientific article

A Simple and Objective Method for Reproducible Resting State Network (RSN) Detection in fMRI ⬇️

scientific article published on December 12, 2011

A critical evaluation of validity and utility of translational imaging in pain and analgesia: Utilizing functional imaging to enhance the process

scientific article

A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study

scientific article published on 11 May 2010

A future without chronic pain: neuroscience and clinical research.

scientific article published on May 2012

A key role of the basal ganglia in pain and analgesia--insights gained through human functional imaging

scientific article

A new electronic diary tool for mapping and tracking spatial and temporal head pain patterns in migraine

scientific article published on 20 August 2014

A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements ⬇️

scientific article published on May 24, 2011

A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices ⬇️

scientific article published on 06 April 2011

A role for fMRI in optimizing CNS drug development

scientific article

A statistical framework for optimal design matrix generation with application to fMRI.

scientific article published on 18 March 2010

Abdominal Pain, the Adolescent and Altered Brain Structure and Function

scientific article published on 31 May 2016

Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy

scientific article published on 23 May 2014

Activation of pial and dural macrophages and dendritic cells by CSD (67 chrs).

scientific article published on 2 February 2018

Adriamycin injection into the medial cord of the brachial plexus: computed tomography-guided targeted pain therapy

scientific article

Age- and sex-related differences in the presentation of paediatric migraine: A retrospective cohort study

scientific article

Alterations in brain structure and functional connectivity in prescription opioid-dependent patients

scientific article

Altered hypothalamic functional connectivity with autonomic circuits and the locus coeruleus in migraine

scientific article

An approach to localizing corneal pain representation in human primary somatosensory cortex.

scientific article

Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial

scientific article published on April 2015

Anesthesia and perioperative stress: Consequences on neural networks and postoperative behaviors ⬇️

scientific article published on August 19, 2010

Anesthesia, brain changes, and behavior: Insights from neural systems biology

scientific article published on 8 February 2017

Antineuropathic effects of the antibiotic derivative spicamycin KRN5500.

scientific article

Author Correction: Metabolic and Addiction Indices in Patients on Opioid Agonist Medication-Assisted Treatment: A Comparison of Buprenorphine and Methadone

scientific article published on 01 May 2020

Autologous Serum Tears for Treatment of Photoallodynia in Patients with Corneal Neuropathy: Efficacy and Evaluation with In Vivo Confocal Microscopy.

scientific article published on 20 February 2015

Aversion-Related Circuitry in the Cerebellum: Responses to Noxious Heat and Unpleasant Images ⬇️

scientific article published on March 9, 2011

BOLD responses in somatosensory cortices better reflect heat sensation than pain.

scientific article

Behavioral and pharmacological characterization of a distal peripheral nerve injury in the rat.

scientific article published in May 2005

Biomarkers for chronic pain and analgesia. Part 1: the need, reality, challenges, and solutions

scientific article published on March 1, 2011

Biomarkers for chronic pain and analgesia. Part 2: how, where, and what to look for using functional imaging

scientific article published on March 1, 2011

Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report

scientific article published on 16 November 2019

Brain Changes in Responders vs. Non-Responders in Chronic Migraine: Markers of Disease Reversal

scientific article published on 06 October 2016

Brain Imaging in Migraine Research ⬇️

scientific article published on October 1, 2010

Brain changes after spinal cord injury, a quantitative meta-analysis and review

scientific article published on 24 April 2018

Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy.

scientific article published on 30 November 2015

Brain network alterations in the inflammatory soup animal model of migraine

scientific article

Brain resting-state connectivity in the development of secondary hyperalgesia in healthy men

scientific article published on 10 January 2019

Brain signatures of threat-safety discrimination in adolescent chronic pain

scientific article published on 01 March 2020

Breaking down the barriers: fMRI applications in pain, analgesia and analgesics

scientific article

Brodmann area 10: Collating, integrating and high level processing of nociception and pain

scientific article published on 30 November 2017

C-Fiber Assays in the Cornea vs. Skin

scientific article published on 12 November 2019

CNS Measures of Pain Responses Pre- and Post-Anesthetic Ketamine in a Patient with Complex Regional Pain Syndrome.

