List of works - Huaqiang Xu

A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2

scientific article published on 27 April 2022

A new era for GPCR research: structures, biology and drug discovery ⬇️

scientific article published on March 1, 2012

A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein ⬇️

scientific article published on February 16, 2012

A single GAL4 dimer can maximally activate transcription under physiological conditions ⬇️

scientific article published on August 15, 1995

A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor

scientific article published on 25 November 2020

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho ⬇️

scientific article published on September 17, 2012

Couple Dynamics: PPARγ and Its Ligand Partners ⬇️

scientific article published on January 11, 2012

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy

scientific article published on 17 August 2020

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors ⬇️

scientific article published on May 19, 2011

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway ⬇️

scientific article published on June 8, 2011

GABAB receptor pas de deux: insights from high-resolution structures

scientific article published on 10 July 2020

Hormone- and antibody-mediated activation of the thyrotropin receptor

scientific article published on 08 August 2022

Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1

scientific article published on 23 December 2021

LRP5 and LRP6 in development and disease ⬇️

scientific article published on January 1, 2013

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

scientific article published on 23 September 2021

Lipid modification in Wnt structure and function ⬇️

scientific article published on April 1, 2013

Modulation of β-Catenin Signaling by Glucagon Receptor Activation ⬇️

scientific article published on March 16, 2012

Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor

scientific article published on 18 June 2021

Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3

scientific article published on 15 May 2022

Molecular mechanisms of fentanyl mediated β-arrestin biased signaling

scientific article published on 10 April 2020

Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor

scientific article published on 20 August 2021

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2

scientific article published on 25 February 2022

Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment

scientific article published on 29 April 2020

Structural Basis for the Inhibition of the RNA-Dependent RNA Polymerase from SARS-CoV-2 by Remdesivir

scientific article published on 10 April 2020

Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins

scientific article published on 31 May 2022

Structural basis for activation of the growth hormone-releasing hormone receptor

scientific article published on 15 October 2020

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

scientific article

Structural basis of leukotriene B4 receptor 1 activation

scientific article published on 03 March 2022

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors ⬇️

scientific article published on November 6, 2001

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors