Search filters

List of works by Akira Shibuya

A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells

scholarly article

A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.

scientific article published on 22 December 2006

A mathematical model for dynamics of soluble form of DNAM-1 as a biomarker for graft-versus-host disease

scientific article published on 10 February 2020

A pro-inflammatory role of Fcα/μR on marginal zone B cells in sepsis

scientific article published on 21 December 2017

A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory

scientific article

Accelerated tumor growth in mice deficient in DNAM-1 receptor

scientific article

Activation of murine invariant NKT cells promotes susceptibility to candidiasis by IL-10 induced modulation of phagocyte antifungal activity

scientific article published on 6 May 2016

Activation of neutrophils by a novel triggering immunoglobulin-like receptor MAIR-IV

scientific journal article

Allergin-1 Immunoreceptor Suppresses House Dust Mite-Induced Allergic Airway Inflammation

scientific article published on 03 January 2020

Allergin-1 inhibits TLR2-mediated mast cell activation and suppresses dermatitis

scientific article published on 8 November 2016

Allergin-1 on mast cells suppresses house dust mite-induced airway hyperresponsiveness in mice

scientific article published on 01 August 2018

Allergy inhibitory receptor-1 inhibits autoantibody production via upregulation of apoptotic debris clearance by macrophages

scientific article published on 16 December 2018

An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions

scientific article

Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor

scientific article

Apoptotic epithelial cells control the abundance of Treg cells at barrier surfaces

scientific article published on 8 February 2016

Autonomous regulation of IgE-mediated mast cell degranulation and immediate hypersensitivity reaction by an inhibitory receptor CD300a

scientific article published on 30 May 2019

B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fcα/μ receptor and in the absence of host cell contact.

scientific article published on December 2011

CD155 (PVR/Necl5) mediates a costimulatory signal in CD4+ T cells and regulates allergic inflammation.

scientific article published on 13 May 2015

CD155/CD226-interaction impacts on the generation of innate CD8(+) thymocytes by regulating iNKT-cell differentiation.

scientific article published on 22 December 2015

CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation

scientific article

CD226 interaction with CD155 impacts on retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches.

scientific article published on 17 February 2012

CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells

scientific article (publication date: 19 September 2003)

Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells

scientific article

Clec10a regulates mite-induced dermatitis

scientific article published on 01 December 2019

Comment on "CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions"

scientific article published on 01 April 2006

Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection

scientific article published on 16 January 2014

Critical role of DNAX accessory molecule-1 (DNAM-1) in the development of acute graft-versus-host disease in mice

scientific article

Critical role of M. tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b background of C57BL/6 mice.

scientific article

Critical role of activating immune receptor DNAM-1 in the development of acute GVHD

scientific article published on 01 May 2012

Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers

scientific article published on 23 April 2018

Cutting Edge: Involvement of the Immunoreceptor CD300c2 on Alveolar Macrophages in Bleomycin-Induced Lung Fibrosis

scientific article published on 22 November 2019

Development and Characterization of Novel Monoclonal Antibodies Against Human DNAM-1.

scientific article

Development and functions of natural killer cells

scientific article

Dual assemblies of an activating immune receptor, MAIR-II, with ITAM-bearing adapters DAP12 and FcRgamma chain on peritoneal macrophages

scientific article published on 01 January 2007

Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming

scientific article

Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation

scholarly article by Yoshiyuki Nakamura et al published 5 December 2018 in Cell Death and Disease

Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice

scholarly article

Establishment and characterization of a novel anti-DNAM-1 monoclonal antibody.

scientific article published on February 2013

Exploring the Gut Fungi-Lung Allergy Axis

scientific article published on 01 December 2018

Expression and function of Allergin-1 on human primary mast cells

scientific article

Expression and function of DNAM-1 on human B-lineage cells

scientific article published on 29 November 2019

Expression of DNAM-1 (CD226) on inflammatory monocytes

scientific article published on 08 December 2015

Expression of Fc receptor for immunoglobulin M in oligodendrocytes and myelin of mouse central nervous system

scientific article published in February 2003

Expression of a splicing isoform of MAIR-V (CD300LF), an inhibitory immunoglobulin-like receptor on myeloid cells

scientific article

Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain

scientific article published on 01 July 2018

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)

scientific article

Glycoprotein nmb Is Exposed on the Surface of Dormant Breast Cancer Cells and Induces Stem Cell-like Properties

scientific article published on 17 September 2018

Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE₂.

scientific article published on January 2014

HVJ-E containing PD-L1 siRNA inhibits immunosuppressive activities and elicits antitumor immune responses in glioma

scientific article published on 06 November 2020

High expression of soluble CD155 in estrogen receptor-negative breast cancer

scientific article published on 01 August 2019

Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family

scientific journal article

Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands

scientific journal article

Identification and isolation of splenic tissue-resident macrophage sub-populations by flow cytometry

scientific article published on 01 February 2019

Identification of phosphatidylserine as a ligand for the CD300a immunoreceptor.

scientific article published on 11 December 2011

Identification of the Fcalpha/muR isoform specifically expressed in the kidney tubules.

scientific article

IgM-Dependent Phagocytosis in Microglia Is Mediated by Complement Receptor 3, Not Fcα/μ Receptor.

scientific article published on 23 October 2015

Immune regulation by Fcα/μ receptor (CD351) on marginal zone B cells and follicular dendritic cells

scientific article

Immunoreceptor CD300a on mast cells and dendritic cells regulates neutrophil recruitment in a murine model of sepsis.