scientific article

CNS animal fMRI in pain and analgesia ⬇️

scientific article published on November 30, 2010

CNS response to a thermal stressor in human volunteers and rats may predict the clinical utility of analgesics

article

Calcitonin Gene-Related Peptide Modulates Heat Nociception in the Human Brain - An fMRI Study in Healthy Volunteers

scientific article

Can Functional Magnetic Resonance Imaging Improve Success Rates in CNS Drug Discovery?

scientific article

Capsaicin-induced thermal hyperalgesia and sensitization in the human trigeminal nociceptive pathway: an fMRI study

scientific article

Capturing Pain in the Cortex during General Anesthesia: Near Infrared Spectroscopy Measures in Patients Undergoing Catheter Ablation of Arrhythmias

scientific article

Capturing brain metrics of neuropathic pain using nuclear magnetic resonance

scientific article

Challenges of functional imaging research of pain in children

scientific article

Children With Chronic Pain: Response Trajectories After Intensive Pain Rehabilitation Treatment

scientific article published in November 2017

Chronic (neuropathic) corneal pain and blepharospasm: Five case reports ⬇️

scientific article published on July 12, 2011

Circles of engagement: Childhood pain and parent brain.

scientific article published on 16 June 2016

Clinical features and sex differences in pediatric post-traumatic headache: A retrospective chart review at a Boston area concussion clinic

scientific article published on 22 December 2019

Cluster headache: a review of neuroimaging findings

scientific article

Colocalized structural and functional changes in the cortex of patients with trigeminal neuropathic pain

scientific article

Color-selective photophobia in ictal vs interictal migraineurs and in healthy controls

scientific article published on 01 October 2018

Common Brain Mechanisms of Chronic Pain and Addiction

scientific article

Common hippocampal structural and functional changes in migraine ⬇️

scientific article published on 04 July 2012

Comparison of evoked vs. spontaneous tics in a patient with trigeminal neuralgia (tic doloureux).

scientific article

Completing the Pain Circuit: Recent Advances in Imaging Pain and Inflammation beyond the Central Nervous System

scientific article published on 29 October 2013

Concurrent functional and structural cortical alterations in migraine ⬇️

scientific article published on May 23, 2012

Contribution of Loss of Large Fiber Function to Pain in 2 Samples of Oncology Patients

scientific article published on 01 January 2019

Cortical projections of functionally identified thalamic trigeminovascular neurons: implications for migraine headache and its associated symptoms

scientific article

Cortico-Cortical Connections of Primary Sensory Areas and Associated Symptoms in Migraine

scientific article published on November 2016

Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain

scientific article

Decreased Brain Neurokinin-1 Receptor Availability in Chronic Tennis Elbow

scientific article published on 22 September 2016

Delineating conditions and subtypes in chronic pain using neuroimaging

scientific article published on 01 July 2019

Diffuse optical tomography activation in the somatosensory cortex: specific activation by painful vs. non-painful thermal stimuli

scientific article

Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: Implications for photophobia ⬇️

scientific article published on February 17, 2011

Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

scientific article published on 15 June 2020

Distraction analgesia in chronic pain patients: the impact of catastrophizing

scientific article published in December 2014

Effects of naltrexone on food intake and body weight gain in olanzapine-treated rats ⬇️

scientific article published on June 21, 2012

Emotional pain without sensory pain--dream on?

scientific article published on January 2009

Endometriosis and pain in the adolescent- striking early to limit suffering: A narrative review

scientific article published on 17 December 2019

Enhanced false discovery rate using Gaussian mixture models for thresholding fMRI statistical maps

scientific article published on 06 March 2009

Enhancing Choice and Outcomes for Therapeutic Trials in Chronic Pain: N-of-1 + Imaging (+ i)

scientific article published on 09 January 2020

Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring

scientific article

Excitatory neurotransmitters in brain regions in interictal migraine patients

scientific article published on 30 June 2009

Fear and Reward Circuit Alterations in Pediatric CRPS.

scientific article

Female migraineurs show lack of insular thinning with age

scientific article published on July 2015

Focused ultrasound induced opening of the blood-brain barrier disrupts inter-hemispheric resting state functional connectivity in the rat brain

scientific article published on 29 May 2018

Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents

scientific article

Frontal Lobe Hemodynamic Responses to Painful Stimulation: A Potential Brain Marker of Nociception.

scientific article

Functional imaging of pain and analgesia--a valid diagnostic tool?

