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List of works by Tara Arvedson

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys

scientific article published on 01 September 2020

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

scientific article published on 06 January 2010

Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing

scientific article published on 24 August 2017

Characterization of a Novel FLT3 BiTE® Antibody Construct for the Treatment of Acute Myeloid Leukemia

scientific article published on 09 June 2020

Classical and intermediate monocytes scavenge non-transferrin-bound iron and damaged erythrocytes

scientific article published on 18 April 2019

Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing

scientific article published on 01 April 2020

Design Rationale and Development Approach for Pegfilgrastim as a Long-Acting Granulocyte Colony-Stimulating Factor

scientific article

Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C

scientific article published on 20 August 2019

Hepcidin regulation in prostate and its disruption in prostate cancer.

scientific article

Hepcidin revisited, disulfide connectivity, dynamics, and structure

scientific article

High-Throughput Mass Spectrometric Analysis of Covalent Protein-Inhibitor Adducts for the Discovery of Irreversible Inhibitors: A Complete Workflow

scientific article published on 16 December 2015

IL-22 Regulates Iron Availability In Vivo through the Induction of Hepcidin

scientific article published on July 8, 2013

Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

scientific article published on 21 November 2017

Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT.

scientific article

Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor (CAR) T-cell Therapy for the Treatment of Acute Myeloid Leukemia

scientific article published on 26 June 2020

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

scientific article published on 18 July 2016

Oxidative folding of hepcidin at acidic pH.

scientific article published on January 2010

Serum hepcidin but not prohepcidin may be an effective marker for anemia of inflammation (AI).

scientific article

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

scientific article published on 19 August 2020

Systematic Study of the Glutathione (GSH) Reactivity of N-Arylacrylamides: 1. Effects of Aryl Substitution.

scientific article published on 18 November 2015

Systematic Study of the Glutathione (GSH) Reactivity of N-Phenylacrylamides: 2. Effects of Acrylamide Substitution

scientific article published on 23 September 2020

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

scientific article published on 30 October 2019

The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models

scientific article published on 01 September 2020