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List of works by Lionel Adès

A landscape of germline mutations in a cohort of inherited bone marrow failure patients

scientific article published on 16 November 2017

A multiparametric niche-like drug screening platform in acute myeloid leukemia

scientific article published in 2022

A phase II study of guadecitabine in higher-risk myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure

scientific article published on 07 February 2019

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

scientific article published on 01 July 2019

Allogeneic hematopoietic cell transplantation in patients age 60-70 years with de novo high-risk myelodysplastic syndrome or secondary acute myelogenous leukemia: comparison with patients lacking donors who received azacitidine

scientific article

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

scientific article

Are myelodysplastic syndromes and acute myeloid leukaemia occurring during the course of lymphoma always therapy related?

scientific article published on 23 September 2016

Auer rods and differentiation in acute promyelocytic leukemia

Azacitidine in untreated acute myeloid leukemia: a report on 149 patients

scientific article published on 06 February 2014

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

scientific article published on 27 April 2017

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

scientific article published on 7 April 2015

Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study.

scientific article published on 14 April 2017

Clonal architecture of chronic myelomonocytic leukemias

scientific article published on 14 January 2013

Clonal dominance is an adverse prognostic factor in acute myeloid leukemia treated with intensive chemotherapy

scientific article published on 24 June 2020

Comparison of TP53 mutations screening by functional assay of separated allele in yeast and next-generation sequencing in myelodysplastic syndromes

scientific article

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

scientific article published in April 2005

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.

scientific article

Epstein-Barr virus (EBV) reactivation in allogeneic stem-cell transplantation: relationship between viral load, EBV-specific T-cell reconstitution and rituximab therapy.

scientific article

Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison

scientific article

Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.

scientific article published on 15 September 2011

Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study

scientific article

Evolving characteristics and outcome of secondary acute promyelocytic leukemia (APL): A prospective analysis by the French-Belgian-Swiss APL group

scientific article

Exome analysis of treatment-related AML after APL suggests secondary evolution

scientific article published on 22 November 2018

Genetic analysis of therapy-related myeloid neoplasms occurring after intensive treatment for acute promyelocytic leukemia

scientific article published on 18 April 2018

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

scientific article published in 2021

Granulomonocytic progenitors are key target cells of azacytidine in higher risk myelodysplastic syndromes and acute myeloid leukemia

scholarly article by Ashfaq Ali et al published 26 February 2018 in Leukemia

Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia

scientific article published on 15 July 2011

Impact of baseline cytogenetic findings and cytogenetic response on outcome of high-risk myelodysplastic syndromes and low blast count AML treated with azacitidine

scientific article

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

scientific article published on 03 August 2020

Is Cytarabine Useful in the Treatment of Acute Promyelocytic Leukemia? Results of a Randomized Trial From the European Acute Promyelocytic Leukemia Group

article by Lionel Adès et al published 20 December 2006 in Journal of Clinical Oncology

Letter to the Editor: Allogeneic hematopoietic stem cell transplantation in elderly patients with acute myeloid leukemia or myelodysplastic syndromes: myth and reality

scientific article published on 30 July 2020

Limited efficacy and tolerance of imatinib mesylate in steroid-refractory sclerodermatous chronic GVHD.

scientific article

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

scientific article published on 12 November 2012

Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and Daunorubicin in the treatment of nonelderly APL patients

scientific article

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

scientific article published on 01 January 2020

Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

scientific article

Myelodysplastic syndromes

scientific article published on 21 March 2014

Outcome of acute promyelocytic leukemia (APL) in children and adolescents: an analysis in two consecutive trials of the European APL Group.

scientific article published on 2 April 2012

Outcome of patients with high risk Myelodysplastic Syndrome (MDS) and advanced Chronic Myelomonocytic Leukemia (CMML) treated with decitabine after azacitidine failure.

scientific article published on 16 February 2015

Predictive factors of response and survival among chronic myelomonocytic leukemia patients treated with azacitidine

scientific article published on 12 February 2013

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents.

scientific article published on 25 April 2018

Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

scientific article published on 12 October 2010

Prognostic impact of JAK2V617F mutation in myelodysplatic syndromes: A matched case control study

scientific article published on 30 August 2013

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

scientific article

Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

scientific article

Role of reduced-intensity conditioning allogeneic hematopoietic stem-cell transplantation in older patients with de novo myelodysplastic syndromes: an international collaborative decision analysis

scientific article published on 24 June 2013

Single agent talacotuzumab demonstrates limited efficacy but considerable toxicity in elderly high-risk MDS or AML patients failing hypomethylating agents

scientific article published on 03 December 2019

Slow relapse in acute myeloid leukemia with inv(16) or t(16;16).

scientific article published on 16 July 2009

Sotatercept with long-term extension for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes: a phase 2, dose-ranging trial

scientific article published on 10 January 2018

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

scientific article published on 11 January 2019

Tc1 clonal T cell expansion during chronic graft-versus-host disease-associated hypereosinophilia

scientific article published on 24 January 2014

The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience

scientific article published on 01 December 2012

Treatment of advanced myelodysplastic syndrome with demethylating agents: azacitidine

scientific article published on October 2012

Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM).

scientific article published on 27 July 2010

Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience

scientific article

When can real-time quantitative RT-PCR effectively define molecular relapse in acute promyelocytic leukemia patients? (Results of the French Belgian Swiss APL Group).

scientific article

mutation is not associated with prolonged complete remission in acute myeloid leukemia patients treated with hypomethylating agents

scholarly article by Pedro Henrique Prata et al published October 2018 in Haematologica

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