scientific article

Functional imaging of the human trigeminal system: opportunities for new insights into pain processing in health and disease

scientific article

Functional imaging of the trigeminal system: applications to migraine pathophysiology

scientific article

Functional magnetic resonance imaging measures of the effects of morphine on central nervous system circuitry in opioid-naive healthy volunteers

scientific article published in July 2006

Habenula functional resting-state connectivity in pediatric CRPS

scientific article published on 23 October 2013

Harnessing the placebo effect in pediatric migraine clinic

scientific article

Headache Professional Societies: Ethical Challenges and Suggested Solutions

scientific article published in September 2017

Her versus his migraine: multiple sex differences in brain function and structure

scientific article

How Close Are We in Utilizing Functional Neuroimaging in Routine Clinical Diagnosis of Neuropathic Pain? ⬇️

scientific article published on June 1, 2011

Identifying Rodent Resting-State Brain Networks with Independent Component Analysis

scientific article published on 12 December 2017

Imaging drugs with and without clinical analgesic efficacy.

scientific article published on 17 August 2011

Implications of the putamen in pain and motor deficits in complex regional pain syndrome

scientific article published on 01 March 2020

Improved characterization of BOLD responses for evoked sensory stimuli

scientific article published on 23 October 2009

In child and adult migraineurs the somatosensory cortex stands out … again: An arterial spin labeling investigation

scientific article

Increased Amplitude of Thalamocortical Low-Frequency Oscillations in Patients with Migraine.

scientific article published on July 2016

Increased Functional Activation of Limbic Brain Regions during Negative Emotional Processing in Migraine

scientific article

Insights and advances in post-traumatic headache: research considerations

scientific article published on February 2014

Interictal dysfunction of a brainstem descending modulatory center in migraine patients

scientific article

Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome.

scientific article

Ketamine and chronic pain--going the distance

scientific article published on July 2009

Longitudinal Evaluation of Pain, Flare-Up, and Emotional Health in Fibrodysplasia Ossificans Progressiva: Analyses of the International FOP Registry

scientific article published on 01 March 2019

Losses and gains: chronic pain and altered brain morphology

scientific article published on 29 October 2013

Lost but making progress--Where will new analgesic drugs come from?

scientific article

Mayer waves reduce the accuracy of estimated hemodynamic response functions in functional near-infrared spectroscopy.

scientific article published on 22 July 2016

Metabolic and Addiction Indices in Patients on Opioid Agonist Medication-Assisted Treatment: A Comparison of Buprenorphine and Methadone

scientific article published on 27 March 2020

Microstructural White Matter Abnormalities in the Dorsal Cingulum of Adolescents with IBS

scientific article published on 01 July 2018

Migraine Attacks the Basal Ganglia ⬇️

scientific article published on September 21, 2011

Migraine Mistakes: Error Awareness

scientific article published on 18 September 2013

Migraine Tweets – What can online behavior tell us about disease? ⬇️

scientific article published on November 7, 2012

Migraine changes the brain: neuroimaging makes its mark

scientific article

Migraine in the Young Brain: Adolescents vs. Young Adults

article by Elisabeth Colon et al published 2019 in Frontiers in Human Neuroscience

Migraine photophobia originating in cone-driven retinal pathways

scientific article published on 17 May 2016

Migraine: Maladaptive Brain Responses to Stress ⬇️

scientific article published on October 1, 2012

Migraine: multiple processes, complex pathophysiology

scientific article published on April 2015

Migrainomics - identifying brain and genetic markers of migraine

scientific article published on 17 November 2017

Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine

scientific article published on 18 November 2011

Modulation of brain function by targeted delivery of GABA through the disrupted blood-brain barrier

scientific article published on 16 January 2019

Modulation of brain networks by sumatriptan-naproxen in the inflammatory soup migraine model

scientific article published on 01 September 2019

Molecular and functional PET-fMRI measures of placebo analgesia in episodic migraine: Preliminary findings

scientific article published on 15 November 2017

Morphine Attenuates fNIRS Signal Associated With Painful Stimuli in the Medial Frontopolar Cortex (medial BA 10)