scientific article published on 11 November 2016

Improved protocol for the isolation of naïve follicular dendritic cells

scientific article published on 14 September 2016

Increased CD112 expression in methylcholanthrene-induced tumors in CD155-deficient mice

scientific article

Increased CD11b(+) Gr-1(+) cell population in the placenta after infection with Toxoplasma gondii

scientific article published on February 2015

Increased Soluble CD155 in the Serum of Cancer Patients

scientific article

Increased serum IgA in Fcα/μR-deficient mice on the (129 x C57BL/6) F1 genetic background

scientific article

Influence of MILR1 promoter polymorphism on expression levels and the phenotype of atopy

scientific article published on 10 July 2014

Ingested allergens must be absorbed systemically to induce systemic anaphylaxis

scientific article published on February 26, 2011

Inhibitory Immunoreceptors on Mast Cells in Allergy and Inflammation

Interferon-β promotes the survival and function of induced regulatory T cells

scientific article published in 2022

Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation

scientific article published on 27 August 2019

Involvement of CD300a Phosphatidylserine Immunoreceptor in Aluminum Salt Adjuvant-Induced Th2 Responses

scientific article published on 24 April 2015

Involvement of Fcα/μR (CD351) in autoantibody production

scientific article published on 27 October 2013

Involvement of pentraxin-3 in anti-neutrophil cytoplasmic antibody production induced by aluminum salt adjuvant

scientific article published on 28 August 2017

Isolation and characterization of naïve follicular dendritic cells

scientific article published on 19 December 2011

LFA-1 decreases the antigen dose for T cell activation in vivo

scientific article published on 21 July 2008

LFA-1-dependent lipid raft recruitment of DNAM-1 (CD226) in CD4+ T cell

scientific article published on 24 April 2006

Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches

scientific article published in 2023

Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient Kitw-sh/w-sh mice

scientific article

MAIR-II deficiency ameliorates cardiac remodelling post-myocardial infarction by suppressing TLR9-mediated macrophage activation

scientific article published on 02 November 2020

Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling

scientific article published on 5 May 2016

Mechanism of phosphatidylserine inhibition of IgE/FcεRI-dependent anaphylactic human basophil degranulation via CD300a.

scientific article

Molecular and functional characteristics of the Fcalpha/muR, a novel Fc receptor for IgM and IgA

scientific article

Molecular characteristics of IgA and IgM Fc binding to the Fcalpha/muR

scientific article (publication date: 23 June 2006)

Molecular characterization of the dimer formation of Fcα/μ receptor (CD351)

scientific article published on May 9, 2013

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo.

scientific article published on 06 April 2009

Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells.

scientific article

Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice

scientific article published on July 9, 2012

PPARβ/δ activation of CD300a controls intestinal immunity

scientific article

Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation

scientific journal article

Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation.

scientific article published on 19 April 2018

Positional identification of an asthma susceptibility gene on human chromosome 5q33.

scientific article

Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU.1 transcription factors in Langerhans cell commitment

scientific article

Regulation of Immune Responses by the Activating and Inhibitory Myeloid-Associate Immunoglobuline-Like Receptors (MAIR) (CD300)

scientific article

Reply to Seth et al.: DNAX accessory molecule-1 (DNAM-1) plays an important role in alloreactive CD8 T cells responsible for the exacerbation of acute graft-versus-host disease

scientific article

Requirement of the cytoplasmic portion for dimer formation of Fcalpha/micro receptor expressed on cell surface

scientific article

Requirement of the serine at residue 329 for lipid raft recruitment of DNAM-1 (CD226).

scientific article

Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3.

scientific article

Selective DNAM-1 expression on small peritoneal macrophages contributes to CD4 T cell costimulation

scientific article published in Scientific Reports

Selective suppression of oral allergen-induced anaphylaxis by Allergin-1 on basophils in mice

scientific article published on 01 March 2020

Serum under-O-glycosylated IgA1 level is not correlated with glomerular IgA deposition based upon heterogeneity in the composition of immune complexes in IgA nephropathy

scientific article

Soluble DNAM-1, as a Predictive Biomarker for Acute Graft-Versus-Host Disease

scientific article

Successful multilineage engraftment of human cord blood cells in pigs after in utero transplantation

scientific article published on April 15, 2003

Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells

scientific article published on 23 July 2020

Suppression of eosinophilic airway inflammation by treatment with alpha-galactosylceramide.

scientific article

TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT

scientific article published on 12 April 2018

Th1 and type 1 cytotoxic T cells dominate responses in T-bet overexpression transgenic mice that develop contact dermatitis

scientific article published on 01 January 2007

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

article by Hiromitsu Hara et al published 7 May 2007 in Nature Immunology

The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.

scientific article

The secretome of irradiated peripheral blood mononuclear cells attenuates activation of mast cells and basophils

scientific article published on 04 June 2022

Tie2 Signaling Enhances Mast Cell Progenitor Adhesion to Vascular Cell Adhesion Molecule-1 (VCAM-1) through α4β1 Integrin

scientific article

To the editor: TIGIT versus CD226: hegemony or coexistence?

scientific article

Toll-like receptor 4 and MAIR-II/CLM-4/LMIR2 immunoreceptor regulate VLA-4-mediated inflammatory monocyte migration

scientific article

Transgenic Overexpression of GATA-3 in T Lymphocytes Improves Autoimmune Glomerulonephritis in Mice with a BXSB/MpJ-Yaa Genetic Background

scientific article published on October 1, 2003

Treatment with alpha-galactosylceramide attenuates the development of bleomycin-induced pulmonary fibrosis

scientific article published in May 2004

Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor.

scientific article published on 25 October 2005

Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells

scientific article published on 01 March 2020

Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes

scientific article published on 03 December 2019

Unusual biochemical features and follicular dendritic cell expression of human Fcalpha/mu receptor

scientific article published on December 2007

[Immunoglobulin-like receptor, allergin-1 regulates the activation of mast cells]