Neural circuitry underlying pain modulation: expectation, hypnosis, placebo

scientific article published on 01 May 2003

Neural mechanism for hypothalamic-mediated autonomic responses to light during migraine

scientific article published on 26 June 2017

Neurochemical pathways that converge on thalamic trigeminovascular neurons: potential substrate for modulation of migraine by sleep, food intake, stress and anxiety

scientific article

Neuroimaging of the periaqueductal gray: state of the field

scientific article

Neuroimaging revolutionizes therapeutic approaches to chronic pain

scientific article

Neuropeptides and Neurotransmitters That Modulate Thalamo-Cortical Pathways Relevant to Migraine Headache

scientific article published on May 2017

Nitroglycerin as a comparative experimental model of migraine pain: From animal to human and back

scientific article published on 13 February 2019

Nocebo effect in randomized clinical trials of antidepressants in children and adolescents: systematic review and meta-analysis.

scientific article

Noninvasive mapping of human trigeminal brainstem pathways

scientific article

Objectifying chronic pain: from the patient to diagnostic metrics

scientific article published in May 2013

Ocular neuropathic pain

scientific article

Oculofacial Pain: Corneal Nerve Damage Leading to Pain Beyond the Eye.

scientific article published on October 2016

Opioidergic tone and pain susceptibility: interactions between reward systems and opioid receptors

scientific article

Pain and analgesia: the value of salience circuits

scientific article published on 7 March 2013

Pain and spinal cord imaging measures in children with demyelinating disease

scientific article

Pain and suicidality: insights from reward and addiction neuroscience.

scientific article published on July 2013

Pain facilitation brain regions activated by nalbuphine are revealed by pharmacological fMRI.

scientific article

Pain imaging: future applications to integrative clinical and basic neurobiology

scientific article

Pain response measured with arterial spin labeling

scientific article

Pain: Do ACE inhibitors exacerbate complex regional pain syndrome?

scientific article published on 01 June 2009

Pain: the past, present and future

scientific article

Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects.

scientific article

Parental Attitudes About Placebo Use in Children

scientific article published on 9 November 2016

Pediatric Pain Screening Tool: rapid identification of risk in youth with pain complaints.

scientific article published in August 2015

Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges

scientific article

Phenotyping central nervous system circuitry in chronic pain using functional MRI: considerations and potential implications in the clinic

scientific article

Primary Somatosensory Cortices Contain Altered Patterns of Regional Cerebral Blood Flow in the Interictal Phase of Migraine

scientific article published on 15 September 2015

Probing Intrinsic Resting-State Networks in the Infant Rat Brain

scientific article published on 18 October 2016

Psychological processing in chronic pain: a neural systems approach.

scientific article published on 27 December 2013

Psychosocial stress and its relationship to gambling urges in individuals with pathological gambling

scientific article published in July 2010

Random Forest Segregation of Drug Responses May Define Regions of Biological Significance.

scientific article published on 9 March 2016

Rapid treatment-induced brain changes in pediatric CRPS.

scientific article published on 17 December 2014

Reasons to Believe: The Potential of Imaging in CNS Drug Development

article

Reply to Letter: "Surgically Induced Neuropathic Pain: Understanding the Perioperative Process".

scientific article published on 5 December 2013

Responsivity of Periaqueductal Gray Connectivity Is Related to Headache Frequency in Episodic Migraine

scientific article published on 13 February 2018

Resting-State Functional Connectivity in the Infant Brain: Methods, Pitfalls, and Potentiality.

scientific article published on 14 August 2017

Retrospective accounts of initial subjective effects of opioids in patients treated for pain who do or do not develop opioid addiction: a pilot case-control study

scientific article

Reward and aversion processing in patients with post-traumatic stress disorder: functional neuroimaging with visual and thermal stimuli

Reward-aversion circuitry in analgesia and pain: implications for psychiatric disorders

scientific article

Robust Reproducible Resting State Networks in the Awake Rodent Brain ⬇️

scientific article published on October 18, 2011

Robust, unbiased general linear model estimation of phMRI signal amplitude in the presence of variation in the temporal response profile

scientific article published in June 2010

Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report

scientific article published on 07 June 2019

Scale-free amplitude modulation of low-frequency fluctuations in episodic migraine

scientific article published on 01 October 2019

Secondary effects on brain physiology caused by focused ultrasound-mediated disruption of the blood-brain barrier

scientific article published on 26 May 2020

Segmentally arranged somatotopy within the face representation of human primary somatosensory cortex

Shifting brain circuits in pain chronicity

scientific article published on 12 July 2019

Short separation regression improves statistical significance and better localizes the hemodynamic response obtained by near-infrared spectroscopy for tasks with differing autonomic responses

scientific article

Signal valence in the nucleus accumbens to pain onset and offset

scientific article published on 28 January 2008

Somatotopic activation in the human trigeminal pain pathway.

scientific article published in September 2002

Specific and somatotopic functional magnetic resonance imaging activation in the trigeminal ganglion by brush and noxious heat

scientific article published on 01 August 2003

Specificity of hemodynamic brain responses to painful stimuli: a functional near-infrared spectroscopy study

scientific article

Subliminal (latent) processing of pain and its evolution to conscious awareness.

scientific article published on 21 February 2018

Surgically induced neuropathic pain: understanding the perioperative process

scientific article published on March 2013

Taking the headache out of migraine

scientific article

Targeted manipulation of pain neural networks: The potential of focused ultrasound for treatment of chronic pain

scientific article published on 11 June 2020

Test-retest reliability of evoked heat stimulation BOLD fMRI.

scientific article

Thalamic sensitization transforms localized pain into widespread allodynia

scientific article published on July 2010

The Challenges and Opportunities

The Corneal Pain System. Part I: The Missing Piece of the Dry Eye Puzzle ⬇️

scientific article published on January 8, 2012

The Insula: A "Hub of Activity" in Migraine

scientific article published on 19 August 2015

The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations

scientific article

The Promise of Effective Pain Treatment Outcomes: Rallying Academic Centers to Lead the Charge

scientific article

The cerebellum and addiction: insights gained from neuroimaging research

scientific article

The cerebellum and pain: passive integrator or active participator?

scientific article

The cornucopia of central disinhibition pain - An evaluation of past and novel concepts

scientific article published on 12 August 2020

The effect of antinociceptive drugs tested at different times after nerve injury in rats

scientific article published in July 2005

The effect of naltrexone on body fat mass in olanzapine-treated schizophrenic or schizoaffective patients: a randomized double-blind placebo-controlled pilot study.

scientific article

The failing cascade: Comorbid post traumatic stress- and opioid use disorders

scientific article published on 04 May 2019

The human amygdala and pain: evidence from neuroimaging

scientific article published on 25 October 2012

The migraine brain in transition: girls vs boys

scientific article

The migraine eye: distinct rod-driven retinal pathways' response to dim light challenges the visual cortex hyperexcitability theory

scientific article published on 01 March 2019

The missing p in psychiatric training: why it is important to teach pain to psychiatrists

scientific article

The neurovascular response is attenuated by focused ultrasound-mediated disruption of the blood-brain barrier

scientific article published on 11 July 2019

The pain imaging revolution: advancing pain into the 21st century

scientific article

The young brain and concussion: imaging as a biomarker for diagnosis and prognosis

scientific article

Threat Response System: Parallel Brain Processes in Pain vis-à-vis Fear and Anxiety

scientific article published on 20 February 2018

Transient and persistent pain induced connectivity alterations in pediatric complex regional pain syndrome

scientific article

Trigeminal neuropathic pain alters responses in CNS circuits to mechanical (brush) and thermal (cold and heat) stimuli

scientific article published on 01 October 2006

Understanding Migraine through the Lens of Maladaptive Stress Responses: A Model Disease of Allostatic Load ⬇️

scientific article published on January 26, 2012

Using NMR approaches to drive the search for new CNS therapeutics.

scientific article

Using prerecorded hemodynamic response functions in detecting prefrontal pain response: a functional near-infrared spectroscopy study. ⬇️

scientific article published on 16 October 2017

Utilizing brain imaging for analgesic drug development

scientific article

Visuospatial and Sensory Integration Tasks in Patients With Schizophrenia or Schizoaffective Disorder: Relationship to Body Mass Index and Smoking

When pain gets stuck: the evolution of pain chronification and treatment resistance

scientific article published on 01 December 2018

Yohimbine-induced amygdala activation in pathological gamblers: a pilot study

scientific article

‘Hot Feet – Hot Brain’: Gene and brain dysfunction in erythromelalgia ⬇️

scientific article published on March 9, 2012

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